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The map label for this gene is eryA [H]

Identifier: 159898384

GI number: 159898384

Start: 2182669

End: 2186919

Strand: Direct

Name: eryA [H]

Synonym: Haur_1860

Alternate gene names: 159898384

Gene position: 2182669-2186919 (Clockwise)

Preceding gene: 159898383

Following gene: 159898385

Centisome position: 34.39

GC content: 53.87

Gene sequence:

>4251_bases
ATGCACGCCTATACCGACACTGATATTGCAATCATTGGGATGGCTGGACGCTTCCCAGGGGCCAACAATCTGACAACCTT
TTGGCATAATATCTGCCAAGGAATTGTCTGCATTACCGATCTAGATCTGCGACAACTTCAGGCCAGCGGAATCGACCAAG
CCCTGCTCAACGATCCCGCCTACGTCAAACGTGCGCCCTTGCTGCTTGACGATATTGCTGGCTTTGATCATAACTTTTGG
GGCATTACGCCCAATGAGGCCGCCTTGCTTGATCCACAGCAGCGGATGTTGCTGGAATGTGCATGGGAAGCCTTGGAGCA
GGCGGGCTATGCGCTTAAACAGCCACAAAAAGTTGGGGTTTTTGTGGGAGTCGGCGCAAATAACTATTTGTTGCAACAGG
TGCTAGCCAATCCAAGCGCAATCGAGCGCAATGGCGATTATGCCGTGATGCTCGCCAATGATAAAGATTATGCGCCAACC
CGAATTTCATTCAAGCTGAATTTGCTCGGGCCGAGCGTCAGCGTGCAAACCGCCTGCTCAACCTCGTTGGTGGCAACCCA
TATGGCAATTCAGAGCATTCTGAATGGCGAAAGTGCGATGGCGCTGGCTGGTGGCGCAGCGCTGCGGATTCCCCAAATGC
AAGGCCACCTCTATCAAGCTGGCATGATCCACTCGCCTGATGGCAATTGCAAGCCTTTTACCAGCGAGGCGGCGGGCACA
ATTGGCAGTAGCGGCGCTGGCATGGTGTTGCTCAAACGAGCGATTGATGCAGTAGCTGATGGCGATCCAATTTGGGCAGT
GATCAAGGGGAGCGCAATTAATAATGATGGCGCTCAGAAAGTTGGCTTTACCGCACCAAGCATCAAGGGTCAGGCCCAGG
TTGTGGCCGAAGCCTTGGCCTTGGCCGAAGTTGAGCCGAGCATGGTTGGCTACCTTGAAACCCATGGCACCGCGACCAAC
CTTGGCGATCCAATCGAGTTAGCAGCGCTCAAAAAGGTTTTTGGGGCAACTGCTGCACAAGCCTGGTGCGCCTTAGGCAC
GCTCAAAGCTAATATTGGTCATCTCGATAATGCGGCTGGGGTGGCAGGCTTGATCAAAACTGCCTTGGCCCTTCATCATC
GCCAACGACCACCAACCGCCTATGCCACCATTCCACATAGCAATTTGCAACAATCACCATTTTATTTGAACCCGACTGCG
AGCGCTTGGGATGCAAATCTTTATGCTGGAGTCAGTTCATTTGGCATTGGCGGTACGAATGCCCATGTGGTGCTGGCGGC
AGCCGAACCAATCGCCAAGCAAGCTCAGGCTGAATCATGGCAATTGCTGCCAATTTCGGCGGCCAGCGTTTGGTCGCTAG
AGCAGCAAACCGAGCGGCTGGCGGCGCATCTGCAAACTAACCCAGCGCAATCGTTGGCTGATGTAGCCTATACCCTGCAA
ACTGCACGGCAAGCCTTTGCTCAACGCAGTTTTGTGGTTGCCAAAAGCCATGAACAAGCCAGCCAAGCCTTGTTGACCAG
CCCAATCCGTGAGTTTGCCAGCCAACCGCCCAAGGTTGCTTGGCTCTTTTCGGGGCAGGGCAGCCAATGTGCTGGGATGG
CCGCTGAACTCTATCAGCAAGCACCCGCTTTTCGCCAAGCAATTGATCTGGTGAATCGCTATGCTCAACCCTTACTCGGC
TACGATCTGCGGCAAATGATGTTCGATCATTCGGGCGATCTGACGGCGACGAACGTCGCGCAGCCATGTTTGTTTATGCT
GGAATATGCCTTGGCGCAACAATGGTTGGCGTGGGGCATTCAACCACAAGCCTTGTTTGGCCATAGCATTGGCGAATATG
TGGCCGCTTGTGTTGCCAATGTGCTGGATTTACCGACTGCTGTGCGCTTGGTGGTGGTGCGTGGCCAGTTGATGAACCAA
TTGCCTAGCGGAGCGATGCTCAGCATTAACGCCAGCCGCGATCAGATTCAGCCAATCTTGCCTGCTGAACTTGATTTGGC
GGCGATCAATACCAATCAGCTGTTGGTGGTCGCTGGTGAGCATGTGGCGATCCAAGCCTTTCAGCAGCAATTGAACGAGC
GTGGCATCGAATCACGCATACTGCACACCTCGCATGCCTTTCATTCGCGAGCAATGCAGCCGATGTTGGCAGCGTTTCGC
CAGCACTTTGCCGATGTGCAACTTCAAGCGCCAACCATCCCGATCCTCTCGAATGTGAGTGGTACATGGCTGACGGCGGT
CCAAGCTACCAGTGTTGACTATTGGCTTGAACAGATTGTTAATCCAGTGCAGTGTGCTGCTTGTTTGGCCCAGTTGTTGG
CCGATGATGCTTGGATTGTGCAGGAGCTTGGGCCTGGGCATACGCTGGCAACCTTTGCCCGTGCCAGCCAGGCTGCTCAA
ACGCCGTTGATTCTCACCAGTTTGCCGCATCCACAGGTTAAGCAAGCCGATTTAGCCGTGATGTTGCAAAGTTTAGGTCA
ATTGTGGCAAGCAGGCATGACGGTGCTGTGGCAGGCTCTACATCAAACATCATGTCATAAAGTTTGGTTGCCAACCTATG
CGTTCGATCACCAACGCCATTGGATTGAGGCAGAACAGGCCCACGCACCCCGCGCAAGCAATCAAATAAGCATCAATACC
CCAACCTGGCAGGCTCAAAGCTTGGCAACCACCCCAATCCAAGCCAGCACCTGGCTGGTGTGGGGCAGCCAACCAAGCAC
TATCGAACGGCTGCTCGAACAATTTGCCGCCGATCAGCAGCTCTATATTTGCAATCAAGATACGTTTGCCCAACAGAGCA
AACAACTTAATTCTACGACCAGCCAAATCATCTATTTCAGCAACTTCAGCAGCCTCTCAGCATGGTCAGCCGCCGCTGAT
CTGTTGACGATCGCCAAGCGGGTGCGCGAGTTGGGGCTAGCCCAGGTACATTTGCATGTTGTAAGCAGCCAGAGTTTGGC
GATTGCTCCGCATGAAGATCTCAACCCGCATGATGCTGCATTGCGCGGGGTGGCGATGGTTTTGGCCCAAGAATATCCCG
AAATCAGCAGCCATTGGCTTGACCTTGATTTTACCCATCAAGCGTGGCCGAGTATGTTGGCCCAAGAGCTACAAAGTGCC
AGCGAGCCAGTGGTGGCATTGCGTGGTTTCAATCGGTTTGTGCCGCAGGCCAGGGTTGCAAGCTTACCAACCAATCAGCA
GGGCTTCCTCGTTGGTGGTTGCTATTTGATTACGGGTGGCAACGGCGGACTGGGTCGTCAAATTGCGCTCCAACTAGCCC
AACAATATCAGGCCAAGATCGCAATTTTGAGCCGTTCGCTCGTGCCTGAGTCGCCCGCTGCCTATGATTTGCAACAGCAG
ATTACCGAACGTGGTGGTGAGGCCTTAATTATTCAGGCCGATGTGGCACAGCCTAAACAATTAGCCGAAGCCTTGGCGCT
GGTCGAAACCCATTGGGGCCAATGTCATGGCCTGATTCACGCAGCGGGCAGTGCCGCCCAAATTGCTTGTACTGACACCA
CCCAAGCAACTTGGGATGCGCTGATGGCGGCCAAGCTCCAGGGAACCCAAAACCTTGCCATGATGGTGCGGCCTTGGAAA
CTCGATTGGGCGGTGGTGATGTCGTCGTTGGCCAGTGATTTGGGTGGGCTGGGCTTTGCCTGCTATGCCAGCGCCAACAT
TGCCCAACATGCCATCGTGCATCAACTCAATCAATCAAGCGCTGTACCGTGGTATTGCATCAACTGGGATGGTTGGCAAA
GCGCCGATGAAGCCGATCCTCAACGCTTGAGCTTTGAACAAGGCTGGGCTGCGCTAAGTGCGATTGTCCAACAACGCGGC
GTACTCAACCCGCAAGTAGTTGTGGGTGATGTTGCTGCACGTCGTCAGCGCTGGCTCTATCCACAACCGACAGTTGCTGC
GCCAATCACGACGCATCGTCCACGTTCAGCCAATTTCGAGGCTCCACGCAGCCAACTTGAACAGCAACTTGCGGCAATTT
GGCACGATTTACTCGGCGTAAACGAACTTAGCATTCATGATAATTTCTTCGATTTGGGCGGCCATTCGTTGTTAGCAACC
CAAGTGCTTGGCCGAATTCGTCAGCAACTTCAACTTGATCTACCGCTACAGCTGCTTTTTGAAGCGCCAACCCTTCAAGG
CTTGGCCGAGCATATTCGGCAGCAGCAGCTTAGCCAAACGTTACAAGCCCAAGCAGTTGGCGGTGGCGAGCGTGAGGAGA
TTGAGTTATGA

Upstream 100 bases:

>100_bases
CGAAGATCAAGTCCACCAACGTAGCCAACGCCAACAAAGCCAAGCCCAACGCCGTCAACGCCGCCAACAAGTCCAGCTTA
ATCTTGATGAGGAATAATTG

Downstream 100 bases:

>100_bases
GCGCGGTTCAAGCATTGCTCGAACAATTAAATGCACTCGACATAAAATTGTGGCTCGATGGGGCAAATCTGCGGGTAAAC
GCACCTAAAGGGGCATTAAC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase III; DEBS 3; ORF 3 [H]

Number of amino acids: Translated: 1416; Mature: 1416

Protein sequence:

>1416_residues
MHAYTDTDIAIIGMAGRFPGANNLTTFWHNICQGIVCITDLDLRQLQASGIDQALLNDPAYVKRAPLLLDDIAGFDHNFW
GITPNEAALLDPQQRMLLECAWEALEQAGYALKQPQKVGVFVGVGANNYLLQQVLANPSAIERNGDYAVMLANDKDYAPT
RISFKLNLLGPSVSVQTACSTSLVATHMAIQSILNGESAMALAGGAALRIPQMQGHLYQAGMIHSPDGNCKPFTSEAAGT
IGSSGAGMVLLKRAIDAVADGDPIWAVIKGSAINNDGAQKVGFTAPSIKGQAQVVAEALALAEVEPSMVGYLETHGTATN
LGDPIELAALKKVFGATAAQAWCALGTLKANIGHLDNAAGVAGLIKTALALHHRQRPPTAYATIPHSNLQQSPFYLNPTA
SAWDANLYAGVSSFGIGGTNAHVVLAAAEPIAKQAQAESWQLLPISAASVWSLEQQTERLAAHLQTNPAQSLADVAYTLQ
TARQAFAQRSFVVAKSHEQASQALLTSPIREFASQPPKVAWLFSGQGSQCAGMAAELYQQAPAFRQAIDLVNRYAQPLLG
YDLRQMMFDHSGDLTATNVAQPCLFMLEYALAQQWLAWGIQPQALFGHSIGEYVAACVANVLDLPTAVRLVVVRGQLMNQ
LPSGAMLSINASRDQIQPILPAELDLAAINTNQLLVVAGEHVAIQAFQQQLNERGIESRILHTSHAFHSRAMQPMLAAFR
QHFADVQLQAPTIPILSNVSGTWLTAVQATSVDYWLEQIVNPVQCAACLAQLLADDAWIVQELGPGHTLATFARASQAAQ
TPLILTSLPHPQVKQADLAVMLQSLGQLWQAGMTVLWQALHQTSCHKVWLPTYAFDHQRHWIEAEQAHAPRASNQISINT
PTWQAQSLATTPIQASTWLVWGSQPSTIERLLEQFAADQQLYICNQDTFAQQSKQLNSTTSQIIYFSNFSSLSAWSAAAD
LLTIAKRVRELGLAQVHLHVVSSQSLAIAPHEDLNPHDAALRGVAMVLAQEYPEISSHWLDLDFTHQAWPSMLAQELQSA
SEPVVALRGFNRFVPQARVASLPTNQQGFLVGGCYLITGGNGGLGRQIALQLAQQYQAKIAILSRSLVPESPAAYDLQQQ
ITERGGEALIIQADVAQPKQLAEALALVETHWGQCHGLIHAAGSAAQIACTDTTQATWDALMAAKLQGTQNLAMMVRPWK
LDWAVVMSSLASDLGGLGFACYASANIAQHAIVHQLNQSSAVPWYCINWDGWQSADEADPQRLSFEQGWAALSAIVQQRG
VLNPQVVVGDVAARRQRWLYPQPTVAAPITTHRPRSANFEAPRSQLEQQLAAIWHDLLGVNELSIHDNFFDLGGHSLLAT
QVLGRIRQQLQLDLPLQLLFEAPTLQGLAEHIRQQQLSQTLQAQAVGGGEREEIEL

Sequences:

>Translated_1416_residues
MHAYTDTDIAIIGMAGRFPGANNLTTFWHNICQGIVCITDLDLRQLQASGIDQALLNDPAYVKRAPLLLDDIAGFDHNFW
GITPNEAALLDPQQRMLLECAWEALEQAGYALKQPQKVGVFVGVGANNYLLQQVLANPSAIERNGDYAVMLANDKDYAPT
RISFKLNLLGPSVSVQTACSTSLVATHMAIQSILNGESAMALAGGAALRIPQMQGHLYQAGMIHSPDGNCKPFTSEAAGT
IGSSGAGMVLLKRAIDAVADGDPIWAVIKGSAINNDGAQKVGFTAPSIKGQAQVVAEALALAEVEPSMVGYLETHGTATN
LGDPIELAALKKVFGATAAQAWCALGTLKANIGHLDNAAGVAGLIKTALALHHRQRPPTAYATIPHSNLQQSPFYLNPTA
SAWDANLYAGVSSFGIGGTNAHVVLAAAEPIAKQAQAESWQLLPISAASVWSLEQQTERLAAHLQTNPAQSLADVAYTLQ
TARQAFAQRSFVVAKSHEQASQALLTSPIREFASQPPKVAWLFSGQGSQCAGMAAELYQQAPAFRQAIDLVNRYAQPLLG
YDLRQMMFDHSGDLTATNVAQPCLFMLEYALAQQWLAWGIQPQALFGHSIGEYVAACVANVLDLPTAVRLVVVRGQLMNQ
LPSGAMLSINASRDQIQPILPAELDLAAINTNQLLVVAGEHVAIQAFQQQLNERGIESRILHTSHAFHSRAMQPMLAAFR
QHFADVQLQAPTIPILSNVSGTWLTAVQATSVDYWLEQIVNPVQCAACLAQLLADDAWIVQELGPGHTLATFARASQAAQ
TPLILTSLPHPQVKQADLAVMLQSLGQLWQAGMTVLWQALHQTSCHKVWLPTYAFDHQRHWIEAEQAHAPRASNQISINT
PTWQAQSLATTPIQASTWLVWGSQPSTIERLLEQFAADQQLYICNQDTFAQQSKQLNSTTSQIIYFSNFSSLSAWSAAAD
LLTIAKRVRELGLAQVHLHVVSSQSLAIAPHEDLNPHDAALRGVAMVLAQEYPEISSHWLDLDFTHQAWPSMLAQELQSA
SEPVVALRGFNRFVPQARVASLPTNQQGFLVGGCYLITGGNGGLGRQIALQLAQQYQAKIAILSRSLVPESPAAYDLQQQ
ITERGGEALIIQADVAQPKQLAEALALVETHWGQCHGLIHAAGSAAQIACTDTTQATWDALMAAKLQGTQNLAMMVRPWK
LDWAVVMSSLASDLGGLGFACYASANIAQHAIVHQLNQSSAVPWYCINWDGWQSADEADPQRLSFEQGWAALSAIVQQRG
VLNPQVVVGDVAARRQRWLYPQPTVAAPITTHRPRSANFEAPRSQLEQQLAAIWHDLLGVNELSIHDNFFDLGGHSLLAT
QVLGRIRQQLQLDLPLQLLFEAPTLQGLAEHIRQQQLSQTLQAQAVGGGEREEIEL
>Mature_1416_residues
MHAYTDTDIAIIGMAGRFPGANNLTTFWHNICQGIVCITDLDLRQLQASGIDQALLNDPAYVKRAPLLLDDIAGFDHNFW
GITPNEAALLDPQQRMLLECAWEALEQAGYALKQPQKVGVFVGVGANNYLLQQVLANPSAIERNGDYAVMLANDKDYAPT
RISFKLNLLGPSVSVQTACSTSLVATHMAIQSILNGESAMALAGGAALRIPQMQGHLYQAGMIHSPDGNCKPFTSEAAGT
IGSSGAGMVLLKRAIDAVADGDPIWAVIKGSAINNDGAQKVGFTAPSIKGQAQVVAEALALAEVEPSMVGYLETHGTATN
LGDPIELAALKKVFGATAAQAWCALGTLKANIGHLDNAAGVAGLIKTALALHHRQRPPTAYATIPHSNLQQSPFYLNPTA
SAWDANLYAGVSSFGIGGTNAHVVLAAAEPIAKQAQAESWQLLPISAASVWSLEQQTERLAAHLQTNPAQSLADVAYTLQ
TARQAFAQRSFVVAKSHEQASQALLTSPIREFASQPPKVAWLFSGQGSQCAGMAAELYQQAPAFRQAIDLVNRYAQPLLG
YDLRQMMFDHSGDLTATNVAQPCLFMLEYALAQQWLAWGIQPQALFGHSIGEYVAACVANVLDLPTAVRLVVVRGQLMNQ
LPSGAMLSINASRDQIQPILPAELDLAAINTNQLLVVAGEHVAIQAFQQQLNERGIESRILHTSHAFHSRAMQPMLAAFR
QHFADVQLQAPTIPILSNVSGTWLTAVQATSVDYWLEQIVNPVQCAACLAQLLADDAWIVQELGPGHTLATFARASQAAQ
TPLILTSLPHPQVKQADLAVMLQSLGQLWQAGMTVLWQALHQTSCHKVWLPTYAFDHQRHWIEAEQAHAPRASNQISINT
PTWQAQSLATTPIQASTWLVWGSQPSTIERLLEQFAADQQLYICNQDTFAQQSKQLNSTTSQIIYFSNFSSLSAWSAAAD
LLTIAKRVRELGLAQVHLHVVSSQSLAIAPHEDLNPHDAALRGVAMVLAQEYPEISSHWLDLDFTHQAWPSMLAQELQSA
SEPVVALRGFNRFVPQARVASLPTNQQGFLVGGCYLITGGNGGLGRQIALQLAQQYQAKIAILSRSLVPESPAAYDLQQQ
ITERGGEALIIQADVAQPKQLAEALALVETHWGQCHGLIHAAGSAAQIACTDTTQATWDALMAAKLQGTQNLAMMVRPWK
LDWAVVMSSLASDLGGLGFACYASANIAQHAIVHQLNQSSAVPWYCINWDGWQSADEADPQRLSFEQGWAALSAIVQQRG
VLNPQVVVGDVAARRQRWLYPQPTVAAPITTHRPRSANFEAPRSQLEQQLAAIWHDLLGVNELSIHDNFFDLGGHSLLAT
QVLGRIRQQLQLDLPLQLLFEAPTLQGLAEHIRQQQLSQTLQAQAVGGGEREEIEL

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Specific For Elongation From C-10 To Unsaturated C-16 And C-18 Fatty Acids. [C]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=854, Percent_Identity=27.1662763466042, Blast_Score=238, Evalue=3e-62,
Organism=Homo sapiens, GI8923559, Length=282, Percent_Identity=29.4326241134752, Blast_Score=94, Evalue=9e-19,
Organism=Escherichia coli, GI1788663, Length=336, Percent_Identity=28.8690476190476, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1787337, Length=265, Percent_Identity=30.5660377358491, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1787334, Length=292, Percent_Identity=29.1095890410959, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17550940, Length=905, Percent_Identity=28.2872928176796, Blast_Score=329, Evalue=8e-90,
Organism=Caenorhabditis elegans, GI212642053, Length=887, Percent_Identity=26.4937993235626, Blast_Score=263, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI71983541, Length=276, Percent_Identity=29.3478260869565, Blast_Score=94, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=29.9242424242424, Blast_Score=91, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=359, Percent_Identity=25.3481894150418, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330659, Length=857, Percent_Identity=26.0210035005834, Blast_Score=234, Evalue=3e-61,
Organism=Drosophila melanogaster, GI19920632, Length=857, Percent_Identity=26.0210035005834, Blast_Score=234, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24581345, Length=862, Percent_Identity=25.9860788863109, Blast_Score=205, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24644341, Length=365, Percent_Identity=28.4931506849315, Blast_Score=92, Evalue=4e-18,

Paralogues:

None

Copy number: 24024 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 30,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020806
- InterPro:   IPR020802
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR001031
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00106 adh_short; PF08990 Docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 153097; Mature: 153097

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAYTDTDIAIIGMAGRFPGANNLTTFWHNICQGIVCITDLDLRQLQASGIDQALLNDPA
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCEEEEECCHHHHHHHCCCCHHHHCCCH
YVKRAPLLLDDIAGFDHNFWGITPNEAALLDPQQRMLLECAWEALEQAGYALKQPQKVGV
HHHHCCHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHCCHHHCCCCEEEE
FVGVGANNYLLQQVLANPSAIERNGDYAVMLANDKDYAPTRISFKLNLLGPSVSVQTACS
EEEECCCHHHHHHHHCCCCCEECCCCEEEEEECCCCCCCEEEEEEEEEECCCCEEHHHHH
TSLVATHMAIQSILNGESAMALAGGAALRIPQMQGHLYQAGMIHSPDGNCKPFTSEAAGT
HHHHHHHHHHHHHHCCCCCEEEECCCEEECCHHHCCEEECCEEECCCCCCCCCCCHHCCC
IGSSGAGMVLLKRAIDAVADGDPIWAVIKGSAINNDGAQKVGFTAPSIKGQAQVVAEALA
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCEECCCCCCCCCCCCCCCCCHHHHHHHHHH
LAEVEPSMVGYLETHGTATNLGDPIELAALKKVFGATAAQAWCALGTLKANIGHLDNAAG
HHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VAGLIKTALALHHRQRPPTAYATIPHSNLQQSPFYLNPTASAWDANLYAGVSSFGIGGTN
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCCCCCHHHHCHHHCCCCCCC
AHVVLAAAEPIAKQAQAESWQLLPISAASVWSLEQQTERLAAHLQTNPAQSLADVAYTLQ
CEEEEEECCHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TARQAFAQRSFVVAKSHEQASQALLTSPIREFASQPPKVAWLFSGQGSQCAGMAAELYQQ
HHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHH
APAFRQAIDLVNRYAQPLLGYDLRQMMFDHSGDLTATNVAQPCLFMLEYALAQQWLAWGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QPQALFGHSIGEYVAACVANVLDLPTAVRLVVVRGQLMNQLPSGAMLSINASRDQIQPIL
CHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCCCC
PAELDLAAINTNQLLVVAGEHVAIQAFQQQLNERGIESRILHTSHAFHSRAMQPMLAAFR
CCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
QHFADVQLQAPTIPILSNVSGTWLTAVQATSVDYWLEQIVNPVQCAACLAQLLADDAWIV
HHHCCCEEECCCCHHHCCCCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
QELGPGHTLATFARASQAAQTPLILTSLPHPQVKQADLAVMLQSLGQLWQAGMTVLWQAL
HHCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQTSCHKVWLPTYAFDHQRHWIEAEQAHAPRASNQISINTPTWQAQSLATTPIQASTWLV
HHCCCCEEECCCCEECCHHHHCCHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEE
WGSQPSTIERLLEQFAADQQLYICNQDTFAQQSKQLNSTTSQIIYFSNFSSLSAWSAAAD
ECCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCHHEEEEEECCCCHHHHHHHHH
LLTIAKRVRELGLAQVHLHVVSSQSLAIAPHEDLNPHDAALRGVAMVLAQEYPEISSHWL
HHHHHHHHHHCCHHEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHCEE
DLDFTHQAWPSMLAQELQSASEPVVALRGFNRFVPQARVASLPTNQQGFLVGGCYLITGG
CCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCHHHHCCCCCCCCEEEEEEEEEECC
NGGLGRQIALQLAQQYQAKIAILSRSLVPESPAAYDLQQQITERGGEALIIQADVAQPKQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHH
LAEALALVETHWGQCHGLIHAAGSAAQIACTDTTQATWDALMAAKLQGTQNLAMMVRPWK
HHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCC
LDWAVVMSSLASDLGGLGFACYASANIAQHAIVHQLNQSSAVPWYCINWDGWQSADEADP
CHHHHHHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCC
QRLSFEQGWAALSAIVQQRGVLNPQVVVGDVAARRQRWLYPQPTVAAPITTHRPRSANFE
HHCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
APRSQLEQQLAAIWHDLLGVNELSIHDNFFDLGGHSLLATQVLGRIRQQLQLDLPLQLLF
CHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
EAPTLQGLAEHIRQQQLSQTLQAQAVGGGEREEIEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHAYTDTDIAIIGMAGRFPGANNLTTFWHNICQGIVCITDLDLRQLQASGIDQALLNDPA
