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The map label for this gene is ddc [H]

Identifier: 159897770

GI number: 159897770

Start: 1446021

End: 1447421

Strand: Reverse

Name: ddc [H]

Synonym: Haur_1241

Alternate gene names: 159897770

Gene position: 1447421-1446021 (Counterclockwise)

Preceding gene: 159897780

Following gene: 159897769

Centisome position: 22.81

GC content: 53.6

Gene sequence:

>1401_bases
ATGCATCCAGTTTTAGCCCACGATGCCGCTCAAATCGACCACATTTTAGCGCAGACCCTTGCCACAGCCAAACAATTTCT
CCACGATTTGCCACAGCGTCCGGTTGGAGTTGCGCCGCAAAGCCACCAACCAAGCCAATTACCAAGCGCTGGATTAGGAG
CCGAACAAACGCTTGAGCATTTTTTGGCCCGCTACAGCGATACATTAACTGGTAGCACTGGTCCGCGCTATTGGGGCTTC
GTCACTGGCGGCGCAACTCCGGCAGCACTGGCAGGCGATTGGCTGGTCAGCACCTTCGATCAGAATCCAAGTGGCACAAC
CGAAACCGCCGCGATTCGGGTTGAAAACGAAGCCATCAGCATGTTGCGCGAACTCTTTGGCTTGCCCACAAGCTTTAGCG
GCGCATTCGTTTCTGGGGCAACGATGGCCAATTTTGTCGGCTTGGCGATTGGGCGGCAATGGGCGGCTCAACAACTCAAC
CATGATGTTGCCCGCATGGGTTTATATGGGCTTGCGCCAATTCCAGTTTTGAGCGGAGCACCGCACTCAAGCATTTACAA
GGCCATGTCAATGTTGGGCATGGGTCGTCAACAGCTGCAAACAATCGCCTTACAGCCCGAACGCGAGGCGGTTGACATCG
CAGCATTACGTCAAGCACTTCAAGCCTTGTCAGCGAACCAACCTGCGATCGTTGTTGCCAATGCAGGCACGGTCAATAGT
GTCGATTTTGACGATCTTATGGCAATTGCCGCGCTCAAGCAGGAATTCAATTTCTGGTTGCATGTTGATGCGGCTTTTGG
TGGTTTTGCCGCCTGTTCGCCGCGCTTTGCTCATTTAGTGCATGGGCTTGAACAAGCCGATTCGCTGACGATTGATGCCC
ACAAATGGCTCAATGTGCCGTATGATTCAGCTATGCAATTCACCCGCCATAGTGCCTTGCAAGTTGAGGTGTTTCATAAT
AGCGCGGCCTACCTCAGCCCAATTGGCGAGAATCCAGGCTTTTTTCATCGCACGCCCGAAAATTCACGCCGTTGGCGAGC
ACTGCCAGCATGGTTCACGCTTATGGCCTATGGCTCGGCTGGCTATCAAGAAATGGTTGAGCGCGATTGCGATTTAGCCC
AACTGCTGGCTAGCCATATCAGCGATTCACCGTTGTTTCGCTTGGTCGCGCCTGTGCGCATGAACGTCGTTTGTTTCACT
TTGGCGGGCAATCCTGATAGCACTACAATTCAGGCTTATCTTGATGCAGTACGGGCTAGCGGAGCAGTTTTTATGACCGC
GACTGTCTATGCTGGACAACCAGCGATTCGCGCGGCCTTCTCAAATTGGCGCACCACCACCGCCGATGTTGGGCTGGCTT
GGCAGGCAATGGAGCGAGTCGCCATAGAACATAGAGCATAG

Upstream 100 bases:

>100_bases
GGATCATAATTGGTCGGGTTAAATGCTCAAAAGTGGTGCTTAACCAAGCCACTTGAGTTTGCTATGCTCAAGCTAGTTCT
GAATTAATTGAGGTAGCCCA

Downstream 100 bases:

>100_bases
AGCATAGAACATAGAGCATAGAAGTTGGGGATCGGTTGGCGGGGGTTGGGGATCAGGCTGTTGGCCATTGATCACAGGAA
TATAATCCTCCAAATCTGTG

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MHPVLAHDAAQIDHILAQTLATAKQFLHDLPQRPVGVAPQSHQPSQLPSAGLGAEQTLEHFLARYSDTLTGSTGPRYWGF
VTGGATPAALAGDWLVSTFDQNPSGTTETAAIRVENEAISMLRELFGLPTSFSGAFVSGATMANFVGLAIGRQWAAQQLN
HDVARMGLYGLAPIPVLSGAPHSSIYKAMSMLGMGRQQLQTIALQPEREAVDIAALRQALQALSANQPAIVVANAGTVNS
VDFDDLMAIAALKQEFNFWLHVDAAFGGFAACSPRFAHLVHGLEQADSLTIDAHKWLNVPYDSAMQFTRHSALQVEVFHN
SAAYLSPIGENPGFFHRTPENSRRWRALPAWFTLMAYGSAGYQEMVERDCDLAQLLASHISDSPLFRLVAPVRMNVVCFT
LAGNPDSTTIQAYLDAVRASGAVFMTATVYAGQPAIRAAFSNWRTTTADVGLAWQAMERVAIEHRA

Sequences:

>Translated_466_residues
MHPVLAHDAAQIDHILAQTLATAKQFLHDLPQRPVGVAPQSHQPSQLPSAGLGAEQTLEHFLARYSDTLTGSTGPRYWGF
VTGGATPAALAGDWLVSTFDQNPSGTTETAAIRVENEAISMLRELFGLPTSFSGAFVSGATMANFVGLAIGRQWAAQQLN
HDVARMGLYGLAPIPVLSGAPHSSIYKAMSMLGMGRQQLQTIALQPEREAVDIAALRQALQALSANQPAIVVANAGTVNS
VDFDDLMAIAALKQEFNFWLHVDAAFGGFAACSPRFAHLVHGLEQADSLTIDAHKWLNVPYDSAMQFTRHSALQVEVFHN
SAAYLSPIGENPGFFHRTPENSRRWRALPAWFTLMAYGSAGYQEMVERDCDLAQLLASHISDSPLFRLVAPVRMNVVCFT
LAGNPDSTTIQAYLDAVRASGAVFMTATVYAGQPAIRAAFSNWRTTTADVGLAWQAMERVAIEHRA
>Mature_466_residues
MHPVLAHDAAQIDHILAQTLATAKQFLHDLPQRPVGVAPQSHQPSQLPSAGLGAEQTLEHFLARYSDTLTGSTGPRYWGF
VTGGATPAALAGDWLVSTFDQNPSGTTETAAIRVENEAISMLRELFGLPTSFSGAFVSGATMANFVGLAIGRQWAAQQLN
HDVARMGLYGLAPIPVLSGAPHSSIYKAMSMLGMGRQQLQTIALQPEREAVDIAALRQALQALSANQPAIVVANAGTVNS
VDFDDLMAIAALKQEFNFWLHVDAAFGGFAACSPRFAHLVHGLEQADSLTIDAHKWLNVPYDSAMQFTRHSALQVEVFHN
SAAYLSPIGENPGFFHRTPENSRRWRALPAWFTLMAYGSAGYQEMVERDCDLAQLLASHISDSPLFRLVAPVRMNVVCFT
LAGNPDSTTIQAYLDAVRASGAVFMTATVYAGQPAIRAAFSNWRTTTADVGLAWQAMERVAIEHRA

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI4503281, Length=258, Percent_Identity=27.906976744186, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI132814448, Length=258, Percent_Identity=27.906976744186, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI58331246, Length=462, Percent_Identity=27.4891774891775, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI197276620, Length=438, Percent_Identity=26.4840182648402, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4503875, Length=438, Percent_Identity=26.4840182648402, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI194294551, Length=446, Percent_Identity=26.6816143497758, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI92110055, Length=369, Percent_Identity=23.8482384823848, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI197383062, Length=339, Percent_Identity=26.5486725663717, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534817, Length=464, Percent_Identity=25.6465517241379, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17534819, Length=433, Percent_Identity=26.3279445727483, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71993062, Length=342, Percent_Identity=25.4385964912281, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17555682, Length=342, Percent_Identity=25.4385964912281, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71993058, Length=333, Percent_Identity=25.8258258258258, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71981211, Length=277, Percent_Identity=23.1046931407942, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI133931025, Length=431, Percent_Identity=22.2737819025522, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17551992, Length=284, Percent_Identity=23.2394366197183, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71981217, Length=277, Percent_Identity=23.1046931407942, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24585135, Length=237, Percent_Identity=31.2236286919831, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136594, Length=360, Percent_Identity=27.5, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24652373, Length=373, Percent_Identity=28.9544235924933, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136190, Length=237, Percent_Identity=31.2236286919831, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24585139, Length=290, Percent_Identity=28.9655172413793, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI221476190, Length=290, Percent_Identity=28.9655172413793, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24585143, Length=290, Percent_Identity=28.9655172413793, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573972, Length=450, Percent_Identity=26.6666666666667, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24586044, Length=414, Percent_Identity=25.3623188405797, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21356415, Length=338, Percent_Identity=27.2189349112426, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24657193, Length=416, Percent_Identity=24.5192307692308, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24657185, Length=416, Percent_Identity=24.5192307692308, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24657188, Length=416, Percent_Identity=24.5192307692308, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 50324; Mature: 50324

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPVLAHDAAQIDHILAQTLATAKQFLHDLPQRPVGVAPQSHQPSQLPSAGLGAEQTLEH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
FLARYSDTLTGSTGPRYWGFVTGGATPAALAGDWLVSTFDQNPSGTTETAAIRVENEAIS
HHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCHHHEECCCCCCCCCCEEEEEECHHHHH
MLRELFGLPTSFSGAFVSGATMANFVGLAIGRQWAAQQLNHDVARMGLYGLAPIPVLSGA
HHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PHSSIYKAMSMLGMGRQQLQTIALQPEREAVDIAALRQALQALSANQPAIVVANAGTVNS
CHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
VDFDDLMAIAALKQEFNFWLHVDAAFGGFAACSPRFAHLVHGLEQADSLTIDAHKWLNVP
CCHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHCCEEEEHHHHCCCC
YDSAMQFTRHSALQVEVFHNSAAYLSPIGENPGFFHRTPENSRRWRALPAWFTLMAYGSA
HHHHHHHHHCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCC
GYQEMVERDCDLAQLLASHISDSPLFRLVAPVRMNVVCFTLAGNPDSTTIQAYLDAVRAS
CHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCC
GAVFMTATVYAGQPAIRAAFSNWRTTTADVGLAWQAMERVAIEHRA
CEEEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHPVLAHDAAQIDHILAQTLATAKQFLHDLPQRPVGVAPQSHQPSQLPSAGLGAEQTLEH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
FLARYSDTLTGSTGPRYWGFVTGGATPAALAGDWLVSTFDQNPSGTTETAAIRVENEAIS
HHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCHHHEECCCCCCCCCCEEEEEECHHHHH
MLRELFGLPTSFSGAFVSGATMANFVGLAIGRQWAAQQLNHDVARMGLYGLAPIPVLSGA
HHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PHSSIYKAMSMLGMGRQQLQTIALQPEREAVDIAALRQALQALSANQPAIVVANAGTVNS
CHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
VDFDDLMAIAALKQEFNFWLHVDAAFGGFAACSPRFAHLVHGLEQADSLTIDAHKWLNVP
CCHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHCCEEEEHHHHCCCC
YDSAMQFTRHSALQVEVFHNSAAYLSPIGENPGFFHRTPENSRRWRALPAWFTLMAYGSA
HHHHHHHHHCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHCCC
GYQEMVERDCDLAQLLASHISDSPLFRLVAPVRMNVVCFTLAGNPDSTTIQAYLDAVRAS
CHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHCC
GAVFMTATVYAGQPAIRAAFSNWRTTTADVGLAWQAMERVAIEHRA
CEEEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]