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The map label for this gene is yciC [H]

Identifier: 159897168

GI number: 159897168

Start: 736679

End: 737887

Strand: Reverse

Name: yciC [H]

Synonym: Haur_0639

Alternate gene names: 159897168

Gene position: 737887-736679 (Counterclockwise)

Preceding gene: 159897169

Following gene: 159897165

Centisome position: 11.63

GC content: 48.72

Gene sequence:

>1209_bases
ATGTCGAAGTTGCCGCTTCCCGTAACTGTACTTTCTGGTTTTCTTGGTGCAGGGAAAACCACCTTATTAAATCATATTTT
GGCCAACCGCGAGGGCTTGCGGGTCGCCGTCATCGTCAATGATATGAGCGAAGTTAATATCGATGCGCGGTTGGTTGGTC
AAGGCGAACTTGCACTCAATCGGGTCGAAGAACAATTGATCGAGCTCAGCAATGGTTGTATTTGCTGTACCTTGCGTGAA
GATTTGTTGCTTGAGGTTAGTAAGCTAGCTCGTGCTGGCCGATTCGATTATCTGCTGATCGAATCGACTGGTATTTCGGA
GCCGTTGCCCGTCGCCGAAACCTTTACTTTCGAGGATGAATCGGGCCTCAGTTTGGGCGAAATTGCCAAGCTCGATACGA
TGGTAACCGTGGTTGATGCACTCAATTTCTTACACGATTTCAATGCTGCTCACGATTTACGCGATCGTGATTTGGCGATC
GACGAGGCCGATGAGCGGACTTTGGTCGATTTATTGATCGATCAGATTGAGTTTTGCAATGTGTTAATCATTAATAAAAC
TGATTTGGTTAGTGCCGAACAATTAATCCATTTGCATGAATTGCTAAATAAACTCAATCCGCAAGCCAAGATTTTTCATG
CACAACATGGTCAAGTGCCACTCAACGAAATTCTGAATACAGGCTTGTTTGATTTTGATCAAGCAAGCGCTGCACCTGGT
TGGTTGGCCGAATTGCGCGGCGAACATACGCCCGAAACCGAGGAATATGGCATTCGCAGCTGGGTATATCGCGCTCGACG
GCCATTTGTCGCTCAGCGTTTTTGGGATTTTGTCAATAATGATTGGCCTGGCGTAATTCGCGCCAAAGGCTTCTTTTGGG
TAATTTCGCAGCCCGAGACGGCTGGCTTGCTTTCGCAGGCGGGCCAAAATTGCCGGGTCGAGCCAGCTGGACAATGGTGG
GCTGATAGCGATCAGAGCGAATGGCCGGAAACTGCCGAGGAACGCACCGAAATTGAAGCCTTGTGGGATGAGCAGGTCGG
CGACCGTCGGCAGGAACTCGTCTTTATCGGCCAAGATTTTGATCAACAATGGTTACAGCAAACGTTAGATGCCTGTTTGG
TTAGCGATCACGAATGGCAGCAACCTGCCGCAACGTGGCAAATCGATGATCCGTTTGCTGATTGGAATGAGTACGAAGCG
ATAGCTTAG

Upstream 100 bases:

>100_bases
GTATACTCCGCTTTGGCCGTTTTGTCAAACGCTGCTTGACGAATGCAAAAATCGATTATAATGATATATAGTATCAATAA
ATAGCAAGGATTAAAGCCAA

Downstream 100 bases:

>100_bases
CAAGTATAGGAAGAACCATGCCCCTGACCACCACCCCTCGCCCACTACGGTGGACGAGGGGTGGTGGTCAGGGGCATTCC
AAGGGTTGTTGATAATAGCC

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSKLPLPVTVLSGFLGAGKTTLLNHILANREGLRVAVIVNDMSEVNIDARLVGQGELALNRVEEQLIELSNGCICCTLRE
DLLLEVSKLARAGRFDYLLIESTGISEPLPVAETFTFEDESGLSLGEIAKLDTMVTVVDALNFLHDFNAAHDLRDRDLAI
DEADERTLVDLLIDQIEFCNVLIINKTDLVSAEQLIHLHELLNKLNPQAKIFHAQHGQVPLNEILNTGLFDFDQASAAPG
WLAELRGEHTPETEEYGIRSWVYRARRPFVAQRFWDFVNNDWPGVIRAKGFFWVISQPETAGLLSQAGQNCRVEPAGQWW
ADSDQSEWPETAEERTEIEALWDEQVGDRRQELVFIGQDFDQQWLQQTLDACLVSDHEWQQPAATWQIDDPFADWNEYEA
IA

Sequences:

>Translated_402_residues
MSKLPLPVTVLSGFLGAGKTTLLNHILANREGLRVAVIVNDMSEVNIDARLVGQGELALNRVEEQLIELSNGCICCTLRE
DLLLEVSKLARAGRFDYLLIESTGISEPLPVAETFTFEDESGLSLGEIAKLDTMVTVVDALNFLHDFNAAHDLRDRDLAI
DEADERTLVDLLIDQIEFCNVLIINKTDLVSAEQLIHLHELLNKLNPQAKIFHAQHGQVPLNEILNTGLFDFDQASAAPG
WLAELRGEHTPETEEYGIRSWVYRARRPFVAQRFWDFVNNDWPGVIRAKGFFWVISQPETAGLLSQAGQNCRVEPAGQWW
ADSDQSEWPETAEERTEIEALWDEQVGDRRQELVFIGQDFDQQWLQQTLDACLVSDHEWQQPAATWQIDDPFADWNEYEA
IA
>Mature_401_residues
SKLPLPVTVLSGFLGAGKTTLLNHILANREGLRVAVIVNDMSEVNIDARLVGQGELALNRVEEQLIELSNGCICCTLRED
LLLEVSKLARAGRFDYLLIESTGISEPLPVAETFTFEDESGLSLGEIAKLDTMVTVVDALNFLHDFNAAHDLRDRDLAID
EADERTLVDLLIDQIEFCNVLIINKTDLVSAEQLIHLHELLNKLNPQAKIFHAQHGQVPLNEILNTGLFDFDQASAAPGW
LAELRGEHTPETEEYGIRSWVYRARRPFVAQRFWDFVNNDWPGVIRAKGFFWVISQPETAGLLSQAGQNCRVEPAGQWWA
DSDQSEWPETAEERTEIEALWDEQVGDRRQELVFIGQDFDQQWLQQTLDACLVSDHEWQQPAATWQIDDPFADWNEYEAI
A

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=393, Percent_Identity=27.9898218829517, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI126722884, Length=394, Percent_Identity=27.9187817258883, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI146231952, Length=394, Percent_Identity=27.4111675126904, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI148727351, Length=394, Percent_Identity=27.9187817258883, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI223941779, Length=218, Percent_Identity=33.9449541284404, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI223941776, Length=384, Percent_Identity=27.34375, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI119120938, Length=138, Percent_Identity=39.1304347826087, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI87082430, Length=305, Percent_Identity=28.8524590163934, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788499, Length=213, Percent_Identity=25.8215962441315, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=242, Percent_Identity=29.7520661157025, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 45463; Mature: 45332

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLPLPVTVLSGFLGAGKTTLLNHILANREGLRVAVIVNDMSEVNIDARLVGQGELALN
CCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHCCCCEEEECCCHHHHH
RVEEQLIELSNGCICCTLREDLLLEVSKLARAGRFDYLLIESTGISEPLPVAETFTFEDE
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCC
SGLSLGEIAKLDTMVTVVDALNFLHDFNAAHDLRDRDLAIDEADERTLVDLLIDQIEFCN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
VLIINKTDLVSAEQLIHLHELLNKLNPQAKIFHAQHGQVPLNEILNTGLFDFDQASAAPG
EEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
WLAELRGEHTPETEEYGIRSWVYRARRPFVAQRFWDFVNNDWPGVIRAKGFFWVISQPET
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECEEEEEEECCCH
AGLLSQAGQNCRVEPAGQWWADSDQSEWPETAEERTEIEALWDEQVGDRRQELVFIGQDF
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
DQQWLQQTLDACLVSDHEWQQPAATWQIDDPFADWNEYEAIA
CHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SKLPLPVTVLSGFLGAGKTTLLNHILANREGLRVAVIVNDMSEVNIDARLVGQGELALN
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCHHHCCCCEEEECCCHHHHH
RVEEQLIELSNGCICCTLREDLLLEVSKLARAGRFDYLLIESTGISEPLPVAETFTFEDE
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCC
SGLSLGEIAKLDTMVTVVDALNFLHDFNAAHDLRDRDLAIDEADERTLVDLLIDQIEFCN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
VLIINKTDLVSAEQLIHLHELLNKLNPQAKIFHAQHGQVPLNEILNTGLFDFDQASAAPG
EEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
WLAELRGEHTPETEEYGIRSWVYRARRPFVAQRFWDFVNNDWPGVIRAKGFFWVISQPET
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECEEEEEEECCCH
AGLLSQAGQNCRVEPAGQWWADSDQSEWPETAEERTEIEALWDEQVGDRRQELVFIGQDF
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
DQQWLQQTLDACLVSDHEWQQPAATWQIDDPFADWNEYEAIA
CHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]