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The map label for this gene is yfkE [H]

Identifier: 159899224

GI number: 159899224

Start: 3458545

End: 3459657

Strand: Reverse

Name: yfkE [H]

Synonym: Haur_2705

Alternate gene names: 159899224

Gene position: 3459657-3458545 (Counterclockwise)

Preceding gene: 159899225

Following gene: 159899211

Centisome position: 54.51

GC content: 44.38

Gene sequence:

>1113_bases
ATGAAACTGCGCTGGATTCATTACATGTTGTTGTTTGTGCCGTTGGCGGTGGTCGCTGAATTCTTTTTATATAACGAGAT
GTTGATTTTTGTTTTTTCAGCCTTGGCCTTAATTCCATTGGCTGGGTTTTTGGGCGAGGCGACCGAAGAGCTAGCGATTC
ACACTGGGCCAAAAATTGGTGGTTTGCTGAATGCGACACTTGGCAATGCTGCCGAATTGATCATCACGATTGTGGCATTG
AAAGCAGGTAAATTCGAGTTGGTCAAGGCTTCAATTACTGGCTCAATTATCGGTAATTTGCTCTTGATCATTGGGTTTAG
CTTCCTGCTTGGCGGCTTGAAGCATGGCAAGCAAAAGTTTGATCGTGGTCTAACTGGGATGTCGGCCTCGCTGATGACGC
TGGCAGTGATTGGTTTGATTATTCCAACCTTGTTTGAATTGTTCAAAGAAATCGCCGATCCCAATGTTGCGCTTGATGTG
TTTAAAACCCAAGTTGATGACCCACAACTACGGGCTATTTCAATTGGTGTGGCGGCGGTGTTGATCATCGTCTATATCTT
GAGTATGATCTACATTCTGCGTGATGGTGATTCGGGCACAATTTCACACACTGGCTTTGAAGAAACCGACGAAATCGAAA
GCCATAAAGCCACTATGAGCATTAAAGCCGCAGTTGGTATTTTGGCTGTCTGTACCTTAGCAATTGTCTTTATGAGTGAA
TTTTTGGTGGGTGTGGTCGAGCCAGTTGCCCGTTCGTTGGGCGTGCGCGAGTTATTCTTGGGGATTATCTTTATTCCAAT
TGTGGGCAACGTTGCCGAACACTTAGTTGGGGTTCAAGCAGCGCTCAAAAATAAAATGGATCTTTCAATGACGATTTCAT
TGGGATCAAGCACGCAAATTGCCCTGTTCGTTGCACCATTGTTGGTGTTTATTAGCATGCTGTTTGATCAGCAAATGACC
TTGTTCTTCAGCTTGTTTGAGGTGATGGTGCTTGGTTTGAGTGTGATTATTGCTACCTTTGTTTCAATGGATGGTGAGAG
TAATTGGCTAGAAGGAGCAATGTTGCTGGCGGTCTATATTATCGTTGGGATTGGCTTCTTCTTTGTCGGTTAA

Upstream 100 bases:

>100_bases
GATCTATAATCAACAGCGTATTGGCGAATGTCGATACGCTGTCGTCGTTAATCAGCCCTATAGGAAGTTCCTTGTTTCGC
TAGTGTGAGGATGATCCACG

Downstream 100 bases:

>100_bases
ACCGAAAACCCGTCTGTTGCAATCAATTCAACAGACGGGTTTATCATTTAATTATGGCGAGCAGCGTTTGGCTTTTTGAT
GTAGTCGATACCATCGCCTA

Product: calcium/cation antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKLRWIHYMLLFVPLAVVAEFFLYNEMLIFVFSALALIPLAGFLGEATEELAIHTGPKIGGLLNATLGNAAELIITIVAL
KAGKFELVKASITGSIIGNLLLIIGFSFLLGGLKHGKQKFDRGLTGMSASLMTLAVIGLIIPTLFELFKEIADPNVALDV
FKTQVDDPQLRAISIGVAAVLIIVYILSMIYILRDGDSGTISHTGFEETDEIESHKATMSIKAAVGILAVCTLAIVFMSE
FLVGVVEPVARSLGVRELFLGIIFIPIVGNVAEHLVGVQAALKNKMDLSMTISLGSSTQIALFVAPLLVFISMLFDQQMT
LFFSLFEVMVLGLSVIIATFVSMDGESNWLEGAMLLAVYIIVGIGFFFVG

Sequences:

>Translated_370_residues
MKLRWIHYMLLFVPLAVVAEFFLYNEMLIFVFSALALIPLAGFLGEATEELAIHTGPKIGGLLNATLGNAAELIITIVAL
KAGKFELVKASITGSIIGNLLLIIGFSFLLGGLKHGKQKFDRGLTGMSASLMTLAVIGLIIPTLFELFKEIADPNVALDV
FKTQVDDPQLRAISIGVAAVLIIVYILSMIYILRDGDSGTISHTGFEETDEIESHKATMSIKAAVGILAVCTLAIVFMSE
FLVGVVEPVARSLGVRELFLGIIFIPIVGNVAEHLVGVQAALKNKMDLSMTISLGSSTQIALFVAPLLVFISMLFDQQMT
LFFSLFEVMVLGLSVIIATFVSMDGESNWLEGAMLLAVYIIVGIGFFFVG
>Mature_370_residues
MKLRWIHYMLLFVPLAVVAEFFLYNEMLIFVFSALALIPLAGFLGEATEELAIHTGPKIGGLLNATLGNAAELIITIVAL
KAGKFELVKASITGSIIGNLLLIIGFSFLLGGLKHGKQKFDRGLTGMSASLMTLAVIGLIIPTLFELFKEIADPNVALDV
FKTQVDDPQLRAISIGVAAVLIIVYILSMIYILRDGDSGTISHTGFEETDEIESHKATMSIKAAVGILAVCTLAIVFMSE
FLVGVVEPVARSLGVRELFLGIIFIPIVGNVAEHLVGVQAALKNKMDLSMTISLGSSTQIALFVAPLLVFISMLFDQQMT
LFFSLFEVMVLGLSVIIATFVSMDGESNWLEGAMLLAVYIIVGIGFFFVG

Specific function: Unknown

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320075, Length=373, Percent_Identity=40.7506702412869, Blast_Score=249, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6324008, Length=390, Percent_Identity=27.9487179487179, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004798
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 39841; Mature: 39841

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRWIHYMLLFVPLAVVAEFFLYNEMLIFVFSALALIPLAGFLGEATEELAIHTGPKIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLLNATLGNAAELIITIVALKAGKFELVKASITGSIIGNLLLIIGFSFLLGGLKHGKQKF
HHHHHHHCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRGLTGMSASLMTLAVIGLIIPTLFELFKEIADPNVALDVFKTQVDDPQLRAISIGVAAV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
LIIVYILSMIYILRDGDSGTISHTGFEETDEIESHKATMSIKAAVGILAVCTLAIVFMSE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVGVVEPVARSLGVRELFLGIIFIPIVGNVAEHLVGVQAALKNKMDLSMTISLGSSTQI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHH
ALFVAPLLVFISMLFDQQMTLFFSLFEVMVLGLSVIIATFVSMDGESNWLEGAMLLAVYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IVGIGFFFVG
HHHHHHHHCC
>Mature Secondary Structure
MKLRWIHYMLLFVPLAVVAEFFLYNEMLIFVFSALALIPLAGFLGEATEELAIHTGPKIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLLNATLGNAAELIITIVALKAGKFELVKASITGSIIGNLLLIIGFSFLLGGLKHGKQKF
HHHHHHHCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRGLTGMSASLMTLAVIGLIIPTLFELFKEIADPNVALDVFKTQVDDPQLRAISIGVAAV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
LIIVYILSMIYILRDGDSGTISHTGFEETDEIESHKATMSIKAAVGILAVCTLAIVFMSE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVGVVEPVARSLGVRELFLGIIFIPIVGNVAEHLVGVQAALKNKMDLSMTISLGSSTQI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHH
ALFVAPLLVFISMLFDQQMTLFFSLFEVMVLGLSVIIATFVSMDGESNWLEGAMLLAVYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IVGIGFFFVG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]