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The map label for this gene is galE [H]

Identifier: 159898295

GI number: 159898295

Start: 2060248

End: 2061234

Strand: Direct

Name: galE [H]

Synonym: Haur_1771

Alternate gene names: 159898295

Gene position: 2060248-2061234 (Clockwise)

Preceding gene: 159898292

Following gene: 159898296

Centisome position: 32.46

GC content: 53.39

Gene sequence:

>987_bases
ATGCGTATTTTGGTCTCCGGTGGCGCTGGCTATATTGGCAGCGTAACCAGTGCCGCATTGCTAGATGCTGGCTACGACGT
TGTAATCTTTGATAATTTGCGCCAAGGCCATCGCCAAGCGGTTCCCGCCGCTGCGACCTTTGTCTTGGGCGATCTGAATA
ATATTGCTGAAATTCGCAGTGCTTTTGAAGCTCATGGCCCTTTCGATGGGATTTTAAATTTTGCTTCGCATACCTTGGTT
GGCGAGTCGATGCAGCACCCTGAATATTATCTGCGCGATAGCGTGGTGGCGGGGATTAATTTGCTGACGGTTGCCGCTGA
ACATGGCGTGAAGGCTTTTATTCTCTCATCAACCGCCAACCTCTTCGACGACCCCGCTAAAATGCCAATCGACGAAAACG
AGCGAATTGTGCCAGGCTCGCCTTATGGTGAGATGAAATCGTGGATGGAGCGGGCGCTCTATTGGTATGAACGCGTGCAT
GGCATTCGCTATGGTGCGCTGCGCTATTTCAATGCCTGTGGTTGTACGCCGACGATTGGCGAACATCACGACCCTGAAAC
CCACTTGATTCCGTTGGTTTTGCAAGTTGCCTTGGGCCAGCGCGAATCGATTGCGATCTTCGGCGACGATTATCCAACCC
CCGATGGCTCGTGTGTGCGCGACTATGTGCATGTGAGCGATTTGGCCTCGGCGCATATTCTGACCTTGCAAGCCTTGCTC
AATGGCGGAGCCAGCCGTCGCTACAATTTAGGCAATGGTGGTGGTTTCAGCGTCAAAGAAGTTATCCAAGCAGTGCGCAA
TGTGACTGGCCATGCGATTCCAGCGGTGGTTGCGCCGCGCCGCGCTGGCGATCCGGCGACCTTGGTTGCTTCATCGGAAA
CGATTCGCCGCGAGTTGGGCTGGGAGCCACGCTATGCCACAATTGAGAGTATCATCGAAAGTGCTTGGGCTTGGCATCAA
CAACATCCTCACGGCTATAGCAAATAA

Upstream 100 bases:

>100_bases
CACGTGATCAGACTTCTCACCCACAATTAAGCTGATTCGGCTACAATAGCCAGCGAATTCGATGCTACACGACGATCTTG
CCGTGTAAAAAGGAGTTTGT

Downstream 100 bases:

>100_bases
AATTTGCTTCAAGGAGCAGCATTGATGGTTTCAACGACGCAACCAGCCTTTCAAGATCAATTGCAGGGCAATCATTGTTG
GGGCTGTGGCAAGGATAATC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MRILVSGGAGYIGSVTSAALLDAGYDVVIFDNLRQGHRQAVPAAATFVLGDLNNIAEIRSAFEAHGPFDGILNFASHTLV
GESMQHPEYYLRDSVVAGINLLTVAAEHGVKAFILSSTANLFDDPAKMPIDENERIVPGSPYGEMKSWMERALYWYERVH
GIRYGALRYFNACGCTPTIGEHHDPETHLIPLVLQVALGQRESIAIFGDDYPTPDGSCVRDYVHVSDLASAHILTLQALL
NGGASRRYNLGNGGGFSVKEVIQAVRNVTGHAIPAVVAPRRAGDPATLVASSETIRRELGWEPRYATIESIIESAWAWHQ
QHPHGYSK

Sequences:

>Translated_328_residues
MRILVSGGAGYIGSVTSAALLDAGYDVVIFDNLRQGHRQAVPAAATFVLGDLNNIAEIRSAFEAHGPFDGILNFASHTLV
GESMQHPEYYLRDSVVAGINLLTVAAEHGVKAFILSSTANLFDDPAKMPIDENERIVPGSPYGEMKSWMERALYWYERVH
GIRYGALRYFNACGCTPTIGEHHDPETHLIPLVLQVALGQRESIAIFGDDYPTPDGSCVRDYVHVSDLASAHILTLQALL
NGGASRRYNLGNGGGFSVKEVIQAVRNVTGHAIPAVVAPRRAGDPATLVASSETIRRELGWEPRYATIESIIESAWAWHQ
QHPHGYSK
>Mature_328_residues
MRILVSGGAGYIGSVTSAALLDAGYDVVIFDNLRQGHRQAVPAAATFVLGDLNNIAEIRSAFEAHGPFDGILNFASHTLV
GESMQHPEYYLRDSVVAGINLLTVAAEHGVKAFILSSTANLFDDPAKMPIDENERIVPGSPYGEMKSWMERALYWYERVH
GIRYGALRYFNACGCTPTIGEHHDPETHLIPLVLQVALGQRESIAIFGDDYPTPDGSCVRDYVHVSDLASAHILTLQALL
NGGASRRYNLGNGGGFSVKEVIQAVRNVTGHAIPAVVAPRRAGDPATLVASSETIRRELGWEPRYATIESIIESAWAWHQ
QHPHGYSK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=347, Percent_Identity=36.3112391930836, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI56118217, Length=347, Percent_Identity=36.3112391930836, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI189083684, Length=347, Percent_Identity=36.3112391930836, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI42516563, Length=307, Percent_Identity=27.0358306188925, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1786974, Length=338, Percent_Identity=38.4615384615385, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=25.214899713467, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=350, Percent_Identity=33.7142857142857, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71982038, Length=352, Percent_Identity=33.5227272727273, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17539532, Length=326, Percent_Identity=23.9263803680982, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=346, Percent_Identity=36.4161849710983, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI19923002, Length=346, Percent_Identity=34.393063583815, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=25.7142857142857, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35714; Mature: 35714

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVSGGAGYIGSVTSAALLDAGYDVVIFDNLRQGHRQAVPAAATFVLGDLNNIAEIRS
CEEEEECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCHHHHHHHHCHHHHHHHHH
AFEAHGPFDGILNFASHTLVGESMQHPEYYLRDSVVAGINLLTVAAEHGVKAFILSSTAN
HHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEHHHHCCCEEEEEECCHH
LFDDPAKMPIDENERIVPGSPYGEMKSWMERALYWYERVHGIRYGALRYFNACGCTPTIG
HHCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
EHHDPETHLIPLVLQVALGQRESIAIFGDDYPTPDGSCVRDYVHVSDLASAHILTLQALL
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NGGASRRYNLGNGGGFSVKEVIQAVRNVTGHAIPAVVAPRRAGDPATLVASSETIRRELG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEECHHHHHHHCC
WEPRYATIESIIESAWAWHQQHPHGYSK
CCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRILVSGGAGYIGSVTSAALLDAGYDVVIFDNLRQGHRQAVPAAATFVLGDLNNIAEIRS
CEEEEECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCHHHHHHHHCHHHHHHHHH
AFEAHGPFDGILNFASHTLVGESMQHPEYYLRDSVVAGINLLTVAAEHGVKAFILSSTAN
HHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEHHHHCCCEEEEEECCHH
LFDDPAKMPIDENERIVPGSPYGEMKSWMERALYWYERVHGIRYGALRYFNACGCTPTIG
HHCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
EHHDPETHLIPLVLQVALGQRESIAIFGDDYPTPDGSCVRDYVHVSDLASAHILTLQALL
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
NGGASRRYNLGNGGGFSVKEVIQAVRNVTGHAIPAVVAPRRAGDPATLVASSETIRRELG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEECHHHHHHHCC
WEPRYATIESIIESAWAWHQQHPHGYSK
CCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]