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The map label for this gene is muT4 [H]

Identifier: 159898949

GI number: 159898949

Start: 3112554

End: 3112997

Strand: Direct

Name: muT4 [H]

Synonym: Haur_2428

Alternate gene names: 159898949

Gene position: 3112554-3112997 (Clockwise)

Preceding gene: 159898945

Following gene: 159898952

Centisome position: 49.04

GC content: 49.77

Gene sequence:

>444_bases
ATGAGCCAGATTCGCAAAAGTCGTATTGCTTATTCAGCCGGTGGTGTTTGCTATCGCTGGATGGATGAAGTGCCTGAGGT
AGTGCTGATTGCGACCCATAACAGTACACGCTGGGGTTTGCCAAAAGGCCATCGTGAAGGTCGCGAAACCTTTGCCCAAG
CAGCCCGCCGTGAAATAAACGAAGAAACTGGCTTACGCGGCGAAATCGTTTGCTCGCTTTCGGCAATTCAATATTGGTTT
CGGGTTGAGAGCCATTTTGTGCATAAATGGGTCGAGTTTTTTCTGTTTCGCTGTACTGGCGGCTGTCTCAAGCCACAGCT
TTCGGAAATCGACGATGCCCAGTGGTTTTTGTTACCCGATGCACTAGAGCAAATTAGCTTTCCGCGTGAGCGAAGCGTGC
TCGAGGTGGTTAACACGATCTGGCGATCGAATCGTTTAATCTAG

Upstream 100 bases:

>100_bases
AAGCAAAATCGAATACTTGTTCAGCAGCATTACGCTTGCTGAACGCCAGATGCGGGCGGCCCTAGGTCGGCTCGCATCTT
GATACCTGATGGAGGCATGA

Downstream 100 bases:

>100_bases
TTTGGGCAGCGGCTTGAGCCACATAACGCTCGGCAACAAGCGACCCATTTTTTGGGCTAAAGGCAAGCCAACAACGCTAA
CCGTGGCTAGCCAGATAACC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSQIRKSRIAYSAGGVCYRWMDEVPEVVLIATHNSTRWGLPKGHREGRETFAQAARREINEETGLRGEIVCSLSAIQYWF
RVESHFVHKWVEFFLFRCTGGCLKPQLSEIDDAQWFLLPDALEQISFPRERSVLEVVNTIWRSNRLI

Sequences:

>Translated_147_residues
MSQIRKSRIAYSAGGVCYRWMDEVPEVVLIATHNSTRWGLPKGHREGRETFAQAARREINEETGLRGEIVCSLSAIQYWF
RVESHFVHKWVEFFLFRCTGGCLKPQLSEIDDAQWFLLPDALEQISFPRERSVLEVVNTIWRSNRLI
>Mature_146_residues
SQIRKSRIAYSAGGVCYRWMDEVPEVVLIATHNSTRWGLPKGHREGRETFAQAARREINEETGLRGEIVCSLSAIQYWFR
VESHFVHKWVEFFLFRCTGGCLKPQLSEIDDAQWFLLPDALEQISFPRERSVLEVVNTIWRSNRLI

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 17158; Mature: 17027

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIRKSRIAYSAGGVCYRWMDEVPEVVLIATHNSTRWGLPKGHREGRETFAQAARREIN
CCCHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
EETGLRGEIVCSLSAIQYWFRVESHFVHKWVEFFLFRCTGGCLKPQLSEIDDAQWFLLPD
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCEEECHH
ALEQISFPRERSVLEVVNTIWRSNRLI
HHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQIRKSRIAYSAGGVCYRWMDEVPEVVLIATHNSTRWGLPKGHREGRETFAQAARREIN
CCHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
EETGLRGEIVCSLSAIQYWFRVESHFVHKWVEFFLFRCTGGCLKPQLSEIDDAQWFLLPD
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCEEECHH
ALEQISFPRERSVLEVVNTIWRSNRLI
HHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]