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The map label for this gene is rsbRA [H]

Identifier: 159899324

GI number: 159899324

Start: 3565013

End: 3565840

Strand: Reverse

Name: rsbRA [H]

Synonym: Haur_2805

Alternate gene names: 159899324

Gene position: 3565840-3565013 (Counterclockwise)

Preceding gene: 159899326

Following gene: 159899323

Centisome position: 56.19

GC content: 50.48

Gene sequence:

>828_bases
ATGCAACCTATTCTTGAGCATATTCAAGCGCACCTTGATCGCTATGTCACCACCGCCACCGATCGCGTCTTCGCAGCCAA
AATCAATCTGTATCGTAGCTTTGGCTATGATCAATTACAGACCTCAATTCGCTATGCCTACACGGCCTTTGTGAGCGATC
TTAGTGCTGGTACGGTTGAGGCGATGCCCAATTTTCTGATGCGCATTGGCCCGCAACGCGCTGAGCAAGGCGCAACCGTT
GAAGATATTTTGTTCGGCATCAATATGGGCGTTGAAGTAATTACCGAAGATCTCAACGCGACGTTTGCCGATAATCCCGC
TGGATTATTGTGGTGGATGCAACAGATGCATGCGATTGTCTATACTGGCGCGATGAAACTCTCCGATACAATTCTCAAAG
CGCGTGAACAGCATATTCGTGAGCAGGCCAGCCAAATTGCCGAATTCTCAACCCCGATTATTCCACTTTCGCAAGGTGTA
TTAGTTGTCCCGTTGATTGGCGTTTTGGGCGAACAACGAGCCAGCCGCATTACCGAAGCCTTGTTGCAACGAATCAGCGA
GGAACAAGCCTCGACCGTATTGATCGATGTAACGGGGGTTCCGGTGGTTGATACTCAAGTGGCGCACAACTTAATTCAAT
CGGCTCAGGCTGCCAAATTGGTTGGAGCCGAAGTGTTATTAGTGGGCATTCGGCCTGAAATGGCCCAAACGTTGGTACAA
CTTGGCGTAAATTTGCAGGGCGTGCGCACCCAAGGCACGTTGCAAGCTGGGGTTGAATATGCCTTTGAGCGCCAGAAACG
CCAAAACGCTAAGCCGATGCGCCGCTAA

Upstream 100 bases:

>100_bases
TATGATGTTTTTTAGCCCTTGGTAATCAACTAAATACATTAGCGCCACTCTGATCAATCGCTATGTTCGATCACTGGTGC
CGCAACAACGGAGCCTATCG

Downstream 100 bases:

>100_bases
CTTAAGCCCAGATCTGCCCTAAATTGGTAGTACAATGAGTGCCAACAGAACCTGTGTGCGGCTCAGCGCCGAGTTGTTGC
TAGGTTCTCTCGCTGTAGCA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MQPILEHIQAHLDRYVTTATDRVFAAKINLYRSFGYDQLQTSIRYAYTAFVSDLSAGTVEAMPNFLMRIGPQRAEQGATV
EDILFGINMGVEVITEDLNATFADNPAGLLWWMQQMHAIVYTGAMKLSDTILKAREQHIREQASQIAEFSTPIIPLSQGV
LVVPLIGVLGEQRASRITEALLQRISEEQASTVLIDVTGVPVVDTQVAHNLIQSAQAAKLVGAEVLLVGIRPEMAQTLVQ
LGVNLQGVRTQGTLQAGVEYAFERQKRQNAKPMRR

Sequences:

>Translated_275_residues
MQPILEHIQAHLDRYVTTATDRVFAAKINLYRSFGYDQLQTSIRYAYTAFVSDLSAGTVEAMPNFLMRIGPQRAEQGATV
EDILFGINMGVEVITEDLNATFADNPAGLLWWMQQMHAIVYTGAMKLSDTILKAREQHIREQASQIAEFSTPIIPLSQGV
LVVPLIGVLGEQRASRITEALLQRISEEQASTVLIDVTGVPVVDTQVAHNLIQSAQAAKLVGAEVLLVGIRPEMAQTLVQ
LGVNLQGVRTQGTLQAGVEYAFERQKRQNAKPMRR
>Mature_275_residues
MQPILEHIQAHLDRYVTTATDRVFAAKINLYRSFGYDQLQTSIRYAYTAFVSDLSAGTVEAMPNFLMRIGPQRAEQGATV
EDILFGINMGVEVITEDLNATFADNPAGLLWWMQQMHAIVYTGAMKLSDTILKAREQHIREQASQIAEFSTPIIPLSQGV
LVVPLIGVLGEQRASRITEALLQRISEEQASTVLIDVTGVPVVDTQVAHNLIQSAQAAKLVGAEVLLVGIRPEMAQTLVQ
LGVNLQGVRTQGTLQAGVEYAFERQKRQNAKPMRR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 30356; Mature: 30356

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPILEHIQAHLDRYVTTATDRVFAAKINLYRSFGYDQLQTSIRYAYTAFVSDLSAGTVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHH
AMPNFLMRIGPQRAEQGATVEDILFGINMGVEVITEDLNATFADNPAGLLWWMQQMHAIV
HHHHHHHHHCHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
YTGAMKLSDTILKAREQHIREQASQIAEFSTPIIPLSQGVLVVPLIGVLGEQRASRITEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHH
LLQRISEEQASTVLIDVTGVPVVDTQVAHNLIQSAQAAKLVGAEVLLVGIRPEMAQTLVQ
HHHHHHHHHHCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHH
LGVNLQGVRTQGTLQAGVEYAFERQKRQNAKPMRR
HCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQPILEHIQAHLDRYVTTATDRVFAAKINLYRSFGYDQLQTSIRYAYTAFVSDLSAGTVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHH
AMPNFLMRIGPQRAEQGATVEDILFGINMGVEVITEDLNATFADNPAGLLWWMQQMHAIV
HHHHHHHHHCHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
YTGAMKLSDTILKAREQHIREQASQIAEFSTPIIPLSQGVLVVPLIGVLGEQRASRITEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHH
LLQRISEEQASTVLIDVTGVPVVDTQVAHNLIQSAQAAKLVGAEVLLVGIRPEMAQTLVQ
HHHHHHHHHHCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHH
LGVNLQGVRTQGTLQAGVEYAFERQKRQNAKPMRR
HCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]