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The map label for this gene is regX3 [H]

Identifier: 159898827

GI number: 159898827

Start: 2945496

End: 2946173

Strand: Direct

Name: regX3 [H]

Synonym: Haur_2306

Alternate gene names: 159898827

Gene position: 2945496-2946173 (Clockwise)

Preceding gene: 159898826

Following gene: 159898828

Centisome position: 46.41

GC content: 49.12

Gene sequence:

>678_bases
ATGGCCGCGACAATCATCATTATTGAAGATGAAGAACGGATTGCCCATTGGATGCAGTTGTATCTTGAGCAAGCGGGCTT
TACAACCTATTTGGCCAGCGACGGCCTAGCAGGCTTGGCTTTGGTGCAGCAACACCAGCCAAGTTTAGTCGTTTTAGATC
TGATGTTGCCCAAATTGGATGGCTTAGCGGTCTTCAAGACGATTCGCCAAACTAGCAATACGCCAATTATTATGGTAACT
GCGCGTAGCAGTGATGAAGAACGAATCCATGGCTTGGAGCTTGGCGCTGATGATTATGTTGGCAAGCCCTTCAATGCTCG
CGAATTGGTGGCGCGAGTGCGGGCGGTTTTGCGGCGCAGCCAGCCAATTCAAGCTAGCCAAATGTTGAAACGCGGCCCGA
TCGAATTGGATTTGGAGCAACATTCATGCACCGTCAATCAGCAACCTGTCGAATTGAGCAAAATTCAATTGGCCTTGCTG
GCGACATTTATGCGCCATCCCAACCAAATTCTCAGCCGCGAACAGTTGCTTGAAGCCGTATTTGCTGGCGATTATGCTGG
CTTTGATCGTTCGCTTGATGCGCATATCGCGCGTTTGCGCCAACGGATCGAACATGATCGCACCAATCCACAGTATATTG
TGACGGTGTATGGACTTGGCTATAAATTTGTTGATTAG

Upstream 100 bases:

>100_bases
ACCAGTCGCACCAACCACCGATTCAAGTCGTTAGATCGCATGGCTGGTTGCAACATTCACCACGCCTGCAACCAGCCTTA
ATCCACACCAAGGAAGCAGC

Downstream 100 bases:

>100_bases
GTAGGGTGTTATGGGCAAATCGTTACGCTGGAAATTAGGGGCAGCATTTGGCTTGGTGATTAGCGCAACCCTCTTGTTGA
GCGGGCTAAGCGCATATTTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAATIIIIEDEERIAHWMQLYLEQAGFTTYLASDGLAGLALVQQHQPSLVVLDLMLPKLDGLAVFKTIRQTSNTPIIMVT
ARSSDEERIHGLELGADDYVGKPFNARELVARVRAVLRRSQPIQASQMLKRGPIELDLEQHSCTVNQQPVELSKIQLALL
ATFMRHPNQILSREQLLEAVFAGDYAGFDRSLDAHIARLRQRIEHDRTNPQYIVTVYGLGYKFVD

Sequences:

>Translated_225_residues
MAATIIIIEDEERIAHWMQLYLEQAGFTTYLASDGLAGLALVQQHQPSLVVLDLMLPKLDGLAVFKTIRQTSNTPIIMVT
ARSSDEERIHGLELGADDYVGKPFNARELVARVRAVLRRSQPIQASQMLKRGPIELDLEQHSCTVNQQPVELSKIQLALL
ATFMRHPNQILSREQLLEAVFAGDYAGFDRSLDAHIARLRQRIEHDRTNPQYIVTVYGLGYKFVD
>Mature_224_residues
AATIIIIEDEERIAHWMQLYLEQAGFTTYLASDGLAGLALVQQHQPSLVVLDLMLPKLDGLAVFKTIRQTSNTPIIMVTA
RSSDEERIHGLELGADDYVGKPFNARELVARVRAVLRRSQPIQASQMLKRGPIELDLEQHSCTVNQQPVELSKIQLALLA
TFMRHPNQILSREQLLEAVFAGDYAGFDRSLDAHIARLRQRIEHDRTNPQYIVTVYGLGYKFVD

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=39.647577092511, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=38.8646288209607, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=37.7272727272727, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=37.0044052863436, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=218, Percent_Identity=33.9449541284404, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.1818181818182, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=32.8828828828829, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=33.7777777777778, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=36.2445414847162, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=30.2631578947368, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=33.0275229357798, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=28.9592760180996, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=29.1845493562232, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.9622641509434, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=31, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=157, Percent_Identity=26.1146496815287, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25405; Mature: 25273

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATIIIIEDEERIAHWMQLYLEQAGFTTYLASDGLAGLALVQQHQPSLVVLDLMLPKLD
CCEEEEEEECHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEHHCCCC
GLAVFKTIRQTSNTPIIMVTARSSDEERIHGLELGADDYVGKPFNARELVARVRAVLRRS
HHHHHHHHHHCCCCCEEEEEECCCCCHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHHCC
QPIQASQMLKRGPIELDLEQHSCTVNQQPVELSKIQLALLATFMRHPNQILSREQLLEAV
CCCCHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FAGDYAGFDRSLDAHIARLRQRIEHDRTNPQYIVTVYGLGYKFVD
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEECC
>Mature Secondary Structure 
AATIIIIEDEERIAHWMQLYLEQAGFTTYLASDGLAGLALVQQHQPSLVVLDLMLPKLD
CEEEEEEECHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEHHCCCC
GLAVFKTIRQTSNTPIIMVTARSSDEERIHGLELGADDYVGKPFNARELVARVRAVLRRS
HHHHHHHHHHCCCCCEEEEEECCCCCHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHHCC
QPIQASQMLKRGPIELDLEQHSCTVNQQPVELSKIQLALLATFMRHPNQILSREQLLEAV
CCCCHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FAGDYAGFDRSLDAHIARLRQRIEHDRTNPQYIVTVYGLGYKFVD
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA