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The map label for this gene is yfnC [H]

Identifier: 159899113

GI number: 159899113

Start: 3329024

End: 3330211

Strand: Direct

Name: yfnC [H]

Synonym: Haur_2594

Alternate gene names: 159899113

Gene position: 3329024-3330211 (Clockwise)

Preceding gene: 159899112

Following gene: 159899118

Centisome position: 52.45

GC content: 52.36

Gene sequence:

>1188_bases
ATGGCAACGCGGACAAGTGGGCAGGCTGTCGCTCTGACAGGCCTTTCGGTCATGGTAATGATGACATTTTCGCATGCCAT
GAATGATATGTGGACTTCACTGTTAGCGCCCTTACTGCCAAGTATTCGCGATACCTATCAGGTGAGTATTGGTCAAACTG
GCATTTTGGTGGCGATTTTGTCGTTTGCTGGCTCGATGCTTCAGCCCTTGCTTGGTGCGGTTGGCGATTATATTGATCGG
CGTTGGTTAGCGGCATTTGGCCCTGTGCTGACGGCGATCGGCCTAACCTTGATTGGCTATGTGCCCAATTTCTTTATGCT
GGGCGCGTTGATTATGCTTGGTGGTTTGGGCAGCGCAATTTTTCATCCGGCAGGAGCAGCCTATATCGCCATGGGCGCGA
ATCCTCAGCAACGTGGTTTGTTTGTTTCAATTTTTTCGGCTGGCGGCACGGTTGGCATGGCCTTTGGCCCCCTAATTGCT
GCCCAGTTTGATTTGGTGAGTTTGCCCTATTTGCTGCCCGTGGGAATTGCAGTTGGGGTTTTGACCTTCTTGATGATTCC
TTCAGCCAAGCAAAATCGCAGCCAACCCAAAACGTTGCGCGATTATATCAGCGTTTTTCAGGGGCCGTTGCGCTGGCTTT
GGTTTATGAGCGTCTTACGCTCGCTTTCGAGTGTTTCATATAGCAGCTTATTGGGCTTTATGCTGCGCGATCGTTTTGAT
CAAGCGATGGCTGATGCCCATGTTGGCCCGACGTTGGCGGTTTTCAATATTGCCTCAGCGGTTGGCGGCATTATTGGCGG
ACGCATTTCTGATCGAATTGGGCGCACAGTGGTGCTGCGTTCAAGTATTTTGAGCACAATTCCGCTTTTTATCGGCTTAG
TGCTATCATCGCCATTGAATTGGTGGTATTACCCCTTGACGGCACTGGTTGGGGCAATGGTGATGGCTAATATTCCGGTT
TCGATTGTCACAGCGCAGGAGTATGCACCGCAACATATTGCCACCGCCAGCGCCATGATGATGGGCTTTGCTTGGGGTAC
GTCGGGCGTGCTTTACCCCATCATTGGCAGCCTCGCCGACTGGACCTCGCCAACCTGGGCCATGATCGCCGCGATTGGCT
TGTTATTGCCAGCCTTCTTTATCACGGTACGGCTGCCCGAGCCTGAGCGCACAACGACGATAGGGTAG

Upstream 100 bases:

>100_bases
AAGGGGGTTTTGTTTAATCCAAAACCCTTCTCACAATTTCTGCATCTGCTATATACTTATCCTAATATGCGGGAAATTTC
ATAGGTGCTTTGGAGGCTTC

Downstream 100 bases:

>100_bases
TATTTGGGGATTGGTTATTGGGGGTTGGGGATCGGGAGCTTAGCTTATAACCGCGAAGAGCGCGAAGATTCACTTTATTA
TTGAACGCAGCGGCGCAGAG

Product: major facilitator transporter

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MATRTSGQAVALTGLSVMVMMTFSHAMNDMWTSLLAPLLPSIRDTYQVSIGQTGILVAILSFAGSMLQPLLGAVGDYIDR
RWLAAFGPVLTAIGLTLIGYVPNFFMLGALIMLGGLGSAIFHPAGAAYIAMGANPQQRGLFVSIFSAGGTVGMAFGPLIA
AQFDLVSLPYLLPVGIAVGVLTFLMIPSAKQNRSQPKTLRDYISVFQGPLRWLWFMSVLRSLSSVSYSSLLGFMLRDRFD
QAMADAHVGPTLAVFNIASAVGGIIGGRISDRIGRTVVLRSSILSTIPLFIGLVLSSPLNWWYYPLTALVGAMVMANIPV
SIVTAQEYAPQHIATASAMMMGFAWGTSGVLYPIIGSLADWTSPTWAMIAAIGLLLPAFFITVRLPEPERTTTIG

Sequences:

>Translated_395_residues
MATRTSGQAVALTGLSVMVMMTFSHAMNDMWTSLLAPLLPSIRDTYQVSIGQTGILVAILSFAGSMLQPLLGAVGDYIDR
RWLAAFGPVLTAIGLTLIGYVPNFFMLGALIMLGGLGSAIFHPAGAAYIAMGANPQQRGLFVSIFSAGGTVGMAFGPLIA
AQFDLVSLPYLLPVGIAVGVLTFLMIPSAKQNRSQPKTLRDYISVFQGPLRWLWFMSVLRSLSSVSYSSLLGFMLRDRFD
QAMADAHVGPTLAVFNIASAVGGIIGGRISDRIGRTVVLRSSILSTIPLFIGLVLSSPLNWWYYPLTALVGAMVMANIPV
SIVTAQEYAPQHIATASAMMMGFAWGTSGVLYPIIGSLADWTSPTWAMIAAIGLLLPAFFITVRLPEPERTTTIG
>Mature_394_residues
ATRTSGQAVALTGLSVMVMMTFSHAMNDMWTSLLAPLLPSIRDTYQVSIGQTGILVAILSFAGSMLQPLLGAVGDYIDRR
WLAAFGPVLTAIGLTLIGYVPNFFMLGALIMLGGLGSAIFHPAGAAYIAMGANPQQRGLFVSIFSAGGTVGMAFGPLIAA
QFDLVSLPYLLPVGIAVGVLTFLMIPSAKQNRSQPKTLRDYISVFQGPLRWLWFMSVLRSLSSVSYSSLLGFMLRDRFDQ
AMADAHVGPTLAVFNIASAVGGIIGGRISDRIGRTVVLRSSILSTIPLFIGLVLSSPLNWWYYPLTALVGAMVMANIPVS
IVTAQEYAPQHIATASAMMMGFAWGTSGVLYPIIGSLADWTSPTWAMIAAIGLLLPAFFITVRLPEPERTTTIG

Specific function: Confers The Resistance Against Fosmidomycin. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786686, Length=402, Percent_Identity=28.8557213930348, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42091; Mature: 41960

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure 
ATRTSGQAVALTGLSVMVMMTFSHAMNDMWTSLLAPLLPSIRDTYQVSIGQTGILVAIL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHH
SFAGSMLQPLLGAVGDYIDRRWLAAFGPVLTAIGLTLIGYVPNFFMLGALIMLGGLGSAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FHPAGAAYIAMGANPQQRGLFVSIFSAGGTVGMAFGPLIAAQFDLVSLPYLLPVGIAVGV
HCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTFLMIPSAKQNRSQPKTLRDYISVFQGPLRWLWFMSVLRSLSSVSYSSLLGFMLRDRFD
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAMADAHVGPTLAVFNIASAVGGIIGGRISDRIGRTVVLRSSILSTIPLFIGLVLSSPLN
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WWYYPLTALVGAMVMANIPVSIVTAQEYAPQHIATASAMMMGFAWGTSGVLYPIIGSLAD
HHHHHHHHHHHHHHHHCCCEEEEEHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
WTSPTWAMIAAIGLLLPAFFITVRLPEPERTTTIG
CCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]