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCEEEEECCHHHHHHHCCCCHHHHCCCH
YVKRAPLLLDDIAGFDHNFWGITPNEAALLDPQQRMLLECAWEALEQAGYALKQPQKVGV
HHHHCCHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHCCHHHCCCCEEEE
FVGVGANNYLLQQVLANPSAIERNGDYAVMLANDKDYAPTRISFKLNLLGPSVSVQTACS
EEEECCCHHHHHHHHCCCCCEECCCCEEEEEECCCCCCCEEEEEEEEEECCCCEEHHHHH
TSLVATHMAIQSILNGESAMALAGGAALRIPQMQGHLYQAGMIHSPDGNCKPFTSEAAGT
HHHHHHHHHHHHHHCCCCCEEEECCCEEECCHHHCCEEECCEEECCCCCCCCCCCHHCCC
IGSSGAGMVLLKRAIDAVADGDPIWAVIKGSAINNDGAQKVGFTAPSIKGQAQVVAEALA
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCEECCCCCCCCCCCCCCCCCHHHHHHHHHH
LAEVEPSMVGYLETHGTATNLGDPIELAALKKVFGATAAQAWCALGTLKANIGHLDNAAG
HHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VAGLIKTALALHHRQRPPTAYATIPHSNLQQSPFYLNPTASAWDANLYAGVSSFGIGGTN
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCCCCCHHHHCHHHCCCCCCC
AHVVLAAAEPIAKQAQAESWQLLPISAASVWSLEQQTERLAAHLQTNPAQSLADVAYTLQ
CEEEEEECCHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TARQAFAQRSFVVAKSHEQASQALLTSPIREFASQPPKVAWLFSGQGSQCAGMAAELYQQ
HHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHH
APAFRQAIDLVNRYAQPLLGYDLRQMMFDHSGDLTATNVAQPCLFMLEYALAQQWLAWGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QPQALFGHSIGEYVAACVANVLDLPTAVRLVVVRGQLMNQLPSGAMLSINASRDQIQPIL
CHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCCCC
PAELDLAAINTNQLLVVAGEHVAIQAFQQQLNERGIESRILHTSHAFHSRAMQPMLAAFR
CCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
QHFADVQLQAPTIPILSNVSGTWLTAVQATSVDYWLEQIVNPVQCAACLAQLLADDAWIV
HHHCCCEEECCCCHHHCCCCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
QELGPGHTLATFARASQAAQTPLILTSLPHPQVKQADLAVMLQSLGQLWQAGMTVLWQAL
HHCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQTSCHKVWLPTYAFDHQRHWIEAEQAHAPRASNQISINTPTWQAQSLATTPIQASTWLV
HHCCCCEEECCCCEECCHHHHCCHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEE
WGSQPSTIERLLEQFAADQQLYICNQDTFAQQSKQLNSTTSQIIYFSNFSSLSAWSAAAD
ECCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCHHEEEEEECCCCHHHHHHHHH
LLTIAKRVRELGLAQVHLHVVSSQSLAIAPHEDLNPHDAALRGVAMVLAQEYPEISSHWL
HHHHHHHHHHCCHHEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHCEE
DLDFTHQAWPSMLAQELQSASEPVVALRGFNRFVPQARVASLPTNQQGFLVGGCYLITGG
CCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCHHHHCCCCCCCCEEEEEEEEEECC
NGGLGRQIALQLAQQYQAKIAILSRSLVPESPAAYDLQQQITERGGEALIIQADVAQPKQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHH
LAEALALVETHWGQCHGLIHAAGSAAQIACTDTTQATWDALMAAKLQGTQNLAMMVRPWK
HHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCC
LDWAVVMSSLASDLGGLGFACYASANIAQHAIVHQLNQSSAVPWYCINWDGWQSADEADP
CHHHHHHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCC
QRLSFEQGWAALSAIVQQRGVLNPQVVVGDVAARRQRWLYPQPTVAAPITTHRPRSANFE
HHCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
APRSQLEQQLAAIWHDLLGVNELSIHDNFFDLGGHSLLATQVLGRIRQQLQLDLPLQLLF
CHHHHHHHHHHHHHHHHHCCCEEEECCCHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
EAPTLQGLAEHIRQQQLSQTLQAQAVGGGEREEIEL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2234082; 2024119; 1740151 [H]