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The map label for this gene is nadA

Identifier: 159897818

GI number: 159897818

Start: 1499254

End: 1500381

Strand: Reverse

Name: nadA

Synonym: Haur_1289

Alternate gene names: 159897818

Gene position: 1500381-1499254 (Counterclockwise)

Preceding gene: 159897820

Following gene: 159897816

Centisome position: 23.64

GC content: 50.98

Gene sequence:

>1128_bases
ATGACCGTCATCGCAGCCGAAGCAATTGGCGTGGCACATGAACGTGCCGAGGACTATGCAGGGCTTTCAATCGAGGAATT
GGATCAACGGATTGCTACGGCTAAGGCCAAATTGGGCGAACGTTTGGTGATTCTGGGCCATCACTATCAACGTGATGATG
TGGTCAAGCATGCCGATTTAAGTGGCGATTCCTATGGGCTTTCGGTTGATGCACGCAAAACTGCCGCCGAATATATCGTC
TTTTGTGGCGTTCACTTTATGGCCGAAAGCGCCGATATTCTCGGGCGCGACGACCAAACTGTGATTCTGCCCGACCATAC
CGCTGGTTGCTCGATGGCTGATATGGCCGATATCGAACAGCTTGAAGAAGTTTGGGATGAGCTTGATGAGATTTTGGGTG
ATGCCGAGGCTCAGGTAATGCCAATTACTTACGTCAACTCATCGGCAGCCGTCAAGGCTTTTGTCGGCGAACATGGCGGG
GCTTGCTGCACCTCATCCAACGCTGAGCCAATTGTGCGCTGGGCCAAAAATCTCCGCCCCAAAATGCTGTTTCTGCCTGA
TCAGCACCTTGGCCGCTATACCGCGTTTGCCAAGCTCGGCATTCCGCTCGATAAAATGTTGGTCTGGAATCCCAATTTAC
GCTATGGTGGGCATACGCCAGAGGCCATTCGCGAGGCTGAAGTGTTGCTGTGGGCTGGTCACTGCTCGGTACACGCCCAA
TTCCGCCCAGCCTACATCAAAGCTTGGCGCGAAAAACACCCCGAAATTAATGTGATTGTACACCCTGAATGCACCTTGGG
CGTAACCAACGAGGCTGATTATGTTGGCTCAACGGCCTACATCATCAAAACGATCAACGAGGCTCCAGCAGGCAGTATGT
GGGCGGTTGGCACCGAAATCAACTTGGTCAATCGTTTACAAACCAACAATCCTGATAAAACGATTGTCTCTGTCTCGCCG
TTTGCCTGTCTTTGTTCAACCATGTATCGGATCGATCCTGAGGAATTATGTTGGGTTTTGGAGAATTTGGTCGAGGGCAA
TGTCGTCAATCAAATCGCTGTGCCAACTGCCATCAAGCAAAAAGCCCGTTTGGCACTCGAACGAATGTTAGAGATTGCTG
GTAATTAA

Upstream 100 bases:

>100_bases
AATGACATTATTAGGGGCGTTTGATACGTCCCGCTCTTTTTCTCACGATTTATAGTGTCAAAATGACACTTACTAAATGT
TTACCCAATGGAGAGTCATC

Downstream 100 bases:

>100_bases
GCGTTTCCCTCACCCCCTAGCCCCCTCTCCCGCACGCGAGGCGAGGGGGAACCCATTCAGCATGAACGTTGGAATGCCCC
TCGCCCGCCGCAGTGGGCGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTVIAAEAIGVAHERAEDYAGLSIEELDQRIATAKAKLGERLVILGHHYQRDDVVKHADLSGDSYGLSVDARKTAAEYIV
FCGVHFMAESADILGRDDQTVILPDHTAGCSMADMADIEQLEEVWDELDEILGDAEAQVMPITYVNSSAAVKAFVGEHGG
ACCTSSNAEPIVRWAKNLRPKMLFLPDQHLGRYTAFAKLGIPLDKMLVWNPNLRYGGHTPEAIREAEVLLWAGHCSVHAQ
FRPAYIKAWREKHPEINVIVHPECTLGVTNEADYVGSTAYIIKTINEAPAGSMWAVGTEINLVNRLQTNNPDKTIVSVSP
FACLCSTMYRIDPEELCWVLENLVEGNVVNQIAVPTAIKQKARLALERMLEIAGN

Sequences:

>Translated_375_residues
MTVIAAEAIGVAHERAEDYAGLSIEELDQRIATAKAKLGERLVILGHHYQRDDVVKHADLSGDSYGLSVDARKTAAEYIV
FCGVHFMAESADILGRDDQTVILPDHTAGCSMADMADIEQLEEVWDELDEILGDAEAQVMPITYVNSSAAVKAFVGEHGG
ACCTSSNAEPIVRWAKNLRPKMLFLPDQHLGRYTAFAKLGIPLDKMLVWNPNLRYGGHTPEAIREAEVLLWAGHCSVHAQ
FRPAYIKAWREKHPEINVIVHPECTLGVTNEADYVGSTAYIIKTINEAPAGSMWAVGTEINLVNRLQTNNPDKTIVSVSP
FACLCSTMYRIDPEELCWVLENLVEGNVVNQIAVPTAIKQKARLALERMLEIAGN
>Mature_374_residues
TVIAAEAIGVAHERAEDYAGLSIEELDQRIATAKAKLGERLVILGHHYQRDDVVKHADLSGDSYGLSVDARKTAAEYIVF
CGVHFMAESADILGRDDQTVILPDHTAGCSMADMADIEQLEEVWDELDEILGDAEAQVMPITYVNSSAAVKAFVGEHGGA
CCTSSNAEPIVRWAKNLRPKMLFLPDQHLGRYTAFAKLGIPLDKMLVWNPNLRYGGHTPEAIREAEVLLWAGHCSVHAQF
RPAYIKAWREKHPEINVIVHPECTLGVTNEADYVGSTAYIIKTINEAPAGSMWAVGTEINLVNRLQTNNPDKTIVSVSPF
ACLCSTMYRIDPEELCWVLENLVEGNVVNQIAVPTAIKQKARLALERMLEIAGN

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=365, Percent_Identity=26.5753424657534, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_HERA2 (A9B1Q2)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001544065.1
- ProteinModelPortal:   A9B1Q2
- SMR:   A9B1Q2
- GeneID:   5733182
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_1289
- HOGENOM:   HBG291157
- OMA:   GTELNLV
- ProtClustDB:   PRK09375
- BioCyc:   HAUR316274:HAUR_1289-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00569
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 41245; Mature: 41114

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: BINDING 47-47 BINDING 64-64 BINDING 144-144 BINDING 165-165 BINDING 261-261 BINDING 278-278

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVIAAEAIGVAHERAEDYAGLSIEELDQRIATAKAKLGERLVILGHHYQRDDVVKHADL
CEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCC
SGDSYGLSVDARKTAAEYIVFCGVHFMAESADILGRDDQTVILPDHTAGCSMADMADIEQ
CCCCCEEEECHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCCCCHHHHHHHHH
LEEVWDELDEILGDAEAQVMPITYVNSSAAVKAFVGEHGGACCTSSNAEPIVRWAKNLRP
HHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHCCCCCCEECCCCCHHHHHHHHCCCC
KMLFLPDQHLGRYTAFAKLGIPLDKMLVWNPNLRYGGHTPEAIREAEVLLWAGHCSVHAQ
EEEECCCHHCCHHHHHHHCCCCHHHEEEECCCCCCCCCCHHHHHCCEEEEEECCEEEEEE
FRPAYIKAWREKHPEINVIVHPECTLGVTNEADYVGSTAYIIKTINEAPAGSMWAVGTEI
CCHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEECCCH
NLVNRLQTNNPDKTIVSVSPFACLCSTMYRIDPEELCWVLENLVEGNVVNQIAVPTAIKQ
HHHHHHCCCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHH
KARLALERMLEIAGN
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVIAAEAIGVAHERAEDYAGLSIEELDQRIATAKAKLGERLVILGHHYQRDDVVKHADL
EEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCC
SGDSYGLSVDARKTAAEYIVFCGVHFMAESADILGRDDQTVILPDHTAGCSMADMADIEQ
CCCCCEEEECHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCCCCCHHHHHHHHH
LEEVWDELDEILGDAEAQVMPITYVNSSAAVKAFVGEHGGACCTSSNAEPIVRWAKNLRP
HHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHCCCCCCEECCCCCHHHHHHHHCCCC
KMLFLPDQHLGRYTAFAKLGIPLDKMLVWNPNLRYGGHTPEAIREAEVLLWAGHCSVHAQ
EEEECCCHHCCHHHHHHHCCCCHHHEEEECCCCCCCCCCHHHHHCCEEEEEECCEEEEEE
FRPAYIKAWREKHPEINVIVHPECTLGVTNEADYVGSTAYIIKTINEAPAGSMWAVGTEI
CCHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEECCCH
NLVNRLQTNNPDKTIVSVSPFACLCSTMYRIDPEELCWVLENLVEGNVVNQIAVPTAIKQ
HHHHHHCCCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHH
KARLALERMLEIAGN
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA