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The map label for this gene is trpD

Identifier: 159899207

GI number: 159899207

Start: 3445835

End: 3446851

Strand: Direct

Name: trpD

Synonym: Haur_2688

Alternate gene names: 159899207

Gene position: 3445835-3446851 (Clockwise)

Preceding gene: 159899206

Following gene: 159899212

Centisome position: 54.29

GC content: 54.77

Gene sequence:

>1017_bases
ATGCAGATTCGCGATGCGATTATTACGGTTACCAATCGAACGGATTTAAGCCAAGACGATGCGGCGGCGGTGATGGAGCA
GATGATGAATGGCGAGGCCACGCCAGCCCAAATCGCGGCCTTGCTCACGGCGTTACATTTCAAAGGTGAAACTGACGCAG
AAATTGCTGGTATGGCCCAAGTGATGCGGGCTAAATCGCTTGCCGTGCCCCACGATGGCGGCGTGGTCGATACCTGTGGC
ACTGGTGGCGATCATTCAAATACCTTCAATATTTCAACGACTGCAGCGTTTGTGGCAGCAGGTGCAGGCGCAACCGTCGC
CAAACACGGCAATCGCGCTATGTCGTCGAAATGTGGATCAGCCGATGTGCTCGAAGGTTTGGGGGTCAATATCGAGCTTG
ATGCTGAAGGTGTGGCCCGCTGTTTGCGCCAAGCAGGCATCGGCTTTATGTTTGCGCCTAAGTTTCATCCCGCAATGCGT
TATGCTGGGCCAGTGCGCCGCGAAATTGGCATTCGCACGATTTTCAATGTCTTGGGGCCACTGACCAACCCAGCCCGCGC
CGAATATCAGGTGATTGGGGTTGCTAACGCAGGTTTGGCCGAAAAATTGGCCAATGCTCTAAGCAAAATGGGTATTCGCC
GTGCCTTGGTGGTGCATGGCAGCGATGGGCTTGATGAAATTTCAATCAGCGCCTCAACCTTGGTGTTTGATGTGCGAGCT
GGGGCTACTCCCCAAGCCTCGACAATTAGCCCTAGTGATTTTGGTCTAAGCCTTGCGCCGCGTGAAGCAATTGCTGGTGG
CTCAGTCGAGGAAAATGTGGCCATGACCAAGGCAATTCTTGAGGGTAGCGATACTGGCCCACGTCGCGATATTGTGCTCT
TGAATGCCGCCGCCGCATTGGTTGCTTGTGAACGCGCCGATTCGTTTGGCGAGGCTTTGCGTCAAGCTCAACAGGCCATC
GACACTGGCAGCGCCAATCAGCGTATGCAACGAATGATCGAGGCCAGCAACGGCTAG

Upstream 100 bases:

>100_bases
GACGTTGAGGTCGTAGGTTCGAATCCTATCACCCCGACCACTACAACGAGGGCAATTTGCTCTCGTTGTTTTTTTGTTGT
TTTGCTGCAAGGAGCCAACC

Downstream 100 bases:

>100_bases
CGTTGAGCGATCAATTGGCCGAGTGCTTGATTTTCACGCCAAATTGCCAGTGGTGAACGGGCTGGTTTAATCCAATGATC
AAGCTCAGCGATGCTAGCCG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQIRDAIITVTNRTDLSQDDAAAVMEQMMNGEATPAQIAALLTALHFKGETDAEIAGMAQVMRAKSLAVPHDGGVVDTCG
TGGDHSNTFNISTTAAFVAAGAGATVAKHGNRAMSSKCGSADVLEGLGVNIELDAEGVARCLRQAGIGFMFAPKFHPAMR
YAGPVRREIGIRTIFNVLGPLTNPARAEYQVIGVANAGLAEKLANALSKMGIRRALVVHGSDGLDEISISASTLVFDVRA
GATPQASTISPSDFGLSLAPREAIAGGSVEENVAMTKAILEGSDTGPRRDIVLLNAAAALVACERADSFGEALRQAQQAI
DTGSANQRMQRMIEASNG

Sequences:

>Translated_338_residues
MQIRDAIITVTNRTDLSQDDAAAVMEQMMNGEATPAQIAALLTALHFKGETDAEIAGMAQVMRAKSLAVPHDGGVVDTCG
TGGDHSNTFNISTTAAFVAAGAGATVAKHGNRAMSSKCGSADVLEGLGVNIELDAEGVARCLRQAGIGFMFAPKFHPAMR
YAGPVRREIGIRTIFNVLGPLTNPARAEYQVIGVANAGLAEKLANALSKMGIRRALVVHGSDGLDEISISASTLVFDVRA
GATPQASTISPSDFGLSLAPREAIAGGSVEENVAMTKAILEGSDTGPRRDIVLLNAAAALVACERADSFGEALRQAQQAI
DTGSANQRMQRMIEASNG
>Mature_338_residues
MQIRDAIITVTNRTDLSQDDAAAVMEQMMNGEATPAQIAALLTALHFKGETDAEIAGMAQVMRAKSLAVPHDGGVVDTCG
TGGDHSNTFNISTTAAFVAAGAGATVAKHGNRAMSSKCGSADVLEGLGVNIELDAEGVARCLRQAGIGFMFAPKFHPAMR
YAGPVRREIGIRTIFNVLGPLTNPARAEYQVIGVANAGLAEKLANALSKMGIRRALVVHGSDGLDEISISASTLVFDVRA
GATPQASTISPSDFGLSLAPREAIAGGSVEENVAMTKAILEGSDTGPRRDIVLLNAAAALVACERADSFGEALRQAQQAI
DTGSANQRMQRMIEASNG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=269, Percent_Identity=42.0074349442379, Blast_Score=199, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320561, Length=358, Percent_Identity=29.3296089385475, Blast_Score=139, Evalue=6e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_HERA2 (A9B148)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545454.1
- ProteinModelPortal:   A9B148
- SMR:   A9B148
- GeneID:   5734569
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_2688
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   HAUR316274:HAUR_2688-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35004; Mature: 35004

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRDAIITVTNRTDLSQDDAAAVMEQMMNGEATPAQIAALLTALHFKGETDAEIAGMAQ
CCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
VMRAKSLAVPHDGGVVDTCGTGGDHSNTFNISTTAAFVAAGAGATVAKHGNRAMSSKCGS
HHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEHHHHHHHCCCCCHHHHCCCHHHHCCCCC
ADVLEGLGVNIELDAEGVARCLRQAGIGFMFAPKFHPAMRYAGPVRREIGIRTIFNVLGP
CHHHHCCCCEEEECHHHHHHHHHHCCCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCC
LTNPARAEYQVIGVANAGLAEKLANALSKMGIRRALVVHGSDGLDEISISASTLVFDVRA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCEEEEEEEEC
GATPQASTISPSDFGLSLAPREAIAGGSVEENVAMTKAILEGSDTGPRRDIVLLNAAAAL
CCCCCCCCCCCCCCCCEECCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHH
VACERADSFGEALRQAQQAIDTGSANQRMQRMIEASNG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQIRDAIITVTNRTDLSQDDAAAVMEQMMNGEATPAQIAALLTALHFKGETDAEIAGMAQ
CCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
VMRAKSLAVPHDGGVVDTCGTGGDHSNTFNISTTAAFVAAGAGATVAKHGNRAMSSKCGS
HHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEHHHHHHHCCCCCHHHHCCCHHHHCCCCC
ADVLEGLGVNIELDAEGVARCLRQAGIGFMFAPKFHPAMRYAGPVRREIGIRTIFNVLGP
CHHHHCCCCEEEECHHHHHHHHHHCCCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCC
LTNPARAEYQVIGVANAGLAEKLANALSKMGIRRALVVHGSDGLDEISISASTLVFDVRA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCEEEEEEEEC
GATPQASTISPSDFGLSLAPREAIAGGSVEENVAMTKAILEGSDTGPRRDIVLLNAAAAL
CCCCCCCCCCCCCCCCEECCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHH
VACERADSFGEALRQAQQAIDTGSANQRMQRMIEASNG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA