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The map label for this gene is thrC [H]

Identifier: 159898092

GI number: 159898092

Start: 1819874

End: 1820866

Strand: Direct

Name: thrC [H]

Synonym: Haur_1568

Alternate gene names: 159898092

Gene position: 1819874-1820866 (Clockwise)

Preceding gene: 159898091

Following gene: 159898093

Centisome position: 28.67

GC content: 49.95

Gene sequence:

>993_bases
TTGATCAGACCACGTGGTCACTGTGGCGTTATAAATTTACCAGCCGTCTCAAGCATTATCTCATTAGGCGAAGGTTGTAC
TCCACTGACCAAGGTCAAGGTTGGTCGGCATAGCTTTCTTGCGAAACTTGAATTTCTTAATCCAACTGGTTCGTATAAAG
ATCGTGGTGTGTCGGTAATGATGAGTCATATCTTGAGTCATCAGGTTCGGCAAGTGATTGACGACTCTTCTGGCAATGCT
GGTGCTTCTATCTCGGCCTATGCGGCTCATGCCGGTATCCAAGCACGGATTTTTGTGCCGGCCCATGCTAGTAGTTATAA
AAAACAGCAAATTCAACGGTTTAATGCCACTTTAGTTGAAGTTGAAGGGTTACGGAGCGCGACGACCACCGCCTGTTGGA
AGGAAGCTCAGCATACAACCTATGCCAGCCATGCTTGGAGTCCTTTTTTTCTGGCGGGCCAAATGACCTGTGCTTGGGAG
ATGTGGGAACAACTTGGGAGGCGAGTACCCGCTGCCATTGTTTGTGTTGCCGGTCAAGGTGGCCTCTTAATTGGCTTATT
GCAGGGATTTAAGGCCTTGCTAAAAGCCAAGCTGATTCCACACCTACCGCGATTATATGCAGTTCAGGCGCGTGCCTGTG
ACCCAATTGTGCGAGCTTGGGAGGAAAGAAAGGAGTTTCCCCAGGCTTGTGTTGAACAGACAACCTTGGCCGAAGGAATT
CGGATTGCCCAACCAGTTCGTGGCCGCGATATTCTCCGCGCGATCTACGAATCAGCAGGTGCGGCTATTCGGGTAGAGGA
ACACGAAATTCTCGCTGCTCAAGCGATGTTGGCCCACCAAGGTTTATTAGTCGAGGCCACCAGTGCTGCTGCGGTCGCTG
GATTATCCCAAATTTGCCAATTAACCGAGCTTGCGCCCGACGATATTGTTATTCCGTTGACTGGCAGTGGCCTTAAACAA
GCCGCTGTAGCCGAATTAAGCATGAGGAGTTAA

Upstream 100 bases:

>100_bases
CAAGTGTGCTATACCGCCGCCAATTGTTTAAGTTGGCGTTGTCAACAGTGTGGAGGCACTTTAGGGATCGATACTATGCC
TAGTTTTGACCCTAGCCTGA

Downstream 100 bases:

>100_bases
GCACAACGATGGTAGCTAAAGATATGGATTGGACGGAAAATTATACGACGATCAAGGCTTTGGATGCTCGCCATGATGTT
TGGAAACACAATGCAGCGGT

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIRPRGHCGVINLPAVSSIISLGEGCTPLTKVKVGRHSFLAKLEFLNPTGSYKDRGVSVMMSHILSHQVRQVIDDSSGNA
GASISAYAAHAGIQARIFVPAHASSYKKQQIQRFNATLVEVEGLRSATTTACWKEAQHTTYASHAWSPFFLAGQMTCAWE
MWEQLGRRVPAAIVCVAGQGGLLIGLLQGFKALLKAKLIPHLPRLYAVQARACDPIVRAWEERKEFPQACVEQTTLAEGI
RIAQPVRGRDILRAIYESAGAAIRVEEHEILAAQAMLAHQGLLVEATSAAAVAGLSQICQLTELAPDDIVIPLTGSGLKQ
AAVAELSMRS

Sequences:

>Translated_330_residues
MIRPRGHCGVINLPAVSSIISLGEGCTPLTKVKVGRHSFLAKLEFLNPTGSYKDRGVSVMMSHILSHQVRQVIDDSSGNA
GASISAYAAHAGIQARIFVPAHASSYKKQQIQRFNATLVEVEGLRSATTTACWKEAQHTTYASHAWSPFFLAGQMTCAWE
MWEQLGRRVPAAIVCVAGQGGLLIGLLQGFKALLKAKLIPHLPRLYAVQARACDPIVRAWEERKEFPQACVEQTTLAEGI
RIAQPVRGRDILRAIYESAGAAIRVEEHEILAAQAMLAHQGLLVEATSAAAVAGLSQICQLTELAPDDIVIPLTGSGLKQ
AAVAELSMRS
>Mature_330_residues
MIRPRGHCGVINLPAVSSIISLGEGCTPLTKVKVGRHSFLAKLEFLNPTGSYKDRGVSVMMSHILSHQVRQVIDDSSGNA
GASISAYAAHAGIQARIFVPAHASSYKKQQIQRFNATLVEVEGLRSATTTACWKEAQHTTYASHAWSPFFLAGQMTCAWE
MWEQLGRRVPAAIVCVAGQGGLLIGLLQGFKALLKAKLIPHLPRLYAVQARACDPIVRAWEERKEFPQACVEQTTLAEGI
RIAQPVRGRDILRAIYESAGAAIRVEEHEILAAQAMLAHQGLLVEATSAAAVAGLSQICQLTELAPDDIVIPLTGSGLKQ
AAVAELSMRS

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=293, Percent_Identity=28.3276450511945, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 35519; Mature: 35519

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPRGHCGVINLPAVSSIISLGEGCTPLTKVKVGRHSFLAKLEFLNPTGSYKDRGVSVM
CCCCCCCCCEEECHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHEECCCCCCCCHHHHHHH
MSHILSHQVRQVIDDSSGNAGASISAYAAHAGIQARIFVPAHASSYKKQQIQRFNATLVE
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCEEE
VEGLRSATTTACWKEAQHTTYASHAWSPFFLAGQMTCAWEMWEQLGRRVPAAIVCVAGQG
ECCCCHHHHHHHHHHHHCCCHHHCCCCCEEECCCHHHHHHHHHHHHCCCCEEEEEEECCC
GLLIGLLQGFKALLKAKLIPHLPRLYAVQARACDPIVRAWEERKEFPQACVEQTTLAEGI
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RIAQPVRGRDILRAIYESAGAAIRVEEHEILAAQAMLAHQGLLVEATSAAAVAGLSQICQ
HHCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHH
LTELAPDDIVIPLTGSGLKQAAVAELSMRS
HHHCCCCCEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIRPRGHCGVINLPAVSSIISLGEGCTPLTKVKVGRHSFLAKLEFLNPTGSYKDRGVSVM
CCCCCCCCCEEECHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHEECCCCCCCCHHHHHHH
MSHILSHQVRQVIDDSSGNAGASISAYAAHAGIQARIFVPAHASSYKKQQIQRFNATLVE
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCEEE
VEGLRSATTTACWKEAQHTTYASHAWSPFFLAGQMTCAWEMWEQLGRRVPAAIVCVAGQG
ECCCCHHHHHHHHHHHHCCCHHHCCCCCEEECCCHHHHHHHHHHHHCCCCEEEEEEECCC
GLLIGLLQGFKALLKAKLIPHLPRLYAVQARACDPIVRAWEERKEFPQACVEQTTLAEGI
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RIAQPVRGRDILRAIYESAGAAIRVEEHEILAAQAMLAHQGLLVEATSAAAVAGLSQICQ
HHCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHH
LTELAPDDIVIPLTGSGLKQAAVAELSMRS
HHHCCCCCEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]