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The map label for this gene is mtnA [H]

Identifier: 159898870

GI number: 159898870

Start: 2997620

End: 2998696

Strand: Direct

Name: mtnA [H]

Synonym: Haur_2349

Alternate gene names: 159898870

Gene position: 2997620-2998696 (Clockwise)

Preceding gene: 159898869

Following gene: 159898871

Centisome position: 47.23

GC content: 52.46

Gene sequence:

>1077_bases
ATGCAACCAATGGCTGACGTACTTAAAACTGTTTGGTGGGATGAAGTTCCCTGTTTGATCGACCAACGTCTTTTGCCAGC
AACGCTGGATATTGTACGTTGTGAGGATTTAAATAGCGTGATCGAGGCGATTCGCTCAATGCAAGTGCGAGGCGCTCCAG
CAATCGGCATCACGGCAGCCTATGGCATGGCCTTGGCCGCCCAACGCAGCACCGCCCAAACCAGCAGTAAATTACTCGAA
AAACTAGCTAAAGCCAAAGCGCTGCTTGATGCCACGCGGCCTACGGCGATCAATCTAGCTTGGGCCACTCAGCGCATGCT
TGACGTAGCCCAAGCCAATCACACACTTGAGGTTGATCAATTACGTCAGCGTTTATTGGCTGAAGCCGAGGCCATTCGCG
ACCAAGACGAGGCTATGTGTCGGGCAATCGGCCAGCATGGCAAAGTACTCTTGGCCCAATCGCGCAATGTGCTGACCCAC
TGCAACGCTGGTGGTTTAGCCACGGCAGCCTATGGCACGGCGCTCGCACCAATTCGCGCAGTCCATGAAGATGGGCAGCC
AATTCATGTTTGGGTCGATGAAACGCGGCCATTTTTGCAGGGCGCACGACTCACCGCGTGGGAATTGCAACAGGCAGGCA
TCGATTTAACCTTAATTACCGATAACATGGCTGCTTATTTTATGCAGCAAGGCCAGGTTGATTGTATTATCGTTGGCTCG
GATCGGATTGCGGCAAATGGCGATGTTGCCAATAAAATCGGCACTTATGGGCTGGCAGTGTTAGCCAAAGCGCACAATAT
TCCACTGTATGTTGCTGCGCCAACATCGACCATTGATTTGCAGACCGCCGATGGCGCGGCAATTCCAATCGAACAACGTT
CAACCCAAGAAGTAACCCATATTGGGCAACAGGCAATTGCGGCAGCAGGCATTAAGGTGGCGCATCCGGCTTTTGATGTG
ACTCCGGCGCATTTGGTAACAGCAATTATTACCGAACAAGGCATTGCCTACCCGCCCTTTGCTGAACAATTACAAACCAT
GGTTGAGGCTGCCAATGCCGCCAACGCTGGCAAGTGA

Upstream 100 bases:

>100_bases
CCCGGCAACCCCATTATTTGGAAGGTGCCAAATCCTGCAGGTTCGGCCTGATAGATGAGTTTGAGCATGCGGGCCTCTCT
CTGAGAGGTTTTTTTGTGTA

Downstream 100 bases:

>100_bases
GTTTCGCTGTCAAGCGATCGCACCATTTGATCTGCCCTATACCAATCAGGCAAGTGCATGGGCGGCCCAAATGCGTTGGA
CTCAGGGCTATCCGATTGCC

Product: aIF-2BI family translation initiation factor

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MQPMADVLKTVWWDEVPCLIDQRLLPATLDIVRCEDLNSVIEAIRSMQVRGAPAIGITAAYGMALAAQRSTAQTSSKLLE
KLAKAKALLDATRPTAINLAWATQRMLDVAQANHTLEVDQLRQRLLAEAEAIRDQDEAMCRAIGQHGKVLLAQSRNVLTH
CNAGGLATAAYGTALAPIRAVHEDGQPIHVWVDETRPFLQGARLTAWELQQAGIDLTLITDNMAAYFMQQGQVDCIIVGS
DRIAANGDVANKIGTYGLAVLAKAHNIPLYVAAPTSTIDLQTADGAAIPIEQRSTQEVTHIGQQAIAAAGIKVAHPAFDV
TPAHLVTAIITEQGIAYPPFAEQLQTMVEAANAANAGK

Sequences:

