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The map label for this gene is rsbRA [H]

Identifier: 159898727

GI number: 159898727

Start: 2803288

End: 2804391

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_2206

Alternate gene names: 159898727

Gene position: 2803288-2804391 (Clockwise)

Preceding gene: 159898726

Following gene: 159898728

Centisome position: 44.17

GC content: 50.0

Gene sequence:

>1104_bases
ATGCGTTTTAAGGCTTTACTCGCAGGGCTTTTTCGAATCAACCACGCCGACGCAAATATTCGGCGGCGTGGTAAGGCCAT
CGTTGGGATTACCTTCTTTTTGGTTTGCTGTATCACATTAATTGGTATTTTCAGCATTTTTGCAACTGGCTGGCGCGAAA
CTGCCTTACTCACCAGCCCATTTGGGTTGCTTGGGCTAGCAGCAATTTGGCTGGCTCGCCGTGGAATGGCCAATCGCGCC
GCCGGATTATTGATTACCGCCGCACTCATGGCCCTGATCGCAGCGCCAGTATTGGCCAATCGGGTAGCTTTTACGCCATT
TTTCTTTCTCTTACCAATTCTGATGGCCTTTATCACGCTTTCGCCGCGCGGTTTACTGTTCGCCAGTGGCACGAGTTTGG
CTGCGTTAGGTTTGCTCGCGCTATTAACTCAAAATATTCCGCAAACATTGCCGCAAAATAGCGAAGTATTCGGCTTGGCC
AGCACCCTCTTGTTGATGATTATTGGTTTGGGCTATGTTGGCTCACGCACTACCCATCAAGCCATCCACGCAATGAATCT
AGCTCAGCAGCGGAGCCGCGAATTAACTAAAACACTGCAAGATGAGCGTGATCAACTCAGCCAACGAGTTGACGAAAGCA
CGGCAGAATTACGCCAAAGTTTGGCAAATTCGGAACAGCTGATCGCTGAACAAGCCCGTTTGTTGAACGAGAATGATCAA
CAACGTTCAACCATTCGTTCCTTGAGTTTGCCAATCTTGCCATTGCATCAACACATGTTACTTGCCCCACTGATTGGCAC
GTTTGATCAGCAACGTTTACACGATGTTCAAGCGCAGCTTTTACAGGCGGTTGAGACCTATCAAGCCAAAATTCTGCTCT
TAGATTTAACTGGAGTTGCGGTGCTTGATCAGGCTGGGGCAGCCATGCTTCAGCAGATTGTCCATGCCAGCAGCTTGCTT
GGGGCAGCCGTTGCATTCATCGGCGTGCGGCCTGAAGCAGCCCAAGCCATTGTAAGTATGGGCCACGAGCTTGGCAATGT
ACGGGTTTTTCGCGATCTGCAAGCGGCAATTCAGCAGCATAGTCGGCTGTTATTCGATAGCTAG

Upstream 100 bases:

>100_bases
CATTGATTTAGCAGATCAAGGCAAACCATATCGTTTAATTTTGGCAACGATTGCTGAATAATGATCACCAAAGGCCATTT
TAGCTGGATATCATAGCACT

Downstream 100 bases:

>100_bases
CCAGCCTTCGGGTATACTAGCAATTGTTTTGCAGGCTGCGTTAGCGCAACCGATAGAGACTTGCACGATGGATGATCGGC
CAATCTTCCCTGAATGGATC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MRFKALLAGLFRINHADANIRRRGKAIVGITFFLVCCITLIGIFSIFATGWRETALLTSPFGLLGLAAIWLARRGMANRA
AGLLITAALMALIAAPVLANRVAFTPFFFLLPILMAFITLSPRGLLFASGTSLAALGLLALLTQNIPQTLPQNSEVFGLA
STLLLMIIGLGYVGSRTTHQAIHAMNLAQQRSRELTKTLQDERDQLSQRVDESTAELRQSLANSEQLIAEQARLLNENDQ
QRSTIRSLSLPILPLHQHMLLAPLIGTFDQQRLHDVQAQLLQAVETYQAKILLLDLTGVAVLDQAGAAMLQQIVHASSLL
GAAVAFIGVRPEAAQAIVSMGHELGNVRVFRDLQAAIQQHSRLLFDS

Sequences:

>Translated_367_residues
MRFKALLAGLFRINHADANIRRRGKAIVGITFFLVCCITLIGIFSIFATGWRETALLTSPFGLLGLAAIWLARRGMANRA
AGLLITAALMALIAAPVLANRVAFTPFFFLLPILMAFITLSPRGLLFASGTSLAALGLLALLTQNIPQTLPQNSEVFGLA
STLLLMIIGLGYVGSRTTHQAIHAMNLAQQRSRELTKTLQDERDQLSQRVDESTAELRQSLANSEQLIAEQARLLNENDQ
QRSTIRSLSLPILPLHQHMLLAPLIGTFDQQRLHDVQAQLLQAVETYQAKILLLDLTGVAVLDQAGAAMLQQIVHASSLL
GAAVAFIGVRPEAAQAIVSMGHELGNVRVFRDLQAAIQQHSRLLFDS
>Mature_367_residues
MRFKALLAGLFRINHADANIRRRGKAIVGITFFLVCCITLIGIFSIFATGWRETALLTSPFGLLGLAAIWLARRGMANRA
AGLLITAALMALIAAPVLANRVAFTPFFFLLPILMAFITLSPRGLLFASGTSLAALGLLALLTQNIPQTLPQNSEVFGLA
STLLLMIIGLGYVGSRTTHQAIHAMNLAQQRSRELTKTLQDERDQLSQRVDESTAELRQSLANSEQLIAEQARLLNENDQ
QRSTIRSLSLPILPLHQHMLLAPLIGTFDQQRLHDVQAQLLQAVETYQAKILLLDLTGVAVLDQAGAAMLQQIVHASSLL
GAAVAFIGVRPEAAQAIVSMGHELGNVRVFRDLQAAIQQHSRLLFDS

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39933; Mature: 39933

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFKALLAGLFRINHADANIRRRGKAIVGITFFLVCCITLIGIFSIFATGWRETALLTSP
CCHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
FGLLGLAAIWLARRGMANRAAGLLITAALMALIAAPVLANRVAFTPFFFLLPILMAFITL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPRGLLFASGTSLAALGLLALLTQNIPQTLPQNSEVFGLASTLLLMIIGLGYVGSRTTHQ
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
AIHAMNLAQQRSRELTKTLQDERDQLSQRVDESTAELRQSLANSEQLIAEQARLLNENDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QRSTIRSLSLPILPLHQHMLLAPLIGTFDQQRLHDVQAQLLQAVETYQAKILLLDLTGVA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHH
VLDQAGAAMLQQIVHASSLLGAAVAFIGVRPEAAQAIVSMGHELGNVRVFRDLQAAIQQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SRLLFDS
HHHHCCC
>Mature Secondary Structure
MRFKALLAGLFRINHADANIRRRGKAIVGITFFLVCCITLIGIFSIFATGWRETALLTSP
CCHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
FGLLGLAAIWLARRGMANRAAGLLITAALMALIAAPVLANRVAFTPFFFLLPILMAFITL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPRGLLFASGTSLAALGLLALLTQNIPQTLPQNSEVFGLASTLLLMIIGLGYVGSRTTHQ
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
AIHAMNLAQQRSRELTKTLQDERDQLSQRVDESTAELRQSLANSEQLIAEQARLLNENDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QRSTIRSLSLPILPLHQHMLLAPLIGTFDQQRLHDVQAQLLQAVETYQAKILLLDLTGVA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHH
VLDQAGAAMLQQIVHASSLLGAAVAFIGVRPEAAQAIVSMGHELGNVRVFRDLQAAIQQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SRLLFDS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]