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The map label for this gene is cyaB [H]

Identifier: 159898134

GI number: 159898134

Start: 1870242

End: 1871828

Strand: Direct

Name: cyaB [H]

Synonym: Haur_1610

Alternate gene names: 159898134

Gene position: 1870242-1871828 (Clockwise)

Preceding gene: 159898133

Following gene: 159898135

Centisome position: 29.47

GC content: 51.86

Gene sequence:

>1587_bases
ATGCCCGAACAACTACACCATGAACTCTCGTTATGCCATCGAGAGCTACGGGCGATCTACGACCTCGATGCGCTCCGCGA
TACAACCGACTCGACCGAAACCTTTTTAACTGGCTGTGCCGCAATTATTCGTGGGGTGTTGCAGCCCGATTTGCTGCAAT
TAATTACCCTTGATTTGGAAGATTGCCCCGCCCAAAATATTACAATTGAACGCTGGCGGCCACAGGATGCTGCTAGTTTG
ATGCTGGCCCTGACTAATGCGTTGGCTGGCGGCGAAACCTCAACCTTGCAAGAGGGCGATTCAGAAATTATTGTGCGTTC
GCTCTCGGTTAAGGGTGAGCGGCTGGGTGTGTTGGTGCTTGGCTCGGCTGATCACCATTGGTCGGCTGATAATCGGCGTT
TGATGGATGCTATGTGTTCGCAAATCGATTCGGCCATGGCTGGCTTGCGCCTATTCCAACAAGTGCAATCGCGCAACCGC
GAACTCGAAACGATCTATCGTTTGGATCGCTTGATCGATGCCACGCCCGATTTCGATCAAGGTTTGGGAGCAGCATTGGG
CTTGCTCTCCGAGACGATTGGCGCTGCTTGGAGCTTTATTATGCTCTACACCGCCGAGGAGCATGAGCTTGAATTTCGTG
CCGCTTCGCACGCTGATGTGGCCGACCCGTGCACTGAAGTGTCGCAAGTCTTGCGCGATTTGGCCCGCCAAACCGTTGAT
CAAGGCAAATTGGTGCGCCGCGAACAGATCGATCAAACAATTGGAGCCTATATCGGCGTGCCCTTGATTTTGAAAAATCA
AATTATTGGGGTTTTTGGTGGGGCGAATCCGCCAGGCACACGTGGTTTTAGCATTCACGAAGTTAAAATGCTGAACGCAA
TTGCTTCGCAAATGGATACGGCGCTGTTTGAAGATCGCCAACAACGCCATATTCGCGAAACGTTTGCCCGCTATGTCAGC
CCCGATGTAGTCGATTTGATGTTGCGCACGCCTGGCAATGATTATCTGAATGTGCATCGTCAACAATTATCGATGCTTTT
TTCCGATATGCGCGGCTTTACCACGGTTTCCGAACAATTGCCTGCCGATGTGGTTGCTCGCATGCTCAACGAACATCTCT
CGGCCATGACCACGATTATTCGCAATGCAGGTGGCACGGTCGATAAATTTGTGGGCGATGAAATTGTGGCCTTTTTTGGT
GCGCCCTTGCCCTATGAGCAACACCCTTTGTTGGCGGTGCAAACTGGCTTGTTGATGCAGGCCCGTCATAACGAATTGAT
GACCGAATGGCAGAAGCAAGGCTTGCCAGCAGTGGCAATTGGCATTGGGATTGCCTCAGGCGAGGTGGTCGTGGGCAATA
TCGGCTCGTCGCAAATGATGAATTACACCGCGATTGGCTCGGATATGAATTTAGCAGCCCGCTTGTGTAGTGCCGCGTTG
CCCAACCAAATTTTGGTCAGCCAAGCCACCTATGATGCGGTGCGTGAGCAAGTTCAGGCTGTGCCAGTGGCCCCATTGAG
CTTGCGGCATATTTCGCAATTAGTGCAAGCCTACAGTATTGAAGCAGTGCTGAGTACTCAAGCCTAA

Upstream 100 bases:

>100_bases
TGGTGCTGTCGCCCTTTTTTGTGCTATTCCGGCGCTGGCAGTTCATGCTATACTGGCGTTGTTAATCCACGTTTTGCTGG
CTCAAGGAGGTGCTGCGCGT

Downstream 100 bases:

>100_bases
GCGCAGCTTGGGACTGCTGTAACTTTGGATGTAGTGACGATCACGAGATCTATATTTAGGGGGTGCAGGGGGATTAAAGC
CCCCTGCGTTTCCCTCCGGC

Product: GAF sensor-containing adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MPEQLHHELSLCHRELRAIYDLDALRDTTDSTETFLTGCAAIIRGVLQPDLLQLITLDLEDCPAQNITIERWRPQDAASL
MLALTNALAGGETSTLQEGDSEIIVRSLSVKGERLGVLVLGSADHHWSADNRRLMDAMCSQIDSAMAGLRLFQQVQSRNR
ELETIYRLDRLIDATPDFDQGLGAALGLLSETIGAAWSFIMLYTAEEHELEFRAASHADVADPCTEVSQVLRDLARQTVD
QGKLVRREQIDQTIGAYIGVPLILKNQIIGVFGGANPPGTRGFSIHEVKMLNAIASQMDTALFEDRQQRHIRETFARYVS
PDVVDLMLRTPGNDYLNVHRQQLSMLFSDMRGFTTVSEQLPADVVARMLNEHLSAMTTIIRNAGGTVDKFVGDEIVAFFG
APLPYEQHPLLAVQTGLLMQARHNELMTEWQKQGLPAVAIGIGIASGEVVVGNIGSSQMMNYTAIGSDMNLAARLCSAAL
PNQILVSQATYDAVREQVQAVPVAPLSLRHISQLVQAYSIEAVLSTQA

Sequences:

>Translated_528_residues
MPEQLHHELSLCHRELRAIYDLDALRDTTDSTETFLTGCAAIIRGVLQPDLLQLITLDLEDCPAQNITIERWRPQDAASL
MLALTNALAGGETSTLQEGDSEIIVRSLSVKGERLGVLVLGSADHHWSADNRRLMDAMCSQIDSAMAGLRLFQQVQSRNR
ELETIYRLDRLIDATPDFDQGLGAALGLLSETIGAAWSFIMLYTAEEHELEFRAASHADVADPCTEVSQVLRDLARQTVD
QGKLVRREQIDQTIGAYIGVPLILKNQIIGVFGGANPPGTRGFSIHEVKMLNAIASQMDTALFEDRQQRHIRETFARYVS
PDVVDLMLRTPGNDYLNVHRQQLSMLFSDMRGFTTVSEQLPADVVARMLNEHLSAMTTIIRNAGGTVDKFVGDEIVAFFG
APLPYEQHPLLAVQTGLLMQARHNELMTEWQKQGLPAVAIGIGIASGEVVVGNIGSSQMMNYTAIGSDMNLAARLCSAAL
PNQILVSQATYDAVREQVQAVPVAPLSLRHISQLVQAYSIEAVLSTQA
>Mature_527_residues
PEQLHHELSLCHRELRAIYDLDALRDTTDSTETFLTGCAAIIRGVLQPDLLQLITLDLEDCPAQNITIERWRPQDAASLM
LALTNALAGGETSTLQEGDSEIIVRSLSVKGERLGVLVLGSADHHWSADNRRLMDAMCSQIDSAMAGLRLFQQVQSRNRE
LETIYRLDRLIDATPDFDQGLGAALGLLSETIGAAWSFIMLYTAEEHELEFRAASHADVADPCTEVSQVLRDLARQTVDQ
GKLVRREQIDQTIGAYIGVPLILKNQIIGVFGGANPPGTRGFSIHEVKMLNAIASQMDTALFEDRQQRHIRETFARYVSP
DVVDLMLRTPGNDYLNVHRQQLSMLFSDMRGFTTVSEQLPADVVARMLNEHLSAMTTIIRNAGGTVDKFVGDEIVAFFGA
PLPYEQHPLLAVQTGLLMQARHNELMTEWQKQGLPAVAIGIGIASGEVVVGNIGSSQMMNYTAIGSDMNLAARLCSAALP
NQILVSQATYDAVREQVQAVPVAPLSLRHISQLVQAYSIEAVLSTQA

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI4557257, Length=196, Percent_Identity=27.0408163265306, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 57979; Mature: 57848

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEQLHHELSLCHRELRAIYDLDALRDTTDSTETFLTGCAAIIRGVLQPDLLQLITLDLE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCHH
DCPAQNITIERWRPQDAASLMLALTNALAGGETSTLQEGDSEIIVRSLSVKGERLGVLVL
CCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHCCCCEEEEEEE
GSADHHWSADNRRLMDAMCSQIDSAMAGLRLFQQVQSRNRELETIYRLDRLIDATPDFDQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHH
GLGAALGLLSETIGAAWSFIMLYTAEEHELEFRAASHADVADPCTEVSQVLRDLARQTVD
HHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
QGKLVRREQIDQTIGAYIGVPLILKNQIIGVFGGANPPGTRGFSIHEVKMLNAIASQMDT
HHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
ALFEDRQQRHIRETFARYVSPDVVDLMLRTPGNDYLNVHRQQLSMLFSDMRGFTTVSEQL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHC
PADVVARMLNEHLSAMTTIIRNAGGTVDKFVGDEIVAFFGAPLPYEQHPLLAVQTGLLMQ
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ARHNELMTEWQKQGLPAVAIGIGIASGEVVVGNIGSSQMMNYTAIGSDMNLAARLCSAAL
HHHHHHHHHHHHCCCCEEEEEEEEECCCEEEECCCCHHHCCCEECCCCHHHHHHHHHHHC
PNQILVSQATYDAVREQVQAVPVAPLSLRHISQLVQAYSIEAVLSTQA
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PEQLHHELSLCHRELRAIYDLDALRDTTDSTETFLTGCAAIIRGVLQPDLLQLITLDLE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCHH
DCPAQNITIERWRPQDAASLMLALTNALAGGETSTLQEGDSEIIVRSLSVKGERLGVLVL
CCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHCCCCEEEEEEE
GSADHHWSADNRRLMDAMCSQIDSAMAGLRLFQQVQSRNRELETIYRLDRLIDATPDFDQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHH
GLGAALGLLSETIGAAWSFIMLYTAEEHELEFRAASHADVADPCTEVSQVLRDLARQTVD
HHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
QGKLVRREQIDQTIGAYIGVPLILKNQIIGVFGGANPPGTRGFSIHEVKMLNAIASQMDT
HHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
ALFEDRQQRHIRETFARYVSPDVVDLMLRTPGNDYLNVHRQQLSMLFSDMRGFTTVSEQL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHC
PADVVARMLNEHLSAMTTIIRNAGGTVDKFVGDEIVAFFGAPLPYEQHPLLAVQTGLLMQ
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ARHNELMTEWQKQGLPAVAIGIGIASGEVVVGNIGSSQMMNYTAIGSDMNLAARLCSAAL
HHHHHHHHHHHHCCCCEEEEEEEEECCCEEEECCCCHHHCCCEECCCCHHHHHHHHHHHC
PNQILVSQATYDAVREQVQAVPVAPLSLRHISQLVQAYSIEAVLSTQA
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]