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The map label for this gene is aofH [H]

Identifier: 159897875

GI number: 159897875

Start: 1564032

End: 1565438

Strand: Direct

Name: aofH [H]

Synonym: Haur_1349

Alternate gene names: 159897875

Gene position: 1564032-1565438 (Clockwise)

Preceding gene: 159897869

Following gene: 159897880

Centisome position: 24.64

GC content: 51.88

Gene sequence:

>1407_bases
ATGCCCTACACACGGCGCGATATCCTGAAACTTGCGGCACTCGTTAGCCTTAGTCCATGGCTGCCTGCTTGTACACCCAA
TGATCCGAATACACCAACCATCAAGCCAACCACTACATCGAATAGCCCAGTAACGAGTGACAGCACCCCACAGGTCATCG
TAATTGGAGCGGGAATTGCTGGATTAGCCGCTGCCGCCAAACTCCAAGCAAACGGCTATCGCGTCCAGATCATCGAAGGG
CGCGATCGGATCGGCGGGCGCATTTGGACAAGCCGCACCTGGAACGATATGCCTGTCGATTTAGGGGCTTCGTGGATTCA
TGGAGTCACACAGAATCCCCTCACCGATCTGGCAGATACTGCTAGGATTGAGCGAACACCCACCGATTATGAAAATAGTC
TGGTCTATACCATGGAGGGTGATGAACTCGACGATGCCGCTGTGGAACAGCTTGAGGAGCAGTTGGTCACACTGCTGGAT
GCTGTGGCTGAGTTGGTTGAAGATACCGATGATATGTCACTCGCAGCGGCGATGCAGCAGGTTCTCGTTGAACAAGCTGA
ATCAATCGATCAACCACGCTTGAATTTCAGCATCAATAGCACGATTGAACATGAGTATGCTGCCGATGTCGAGGAATTAT
CAGCCCAGTATTGGGACAACGATGGGGAAGTTGTTGGGGGTGATGTGATCTTTCTTGATGGGTATGATCAAATCCTTGAT
CAACTCACGGCGGGCCTCACGATCCACACTGGGCAACCCGTTAACGCAATCAATTACACTGCTGAATCAATCACGATCAC
AACCGATACCACTACGTTTGAAGCGGAGCACGTCATTATCACCGTTCCGCTCGGTGTGCTCAAACAGGGCCGTATTCAGT
TCACTCCACCGCTCGATACCATAAAAACCGATGCGATCACCTTGCTCAGATCAGGGCTGCTCAACAAGACATGGCTGCGC
TTTGCAAGCGCGTTCTGGCCCAAGGAACCGGAGATCATTAACTATATTGATGAACAAAAAGGCCGTTGGGCCGAATTCCT
CAACATCTATCACTATACCGATAAACCGATCTTGCTCGGCTTTAATGCTGGTTCGTATGCTCGTATGCTTGAATCACGCA
GCGATGCGGAGATTATTGCCGATGGGATGCAAGTCCTGCGAACGATCTATGGGCAGGAAATTCCTGATCCTGAGGCGTGG
CAAATCACCCGCTGGGGCGCTGACCCCTATGCATTTGGTTCATACTCCTTTTTGGTCGTTGGCGCAACCGATGCCCTGCG
TGATGACCTTGCACAACCGATTGCTGGACGATTGTTCTTCGCGGGAGAAGCAACAGAACGCACCTATCCCTTCCATGGAG
CCTACCTCAGTGGATTGCGTGCCGCCGATGAGGTGATGCAGGCATAG

Upstream 100 bases:

>100_bases
ATAAAACTATCTCTTGCCTCATTGAATCCATATCTTTCTAACCGAATCCTAGCCAGAATGGTTGTGCGAAGTCATATAAT
CACCTTTATTTGGAGGATGT

Downstream 100 bases:

>100_bases
ATTGAACTCCAATGATTAACGTTCACAGCCTAAAACCACAAACGACCCGCTGGGGTCGCTTGTGGGAGAGAAGAGAGAGG
AGAAGGTTTGACTTCAGTAT

Product: amine oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MPYTRRDILKLAALVSLSPWLPACTPNDPNTPTIKPTTTSNSPVTSDSTPQVIVIGAGIAGLAAAAKLQANGYRVQIIEG
RDRIGGRIWTSRTWNDMPVDLGASWIHGVTQNPLTDLADTARIERTPTDYENSLVYTMEGDELDDAAVEQLEEQLVTLLD
AVAELVEDTDDMSLAAAMQQVLVEQAESIDQPRLNFSINSTIEHEYAADVEELSAQYWDNDGEVVGGDVIFLDGYDQILD
QLTAGLTIHTGQPVNAINYTAESITITTDTTTFEAEHVIITVPLGVLKQGRIQFTPPLDTIKTDAITLLRSGLLNKTWLR
FASAFWPKEPEIINYIDEQKGRWAEFLNIYHYTDKPILLGFNAGSYARMLESRSDAEIIADGMQVLRTIYGQEIPDPEAW
QITRWGADPYAFGSYSFLVVGATDALRDDLAQPIAGRLFFAGEATERTYPFHGAYLSGLRAADEVMQA

Sequences:

>Translated_468_residues
MPYTRRDILKLAALVSLSPWLPACTPNDPNTPTIKPTTTSNSPVTSDSTPQVIVIGAGIAGLAAAAKLQANGYRVQIIEG
RDRIGGRIWTSRTWNDMPVDLGASWIHGVTQNPLTDLADTARIERTPTDYENSLVYTMEGDELDDAAVEQLEEQLVTLLD
AVAELVEDTDDMSLAAAMQQVLVEQAESIDQPRLNFSINSTIEHEYAADVEELSAQYWDNDGEVVGGDVIFLDGYDQILD
QLTAGLTIHTGQPVNAINYTAESITITTDTTTFEAEHVIITVPLGVLKQGRIQFTPPLDTIKTDAITLLRSGLLNKTWLR
FASAFWPKEPEIINYIDEQKGRWAEFLNIYHYTDKPILLGFNAGSYARMLESRSDAEIIADGMQVLRTIYGQEIPDPEAW
QITRWGADPYAFGSYSFLVVGATDALRDDLAQPIAGRLFFAGEATERTYPFHGAYLSGLRAADEVMQA
>Mature_467_residues
PYTRRDILKLAALVSLSPWLPACTPNDPNTPTIKPTTTSNSPVTSDSTPQVIVIGAGIAGLAAAAKLQANGYRVQIIEGR
DRIGGRIWTSRTWNDMPVDLGASWIHGVTQNPLTDLADTARIERTPTDYENSLVYTMEGDELDDAAVEQLEEQLVTLLDA
VAELVEDTDDMSLAAAMQQVLVEQAESIDQPRLNFSINSTIEHEYAADVEELSAQYWDNDGEVVGGDVIFLDGYDQILDQ
LTAGLTIHTGQPVNAINYTAESITITTDTTTFEAEHVIITVPLGVLKQGRIQFTPPLDTIKTDAITLLRSGLLNKTWLRF
ASAFWPKEPEIINYIDEQKGRWAEFLNIYHYTDKPILLGFNAGSYARMLESRSDAEIIADGMQVLRTIYGQEIPDPEAWQ
ITRWGADPYAFGSYSFLVVGATDALRDDLAQPIAGRLFFAGEATERTYPFHGAYLSGLRAADEVMQA

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family [H]

Homologues:

Organism=Homo sapiens, GI116256451, Length=355, Percent_Identity=31.5492957746479, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI58761546, Length=292, Percent_Identity=34.5890410958904, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI58761544, Length=292, Percent_Identity=34.5890410958904, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI23097272, Length=487, Percent_Identity=28.952772073922, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI28559074, Length=523, Percent_Identity=25.4302103250478, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI28559076, Length=480, Percent_Identity=26.25, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI28559080, Length=510, Percent_Identity=25.4901960784314, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI46397310, Length=408, Percent_Identity=25.9803921568627, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210286, Length=470, Percent_Identity=26.1702127659574, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17558184, Length=481, Percent_Identity=27.027027027027, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17509955, Length=259, Percent_Identity=30.5019305019305, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI32566280, Length=204, Percent_Identity=30.8823529411765, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323662, Length=520, Percent_Identity=25.5769230769231, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21355313, Length=551, Percent_Identity=25.7713248638838, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24667273, Length=379, Percent_Identity=30.0791556728232, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI21356479, Length=379, Percent_Identity=30.0791556728232, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24661247, Length=472, Percent_Identity=28.1779661016949, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24666069, Length=475, Percent_Identity=28.2105263157895, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19922014, Length=497, Percent_Identity=27.1629778672032, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24666065, Length=473, Percent_Identity=29.1754756871036, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001613
- InterPro:   IPR002937 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 51597; Mature: 51466

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYTRRDILKLAALVSLSPWLPACTPNDPNTPTIKPTTTSNSPVTSDSTPQVIVIGAGIA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCHH
GLAAAAKLQANGYRVQIIEGRDRIGGRIWTSRTWNDMPVDLGASWIHGVTQNPLTDLADT
HHHHHHEEECCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHH
ARIERTPTDYENSLVYTMEGDELDDAAVEQLEEQLVTLLDAVAELVEDTDDMSLAAAMQQ
HHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VLVEQAESIDQPRLNFSINSTIEHEYAADVEELSAQYWDNDGEVVGGDVIFLDGYDQILD
HHHHHHHHCCCCCEEEEECCCCCHHHHCCHHHHHHHHCCCCCCEECCCEEEECCHHHHHH
QLTAGLTIHTGQPVNAINYTAESITITTDTTTFEAEHVIITVPLGVLKQGRIQFTPPLDT
HHHCCEEEECCCCCCCEEEEEEEEEEEECCEEEECCEEEEEECHHHHCCCCEEECCCHHH
IKTDAITLLRSGLLNKTWLRFASAFWPKEPEIINYIDEQKGRWAEFLNIYHYTDKPILLG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHEEECCCCEEEE
FNAGSYARMLESRSDAEIIADGMQVLRTIYGQEIPDPEAWQITRWGADPYAFGSYSFLVV
ECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEE
GATDALRDDLAQPIAGRLFFAGEATERTYPFHGAYLSGLRAADEVMQA
ECCHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PYTRRDILKLAALVSLSPWLPACTPNDPNTPTIKPTTTSNSPVTSDSTPQVIVIGAGIA
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCHH
GLAAAAKLQANGYRVQIIEGRDRIGGRIWTSRTWNDMPVDLGASWIHGVTQNPLTDLADT
HHHHHHEEECCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHH
ARIERTPTDYENSLVYTMEGDELDDAAVEQLEEQLVTLLDAVAELVEDTDDMSLAAAMQQ
HHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VLVEQAESIDQPRLNFSINSTIEHEYAADVEELSAQYWDNDGEVVGGDVIFLDGYDQILD
HHHHHHHHCCCCCEEEEECCCCCHHHHCCHHHHHHHHCCCCCCEECCCEEEECCHHHHHH
QLTAGLTIHTGQPVNAINYTAESITITTDTTTFEAEHVIITVPLGVLKQGRIQFTPPLDT
HHHCCEEEECCCCCCCEEEEEEEEEEEECCEEEECCEEEEEECHHHHCCCCEEECCCHHH
IKTDAITLLRSGLLNKTWLRFASAFWPKEPEIINYIDEQKGRWAEFLNIYHYTDKPILLG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHEEECCCCEEEE
FNAGSYARMLESRSDAEIIADGMQVLRTIYGQEIPDPEAWQITRWGADPYAFGSYSFLVV
ECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEE
GATDALRDDLAQPIAGRLFFAGEATERTYPFHGAYLSGLRAADEVMQA
ECCHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]