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The map label for this gene is yfhA [H]

Identifier: 159898260

GI number: 159898260

Start: 2022207

End: 2023262

Strand: Direct

Name: yfhA [H]

Synonym: Haur_1736

Alternate gene names: 159898260

Gene position: 2022207-2023262 (Clockwise)

Preceding gene: 159898259

Following gene: 159898261

Centisome position: 31.86

GC content: 55.87

Gene sequence:

>1056_bases
ATGAACACTTTTCCATGGATTACGATTCGCCCTAAGTTTGGCAAGTTTTCGCTGCGAATCGACCGCCGTTTGCCCAAGGT
TGCGCTGATTATCGCGCTGCTGGTGATGGCAATTATGGTGGTCAACATGGGCGTTGGTCAATATGAAATTAGCCCGCTCG
ATGTAGTTAAAACCTTGCTCGGCATGGAAACTGGCGATCCGCAGCATGTGCTGATTGTGCGCACCCTGCGCTTGCCACGC
ATGCTGCTTTCGGCTTTGGTTGGTTTGGCGCTGGGCACGTCGGGCGCATTGTTGCAAGGCTTGACCCGCAATCCCTTGGC
CGACCCCAGCATTATGGGCATCAACACGGGCGCTGGCCTAGTGGCAGTGGTATTGACAATTTTGGTACGCGATTTTCCAG
CGCGTTGGATTCCAGTCGCGGCCTTTGCTGGGGCGCTAGTCGCAGCAGTCTTGATGTATGTCTTGGCTTGGCGCAAGGGT
GGCGATTCGCCGATGCGCTTGGTGTTAATTGGGGTTGGCTTGAGTGCGGTTGGTTCCGCTGTCACAACCCTCGTGATCAC
GATTGGCAATATTTACGATGTGCAACGCGCTATGATCTGGCTGACGGGCAGCGTTTATGGCCGCTCGTGGGTCGATTTTT
GGGCCTTTGCGCCGTGGGTTGCGCTTGCTGTGCCGTTAGCCTGGTTTCAAGCTCGCCAACTCAATAGCCTGCATCTTGGT
GAAGATGTGGCCTTGGGCTTAGGTGTCAATGTTGGTCGCCAACGCGCTTGGATTTTATTCATAGCCGTGGCCTTGGCTGG
TGCCAGCGTCGCCGTAGCGGGTGTGATCAGCTTTGTGGGCTTGATTGCGCCGCACGTTGCGCGACGGTTGGTTGGTACCG
ATCACACTGGGCTTGTGCCAACCGCAGGTATGCTTGGCGCGTTGCTGCTAGTCGCTTCCGACTGGATTGGCCGCACGATT
GCCGCGCCCAACGAAATTCCTTGTGGCTTGGTCACCGCTGTGATTGGCGTACCGTTCTTTTTGGCAATGCTCTACCAACA
TGCCCGAACAAAGTGA

Upstream 100 bases:

>100_bases
GGCGGGTGATTGTGCGCCCGATGGAAGTTCCGGTTGGTGTAGTAACCGCGCTACTCGGCGGCCCAATGTTTATCTACCTT
GTACGCTGGCGGGTGCAACG

Downstream 100 bases:

>100_bases
GGATGTGATGTTAGCGACCGATACATTAACCTTGGGCTACGACGGCCCCAACATTCTCGATCAGTTGTCGATCACGCTGC
CTGCTGGGCAGATCACCGCT

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNTFPWITIRPKFGKFSLRIDRRLPKVALIIALLVMAIMVVNMGVGQYEISPLDVVKTLLGMETGDPQHVLIVRTLRLPR
MLLSALVGLALGTSGALLQGLTRNPLADPSIMGINTGAGLVAVVLTILVRDFPARWIPVAAFAGALVAAVLMYVLAWRKG
GDSPMRLVLIGVGLSAVGSAVTTLVITIGNIYDVQRAMIWLTGSVYGRSWVDFWAFAPWVALAVPLAWFQARQLNSLHLG
EDVALGLGVNVGRQRAWILFIAVALAGASVAVAGVISFVGLIAPHVARRLVGTDHTGLVPTAGMLGALLLVASDWIGRTI
AAPNEIPCGLVTAVIGVPFFLAMLYQHARTK

Sequences:

>Translated_351_residues
MNTFPWITIRPKFGKFSLRIDRRLPKVALIIALLVMAIMVVNMGVGQYEISPLDVVKTLLGMETGDPQHVLIVRTLRLPR
MLLSALVGLALGTSGALLQGLTRNPLADPSIMGINTGAGLVAVVLTILVRDFPARWIPVAAFAGALVAAVLMYVLAWRKG
GDSPMRLVLIGVGLSAVGSAVTTLVITIGNIYDVQRAMIWLTGSVYGRSWVDFWAFAPWVALAVPLAWFQARQLNSLHLG
EDVALGLGVNVGRQRAWILFIAVALAGASVAVAGVISFVGLIAPHVARRLVGTDHTGLVPTAGMLGALLLVASDWIGRTI
AAPNEIPCGLVTAVIGVPFFLAMLYQHARTK
>Mature_351_residues
MNTFPWITIRPKFGKFSLRIDRRLPKVALIIALLVMAIMVVNMGVGQYEISPLDVVKTLLGMETGDPQHVLIVRTLRLPR
MLLSALVGLALGTSGALLQGLTRNPLADPSIMGINTGAGLVAVVLTILVRDFPARWIPVAAFAGALVAAVLMYVLAWRKG
GDSPMRLVLIGVGLSAVGSAVTTLVITIGNIYDVQRAMIWLTGSVYGRSWVDFWAFAPWVALAVPLAWFQARQLNSLHLG
EDVALGLGVNVGRQRAWILFIAVALAGASVAVAGVISFVGLIAPHVARRLVGTDHTGLVPTAGMLGALLLVASDWIGRTI
AAPNEIPCGLVTAVIGVPFFLAMLYQHARTK

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=325, Percent_Identity=38.7692307692308, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1786804, Length=337, Percent_Identity=35.6083086053413, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790741, Length=301, Percent_Identity=36.5448504983389, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786805, Length=288, Percent_Identity=38.5416666666667, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788004, Length=307, Percent_Identity=35.5048859934853, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=32.3636363636364, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37357; Mature: 37357

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFPWITIRPKFGKFSLRIDRRLPKVALIIALLVMAIMVVNMGVGQYEISPLDVVKTLL
CCCCCEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHH
GMETGDPQHVLIVRTLRLPRMLLSALVGLALGTSGALLQGLTRNPLADPSIMGINTGAGL
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEECCCHHH
VAVVLTILVRDFPARWIPVAAFAGALVAAVLMYVLAWRKGGDSPMRLVLIGVGLSAVGSA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHH
VTTLVITIGNIYDVQRAMIWLTGSVYGRSWVDFWAFAPWVALAVPLAWFQARQLNSLHLG
HHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EDVALGLGVNVGRQRAWILFIAVALAGASVAVAGVISFVGLIAPHVARRLVGTDHTGLVP
CCCEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TAGMLGALLLVASDWIGRTIAAPNEIPCGLVTAVIGVPFFLAMLYQHARTK
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTFPWITIRPKFGKFSLRIDRRLPKVALIIALLVMAIMVVNMGVGQYEISPLDVVKTLL
CCCCCEEEECCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHH
GMETGDPQHVLIVRTLRLPRMLLSALVGLALGTSGALLQGLTRNPLADPSIMGINTGAGL
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEECCCHHH
VAVVLTILVRDFPARWIPVAAFAGALVAAVLMYVLAWRKGGDSPMRLVLIGVGLSAVGSA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHH
VTTLVITIGNIYDVQRAMIWLTGSVYGRSWVDFWAFAPWVALAVPLAWFQARQLNSLHLG
HHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EDVALGLGVNVGRQRAWILFIAVALAGASVAVAGVISFVGLIAPHVARRLVGTDHTGLVP
CCCEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TAGMLGALLLVASDWIGRTIAAPNEIPCGLVTAVIGVPFFLAMLYQHARTK
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]