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The map label for this gene is degS [H]

Identifier: 159897511

GI number: 159897511

Start: 1124779

End: 1125819

Strand: Direct

Name: degS [H]

Synonym: Haur_0982

Alternate gene names: 159897511

Gene position: 1124779-1125819 (Clockwise)

Preceding gene: 159897510

Following gene: 159897512

Centisome position: 17.72

GC content: 55.04

Gene sequence:

>1041_bases
ATGCGACGGATACCACTGATTTACCAGATTTTAATCGGCAATAGTGCAATAGTTTGTTTGGGCGCAATCGCTGGCACGGC
GATCACACGCCGCTTAGCAACGACCGAAGGCTTGACCTTAACGGTTGTTTTTTCGTTGATCGGGGTTGTGCTGAGTGTTG
CAGTCAATTATGCAGTTTTGCGCGTAGCACTACGCCCGCTCACCAATCTGCAAATTGCCGCCGAGCGCGTGACCGACGGC
GATTTGAGCGTGCGTGTGCCCCAGCCCAGTGCTGGCGATACCCAAATTGCCCAACTTTCGCAAGCTTTCAATGCAATGCT
TGACCAAGTTGAGGATGACACTCGCGCCATCGAGCGTTCACGCGCCTTGACCGAGCGCCTAACCCAGCAAGTGATCAACG
CGCAAGAAGAAGAACGGCGGCGGATCGCCCGTGAATTGCACGACGATACGGCGCAAGCCTTGGCAACCTTGGTGATCTAT
GCTGAAACTGCCGCGCAAAATCCCCAAGCCCAAGCGGTGCGCGAACGGCTGATTGGCTTGCGCGATTTGGCTGGTACGAC
CCTCGAAGGCGTGCGCACGATCATCGCCGATTTACGTCCATCGCAGCTTGATGACCTTGGTTTGGCCGCCGCCGTGCGTG
CTCAAGCCGCCGAACGTTTAGCCCATCGCGGAATTCGGGTTGATGTGCAAGTTCGTGGCGAGGAGCGCCGCCTCCCATCA
GCCGTCGAAACCGCGCTCTATCGCATGCTGCAAGAAGCATTTAGCAATATTGTGAAACATGCCCAAGCCTCGTATGTCGA
GGTCGATATCGACCTAACTAATCCCAAAATTGTACGAGCGCGGGTTGAAGATAATGGCGTTGGCTTTGACCCCAATACAA
TTAACCCTGAACGTGATGGCCGTGGAGTTGGCATGTTTGGGATGTATGAGCGGGTCAATCTTCTCGGTGGAACGATGGCG
ATCGATAGTGCACCTAGCATTGGCACTGAATTAACGATCACAGTTCCCTTGGAGCCAGCAACCCAAGCCAGCGCCGCCTA
A

Upstream 100 bases:

>100_bases
TGTGTGGCGGGGCTTGGGGTCGTTCTACTGGTTCTAATCGGCTAAAAACTATGGCTCAATCTTGGTTCATAAGATTGATG
GTTGATGATACAATACTGCT

Downstream 100 bases:

>100_bases
AGGATTGTGCTATGGCAATTGCCGAAATAACAATTTTATTGGCCGATGACCACGCTGTGATGCGTGATGGTGTGCGCATG
GTTTTGGAAGCTCAGCCCGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRRIPLIYQILIGNSAIVCLGAIAGTAITRRLATTEGLTLTVVFSLIGVVLSVAVNYAVLRVALRPLTNLQIAAERVTDG
DLSVRVPQPSAGDTQIAQLSQAFNAMLDQVEDDTRAIERSRALTERLTQQVINAQEEERRRIARELHDDTAQALATLVIY
AETAAQNPQAQAVRERLIGLRDLAGTTLEGVRTIIADLRPSQLDDLGLAAAVRAQAAERLAHRGIRVDVQVRGEERRLPS
AVETALYRMLQEAFSNIVKHAQASYVEVDIDLTNPKIVRARVEDNGVGFDPNTINPERDGRGVGMFGMYERVNLLGGTMA
IDSAPSIGTELTITVPLEPATQASAA

Sequences:

>Translated_346_residues
MRRIPLIYQILIGNSAIVCLGAIAGTAITRRLATTEGLTLTVVFSLIGVVLSVAVNYAVLRVALRPLTNLQIAAERVTDG
DLSVRVPQPSAGDTQIAQLSQAFNAMLDQVEDDTRAIERSRALTERLTQQVINAQEEERRRIARELHDDTAQALATLVIY
AETAAQNPQAQAVRERLIGLRDLAGTTLEGVRTIIADLRPSQLDDLGLAAAVRAQAAERLAHRGIRVDVQVRGEERRLPS
AVETALYRMLQEAFSNIVKHAQASYVEVDIDLTNPKIVRARVEDNGVGFDPNTINPERDGRGVGMFGMYERVNLLGGTMA
IDSAPSIGTELTITVPLEPATQASAA
>Mature_346_residues
MRRIPLIYQILIGNSAIVCLGAIAGTAITRRLATTEGLTLTVVFSLIGVVLSVAVNYAVLRVALRPLTNLQIAAERVTDG
DLSVRVPQPSAGDTQIAQLSQAFNAMLDQVEDDTRAIERSRALTERLTQQVINAQEEERRRIARELHDDTAQALATLVIY
AETAAQNPQAQAVRERLIGLRDLAGTTLEGVRTIIADLRPSQLDDLGLAAAVRAQAAERLAHRGIRVDVQVRGEERRLPS
AVETALYRMLQEAFSNIVKHAQASYVEVDIDLTNPKIVRARVEDNGVGFDPNTINPERDGRGVGMFGMYERVNLLGGTMA
IDSAPSIGTELTITVPLEPATQASAA

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=243, Percent_Identity=30.0411522633745, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787474, Length=201, Percent_Identity=32.3383084577114, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37485; Mature: 37485

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIPLIYQILIGNSAIVCLGAIAGTAITRRLATTEGLTLTVVFSLIGVVLSVAVNYAVL
CCCCCEEEHEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RVALRPLTNLQIAAERVTDGDLSVRVPQPSAGDTQIAQLSQAFNAMLDQVEDDTRAIERS
HHHHHHHCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALTERLTQQVINAQEEERRRIARELHDDTAQALATLVIYAETAAQNPQAQAVRERLIGL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RDLAGTTLEGVRTIIADLRPSQLDDLGLAAAVRAQAAERLAHRGIRVDVQVRGEERRLPS
HHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCCH
AVETALYRMLQEAFSNIVKHAQASYVEVDIDLTNPKIVRARVEDNGVGFDPNTINPERDG
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCC
RGVGMFGMYERVNLLGGTMAIDSAPSIGTELTITVPLEPATQASAA
CCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRRIPLIYQILIGNSAIVCLGAIAGTAITRRLATTEGLTLTVVFSLIGVVLSVAVNYAVL
CCCCCEEEHEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RVALRPLTNLQIAAERVTDGDLSVRVPQPSAGDTQIAQLSQAFNAMLDQVEDDTRAIERS
HHHHHHHCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALTERLTQQVINAQEEERRRIARELHDDTAQALATLVIYAETAAQNPQAQAVRERLIGL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RDLAGTTLEGVRTIIADLRPSQLDDLGLAAAVRAQAAERLAHRGIRVDVQVRGEERRLPS
HHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCCH
AVETALYRMLQEAFSNIVKHAQASYVEVDIDLTNPKIVRARVEDNGVGFDPNTINPERDG
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCC
RGVGMFGMYERVNLLGGTMAIDSAPSIGTELTITVPLEPATQASAA
CCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]