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The map label for this gene is ycsN [H]

Identifier: 159898207

GI number: 159898207

Start: 1958463

End: 1959443

Strand: Direct

Name: ycsN [H]

Synonym: Haur_1683

Alternate gene names: 159898207

Gene position: 1958463-1959443 (Clockwise)

Preceding gene: 159898203

Following gene: 159898208

Centisome position: 30.86

GC content: 47.6

Gene sequence:

>981_bases
ATGCTGAAAACCCCACTCTATACCATTTCACGCACCGATCTCCAGATGGCTCCGATTGGCTATGGATGTATGACGATTGG
TGGGAATTGGAGCACTGAACCGTGGACTAGTAGCGAGTATGAGATCGGTCGCAAGGCCTTAGCGGCGGCACTTGAACAAT
CAATTACGTTGTTTGATCATGCTGATATTTATACCCGTGGTAAATCCGAACGGCTCTTTGGTGAACTTTTAGCCGAACAA
CCAAGCCTACGCCAGCAGATTGTTTTACAATCGAAGTGTGGTATTCGCTTTGCTGATGAGCCGCCTGGCTCGCCGCAACG
CTATGATTTTAGCTATGAGCACATTATTACATCGGTTGAAGGCAGCCTCAAACGCCTGAATACCGATCATCTTGACCTTT
TGCTTTTACATCGACCCGATATGTTAGTGGAGCCAGAAGAAATTGCGCAAGCCTTTGATCAATTGCAGCAGAGTGGCAAA
GTTCGTTATTTTGGGGTTAGTAATCACTCTCCAGCCCAAATCGATTTAATTCAGGCTGCGCTCGATCAACCATTGGTGGT
TAATCAAGTGCAACTGAGTTTGCTGCACCATCAGTTGATTAGCGAAGGCATTGATACCAATCGTAGCAACTTGCCGTTTA
ATGCGGCCTTTGGCTTATTGGATTATTGTCGCCTGCACAAAATTCAAATTCAGGCATGGGGACCATTGTCGGCTGGGCAG
CTCGTTAATTTCAATGACGATGCACCAGCGAATGTTAAAGCTACTGCTGCACTGGTAAATCAGCTGGCTGAACAGTATGA
CGTAAGCTCGGAAGCGATCCAGTTGGCCTGGTTGCTACGTCATCCGGCCCAAATTTTGCCGATTATTGGCACAACCAATC
CAGGCCGAATTGCTGCTACCAAACAAGCCTTGCAAATCGAACTCAGTCGTGAAGAATGGTATCATCTGTTGGCCGCCGCT
CGCACTGCGAATGTGCCATAG

Upstream 100 bases:

>100_bases
GTAAACAATGAAGAAATAATGAAGACATTTCGGCGATTAAAAGTATGTTACCCTAAACCTGGGCTGAAGCCTGCCCAAGG
TTTTGGATAGTGAGGATAGT

Downstream 100 bases:

>100_bases
CTTGGTAATTGACATAACCTTTTGTAACACCTGTGTAACATGACCTCGCTAAACTCAGCCTATCTAAAATGCTGATTGTT
TAGCGAGGTTTTGCATGCGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLKTPLYTISRTDLQMAPIGYGCMTIGGNWSTEPWTSSEYEIGRKALAAALEQSITLFDHADIYTRGKSERLFGELLAEQ
PSLRQQIVLQSKCGIRFADEPPGSPQRYDFSYEHIITSVEGSLKRLNTDHLDLLLLHRPDMLVEPEEIAQAFDQLQQSGK
VRYFGVSNHSPAQIDLIQAALDQPLVVNQVQLSLLHHQLISEGIDTNRSNLPFNAAFGLLDYCRLHKIQIQAWGPLSAGQ
LVNFNDDAPANVKATAALVNQLAEQYDVSSEAIQLAWLLRHPAQILPIIGTTNPGRIAATKQALQIELSREEWYHLLAAA
RTANVP

Sequences:

>Translated_326_residues
MLKTPLYTISRTDLQMAPIGYGCMTIGGNWSTEPWTSSEYEIGRKALAAALEQSITLFDHADIYTRGKSERLFGELLAEQ
PSLRQQIVLQSKCGIRFADEPPGSPQRYDFSYEHIITSVEGSLKRLNTDHLDLLLLHRPDMLVEPEEIAQAFDQLQQSGK
VRYFGVSNHSPAQIDLIQAALDQPLVVNQVQLSLLHHQLISEGIDTNRSNLPFNAAFGLLDYCRLHKIQIQAWGPLSAGQ
LVNFNDDAPANVKATAALVNQLAEQYDVSSEAIQLAWLLRHPAQILPIIGTTNPGRIAATKQALQIELSREEWYHLLAAA
RTANVP
>Mature_326_residues
MLKTPLYTISRTDLQMAPIGYGCMTIGGNWSTEPWTSSEYEIGRKALAAALEQSITLFDHADIYTRGKSERLFGELLAEQ
PSLRQQIVLQSKCGIRFADEPPGSPQRYDFSYEHIITSVEGSLKRLNTDHLDLLLLHRPDMLVEPEEIAQAFDQLQQSGK
VRYFGVSNHSPAQIDLIQAALDQPLVVNQVQLSLLHHQLISEGIDTNRSNLPFNAAFGLLDYCRLHKIQIQAWGPLSAGQ
LVNFNDDAPANVKATAALVNQLAEQYDVSSEAIQLAWLLRHPAQILPIIGTTNPGRIAATKQALQIELSREEWYHLLAAA
RTANVP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436966, Length=331, Percent_Identity=22.9607250755287, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI27436962, Length=325, Percent_Identity=22.4615384615385, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI27436964, Length=327, Percent_Identity=22.9357798165138, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI27436969, Length=328, Percent_Identity=21.6463414634146, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4504825, Length=328, Percent_Identity=21.6463414634146, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=22.2910216718266, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI48994888, Length=302, Percent_Identity=37.7483443708609, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=27.7777777777778, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788081, Length=302, Percent_Identity=28.8079470198675, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788070, Length=337, Percent_Identity=26.7062314540059, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789375, Length=280, Percent_Identity=28.9285714285714, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=24.7159090909091, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17552492, Length=299, Percent_Identity=23.7458193979933, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=345, Percent_Identity=24.9275362318841, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320079, Length=267, Percent_Identity=27.3408239700375, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323998, Length=337, Percent_Identity=25.2225519287834, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36285; Mature: 36285

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTPLYTISRTDLQMAPIGYGCMTIGGNWSTEPWTSSEYEIGRKALAAALEQSITLFDH
CCCCCCEEEECCCEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEC
ADIYTRGKSERLFGELLAEQPSLRQQIVLQSKCGIRFADEPPGSPQRYDFSYEHIITSVE
CHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHH
GSLKRLNTDHLDLLLLHRPDMLVEPEEIAQAFDQLQQSGKVRYFGVSNHSPAQIDLIQAA
HHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
LDQPLVVNQVQLSLLHHQLISEGIDTNRSNLPFNAAFGLLDYCRLHKIQIQAWGPLSAGQ
HCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
LVNFNDDAPANVKATAALVNQLAEQYDVSSEAIQLAWLLRHPAQILPIIGTTNPGRIAAT
EEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEE
KQALQIELSREEWYHLLAAARTANVP
EEEEEEEECHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKTPLYTISRTDLQMAPIGYGCMTIGGNWSTEPWTSSEYEIGRKALAAALEQSITLFDH
CCCCCCEEEECCCEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEC
ADIYTRGKSERLFGELLAEQPSLRQQIVLQSKCGIRFADEPPGSPQRYDFSYEHIITSVE
CHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHH
GSLKRLNTDHLDLLLLHRPDMLVEPEEIAQAFDQLQQSGKVRYFGVSNHSPAQIDLIQAA
HHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
LDQPLVVNQVQLSLLHHQLISEGIDTNRSNLPFNAAFGLLDYCRLHKIQIQAWGPLSAGQ
HCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
LVNFNDDAPANVKATAALVNQLAEQYDVSSEAIQLAWLLRHPAQILPIIGTTNPGRIAAT
EEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEE
KQALQIELSREEWYHLLAAARTANVP
EEEEEEEECHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]