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The map label for this gene is pksS [H]

Identifier: 159898490

GI number: 159898490

Start: 2402538

End: 2403773

Strand: Direct

Name: pksS [H]

Synonym: Haur_1966

Alternate gene names: 159898490

Gene position: 2402538-2403773 (Clockwise)

Preceding gene: 159898489

Following gene: 159898492

Centisome position: 37.86

GC content: 49.76

Gene sequence:

>1236_bases
ATGAGTAGTGTATCGCGTGAAACCAAGCCCACTCAACCAGTCTTGAATTTGACTGATCGCCAATTCAAGGCTGATCCGTT
TAGTATTTATGCTCAGTTACGCCGTGATAATCCAGTTGCTAAAGCTAAACTTGGCTCGCTGCCGACATGGATTGTTACCC
GCTACGATGATGTCGTTGAAATTTTGAAAAACGATCGGGTCTTTGTCAAAAACTATAAGAATGCCCAATCGTTGGAGCAA
CAACGCAAACGCCCATGGATGCCCGCATCGCTTCGAGCGCTCGAAAGCAATATGCTCGATCAAGATAACCCTGACCATCT
GCGCTTACGTTCATTGGTCCACAAAGCTTTTACCCCTCAGCGCATGGAAGAAATGCGGCCACGCATTCAGTCAATTGCTG
AATCATTATTAATCAGCAGCCAACAACGTGGTCGCGGCGATTTGATTGCCGATTTTGCCTTGCCCCTGCCTTTGACCGTG
ATCGTCGAATTGCTTGGCATTCCAACTGAGGATCGCCAAAAATTTCATCGTTGGGCCAAATATGTACTGAACAGCCCAAC
CATGCTGAATATGCTATTGGCAATTCCGGCAATTATGGCTCAGATGAAATATCTCAAACAACTTTTTGCCAAGCGGCGCA
GCAACCCCCAAGACGATTTGCTGACGGCGTTGGTGCAAGCTGAGGCCGATGGTGATCGTTTCAGTGAAGATGAATTAGTC
GCCATGGTCTTTTTGCTGATGCTCGCAGGCCACGAAACCACGGTCAATCTGATTTCATCGGGAACCCTAGCGTTATTGCA
GCATCCTGAGCAGTTGGCCTTGTTGCGACGTTCGCCAGAGTTGATCAAATCGGCAGTTGAGGAATTGGTGCGGTTTACTG
CGCCAGTTGAAACCGCGACCGAGCGCTACGCTGCTGAAGATGTGATTATTGCCGACACCAAGATTGCCAAAGGCGAAATG
GTTTTGGTCGCGCTGGCCTCAGCCAATCGGGATGAACGCCAATTTACTAACCCTGATCAACTCGACATAACCCGAGAAAA
GAATCGCCATGTTGGTTTTGGTTTGGGCATTCACTATTGCTTAGGTGCGCCTTTAGCCCGCATGGAAGCCCAAATTGGCC
TGCAATTATTGACTGATCTGCGCCCAAACTTGCGCTTAGCCGTGCCCGCTGAGCAGTTGCGTTGGCGTTCGACCGCAGTT
GTGCGCGGCCTCGAAGCCTTGCCTGTGGAGTGGTAA

Upstream 100 bases:

>100_bases
TTGCGCATGTTGGGCGATGAGGTTGCCATCAATCAATGGCCTGAATTAGCTCGTACCACCATCAATTTGGTGTTGTATGG
CATTCTCCAGGAGCCGCCAC

Downstream 100 bases:

>100_bases
GTTCTGGTTGGGGTATGGCGAGCATAATGGAATGGCTCGCCATACCCTTATTATAGAATTTGCCGATTAAATTCAATTCA
ATGTCTCAAAACTTAGCGGT

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSSVSRETKPTQPVLNLTDRQFKADPFSIYAQLRRDNPVAKAKLGSLPTWIVTRYDDVVEILKNDRVFVKNYKNAQSLEQ
QRKRPWMPASLRALESNMLDQDNPDHLRLRSLVHKAFTPQRMEEMRPRIQSIAESLLISSQQRGRGDLIADFALPLPLTV
IVELLGIPTEDRQKFHRWAKYVLNSPTMLNMLLAIPAIMAQMKYLKQLFAKRRSNPQDDLLTALVQAEADGDRFSEDELV
AMVFLLMLAGHETTVNLISSGTLALLQHPEQLALLRRSPELIKSAVEELVRFTAPVETATERYAAEDVIIADTKIAKGEM
VLVALASANRDERQFTNPDQLDITREKNRHVGFGLGIHYCLGAPLARMEAQIGLQLLTDLRPNLRLAVPAEQLRWRSTAV
VRGLEALPVEW

Sequences:

>Translated_411_residues
MSSVSRETKPTQPVLNLTDRQFKADPFSIYAQLRRDNPVAKAKLGSLPTWIVTRYDDVVEILKNDRVFVKNYKNAQSLEQ
QRKRPWMPASLRALESNMLDQDNPDHLRLRSLVHKAFTPQRMEEMRPRIQSIAESLLISSQQRGRGDLIADFALPLPLTV
IVELLGIPTEDRQKFHRWAKYVLNSPTMLNMLLAIPAIMAQMKYLKQLFAKRRSNPQDDLLTALVQAEADGDRFSEDELV
AMVFLLMLAGHETTVNLISSGTLALLQHPEQLALLRRSPELIKSAVEELVRFTAPVETATERYAAEDVIIADTKIAKGEM
VLVALASANRDERQFTNPDQLDITREKNRHVGFGLGIHYCLGAPLARMEAQIGLQLLTDLRPNLRLAVPAEQLRWRSTAV
VRGLEALPVEW
>Mature_410_residues
SSVSRETKPTQPVLNLTDRQFKADPFSIYAQLRRDNPVAKAKLGSLPTWIVTRYDDVVEILKNDRVFVKNYKNAQSLEQQ
RKRPWMPASLRALESNMLDQDNPDHLRLRSLVHKAFTPQRMEEMRPRIQSIAESLLISSQQRGRGDLIADFALPLPLTVI
VELLGIPTEDRQKFHRWAKYVLNSPTMLNMLLAIPAIMAQMKYLKQLFAKRRSNPQDDLLTALVQAEADGDRFSEDELVA
MVFLLMLAGHETTVNLISSGTLALLQHPEQLALLRRSPELIKSAVEELVRFTAPVETATERYAAEDVIIADTKIAKGEMV
LVALASANRDERQFTNPDQLDITREKNRHVGFGLGIHYCLGAPLARMEAQIGLQLLTDLRPNLRLAVPAEQLRWRSTAVV
RGLEALPVEW

Specific function: Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI98991773, Length=229, Percent_Identity=27.0742358078603, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 46594; Mature: 46462

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVSRETKPTQPVLNLTDRQFKADPFSIYAQLRRDNPVAKAKLGSLPTWIVTRYDDVVE
CCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHH
ILKNDRVFVKNYKNAQSLEQQRKRPWMPASLRALESNMLDQDNPDHLRLRSLVHKAFTPQ
HHHCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHH
RMEEMRPRIQSIAESLLISSQQRGRGDLIADFALPLPLTVIVELLGIPTEDRQKFHRWAK
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH
YVLNSPTMLNMLLAIPAIMAQMKYLKQLFAKRRSNPQDDLLTALVQAEADGDRFSEDELV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHH
AMVFLLMLAGHETTVNLISSGTLALLQHPEQLALLRRSPELIKSAVEELVRFTAPVETAT
HHHHHHHHCCCCHHHHHHCCCCHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
ERYAAEDVIIADTKIAKGEMVLVALASANRDERQFTNPDQLDITREKNRHVGFGLGIHYC
HHHHHCCEEEECCCCCCCCEEEEEEECCCCCHHCCCCCCCEEEECCCCCCCEECHHHHHH
LGAPLARMEAQIGLQLLTDLRPNLRLAVPAEQLRWRSTAVVRGLEALPVEW
HCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCHHHCCCCC
>Mature Secondary Structure 
SSVSRETKPTQPVLNLTDRQFKADPFSIYAQLRRDNPVAKAKLGSLPTWIVTRYDDVVE
CCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHH
ILKNDRVFVKNYKNAQSLEQQRKRPWMPASLRALESNMLDQDNPDHLRLRSLVHKAFTPQ
HHHCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHH
RMEEMRPRIQSIAESLLISSQQRGRGDLIADFALPLPLTVIVELLGIPTEDRQKFHRWAK
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH
YVLNSPTMLNMLLAIPAIMAQMKYLKQLFAKRRSNPQDDLLTALVQAEADGDRFSEDELV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHH
AMVFLLMLAGHETTVNLISSGTLALLQHPEQLALLRRSPELIKSAVEELVRFTAPVETAT
HHHHHHHHCCCCHHHHHHCCCCHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
ERYAAEDVIIADTKIAKGEMVLVALASANRDERQFTNPDQLDITREKNRHVGFGLGIHYC
HHHHHCCEEEECCCCCCCCEEEEEEECCCCCHHCCCCCCCEEEECCCCCCCEECHHHHHH
LGAPLARMEAQIGLQLLTDLRPNLRLAVPAEQLRWRSTAVVRGLEALPVEW
HCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]