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The map label for this gene is ruvA

Identifier: 159899035

GI number: 159899035

Start: 3213680

End: 3214273

Strand: Direct

Name: ruvA

Synonym: Haur_2516

Alternate gene names: 159899035

Gene position: 3213680-3214273 (Clockwise)

Preceding gene: 159899034

Following gene: 159899038

Centisome position: 50.64

GC content: 53.87

Gene sequence:

>594_bases
ATGATCGCATCGGTACGGGGTGTTGTGCAATTGATTGGTCAGGATCAAGTGGTAATTGACGTGCATGGTGTGGGTTTAGC
CATCGCCGTACCTCGCACCGTTTTAGCAACAATTGGCGCGATTGGCGATACCGCTCAGTTGTATACCCATTTGCATGTGC
GCGAAGATATGCTGGCCTTATTTGGCTTCAGCTCGCCAGCCCAACGTGCATTGTTTGAGCTATTACTGGGGGTCAGCGGA
ATTGGCCCCAAAGTTGCTTTAGCGCTGCTCTCGGCGGCCACCCCCGAAGAACTGCAACATGCGATCGCCCGCGAAGATAT
CACGATGCTCTCCAAAGTGCCAGGCATTGGCAAAAAAACCGCTGCCCGTTTGGTGCTCGAACTCAAAGGCAAATTTGGAG
TCGCTACAATCAGTCCGCAACTCAGCACCAACCCAGGCCTGCTAGCACTCAACACCGAACTGATCGATATTTTGACCAGC
CTTGGCTATAGCACTACCGAAGCCCAAGCAGCCCTGAATGCGCTCCCTGCCGATGCTCCCGCCGACACTGAAGAACGCCT
CCGCTTGGCCTTGCAATATTTTGGTGGGGTGTAA

Upstream 100 bases:

>100_bases
CCCATCAATGGCTGCTTTGGGTCAAACCAAGGCAGCCACTTTGAGCGCGACTCGCTGCAACCCTGTATAATAGACCCAAG
CTTAGCTAGGGAGATCAGGC

Downstream 100 bases:

>100_bases
TAACCCATCAGTCAGGCTCAAGCTAGAGTATTGGGCTATCCTATAACATAGGACTATCAAGAACGATTCTCGTTAGGATG
GCCGTAAGCTGACGCTGGCA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIASVRGVVQLIGQDQVVIDVHGVGLAIAVPRTVLATIGAIGDTAQLYTHLHVREDMLALFGFSSPAQRALFELLLGVSG
IGPKVALALLSAATPEELQHAIAREDITMLSKVPGIGKKTAARLVLELKGKFGVATISPQLSTNPGLLALNTELIDILTS
LGYSTTEAQAALNALPADAPADTEERLRLALQYFGGV

Sequences:

>Translated_197_residues
MIASVRGVVQLIGQDQVVIDVHGVGLAIAVPRTVLATIGAIGDTAQLYTHLHVREDMLALFGFSSPAQRALFELLLGVSG
IGPKVALALLSAATPEELQHAIAREDITMLSKVPGIGKKTAARLVLELKGKFGVATISPQLSTNPGLLALNTELIDILTS
LGYSTTEAQAALNALPADAPADTEERLRLALQYFGGV
>Mature_197_residues
MIASVRGVVQLIGQDQVVIDVHGVGLAIAVPRTVLATIGAIGDTAQLYTHLHVREDMLALFGFSSPAQRALFELLLGVSG
IGPKVALALLSAATPEELQHAIAREDITMLSKVPGIGKKTAARLVLELKGKFGVATISPQLSTNPGLLALNTELIDILTS
LGYSTTEAQAALNALPADAPADTEERLRLALQYFGGV

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=34.9753694581281, Blast_Score=113, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_HERA2 (A9AZL0)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001545282.1
- ProteinModelPortal:   A9AZL0
- SMR:   A9AZL0
- GeneID:   5734394
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_2516
- HOGENOM:   HBG635309
- OMA:   THLQVRE
- ProtClustDB:   PRK14604
- BioCyc:   HAUR316274:HAUR_2516-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like

EC number: =3.6.4.12

Molecular weight: Translated: 20583; Mature: 20583

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASVRGVVQLIGQDQVVIDVHGVGLAIAVPRTVLATIGAIGDTAQLYTHLHVREDMLAL
CCCHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FGFSSPAQRALFELLLGVSGIGPKVALALLSAATPEELQHAIAREDITMLSKVPGIGKKT
HCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AARLVLELKGKFGVATISPQLSTNPGLLALNTELIDILTSLGYSTTEAQAALNALPADAP
HHHHHHHHCCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
ADTEERLRLALQYFGGV
CCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIASVRGVVQLIGQDQVVIDVHGVGLAIAVPRTVLATIGAIGDTAQLYTHLHVREDMLAL
CCCHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FGFSSPAQRALFELLLGVSGIGPKVALALLSAATPEELQHAIAREDITMLSKVPGIGKKT
HCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AARLVLELKGKFGVATISPQLSTNPGLLALNTELIDILTSLGYSTTEAQAALNALPADAP
HHHHHHHHCCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
ADTEERLRLALQYFGGV
CCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA