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The map label for this gene is dhbF [H]

Identifier: 159898329

GI number: 159898329

Start: 2094746

End: 2098987

Strand: Direct

Name: dhbF [H]

Synonym: Haur_1805

Alternate gene names: 159898329

Gene position: 2094746-2098987 (Clockwise)

Preceding gene: 159898328

Following gene: 159898330

Centisome position: 33.01

GC content: 55.04

Gene sequence:

>4242_bases
ATGGCTAAGCTGGCGCTATCGGCGGCACAACATGGCATTTGGCTGGGTCAACAGCTCGATCCGAGTAGTCCGCTGTATAA
CACAGCCGAATATGTGGCTCTGCGCGGTGCGGTTGAGCTTACCAATTTGACCGCTGCGATTAAGCAGGCCTTTGCTGAAG
CCGCAACCCTGCATTTGCGTTTTGGGCTTGAGCATGATCAGCCGTATGCGCTGGTTGAGCCACAGCCAATTAACTTGACC
GTGCATGATTTGCGTGATTTACCCGATGCTGAAGTACGAGCCATAGCTTGGATGCAGCACGATTTGGGCAATGTGGTCGA
TCTAGCAACCGGCCCGTTGTTCAACACGGCGATTTTGCAACTTGCTGATGATCAGGTGTGGTGGTATTTGCGAGCGCATC
ACATTGCCTTAGATGGCTATAGTTTTGCTTTGCTCACCAAGCGCGTCGCCGAAATTTACTCGGCATTGCAAACCAAGGCC
ACGCTCAGCCCAAGCTTTGGCGAATTGGTCCCAGTAATTGCTGAAGATCACGCCTATCAAGTCTCAATTCAGGCCACGCT
TGATCGCGAATTTTGGGTTAATCGCTTTGCAGATAATCCGCAAGTGGTCAGCCTGACTCAGCAAACTGCCCTATCGCAGC
CGCGCAGCATTCGCTTGAGCACGGCTTTAGCGAACGACTTGATCGAGCGATTGACTGCAATCGCCAAGCCCAGCCGTAGC
ACATGGCCCGATGCCTTGATGGCGGTGGTGGCAGCCTATCTCGCCCGCTGGAACAACAGCGAGAGCGTCGTTTTGGGCAT
GCCCTTGATGAGCCGTTTGGGTTCGGTGGCGTTGCGTGTGCCGTGTATGGCCATGAATATTGTGCCGCTGTGTCTTAACG
TTGCGGCTGAGCATGATTTGGCCCAATTAACTGCGGTAGTGGCAGCCGAACGCAATGCCTTCCGCAAGCATGGCCGCTAT
CGCTATGAGCAGTTGCGCCGCGATTTGGGCTTTGTTGGCGCTGGGCGGCGCTTGTTTGGGCCTGTCGTCAATATTATGCC
CTTCGATCATCCGCTGAATTTTGGTGATTGCCAAGCCCAGAGCACTACACTCACCGCTGGCCCAGTCGAAGATTTGGCCT
TCAACGTGATTTTGCGCGGCAACCAACTCTATCTGACGCTTGAGGCCAATCCGGCTTGCTACAGCCAAGCAGCGCTTGAA
TATCATTTTGCGGCAATTCAACACCTATTAAATGGATGGCTGGCAAATCCAAGCATACCTGTGGCTGAGCAGCAGGTTTT
GCCAGCGCCGCTTGTGCTTGATGGCGGCGAGTTGCGCTTGCCGCTGACCAGCGTGATCGAGCGAATTTTACATAATGCCA
GGCAACAGCCGCACGCTTTGGCTTTGGTTACCGACACTGAGCAACTGAGCTATGCCGAGTTGGCGAGCCACGTCCATGCG
TGGGCAGGCCAATTGGTGCAGCGCGGGGTAACTGCTGGCAGCGTGGTTGGCGTGGCTTTGCCGCGTAGCCGCGAGGCAAT
TGTCGCAATTTTGGCGACGCTTTGTTGTGGGGCAGCCTATCTGCCACTTGACCCGCAATGGCCGCAAAGCCGCTTGGCGA
GTGTCGTGGCGCAAGCCCAACCAGTGCTAGTTTTGGCACAGCAAGCTTTTGATCTGCCCAATTTGTTGTTGGTCGAGCAG
TTGAGCAAGGCCAATGCATGGTTCGAGGCACGGGTCGATTTGGCCCAACCAGCCTACATCATGTATACCTCTGGCTCGAC
TGGCGAGCCAAAAGGTGTGGTGATTAGCCATCAAGCCTTGGCGGGTTTTGTGCAGGCTGCGGCTGAGCGTTACGCAATCA
GCGCCGCTGATCGGGTGCTGCAATTTGCCCCATTAGCTTTTGATGCTAGCGTTGAAGAAATTTTTGTGACGCTTTGCCAA
GGCGCGACCTTGGTGTTGCGCAACGATGCCATGCTCGAATCGTTACAGCGCTTTGTGGCCGCCTGCCAAGCGCATGCGAT
TAGTGTGCTCGATTTGCCAACCGCCTTTTGGCATGAATTAGCCGATAGTGTGGCCCAAGGCGCGGTGCAGTTGCCCGAAT
GTTTGCGGGTGGTAATTATCGGGGGCGAGGCGGCTCTGCCAGAGCGGGTTCAAGGCTGGTTGAACGTGGTTGCGCCGAAT
GTGCGTTTGTTCAACACCTATGGCCCAACCGAGGCGACCGTGGTGGCGACCGTGGCCGAATTGAGCGACCCCAACCAGCC
AATTACGATTGGCCGACCATTGGCTGGGGTGCAAGCAGCCATTTTGGGCAGCGACCAGCGGCCAATTTTTGCAGGCGATG
TTGGCGATTTATATCTGCTGGGCAATGGCTTAGCAACTGGCTACTATCAACGCCCCGATTTGGATGCGCTGAATTTTGGC
CAACTTAGCCAATTGCCGCATGCGCCCCGCGCCTATCGCACTGGCGATCGAGTGCGTTTGTTCGCAGGTCAGTTACAGTT
TGTGGGTCGCAGCGACGACGAATTCAAAATTAGCGGCCAGCGTGTTACGCCTGCCGAAATTGAATCGGTCTTTTTGCGGC
ATACAGCGGTGCGCGAAGTAGCGGTGATTGGCCAGCAGCTTGGCAATGCGAGCAAGCGCTTGTTTGCAGCAGTCGTTGTC
AGCGATGCTAGTTTGAGCGTGGCTGAATTGCGCAATCACGCCAGCCAACATCTGCCAGCGGCGGTCATTCCGGCGGCGAT
CACGATTGTTGAACGCTTGCCGCGCAGCAGTGCAGGCAAGATCGATCGCAAGGCTGTGGCGGCCTTAGCGCCAGCACCAG
TGATGGTGAATGCTGCGATCAACGATACGCCAGCATTAATTCGTCAAGTTTGGGCCGAAGTTTTGGGCCAAACTGAATTC
AACGATGAAGCCGATTTCTTTGGCTTGGGCGGTCAATCGCTGCAAACCATTCAGGTTGCCAATCGTTTGGGTATGGCCTT
GGGTCGCGAAGTAACCGCCGCCTTGATCTTCCGCTATCCCACGATTGCGGGCTTGAGCCAAGCGCTCGACCCTGAATTTG
AGCAGGCTCCTGAGGCAGCGCCGCAATTTTTGAGCGATGCCAATTTGCCTGAGCAGATTGTGCCCAAACAACTGAATGCC
CAGCCACGGCCAATCCAAACCGTGCTGTTGACTGGGGCAACTGGCTTTGTCGGGGCACATCTGTTGGCCGAATTGCTTAG
CACAACCACCACCAACGTGATTTGTGTGGTGCGAGCTGGCTCGAATGCGGCAGCCTTTGAGCGGTTGCAAGCAAGTTTGC
AACACTACGAATTGCCAAGCGAGCAGCTTGCCGAGCAGGTTGAAGCTTGGCAGGGCGATTTGGCTCAGCCCCAATTTGGG
CTTGACGATCAGCAATGGCAAAGCTTGATCGAACGTTGCGATCTGATTTATCACAATGCGGCGATGGTCAGCGTGGTTCG
CGAGTATAGCAGCTTGCGGGCGGTCAACGTCAACGCCACCAGCGAAATTTTGCGTTTGGCAGCGGTGCATTGCACCCCAG
TGCATTACGTTTCGACCTTGGCAGTTTCACCACCGCAAAGCGTGATGCACCGCGTGCCCGAAGATTTTGTGGCGGCGCAT
GCTGGCCTACGCGATGGCTATAGCCAAAGCAAATGGGTTGCCGAACGCTTGCTCGAACAAGCGGCTACCCGTGGTTTGCC
GGTTGCTGTTTATCGTTTGGGGCGGGTAGTTGGCCCAAATCAAAGCAATTTCGTCAATCAAGATGATTTATTTTGGCGGA
TTGTCCAAGCAGGTGTGCCGCGTGGCTTATTGCCCAGCCTGCCTGTCGAGGAAATCTGGAATCCAGTTGATTTTGCTGCA
CAGACAATCGTGCAATTTAGCCATAATCATCGCGGCGTGCGCGTGTATAACCTTGCTCCCAACGAACCAATCAGCTTTGC
CCAACTTTTGGGCTGGGTTGGCGAGTATGGCTATGCCGTGCAATTGTGCAGGGTTGAGCAATGGTATCAAGCGTTGCGTA
ACGCCGACGATGCGATGAGTCAGGCGACTCTGACCTTCTTTGAGCGCCAGGCTGATGGTGGGGAACTGCCCAGCGCAATT
GGTACGATTGAAAACAAACGCTTGCTGCAAACGCTTGCAGCGCATGGCATTGCTGTGCCTGTGATCGATCGCGAGCGCTT
CTTTGGCTATCTTGAGCGGTGTATTCGAACGGGTTTATTGCCCGCACCCGATTTACGCCAGACTAGTATTGGTATTCGCT
AA

Upstream 100 bases:

>100_bases
GCAGCAGGCTGTGAAGTTGGTTTTGCTGAATTGGCCGAAACCCCAACTTTAGCCGAATGGTGGCAACGCCGTTTTGCCGC
ACCACTCCTGGAGCAAGCTC

Downstream 100 bases:

>100_bases
AATTTTTAGCATACAAAGGAATTACACCAATGACATCCCTTTCAGTTCGTTTTCGTTCGTTATTGGCCTTACTCGCGCTT
GTGACCTTGGCTGCTTGTGG

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1413; Mature: 1412

Protein sequence:

>1413_residues
MAKLALSAAQHGIWLGQQLDPSSPLYNTAEYVALRGAVELTNLTAAIKQAFAEAATLHLRFGLEHDQPYALVEPQPINLT
VHDLRDLPDAEVRAIAWMQHDLGNVVDLATGPLFNTAILQLADDQVWWYLRAHHIALDGYSFALLTKRVAEIYSALQTKA
TLSPSFGELVPVIAEDHAYQVSIQATLDREFWVNRFADNPQVVSLTQQTALSQPRSIRLSTALANDLIERLTAIAKPSRS
TWPDALMAVVAAYLARWNNSESVVLGMPLMSRLGSVALRVPCMAMNIVPLCLNVAAEHDLAQLTAVVAAERNAFRKHGRY
RYEQLRRDLGFVGAGRRLFGPVVNIMPFDHPLNFGDCQAQSTTLTAGPVEDLAFNVILRGNQLYLTLEANPACYSQAALE
YHFAAIQHLLNGWLANPSIPVAEQQVLPAPLVLDGGELRLPLTSVIERILHNARQQPHALALVTDTEQLSYAELASHVHA
WAGQLVQRGVTAGSVVGVALPRSREAIVAILATLCCGAAYLPLDPQWPQSRLASVVAQAQPVLVLAQQAFDLPNLLLVEQ
LSKANAWFEARVDLAQPAYIMYTSGSTGEPKGVVISHQALAGFVQAAAERYAISAADRVLQFAPLAFDASVEEIFVTLCQ
GATLVLRNDAMLESLQRFVAACQAHAISVLDLPTAFWHELADSVAQGAVQLPECLRVVIIGGEAALPERVQGWLNVVAPN
VRLFNTYGPTEATVVATVAELSDPNQPITIGRPLAGVQAAILGSDQRPIFAGDVGDLYLLGNGLATGYYQRPDLDALNFG
QLSQLPHAPRAYRTGDRVRLFAGQLQFVGRSDDEFKISGQRVTPAEIESVFLRHTAVREVAVIGQQLGNASKRLFAAVVV
SDASLSVAELRNHASQHLPAAVIPAAITIVERLPRSSAGKIDRKAVAALAPAPVMVNAAINDTPALIRQVWAEVLGQTEF
NDEADFFGLGGQSLQTIQVANRLGMALGREVTAALIFRYPTIAGLSQALDPEFEQAPEAAPQFLSDANLPEQIVPKQLNA
QPRPIQTVLLTGATGFVGAHLLAELLSTTTTNVICVVRAGSNAAAFERLQASLQHYELPSEQLAEQVEAWQGDLAQPQFG
LDDQQWQSLIERCDLIYHNAAMVSVVREYSSLRAVNVNATSEILRLAAVHCTPVHYVSTLAVSPPQSVMHRVPEDFVAAH
AGLRDGYSQSKWVAERLLEQAATRGLPVAVYRLGRVVGPNQSNFVNQDDLFWRIVQAGVPRGLLPSLPVEEIWNPVDFAA
QTIVQFSHNHRGVRVYNLAPNEPISFAQLLGWVGEYGYAVQLCRVEQWYQALRNADDAMSQATLTFFERQADGGELPSAI
GTIENKRLLQTLAAHGIAVPVIDRERFFGYLERCIRTGLLPAPDLRQTSIGIR

Sequences:

>Translated_1413_residues
MAKLALSAAQHGIWLGQQLDPSSPLYNTAEYVALRGAVELTNLTAAIKQAFAEAATLHLRFGLEHDQPYALVEPQPINLT
VHDLRDLPDAEVRAIAWMQHDLGNVVDLATGPLFNTAILQLADDQVWWYLRAHHIALDGYSFALLTKRVAEIYSALQTKA
TLSPSFGELVPVIAEDHAYQVSIQATLDREFWVNRFADNPQVVSLTQQTALSQPRSIRLSTALANDLIERLTAIAKPSRS
TWPDALMAVVAAYLARWNNSESVVLGMPLMSRLGSVALRVPCMAMNIVPLCLNVAAEHDLAQLTAVVAAERNAFRKHGRY
RYEQLRRDLGFVGAGRRLFGPVVNIMPFDHPLNFGDCQAQSTTLTAGPVEDLAFNVILRGNQLYLTLEANPACYSQAALE
YHFAAIQHLLNGWLANPSIPVAEQQVLPAPLVLDGGELRLPLTSVIERILHNARQQPHALALVTDTEQLSYAELASHVHA
WAGQLVQRGVTAGSVVGVALPRSREAIVAILATLCCGAAYLPLDPQWPQSRLASVVAQAQPVLVLAQQAFDLPNLLLVEQ
LSKANAWFEARVDLAQPAYIMYTSGSTGEPKGVVISHQALAGFVQAAAERYAISAADRVLQFAPLAFDASVEEIFVTLCQ
GATLVLRNDAMLESLQRFVAACQAHAISVLDLPTAFWHELADSVAQGAVQLPECLRVVIIGGEAALPERVQGWLNVVAPN
VRLFNTYGPTEATVVATVAELSDPNQPITIGRPLAGVQAAILGSDQRPIFAGDVGDLYLLGNGLATGYYQRPDLDALNFG
QLSQLPHAPRAYRTGDRVRLFAGQLQFVGRSDDEFKISGQRVTPAEIESVFLRHTAVREVAVIGQQLGNASKRLFAAVVV
SDASLSVAELRNHASQHLPAAVIPAAITIVERLPRSSAGKIDRKAVAALAPAPVMVNAAINDTPALIRQVWAEVLGQTEF
NDEADFFGLGGQSLQTIQVANRLGMALGREVTAALIFRYPTIAGLSQALDPEFEQAPEAAPQFLSDANLPEQIVPKQLNA
QPRPIQTVLLTGATGFVGAHLLAELLSTTTTNVICVVRAGSNAAAFERLQASLQHYELPSEQLAEQVEAWQGDLAQPQFG
LDDQQWQSLIERCDLIYHNAAMVSVVREYSSLRAVNVNATSEILRLAAVHCTPVHYVSTLAVSPPQSVMHRVPEDFVAAH
AGLRDGYSQSKWVAERLLEQAATRGLPVAVYRLGRVVGPNQSNFVNQDDLFWRIVQAGVPRGLLPSLPVEEIWNPVDFAA
QTIVQFSHNHRGVRVYNLAPNEPISFAQLLGWVGEYGYAVQLCRVEQWYQALRNADDAMSQATLTFFERQADGGELPSAI
GTIENKRLLQTLAAHGIAVPVIDRERFFGYLERCIRTGLLPAPDLRQTSIGIR
>Mature_1412_residues
AKLALSAAQHGIWLGQQLDPSSPLYNTAEYVALRGAVELTNLTAAIKQAFAEAATLHLRFGLEHDQPYALVEPQPINLTV
HDLRDLPDAEVRAIAWMQHDLGNVVDLATGPLFNTAILQLADDQVWWYLRAHHIALDGYSFALLTKRVAEIYSALQTKAT
LSPSFGELVPVIAEDHAYQVSIQATLDREFWVNRFADNPQVVSLTQQTALSQPRSIRLSTALANDLIERLTAIAKPSRST
WPDALMAVVAAYLARWNNSESVVLGMPLMSRLGSVALRVPCMAMNIVPLCLNVAAEHDLAQLTAVVAAERNAFRKHGRYR
YEQLRRDLGFVGAGRRLFGPVVNIMPFDHPLNFGDCQAQSTTLTAGPVEDLAFNVILRGNQLYLTLEANPACYSQAALEY
HFAAIQHLLNGWLANPSIPVAEQQVLPAPLVLDGGELRLPLTSVIERILHNARQQPHALALVTDTEQLSYAELASHVHAW
AGQLVQRGVTAGSVVGVALPRSREAIVAILATLCCGAAYLPLDPQWPQSRLASVVAQAQPVLVLAQQAFDLPNLLLVEQL
SKANAWFEARVDLAQPAYIMYTSGSTGEPKGVVISHQALAGFVQAAAERYAISAADRVLQFAPLAFDASVEEIFVTLCQG
ATLVLRNDAMLESLQRFVAACQAHAISVLDLPTAFWHELADSVAQGAVQLPECLRVVIIGGEAALPERVQGWLNVVAPNV
RLFNTYGPTEATVVATVAELSDPNQPITIGRPLAGVQAAILGSDQRPIFAGDVGDLYLLGNGLATGYYQRPDLDALNFGQ
LSQLPHAPRAYRTGDRVRLFAGQLQFVGRSDDEFKISGQRVTPAEIESVFLRHTAVREVAVIGQQLGNASKRLFAAVVVS
DASLSVAELRNHASQHLPAAVIPAAITIVERLPRSSAGKIDRKAVAALAPAPVMVNAAINDTPALIRQVWAEVLGQTEFN
DEADFFGLGGQSLQTIQVANRLGMALGREVTAALIFRYPTIAGLSQALDPEFEQAPEAAPQFLSDANLPEQIVPKQLNAQ
PRPIQTVLLTGATGFVGAHLLAELLSTTTTNVICVVRAGSNAAAFERLQASLQHYELPSEQLAEQVEAWQGDLAQPQFGL
DDQQWQSLIERCDLIYHNAAMVSVVREYSSLRAVNVNATSEILRLAAVHCTPVHYVSTLAVSPPQSVMHRVPEDFVAAHA
GLRDGYSQSKWVAERLLEQAATRGLPVAVYRLGRVVGPNQSNFVNQDDLFWRIVQAGVPRGLLPSLPVEEIWNPVDFAAQ
TIVQFSHNHRGVRVYNLAPNEPISFAQLLGWVGEYGYAVQLCRVEQWYQALRNADDAMSQATLTFFERQADGGELPSAIG
TIENKRLLQTLAAHGIAVPVIDRERFFGYLERCIRTGLLPAPDLRQTSIGIR

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=470, Percent_Identity=26.1702127659574, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI187761343, Length=470, Percent_Identity=26.1702127659574, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI45580730, Length=437, Percent_Identity=24.7139588100687, Blast_Score=106, Evalue=2e-22,
Organism=Homo sapiens, GI156151445, Length=535, Percent_Identity=23.1775700934579, Blast_Score=95, Evalue=4e-19,
Organism=Homo sapiens, GI157311624, Length=481, Percent_Identity=23.9085239085239, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI157311622, Length=481, Percent_Identity=23.9085239085239, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI28416953, Length=562, Percent_Identity=23.4875444839858, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI58082049, Length=481, Percent_Identity=23.9085239085239, Blast_Score=88, Evalue=7e-17,
Organism=Homo sapiens, GI122937307, Length=504, Percent_Identity=23.015873015873, Blast_Score=87, Evalue=2e-16,
Organism=Homo sapiens, GI115511026, Length=508, Percent_Identity=23.6220472440945, Blast_Score=72, Evalue=4e-12,
Organism=Escherichia coli, GI1786801, Length=1065, Percent_Identity=31.924882629108, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI145693145, Length=516, Percent_Identity=24.6124031007752, Blast_Score=114, Evalue=5e-26,
Organism=Escherichia coli, GI1788595, Length=427, Percent_Identity=28.3372365339578, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1788107, Length=356, Percent_Identity=26.123595505618, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI221142682, Length=522, Percent_Identity=22.7969348659004, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1786810, Length=527, Percent_Identity=23.9089184060721, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17550940, Length=932, Percent_Identity=20.9227467811159, Blast_Score=140, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17556356, Length=538, Percent_Identity=24.3494423791822, Blast_Score=126, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17538037, Length=558, Percent_Identity=24.1935483870968, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17531443, Length=527, Percent_Identity=23.5294117647059, Blast_Score=104, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17557194, Length=551, Percent_Identity=25.0453720508167, Blast_Score=101, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71996755, Length=509, Percent_Identity=20.8251473477407, Blast_Score=90, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI32564420, Length=441, Percent_Identity=25.3968253968254, Blast_Score=87, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI32564422, Length=441, Percent_Identity=25.3968253968254, Blast_Score=87, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17559526, Length=369, Percent_Identity=25.2032520325203, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560140, Length=546, Percent_Identity=22.1611721611722, Blast_Score=81, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71985884, Length=365, Percent_Identity=24.6575342465753, Blast_Score=77, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982997, Length=571, Percent_Identity=23.292469352014, Blast_Score=74, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71983001, Length=571, Percent_Identity=23.292469352014, Blast_Score=73, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=1144, Percent_Identity=24.4755244755245, Blast_Score=274, Evalue=7e-74,
Organism=Saccharomyces cerevisiae, GI6319699, Length=364, Percent_Identity=23.6263736263736, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648676, Length=539, Percent_Identity=26.3450834879406, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21355225, Length=562, Percent_Identity=24.1992882562278, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356947, Length=521, Percent_Identity=21.4971209213052, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582852, Length=578, Percent_Identity=22.318339100346, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24581924, Length=374, Percent_Identity=25.1336898395722, Blast_Score=75, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648257, Length=377, Percent_Identity=25.7294429708223, Blast_Score=68, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 153747; Mature: 153616

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLALSAAQHGIWLGQQLDPSSPLYNTAEYVALRGAVELTNLTAAIKQAFAEAATLHLR
CCCHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEEE
FGLEHDQPYALVEPQPINLTVHDLRDLPDAEVRAIAWMQHDLGNVVDLATGPLFNTAILQ
ECCCCCCCEEEECCCCCCEEHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHH
LADDQVWWYLRAHHIALDGYSFALLTKRVAEIYSALQTKATLSPSFGELVPVIAEDHAYQ
HCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCEEE
VSIQATLDREFWVNRFADNPQVVSLTQQTALSQPRSIRLSTALANDLIERLTAIAKPSRS
EEEEEECCHHHHHHHCCCCCCEEEEEHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCC
TWPDALMAVVAAYLARWNNSESVVLGMPLMSRLGSVALRVPCMAMNIVPLCLNVAAEHDL
CCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLTAVVAAERNAFRKHGRYRYEQLRRDLGFVGAGRRLFGPVVNIMPFDHPLNFGDCQAQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
STTLTAGPVEDLAFNVILRGNQLYLTLEANPACYSQAALEYHFAAIQHLLNGWLANPSIP
CCEEECCCHHHHEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VAEQQVLPAPLVLDGGELRLPLTSVIERILHNARQQPHALALVTDTEQLSYAELASHVHA
CCCHHCCCCCEEECCCCEECCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHH
WAGQLVQRGVTAGSVVGVALPRSREAIVAILATLCCGAAYLPLDPQWPQSRLASVVAQAQ
HHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHCC
PVLVLAQQAFDLPNLLLVEQLSKANAWFEARVDLAQPAYIMYTSGSTGEPKGVVISHQAL
CHHEEHHHHCCCCHHHHHHHHHHCCCHHEEEECCCCCEEEEEECCCCCCCCCEEEEHHHH
AGFVQAAAERYAISAADRVLQFAPLAFDASVEEIFVTLCQGATLVLRNDAMLESLQRFVA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHH
ACQAHAISVLDLPTAFWHELADSVAQGAVQLPECLRVVIIGGEAALPERVQGWLNVVAPN
HHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCC
VRLFNTYGPTEATVVATVAELSDPNQPITIGRPLAGVQAAILGSDQRPIFAGDVGDLYLL
EEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHHEECCCCCCEEECCCCCEEEE
GNGLATGYYQRPDLDALNFGQLSQLPHAPRAYRTGDRVRLFAGQLQFVGRSDDEFKISGQ
ECCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCEEECCC
RVTPAEIESVFLRHTAVREVAVIGQQLGNASKRLFAAVVVSDASLSVAELRNHASQHLPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCHHHHHHHHHHHCCCH
AVIPAAITIVERLPRSSAGKIDRKAVAALAPAPVMVNAAINDTPALIRQVWAEVLGQTEF
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCC
NDEADFFGLGGQSLQTIQVANRLGMALGREVTAALIFRYPTIAGLSQALDPEFEQAPEAA
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHCCHHH
PQFLSDANLPEQIVPKQLNAQPRPIQTVLLTGATGFVGAHLLAELLSTTTTNVICVVRAG
HHHHHCCCCCHHHCCHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECC
SNAAAFERLQASLQHYELPSEQLAEQVEAWQGDLAQPQFGLDDQQWQSLIERCDLIYHNA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AMVSVVREYSSLRAVNVNATSEILRLAAVHCTPVHYVSTLAVSPPQSVMHRVPEDFVAAH
HHHHHHHHHHHCEEEECCHHHHHHHHHHHHCCHHHHHHHEECCCHHHHHHHCCHHHHHHH
AGLRDGYSQSKWVAERLLEQAATRGLPVAVYRLGRVVGPNQSNFVNQDDLFWRIVQAGVP
HHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCC
RGLLPSLPVEEIWNPVDFAAQTIVQFSHNHRGVRVYNLAPNEPISFAQLLGWVGEYGYAV
CCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHH
QLCRVEQWYQALRNADDAMSQATLTFFERQADGGELPSAIGTIENKRLLQTLAAHGIAVP
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEE
VIDRERFFGYLERCIRTGLLPAPDLRQTSIGIR
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKLALSAAQHGIWLGQQLDPSSPLYNTAEYVALRGAVELTNLTAAIKQAFAEAATLHLR
CCHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEEE
FGLEHDQPYALVEPQPINLTVHDLRDLPDAEVRAIAWMQHDLGNVVDLATGPLFNTAILQ
ECCCCCCCEEEECCCCCCEEHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHH
LADDQVWWYLRAHHIALDGYSFALLTKRVAEIYSALQTKATLSPSFGELVPVIAEDHAYQ
HCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCEEE
VSIQATLDREFWVNRFADNPQVVSLTQQTALSQPRSIRLSTALANDLIERLTAIAKPSRS
EEEEEECCHHHHHHHCCCCCCEEEEEHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCC
TWPDALMAVVAAYLARWNNSESVVLGMPLMSRLGSVALRVPCMAMNIVPLCLNVAAEHDL
CCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLTAVVAAERNAFRKHGRYRYEQLRRDLGFVGAGRRLFGPVVNIMPFDHPLNFGDCQAQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
STTLTAGPVEDLAFNVILRGNQLYLTLEANPACYSQAALEYHFAAIQHLLNGWLANPSIP
CCEEECCCHHHHEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VAEQQVLPAPLVLDGGELRLPLTSVIERILHNARQQPHALALVTDTEQLSYAELASHVHA
CCCHHCCCCCEEECCCCEECCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHH
WAGQLVQRGVTAGSVVGVALPRSREAIVAILATLCCGAAYLPLDPQWPQSRLASVVAQAQ
HHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHCC
PVLVLAQQAFDLPNLLLVEQLSKANAWFEARVDLAQPAYIMYTSGSTGEPKGVVISHQAL
CHHEEHHHHCCCCHHHHHHHHHHCCCHHEEEECCCCCEEEEEECCCCCCCCCEEEEHHHH
AGFVQAAAERYAISAADRVLQFAPLAFDASVEEIFVTLCQGATLVLRNDAMLESLQRFVA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHH
ACQAHAISVLDLPTAFWHELADSVAQGAVQLPECLRVVIIGGEAALPERVQGWLNVVAPN
HHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCC
VRLFNTYGPTEATVVATVAELSDPNQPITIGRPLAGVQAAILGSDQRPIFAGDVGDLYLL
EEEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHHEECCCCCCEEECCCCCEEEE
GNGLATGYYQRPDLDALNFGQLSQLPHAPRAYRTGDRVRLFAGQLQFVGRSDDEFKISGQ
ECCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCEEECCC
RVTPAEIESVFLRHTAVREVAVIGQQLGNASKRLFAAVVVSDASLSVAELRNHASQHLPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCHHHHHHHHHHHCCCH
AVIPAAITIVERLPRSSAGKIDRKAVAALAPAPVMVNAAINDTPALIRQVWAEVLGQTEF
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCC
NDEADFFGLGGQSLQTIQVANRLGMALGREVTAALIFRYPTIAGLSQALDPEFEQAPEAA
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHCCHHH
PQFLSDANLPEQIVPKQLNAQPRPIQTVLLTGATGFVGAHLLAELLSTTTTNVICVVRAG
HHHHHCCCCCHHHCCHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECC
SNAAAFERLQASLQHYELPSEQLAEQVEAWQGDLAQPQFGLDDQQWQSLIERCDLIYHNA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AMVSVVREYSSLRAVNVNATSEILRLAAVHCTPVHYVSTLAVSPPQSVMHRVPEDFVAAH
HHHHHHHHHHHCEEEECCHHHHHHHHHHHHCCHHHHHHHEECCCHHHHHHHCCHHHHHHH
AGLRDGYSQSKWVAERLLEQAATRGLPVAVYRLGRVVGPNQSNFVNQDDLFWRIVQAGVP
HHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCC
RGLLPSLPVEEIWNPVDFAAQTIVQFSHNHRGVRVYNLAPNEPISFAQLLGWVGEYGYAV
CCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHH
QLCRVEQWYQALRNADDAMSQATLTFFERQADGGELPSAIGTIENKRLLQTLAAHGIAVP
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEE
VIDRERFFGYLERCIRTGLLPAPDLRQTSIGIR
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]