Definition Herpetosiphon aurantiacus ATCC 23779 chromosome, complete genome.
Accession NC_009972
Length 6,346,587

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The map label for this gene is ucpA [C]

Identifier: 159899083

GI number: 159899083

Start: 3288082

End: 3288891

Strand: Direct

Name: ucpA [C]

Synonym: Haur_2564

Alternate gene names: 159899083

Gene position: 3288082-3288891 (Clockwise)

Preceding gene: 159899082

Following gene: 159899087

Centisome position: 51.81

GC content: 50.49

Gene sequence:

>810_bases
ATGATGCAAAAGATCGCTTTGATCACCGGGGCAAGCGGTGGAATTGGGCAAGCTATCACGCAAGGACTCGCCGAAGATGG
CTGGCAGACGGTTTTGATCGCCCGTGAGCCAACCAAACTCAATCAAACAGTCCAAGCTTTACAAAGCCAAGGCCATTGCA
GTGTTGGTTTTAGTGCTGATGTCCGCGACCCCGAAGCAGTCCAACAGGTAGTTGCAACCGTTATAGATGAGGTGGGAACA
CCAAATGCCATGATCAATCTTGCGGGAGTGCTTGGGCCATTTGGCCAATTCCATGATCTCGATCTGGATCAACTACGGTT
AATGTGCGATACGATCTGGTGGGGCACGCTCAATCTCTGTCATGCGGTTATTCCAGTAATGATTGAGCGTGGCGGTGGCT
CAATTATTAATATTGCTGGCTATGGCGCGGTTGAAGCATCGCCACGGCTGGCGGCGTATGGGGCAATCAAGGCCGCAATT
GTGCGCTTGAGCGAAACGCTGGCAATGGAATTGAAGCGCCAAAAGATTCGGGTTAATTGTATTGGGCCAGGGCTTGTTGC
CACCAAATTGAGCACCGAGCTTGAAAGCACACCCGAGGCCCAACGCTTTGCTGATGGGATGGTCAAAATGGCTCAAACCA
AAGGGGTTTCTGGGCAGGAGGCCGCCAAATTAGTGCGCTGGCTGCTTGCTGAGGATAATCCACTCACTGGACGGTTGATT
ACAGTCCACGATGCCTATGAACAATTAAGTTCGCAACTAGTGGAAATCAACCATAGCAGTCGTTATACTTTACGCCGTAT
TAATGATTAA

Upstream 100 bases:

>100_bases
TCAATAACTCTGGCGTTCGCCAATAACATCCTCGGATCATTCCTGTCACGTAGAACCTGATGAGCAATCGTCAGGTTCTC
GACGTTTAATAAAGGATTTA

Downstream 100 bases:

>100_bases
GTGAGCAGGCCGCTCAGTTGGCGTACTGAACGGCCTTTGGGTTTAATTACCAAGCACCATCAAGCCCATGCGGATACAAA
GCCACTTTGGCAGCCTCGCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MMQKIALITGASGGIGQAITQGLAEDGWQTVLIAREPTKLNQTVQALQSQGHCSVGFSADVRDPEAVQQVVATVIDEVGT
PNAMINLAGVLGPFGQFHDLDLDQLRLMCDTIWWGTLNLCHAVIPVMIERGGGSIINIAGYGAVEASPRLAAYGAIKAAI
VRLSETLAMELKRQKIRVNCIGPGLVATKLSTELESTPEAQRFADGMVKMAQTKGVSGQEAAKLVRWLLAEDNPLTGRLI
TVHDAYEQLSSQLVEINHSSRYTLRRIND

Sequences:

>Translated_269_residues
MMQKIALITGASGGIGQAITQGLAEDGWQTVLIAREPTKLNQTVQALQSQGHCSVGFSADVRDPEAVQQVVATVIDEVGT
PNAMINLAGVLGPFGQFHDLDLDQLRLMCDTIWWGTLNLCHAVIPVMIERGGGSIINIAGYGAVEASPRLAAYGAIKAAI
VRLSETLAMELKRQKIRVNCIGPGLVATKLSTELESTPEAQRFADGMVKMAQTKGVSGQEAAKLVRWLLAEDNPLTGRLI
TVHDAYEQLSSQLVEINHSSRYTLRRIND
>Mature_269_residues
MMQKIALITGASGGIGQAITQGLAEDGWQTVLIAREPTKLNQTVQALQSQGHCSVGFSADVRDPEAVQQVVATVIDEVGT
PNAMINLAGVLGPFGQFHDLDLDQLRLMCDTIWWGTLNLCHAVIPVMIERGGGSIINIAGYGAVEASPRLAAYGAIKAAI
VRLSETLAMELKRQKIRVNCIGPGLVATKLSTELESTPEAQRFADGMVKMAQTKGVSGQEAAKLVRWLLAEDNPLTGRLI
TVHDAYEQLSSQLVEINHSSRYTLRRIND

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=30.2788844621514, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=31.2169312169312, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI40254992, Length=194, Percent_Identity=30.4123711340206, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=28.6852589641434, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI19923817, Length=242, Percent_Identity=26.8595041322314, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=200, Percent_Identity=31, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=31, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI20149619, Length=225, Percent_Identity=26.2222222222222, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI10190704, Length=213, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI226371731, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87082100, Length=199, Percent_Identity=35.678391959799, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=30.6122448979592, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=29.1208791208791, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789208, Length=207, Percent_Identity=28.0193236714976, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=27.3858921161826, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=209, Percent_Identity=29.1866028708134, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=29, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790717, Length=190, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787905, Length=201, Percent_Identity=28.3582089552239, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=25.2918287937743, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=244, Percent_Identity=28.6885245901639, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17538486, Length=216, Percent_Identity=30.5555555555556, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=233, Percent_Identity=24.0343347639485, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=243, Percent_Identity=27.9835390946502, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=243, Percent_Identity=27.9835390946502, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=29.6116504854369, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=267, Percent_Identity=25.8426966292135, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=214, Percent_Identity=26.1682242990654, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=25.4166666666667, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=201, Percent_Identity=24.8756218905473, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212646214, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=214, Percent_Identity=28.5046728971963, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=25.9109311740891, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=236, Percent_Identity=27.5423728813559, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=215, Percent_Identity=24.6511627906977, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=209, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=25.5, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=29.6482412060301, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=195, Percent_Identity=23.5897435897436, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=32.6424870466321, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355319, Length=232, Percent_Identity=29.3103448275862, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=29.7872340425532, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24643142, Length=204, Percent_Identity=31.3725490196078, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=28.1914893617021, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24639444, Length=192, Percent_Identity=31.25, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=27.4611398963731, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI161076933, Length=272, Percent_Identity=24.6323529411765, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584748, Length=230, Percent_Identity=25.6521739130435, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28574402, Length=270, Percent_Identity=23.7037037037037, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24584744, Length=270, Percent_Identity=23.7037037037037, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=31.9796954314721, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=28.4615384615385, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281364494, Length=201, Percent_Identity=29.8507462686567, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28957; Mature: 28957

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MMQKIALITGASGGIGQAITQGLAEDGWQTVLIAREPTKLNQTVQALQSQGHCSVGFSAD
CCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCEEECCCCC
VRDPEAVQQVVATVIDEVGTPNAMINLAGVLGPFGQFHDLDLDQLRLMCDTIWWGTLNLC
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HAVIPVMIERGGGSIINIAGYGAVEASPRLAAYGAIKAAIVRLSETLAMELKRQKIRVNC
HHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
IGPGLVATKLSTELESTPEAQRFADGMVKMAQTKGVSGQEAAKLVRWLLAEDNPLTGRLI
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEE
TVHDAYEQLSSQLVEINHSSRYTLRRIND
EEHHHHHHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure
MMQKIALITGASGGIGQAITQGLAEDGWQTVLIAREPTKLNQTVQALQSQGHCSVGFSAD
CCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCEEECCCCC
VRDPEAVQQVVATVIDEVGTPNAMINLAGVLGPFGQFHDLDLDQLRLMCDTIWWGTLNLC
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HAVIPVMIERGGGSIINIAGYGAVEASPRLAAYGAIKAAIVRLSETLAMELKRQKIRVNC
HHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
IGPGLVATKLSTELESTPEAQRFADGMVKMAQTKGVSGQEAAKLVRWLLAEDNPLTGRLI
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEE
TVHDAYEQLSSQLVEINHSSRYTLRRIND
EEHHHHHHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]