>Translated_358_residues
MQPMADVLKTVWWDEVPCLIDQRLLPATLDIVRCEDLNSVIEAIRSMQVRGAPAIGITAAYGMALAAQRSTAQTSSKLLE
KLAKAKALLDATRPTAINLAWATQRMLDVAQANHTLEVDQLRQRLLAEAEAIRDQDEAMCRAIGQHGKVLLAQSRNVLTH
CNAGGLATAAYGTALAPIRAVHEDGQPIHVWVDETRPFLQGARLTAWELQQAGIDLTLITDNMAAYFMQQGQVDCIIVGS
DRIAANGDVANKIGTYGLAVLAKAHNIPLYVAAPTSTIDLQTADGAAIPIEQRSTQEVTHIGQQAIAAAGIKVAHPAFDV
TPAHLVTAIITEQGIAYPPFAEQLQTMVEAANAANAGK
>Mature_358_residues
MQPMADVLKTVWWDEVPCLIDQRLLPATLDIVRCEDLNSVIEAIRSMQVRGAPAIGITAAYGMALAAQRSTAQTSSKLLE
KLAKAKALLDATRPTAINLAWATQRMLDVAQANHTLEVDQLRQRLLAEAEAIRDQDEAMCRAIGQHGKVLLAQSRNVLTH
CNAGGLATAAYGTALAPIRAVHEDGQPIHVWVDETRPFLQGARLTAWELQQAGIDLTLITDNMAAYFMQQGQVDCIIVGS
DRIAANGDVANKIGTYGLAVLAKAHNIPLYVAAPTSTIDLQTADGAAIPIEQRSTQEVTHIGQQAIAAAGIKVAHPAFDV
TPAHLVTAIITEQGIAYPPFAEQLQTMVEAANAANAGK

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=340, Percent_Identity=43.2352941176471, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI23943880, Length=331, Percent_Identity=38.9728096676737, Blast_Score=185, Evalue=4e-47,
Organism=Homo sapiens, GI4503503, Length=231, Percent_Identity=27.7056277056277, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7657058, Length=167, Percent_Identity=33.5329341317365, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI78000158, Length=174, Percent_Identity=28.1609195402299, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI78000156, Length=174, Percent_Identity=28.1609195402299, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI187607323, Length=174, Percent_Identity=28.1609195402299, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17557462, Length=333, Percent_Identity=38.1381381381381, Blast_Score=220, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI17557123, Length=280, Percent_Identity=26.0714285714286, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325375, Length=379, Percent_Identity=33.7730870712401, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21357667, Length=350, Percent_Identity=40.8571428571429, Blast_Score=254, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24651647, Length=350, Percent_Identity=40.8571428571429, Blast_Score=254, Evalue=5e-68,
Organism=Drosophila melanogaster, GI21358605, Length=221, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38266; Mature: 38266

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPMADVLKTVWWDEVPCLIDQRLLPATLDIVRCEDLNSVIEAIRSMQVRGAPAIGITAA
CCCHHHHHHHHHHCCCCHHHHCCCCHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCHHHHH
YGMALAAQRSTAQTSSKLLEKLAKAKALLDATRPTAINLAWATQRMLDVAQANHTLEVDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCCHHH
LRQRLLAEAEAIRDQDEAMCRAIGQHGKVLLAQSRNVLTHCNAGGLATAAYGTALAPIRA
HHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHH
VHEDGQPIHVWVDETRPFLQGARLTAWELQQAGIDLTLITDNMAAYFMQQGQVDCIIVGS
HHCCCCEEEEEECCCCHHHCCCCCHHHHHHHCCCEEEEEECHHHHHHHHCCCEEEEEECC
DRIAANGDVANKIGTYGLAVLAKAHNIPLYVAAPTSTIDLQTADGAAIPIEQRSTQEVTH
CCEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHH
IGQQAIAAAGIKVAHPAFDVTPAHLVTAIITEQGIAYPPFAEQLQTMVEAANAANAGK
HHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQPMADVLKTVWWDEVPCLIDQRLLPATLDIVRCEDLNSVIEAIRSMQVRGAPAIGITAA
CCCHHHHHHHHHHCCCCHHHHCCCCHHHHHHEEHHHHHHHHHHHHHHHCCCCCCCHHHHH
YGMALAAQRSTAQTSSKLLEKLAKAKALLDATRPTAINLAWATQRMLDVAQANHTLEVDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCCHHH
LRQRLLAEAEAIRDQDEAMCRAIGQHGKVLLAQSRNVLTHCNAGGLATAAYGTALAPIRA
HHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHH
VHEDGQPIHVWVDETRPFLQGARLTAWELQQAGIDLTLITDNMAAYFMQQGQVDCIIVGS
HHCCCCEEEEEECCCCHHHCCCCCHHHHHHHCCCEEEEEECHHHHHHHHCCCEEEEEECC
DRIAANGDVANKIGTYGLAVLAKAHNIPLYVAAPTSTIDLQTADGAAIPIEQRSTQEVTH
CCEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHH
IGQQAIAAAGIKVAHPAFDVTPAHLVTAIITEQGIAYPPFAEQLQTMVEAANAANAGK
HHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA