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The map label for this gene is aes [C]

Identifier: 159898036

GI number: 159898036

Start: 1760977

End: 1762152

Strand: Direct

Name: aes [C]

Synonym: Haur_1511

Alternate gene names: 159898036

Gene position: 1760977-1762152 (Clockwise)

Preceding gene: 159898033

Following gene: 159898037

Centisome position: 27.75

GC content: 52.81

Gene sequence:

>1176_bases
GTGCGTCTAGCCTTAACCATCATTATTCTGCCGATTGTGCTGCTGGCCTTGGCAAGCGCCGCGATGTTGGTCTTGCCAGC
TCCCAATTTTATTTTTTTCCAGCTAGGAATTGCCGCCCAAGAATGGGCACCATGGTTTTTACTGGTCTTATTGGTTAGTC
TGGGGTTGTTGTTTGGCTTTGCGCCGCCCACTGGCTTGGCTCGTTTGCTCAATCGACTAGTTGGTTTTGGAGCGATGCTG
AGTTTTATTGTGATTGCTGGGATGTTGGTGCGTGGACTAATGACCGATCTGCGAGTGCGTTCGAATCAGCCGACGGTGGT
TGCAGCTGGGCCTGGTACATTTCGGCTTAGCCAATTTGCCTTGGGTGATCCTGCGCCGCAAGGCCTGCTGCGTGAGCAAA
ACACCGTTTATGCTGAGGTTGCAGGTGAATCGTTGTTGGTTGATGTGTATGTGCCGCCGACTGCGCCAGTCAATGCTCCA
GCCTTAATTGTGGTGCATGGTGGCTCATGGCGCGGTGGCACGAAAGGCGATATTCCTGCTTGGAATCGTTGGGCCGCTGG
TCAAGGCTATGTGGTATTTGATGTCAGCTATCGTTTAGCGCCCCAAGCTCAGTTTCCGGCAGCAGTCAGCGATGTTAAAT
GTGCAATTGGCTATGTGCGCCGCAACGCCGAGCAATTCGGGATCGATCCCCAGCGCTTGGGGTTGGTTGGGCGTTCAGCC
GGAGCACAATTGGTGCTGATTGCGGCCTATTCCGATGCCACAATTGCTCCAAGTTGTGATGCACCTGATACCAGCGTGCG
AGCGGTGGTCAGCTATTACGCCCCGACGCGGCTTGATTATTACAATGTGATCAAGCCTGAATTAGCGCCTGGCGCGTTGG
ATGATTACCTTGGTGGGCCGCCCGAAGCTCATGCTGAAGCCTATCGTCAAGCTCGCCCAGCCAATTGGGTCGGTCAAAAT
ACCCCAGCCACTTTGTTGTTGCACGGCGGGCGTGATCAATTTATTCGTCCAATTGACGCTGATCTGATGGCTGATGCCTT
GGAGCAAGCTAACCGCCCATTTACCATGATTGAATTACCCTTGGCCAATCATGGCTTTGATTTCAACTTAAATGGCGTGA
GTAACCAGCAAGTGCAGCCTTACGTGGCTCAATTTTTGGCCGAAGCGTTGCAATAA

Upstream 100 bases:

>100_bases
ATTTGTGACAGCATTTGGGCATGATCGTTGCTATAATTCTGGCTCAAAAGGCGGTACAATAACGCCGATCCGCTACAAGC
ATGGCTGCAAAGGAGCCTGT

Downstream 100 bases:

>100_bases
TCAGGAGCTAGCCTATGAATGAATCTGTCTATAAACTACTCGATTTTAGCCAGCCCGTAACTTTTGAACTGCTTTTGCAA
CATGCTTGGCAGTTGATTGC

Product: esterase/lipase-like

Products: alcohol; a carboxylate [C]

Alternate protein names: Lipase; Alpha/Beta Hydrolase Fold-3 Domain Protein; Esterase/Lipase; Lipase/Esterase; Esterase; Esterase/Lipase-Like Protein; Alpha/Beta Hydrolase; Esterase/Lipase/Thioesterase Family Protein; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Esterase/Lipase/Thioesterase; Hydrolase; Alpha/Beta Hydrolase Fold Domain Protein; Alpha/Beta Hydrolase Fold Protein-3 Domain Protein; Carboxylesterase Family Protein; Esterase LipO; Pectinesterase; Esterase/Lipase-Like; Peptidase S9 Prolyl Oligopeptidase; Carboxylesterase Type B; Lipase/Esterase Protein; Carboxylesterase LipQ; Dienelactone Hydrolase; Carboxylesterase; Peptidase; Esterase LipC; Peptidase S; Secreted Lipase/Esterase; Lipoprotein; Membrane-Bound Esterase LipM; Alpha/Beta Hydrolase Fold Protein; Membrane-Anchored Peptidase; Esterase-Hydrolase; Alpha/Beta Hydrolase Fold Family Protein; Coagulation Factor 5/8 Type Domain Protein; Dipeptidyl Aminopeptidases/Acylaminoacyl-Peptidases-Like; Alpha/Beta Hydrolase Family Protein; Phospholipase/Carboxylesterase; Arylesterase; Lipase LipA; Peptidase S9A/B/C Families; Para-Nitrobenzyl Esterase; Esterase LipM; Hydrolase Alpha/Beta Domain Protein

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRLALTIIILPIVLLALASAAMLVLPAPNFIFFQLGIAAQEWAPWFLLVLLVSLGLLFGFAPPTGLARLLNRLVGFGAML
SFIVIAGMLVRGLMTDLRVRSNQPTVVAAGPGTFRLSQFALGDPAPQGLLREQNTVYAEVAGESLLVDVYVPPTAPVNAP
ALIVVHGGSWRGGTKGDIPAWNRWAAGQGYVVFDVSYRLAPQAQFPAAVSDVKCAIGYVRRNAEQFGIDPQRLGLVGRSA
GAQLVLIAAYSDATIAPSCDAPDTSVRAVVSYYAPTRLDYYNVIKPELAPGALDDYLGGPPEAHAEAYRQARPANWVGQN
TPATLLLHGGRDQFIRPIDADLMADALEQANRPFTMIELPLANHGFDFNLNGVSNQQVQPYVAQFLAEALQ

Sequences:

>Translated_391_residues
MRLALTIIILPIVLLALASAAMLVLPAPNFIFFQLGIAAQEWAPWFLLVLLVSLGLLFGFAPPTGLARLLNRLVGFGAML
SFIVIAGMLVRGLMTDLRVRSNQPTVVAAGPGTFRLSQFALGDPAPQGLLREQNTVYAEVAGESLLVDVYVPPTAPVNAP
ALIVVHGGSWRGGTKGDIPAWNRWAAGQGYVVFDVSYRLAPQAQFPAAVSDVKCAIGYVRRNAEQFGIDPQRLGLVGRSA
GAQLVLIAAYSDATIAPSCDAPDTSVRAVVSYYAPTRLDYYNVIKPELAPGALDDYLGGPPEAHAEAYRQARPANWVGQN
TPATLLLHGGRDQFIRPIDADLMADALEQANRPFTMIELPLANHGFDFNLNGVSNQQVQPYVAQFLAEALQ
>Mature_391_residues
MRLALTIIILPIVLLALASAAMLVLPAPNFIFFQLGIAAQEWAPWFLLVLLVSLGLLFGFAPPTGLARLLNRLVGFGAML
SFIVIAGMLVRGLMTDLRVRSNQPTVVAAGPGTFRLSQFALGDPAPQGLLREQNTVYAEVAGESLLVDVYVPPTAPVNAP
ALIVVHGGSWRGGTKGDIPAWNRWAAGQGYVVFDVSYRLAPQAQFPAAVSDVKCAIGYVRRNAEQFGIDPQRLGLVGRSA
GAQLVLIAAYSDATIAPSCDAPDTSVRAVVSYYAPTRLDYYNVIKPELAPGALDDYLGGPPEAHAEAYRQARPANWVGQN
TPATLLLHGGRDQFIRPIDADLMADALEQANRPFTMIELPLANHGFDFNLNGVSNQQVQPYVAQFLAEALQ

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 41955; Mature: 41955

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLALTIIILPIVLLALASAAMLVLPAPNFIFFQLGIAAQEWAPWFLLVLLVSLGLLFGF
CCCHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
APPTGLARLLNRLVGFGAMLSFIVIAGMLVRGLMTDLRVRSNQPTVVAAGPGTFRLSQFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEC
LGDPAPQGLLREQNTVYAEVAGESLLVDVYVPPTAPVNAPALIVVHGGSWRGGTKGDIPA
CCCCCCHHHHHCCCCEEEEECCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCC
WNRWAAGQGYVVFDVSYRLAPQAQFPAAVSDVKCAIGYVRRNAEQFGIDPQRLGLVGRSA
CCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHCCCHHHHCEEECCC
GAQLVLIAAYSDATIAPSCDAPDTSVRAVVSYYAPTRLDYYNVIKPELAPGALDDYLGGP
CCEEEEEEEECCCEECCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHCCCC
PEAHAEAYRQARPANWVGQNTPATLLLHGGRDQFIRPIDADLMADALEQANRPFTMIELP
CHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEE
LANHGFDFNLNGVSNQQVQPYVAQFLAEALQ
CCCCCCEEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRLALTIIILPIVLLALASAAMLVLPAPNFIFFQLGIAAQEWAPWFLLVLLVSLGLLFGF
CCCHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
APPTGLARLLNRLVGFGAMLSFIVIAGMLVRGLMTDLRVRSNQPTVVAAGPGTFRLSQFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEC
LGDPAPQGLLREQNTVYAEVAGESLLVDVYVPPTAPVNAPALIVVHGGSWRGGTKGDIPA
CCCCCCHHHHHCCCCEEEEECCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCC
WNRWAAGQGYVVFDVSYRLAPQAQFPAAVSDVKCAIGYVRRNAEQFGIDPQRLGLVGRSA
CCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHCCCHHHHCEEECCC
GAQLVLIAAYSDATIAPSCDAPDTSVRAVVSYYAPTRLDYYNVIKPELAPGALDDYLGGP
CCEEEEEEEECCCEECCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHCCCC
PEAHAEAYRQARPANWVGQNTPATLLLHGGRDQFIRPIDADLMADALEQANRPFTMIELP
CHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEE
LANHGFDFNLNGVSNQQVQPYVAQFLAEALQ
CCCCCCEEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA