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The map label for this gene is aroB [H]

Identifier: 159898077

GI number: 159898077

Start: 1804427

End: 1805584

Strand: Direct

Name: aroB [H]

Synonym: Haur_1553

Alternate gene names: 159898077

Gene position: 1804427-1805584 (Clockwise)

Preceding gene: 159898076

Following gene: 159898078

Centisome position: 28.43

GC content: 52.16

Gene sequence:

>1158_bases
ATGGTTATGCGTTCGATCCTGCAAGCGTTTGAAGTACGCTATTCCTATCCGGTGCATTGTACGCACCGATTATTTGGCTT
GGATAACCCAATTCTCCATGAATTATTTGCGCCAAGCGCTAGTCTACCGAAGCTTTGGGTTGTGCTTGATCAGGCGGTGG
CTGAGCATCACCCCAATCTATTAACTGAAATTGCAGCCTATGCCCAAGCCAGCCAAGCCTTCAGCTTGGTTGAGCCAAGC
CTGATTTTGGCTGGTGGCGAAGCAATTAAGCAGACTACTGAGCCATTGCAAGCAGTCTACGATGGAATTAATCGCTATGC
GATCGATCGCCATTCGTATCTGATGGCAATTGGCGGCGGGGCGTTGATCGATATGGTTGGCTATGCAGCGGCGACGGCGC
ATCGCGGGGTGCGCTTAATTCGCGTGCCAACCACAGTTTTGGCCCAAAACGATGCAGCGGTTGGGGTTAAAAATAGCATC
AATGCCTTTGGCAAAAAGAATTTCTTGGGCACATTTGCTCCGCCTTATGCTGTGCTCAACGATAGCCATTTTCTCACGAC
GCTGAGTGAGCGCGATTGGCGCAGTGGCATCGCCGAGGCAATCAAGGTAGCTTTGCTCAAAGATCCCGCCTTTTTTGCCA
CGATTGAGCGTACTGCTGCGGCCTTGCGTCAGCGTGATTTAGCCGTAATGGAAGATCAGGTTTTTCGCTGTGCCGAGCTG
CATTTGGCCCACATCGCTGGTGGCGACCCGTTTGAGCGAGGCTCAGCGCGGCCCTTGGATTTTGGCCATTGGGCGGCGCA
TAAACTTGAACAGCTCAGCAATTATAGTTTGCGCCATGGCGAGGCGGTGGCAATTGGCATCGCCTTGGATTGCACCTACA
GCTATTTAAACGCTGATTTAGCCGAGGCCGATTGGCAACGGGTCTTGACTTGTCTAACCGCAGTTGGCTTCGAACTCTAT
CATCCTGCCCTGAGCAACCAGCTTGAACTGCCCGAACATCCCCAAAGTTTGCTGAGCGGCTTGGCCGAATTTCGCGAGCA
CCTTGGTGGCCAATTAACCATCACCTTAATGCGCGGCATCGGCCAACCCTACGATGTTCACACAATTGATCTACCGATGA
TGCAACAAGCCATTCGATATTTAGCCGAACGGGCTTAA

Upstream 100 bases:

>100_bases
CTGTTTGGCGCTCGCTAAATAACGCCGTACTACGAGCTATGCTAAAATTAGGATATTGTAATACGATTGATTGTTTGAGC
GGTTGCTCCTAGTTGTCGAG

Downstream 100 bases:

>100_bases
AGCGAGGATTTTATGCAGATTGAAGGCTCTTGCCCACGCACCCAGCGTGAGTTGATTGAACTGGAATTTATTGAGCATCG
CACCAAAATTTTAGATATCG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MVMRSILQAFEVRYSYPVHCTHRLFGLDNPILHELFAPSASLPKLWVVLDQAVAEHHPNLLTEIAAYAQASQAFSLVEPS
LILAGGEAIKQTTEPLQAVYDGINRYAIDRHSYLMAIGGGALIDMVGYAAATAHRGVRLIRVPTTVLAQNDAAVGVKNSI
NAFGKKNFLGTFAPPYAVLNDSHFLTTLSERDWRSGIAEAIKVALLKDPAFFATIERTAAALRQRDLAVMEDQVFRCAEL
HLAHIAGGDPFERGSARPLDFGHWAAHKLEQLSNYSLRHGEAVAIGIALDCTYSYLNADLAEADWQRVLTCLTAVGFELY
HPALSNQLELPEHPQSLLSGLAEFREHLGGQLTITLMRGIGQPYDVHTIDLPMMQQAIRYLAERA

Sequences:

>Translated_385_residues
MVMRSILQAFEVRYSYPVHCTHRLFGLDNPILHELFAPSASLPKLWVVLDQAVAEHHPNLLTEIAAYAQASQAFSLVEPS
LILAGGEAIKQTTEPLQAVYDGINRYAIDRHSYLMAIGGGALIDMVGYAAATAHRGVRLIRVPTTVLAQNDAAVGVKNSI
NAFGKKNFLGTFAPPYAVLNDSHFLTTLSERDWRSGIAEAIKVALLKDPAFFATIERTAAALRQRDLAVMEDQVFRCAEL
HLAHIAGGDPFERGSARPLDFGHWAAHKLEQLSNYSLRHGEAVAIGIALDCTYSYLNADLAEADWQRVLTCLTAVGFELY
HPALSNQLELPEHPQSLLSGLAEFREHLGGQLTITLMRGIGQPYDVHTIDLPMMQQAIRYLAERA
>Mature_385_residues
MVMRSILQAFEVRYSYPVHCTHRLFGLDNPILHELFAPSASLPKLWVVLDQAVAEHHPNLLTEIAAYAQASQAFSLVEPS
LILAGGEAIKQTTEPLQAVYDGINRYAIDRHSYLMAIGGGALIDMVGYAAATAHRGVRLIRVPTTVLAQNDAAVGVKNSI
NAFGKKNFLGTFAPPYAVLNDSHFLTTLSERDWRSGIAEAIKVALLKDPAFFATIERTAAALRQRDLAVMEDQVFRCAEL
HLAHIAGGDPFERGSARPLDFGHWAAHKLEQLSNYSLRHGEAVAIGIALDCTYSYLNADLAEADWQRVLTCLTAVGFELY
HPALSNQLELPEHPQSLLSGLAEFREHLGGQLTITLMRGIGQPYDVHTIDLPMMQQAIRYLAERA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=350, Percent_Identity=32.8571428571429, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320332, Length=285, Percent_Identity=28.0701754385965, Blast_Score=113, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 42374; Mature: 42374

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMRSILQAFEVRYSYPVHCTHRLFGLDNPILHELFAPSASLPKLWVVLDQAVAEHHPNL
CHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHH
LTEIAAYAQASQAFSLVEPSLILAGGEAIKQTTEPLQAVYDGINRYAIDRHSYLMAIGGG
HHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCC
ALIDMVGYAAATAHRGVRLIRVPTTVLAQNDAAVGVKNSINAFGKKNFLGTFAPPYAVLN
HHHHHHHHHHHHHHCCEEEEEECHHHEECCCCCCCCHHHHHHHCCCCCCCCCCCCHHEEC
DSHFLTTLSERDWRSGIAEAIKVALLKDPAFFATIERTAAALRQRDLAVMEDQVFRCAEL
CCHHEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLAHIAGGDPFERGSARPLDFGHWAAHKLEQLSNYSLRHGEAVAIGIALDCTYSYLNADL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEHHHHHHHCHH
AEADWQRVLTCLTAVGFELYHPALSNQLELPEHPQSLLSGLAEFREHLGGQLTITLMRGI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHC
GQPYDVHTIDLPMMQQAIRYLAERA
CCCCCEEEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVMRSILQAFEVRYSYPVHCTHRLFGLDNPILHELFAPSASLPKLWVVLDQAVAEHHPNL
CHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHH
LTEIAAYAQASQAFSLVEPSLILAGGEAIKQTTEPLQAVYDGINRYAIDRHSYLMAIGGG
HHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCC
ALIDMVGYAAATAHRGVRLIRVPTTVLAQNDAAVGVKNSINAFGKKNFLGTFAPPYAVLN
HHHHHHHHHHHHHHCCEEEEEECHHHEECCCCCCCCHHHHHHHCCCCCCCCCCCCHHEEC
DSHFLTTLSERDWRSGIAEAIKVALLKDPAFFATIERTAAALRQRDLAVMEDQVFRCAEL
CCHHEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLAHIAGGDPFERGSARPLDFGHWAAHKLEQLSNYSLRHGEAVAIGIALDCTYSYLNADL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEHHHHHHHCHH
AEADWQRVLTCLTAVGFELYHPALSNQLELPEHPQSLLSGLAEFREHLGGQLTITLMRGI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHC
GQPYDVHTIDLPMMQQAIRYLAERA
CCCCCEEEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA