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The map label for this gene is gpmA2 [H]

Identifier: 159898989

GI number: 159898989

Start: 3160306

End: 3160947

Strand: Reverse

Name: gpmA2 [H]

Synonym: Haur_2470

Alternate gene names: 159898989

Gene position: 3160947-3160306 (Counterclockwise)

Preceding gene: 159899004

Following gene: 159898987

Centisome position: 49.81

GC content: 49.22

Gene sequence:

>642_bases
ATGCGGTTAATTTTGGTGCGTCACGGTGAGAGTGAGTGGAATAAAATCGGTCGCTATCAAGGCCAAGAAGATGCGCCCTT
GAGCGAACTCGGCCAACAACAAGCCCAAGCCTTAGCCCAACGCCTCAAGCGCGAAAAGCTTGATGTGATTTACGCTAGCC
CCTTGCAACGAGCCAACAACACCGCTCGCGCAATTGCCGAATTTCACCCCGAAGTACCATTTATCGACGAGCCAGCCTTG
CTTGAAATTCATCATGGCGATTGGCAAGGGTTGTATAGCAACGATGTTAAGGCCCAATATGGCGCTGAATTACGCGAATG
GCAATATTTCCCAACTCGTTCGCAAATGCCCAACGGCGAAAGCTTCTCGAACATCCTCAAGCGCGTTATTGACTTTAAAG
AACGGGTTTTGAGCGAACGCCCCAACGAAACCGTGATTTTTTCAACTCACGATGTGGTTGTCAAAATTTTGGTTGCCGAT
GCACTTGGCATCAATATGGATCGGATCAATCGCTTGTGGATTACCAATGCCTCAATTAGCGTGATCGAATATGGCGAAGA
TTTGCCCTATTTGGTGAGCTTGAGCGAAGCTTGCCACCTTGGCAAATTGGCCACCGTGCGCGAAAACCAAACCGCCCTCT
AA

Upstream 100 bases:

>100_bases
CAACCATCTCAAACCAGCCAAAAGCTCAATGCAGATCTAGCTTGGAGGCTTCACTCATTTGCCTTCTGCCTTTTGCCTTT
TGACTTTACTTGGAGGCTTT

Downstream 100 bases:

>100_bases
AAAATGCCCTCACCCTCTAACTTCTCCACCAAAAGCCCCTCGCTCACCGCAGTGGGAGAGGGGTTGGGGTGAGGGCATGC
CGATCCTTGAAATCGAATTT

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM 2; PGAM 2; Phosphoglyceromutase 2; dPGM 2 [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRLILVRHGESEWNKIGRYQGQEDAPLSELGQQQAQALAQRLKREKLDVIYASPLQRANNTARAIAEFHPEVPFIDEPAL
LEIHHGDWQGLYSNDVKAQYGAELREWQYFPTRSQMPNGESFSNILKRVIDFKERVLSERPNETVIFSTHDVVVKILVAD
ALGINMDRINRLWITNASISVIEYGEDLPYLVSLSEACHLGKLATVRENQTAL

Sequences:

>Translated_213_residues
MRLILVRHGESEWNKIGRYQGQEDAPLSELGQQQAQALAQRLKREKLDVIYASPLQRANNTARAIAEFHPEVPFIDEPAL
LEIHHGDWQGLYSNDVKAQYGAELREWQYFPTRSQMPNGESFSNILKRVIDFKERVLSERPNETVIFSTHDVVVKILVAD
ALGINMDRINRLWITNASISVIEYGEDLPYLVSLSEACHLGKLATVRENQTAL
>Mature_213_residues
MRLILVRHGESEWNKIGRYQGQEDAPLSELGQQQAQALAQRLKREKLDVIYASPLQRANNTARAIAEFHPEVPFIDEPAL
LEIHHGDWQGLYSNDVKAQYGAELREWQYFPTRSQMPNGESFSNILKRVIDFKERVLSERPNETVIFSTHDVVVKILVAD
ALGINMDRINRLWITNASISVIEYGEDLPYLVSLSEACHLGKLATVRENQTAL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=245, Percent_Identity=26.9387755102041, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786857, Length=200, Percent_Identity=29.5, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790856, Length=188, Percent_Identity=29.7872340425532, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1786970, Length=218, Percent_Identity=28.8990825688073, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71993390, Length=175, Percent_Identity=30.8571428571429, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17510917, Length=175, Percent_Identity=30.8571428571429, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322697, Length=218, Percent_Identity=29.3577981651376, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28571815, Length=239, Percent_Identity=29.7071129707113, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571817, Length=239, Percent_Identity=29.7071129707113, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648979, Length=239, Percent_Identity=30.1255230125523, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646216, Length=106, Percent_Identity=40.5660377358491, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI85725270, Length=241, Percent_Identity=27.3858921161826, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85725272, Length=241, Percent_Identity=27.3858921161826, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650981, Length=241, Percent_Identity=27.3858921161826, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 24310; Mature: 24310

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLILVRHGESEWNKIGRYQGQEDAPLSELGQQQAQALAQRLKREKLDVIYASPLQRANN
CEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEECCHHHHCCH
TARAIAEFHPEVPFIDEPALLEIHHGDWQGLYSNDVKAQYGAELREWQYFPTRSQMPNGE
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCHHHHCCCCCCCCCCCCCH
SFSNILKRVIDFKERVLSERPNETVIFSTHDVVVKILVADALGINMDRINRLWITNASIS
HHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCEEEEECCCEE
VIEYGEDLPYLVSLSEACHLGKLATVRENQTAL
EEECCCCCCHHHHHHHHHCCCCHHEECCCCCCC
>Mature Secondary Structure
MRLILVRHGESEWNKIGRYQGQEDAPLSELGQQQAQALAQRLKREKLDVIYASPLQRANN
CEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEECCHHHHCCH
TARAIAEFHPEVPFIDEPALLEIHHGDWQGLYSNDVKAQYGAELREWQYFPTRSQMPNGE
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCHHHHCCCCCCCCCCCCCH
SFSNILKRVIDFKERVLSERPNETVIFSTHDVVVKILVADALGINMDRINRLWITNASIS
HHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCEEEEECCCEE
VIEYGEDLPYLVSLSEACHLGKLATVRENQTAL
EEECCCCCCHHHHHHHHHCCCCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]