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The map label for this gene is thrC [H]

Identifier: 159897747

GI number: 159897747

Start: 1409294

End: 1410931

Strand: Direct

Name: thrC [H]

Synonym: Haur_1218

Alternate gene names: 159897747

Gene position: 1409294-1410931 (Clockwise)

Preceding gene: 159897746

Following gene: 159897748

Centisome position: 22.21

GC content: 50.37

Gene sequence:

>1638_bases
ATGACAGATTTAGTTTGCCAGAACTGTGGCCATATTCAGCCATACACCTTTCGTAGCTCGAATAGCTGTGCCCAATGTGC
TAATGATTGGCTTGAGACGCATTACGATTATGCCAACTTTTGCGAGTTGGTGCGTAATCAGCAACTGAGCGGCCAGACGT
TATGGCGCTATAGTAGCGTTTTGCCGGTGCCGCCACCAGCTGCGCCAACCCATGTTGGTGGAACGCCCTTGTTGCATGCC
CAGCGCTTTGGTGGTTTGTTGGGCTTGCCACGCTTGTATATTAAAGATGAGCGCTATAGCCCAACCAATTCGTTTAAAGA
TCGCCAAGCAGCTTTGGCCGTAGCCGCCTTAGTTTCGAATGATATTCGCGAATGCGTGATTGCCTCGACTGGCAATGCGG
CGGTGGCCTATGCCTCGGCTTGTGCCGCAGTTGGCATCAAACTGTGGGTCTTTATGACCAGCGTGGTGCCAGAAGCAAAA
TTACGCGAAGCGGCCTTGTTTGGGGCTGAGGTGATCAAAGTTAGTGGCAATTATGATCAAACTAAGCAGATTGCCGCTGA
TTTTGCCCAAAACCGCAATATCATCTACGATCGTGGCGCTAACAGCATTCCGGCGCGGGAAGCCATGAAAACGATCAGCT
ACGAAATTTGCGAGCAACTTGGCTGGCAAGCGCCCGATTGGTATATTCAGGCAGTTAGTGGTGGCTTGGGGCCATTAGGG
GTTTATCACGGGTTTGCCGAATTGCATGCCATGGGCTTGACCCAGCGCGTACCTCAAACCGCGATTATTCAAGCTGAAGG
CTGCTCACCGATGGTGCAGGCATTTCAGGCTGGCAAATCGGTGGCTGAAAAAGTTGTACCAAATACGCGGATTGCGATTC
TTTCAACAGGCGATCCTGGTAAGATCTATACGCGGCTTTGGCAACGCATCCAAACATCGGGCGGTACGATGGAAGCCGTC
ACCGATGAAGAGGCCTTCAGTGCAATGCGCTTATTGGCGCGAACTGAAGGTATTTCGGTGGAGCCAGCTACGGCTGTGGC
ATTTGCGGGCCTGCAAAAAATGGTGGCCCAAGGCCAAGTTAACCCTGAAGAATTAATTGTGGTAAATTGTACTGGGCACA
CCTTCCCAGTCGATAAGCATGTGCTGAACGATCAATGGCATATTGATGTACATGTCAGCGATACCCAACAATCAGCGCCC
CAAGAAGGGCTTCAGGTGGCGCTGGAACAATTGAATGAAAAAGCGACAACGGTGTTGTTGATCGACGATAATCCTGATGA
TGCTCAATTGGTGCAGCGTATTTTAGAGCGACGCAAAGCCTACCGCGTTTATCGGGCAACCGATGGTGCCGATGGTGTGC
AACAAGCAATTCAACGGCTGCCTGATGCTATTGTGATGGATTTAATGATGCCAAATATGGATGGGTTTCAGGTGATGAGT
ACCTTACGCCAACACCCCAAAACCCGTGATATTCCGATTATTGTGGTGAGCGCCAAGGATATTACGCCTGATGAGCGCCA
TCATTTAGCCACCCATACCCGTGCTGTGTATCAAAAAGGCTCACTTTCACCAGTTGCCTTTGTCGAACAGGTTGTGAGTG
TCATTGAACACAAAGAGCGTGATAGTGAGGACCAATGA

Upstream 100 bases:

>100_bases
GATGAAGTTAATCCTAATGCAGCGCCAGCCAATCAACCTATGTCTGTAGAATAATGGTTATGCGCATTGTGCTGCGGCAT
AAGCGCGTGGTAAGGGCGTT

Downstream 100 bases:

>100_bases
GTACAACCGTTGTCTTATATATCGAAGATAACCCTGATAATATGCTGTTGGTGGAGCGCCTGTTGATTGCCCGTGGTTGT
CAAATGCTCAAGGCAATCAA

Product: response regulator receiver protein

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MTDLVCQNCGHIQPYTFRSSNSCAQCANDWLETHYDYANFCELVRNQQLSGQTLWRYSSVLPVPPPAAPTHVGGTPLLHA
QRFGGLLGLPRLYIKDERYSPTNSFKDRQAALAVAALVSNDIRECVIASTGNAAVAYASACAAVGIKLWVFMTSVVPEAK
LREAALFGAEVIKVSGNYDQTKQIAADFAQNRNIIYDRGANSIPAREAMKTISYEICEQLGWQAPDWYIQAVSGGLGPLG
VYHGFAELHAMGLTQRVPQTAIIQAEGCSPMVQAFQAGKSVAEKVVPNTRIAILSTGDPGKIYTRLWQRIQTSGGTMEAV
TDEEAFSAMRLLARTEGISVEPATAVAFAGLQKMVAQGQVNPEELIVVNCTGHTFPVDKHVLNDQWHIDVHVSDTQQSAP
QEGLQVALEQLNEKATTVLLIDDNPDDAQLVQRILERRKAYRVYRATDGADGVQQAIQRLPDAIVMDLMMPNMDGFQVMS
TLRQHPKTRDIPIIVVSAKDITPDERHHLATHTRAVYQKGSLSPVAFVEQVVSVIEHKERDSEDQ

Sequences:

>Translated_545_residues
MTDLVCQNCGHIQPYTFRSSNSCAQCANDWLETHYDYANFCELVRNQQLSGQTLWRYSSVLPVPPPAAPTHVGGTPLLHA
QRFGGLLGLPRLYIKDERYSPTNSFKDRQAALAVAALVSNDIRECVIASTGNAAVAYASACAAVGIKLWVFMTSVVPEAK
LREAALFGAEVIKVSGNYDQTKQIAADFAQNRNIIYDRGANSIPAREAMKTISYEICEQLGWQAPDWYIQAVSGGLGPLG
VYHGFAELHAMGLTQRVPQTAIIQAEGCSPMVQAFQAGKSVAEKVVPNTRIAILSTGDPGKIYTRLWQRIQTSGGTMEAV
TDEEAFSAMRLLARTEGISVEPATAVAFAGLQKMVAQGQVNPEELIVVNCTGHTFPVDKHVLNDQWHIDVHVSDTQQSAP
QEGLQVALEQLNEKATTVLLIDDNPDDAQLVQRILERRKAYRVYRATDGADGVQQAIQRLPDAIVMDLMMPNMDGFQVMS
TLRQHPKTRDIPIIVVSAKDITPDERHHLATHTRAVYQKGSLSPVAFVEQVVSVIEHKERDSEDQ
>Mature_544_residues
TDLVCQNCGHIQPYTFRSSNSCAQCANDWLETHYDYANFCELVRNQQLSGQTLWRYSSVLPVPPPAAPTHVGGTPLLHAQ
RFGGLLGLPRLYIKDERYSPTNSFKDRQAALAVAALVSNDIRECVIASTGNAAVAYASACAAVGIKLWVFMTSVVPEAKL
REAALFGAEVIKVSGNYDQTKQIAADFAQNRNIIYDRGANSIPAREAMKTISYEICEQLGWQAPDWYIQAVSGGLGPLGV
YHGFAELHAMGLTQRVPQTAIIQAEGCSPMVQAFQAGKSVAEKVVPNTRIAILSTGDPGKIYTRLWQRIQTSGGTMEAVT
DEEAFSAMRLLARTEGISVEPATAVAFAGLQKMVAQGQVNPEELIVVNCTGHTFPVDKHVLNDQWHIDVHVSDTQQSAPQ
EGLQVALEQLNEKATTVLLIDDNPDDAQLVQRILERRKAYRVYRATDGADGVQQAIQRLPDAIVMDLMMPNMDGFQVMST
LRQHPKTRDIPIIVVSAKDITPDERHHLATHTRAVYQKGSLSPVAFVEQVVSVIEHKERDSEDQ

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 59863; Mature: 59731

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLVCQNCGHIQPYTFRSSNSCAQCANDWLETHYDYANFCELVRNQQLSGQTLWRYSSV
CCCCHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHCCC
LPVPPPAAPTHVGGTPLLHAQRFGGLLGLPRLYIKDERYSPTNSFKDRQAALAVAALVSN
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHH
DIRECVIASTGNAAVAYASACAAVGIKLWVFMTSVVPEAKLREAALFGAEVIKVSGNYDQ
HHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCH
TKQIAADFAQNRNIIYDRGANSIPAREAMKTISYEICEQLGWQAPDWYIQAVSGGLGPLG
HHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHH
VYHGFAELHAMGLTQRVPQTAIIQAEGCSPMVQAFQAGKSVAEKVVPNTRIAILSTGDPG
HHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
KIYTRLWQRIQTSGGTMEAVTDEEAFSAMRLLARTEGISVEPATAVAFAGLQKMVAQGQV
HHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
NPEELIVVNCTGHTFPVDKHVLNDQWHIDVHVSDTQQSAPQEGLQVALEQLNEKATTVLL
CHHHEEEEEECCCCCCCCHHHCCCCEEEEEEECCCHHCCHHHHHHHHHHHHCCCCEEEEE
IDDNPDDAQLVQRILERRKAYRVYRATDGADGVQQAIQRLPDAIVMDLMMPNMDGFQVMS
EECCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHH
TLRQHPKTRDIPIIVVSAKDITPDERHHLATHTRAVYQKGSLSPVAFVEQVVSVIEHKER
HHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
DSEDQ
CCCCC
>Mature Secondary Structure 
TDLVCQNCGHIQPYTFRSSNSCAQCANDWLETHYDYANFCELVRNQQLSGQTLWRYSSV
CCCHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHCCC
LPVPPPAAPTHVGGTPLLHAQRFGGLLGLPRLYIKDERYSPTNSFKDRQAALAVAALVSN
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHH
DIRECVIASTGNAAVAYASACAAVGIKLWVFMTSVVPEAKLREAALFGAEVIKVSGNYDQ
HHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCH
TKQIAADFAQNRNIIYDRGANSIPAREAMKTISYEICEQLGWQAPDWYIQAVSGGLGPLG
HHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHH
VYHGFAELHAMGLTQRVPQTAIIQAEGCSPMVQAFQAGKSVAEKVVPNTRIAILSTGDPG
HHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
KIYTRLWQRIQTSGGTMEAVTDEEAFSAMRLLARTEGISVEPATAVAFAGLQKMVAQGQV
HHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
NPEELIVVNCTGHTFPVDKHVLNDQWHIDVHVSDTQQSAPQEGLQVALEQLNEKATTVLL
CHHHEEEEEECCCCCCCCHHHCCCCEEEEEEECCCHHCCHHHHHHHHHHHHCCCCEEEEE
IDDNPDDAQLVQRILERRKAYRVYRATDGADGVQQAIQRLPDAIVMDLMMPNMDGFQVMS
EECCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHH
TLRQHPKTRDIPIIVVSAKDITPDERHHLATHTRAVYQKGSLSPVAFVEQVVSVIEHKER
HHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
DSEDQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]