Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 159896941

GI number: 159896941

Start: 479199

End: 480437

Strand: Reverse

Name: csd [H]

Synonym: Haur_0409

Alternate gene names: 159896941

Gene position: 480437-479199 (Counterclockwise)

Preceding gene: 159896942

Following gene: 159896940

Centisome position: 7.57

GC content: 52.87

Gene sequence:

>1239_bases
ATGTCTGTACAAACAACCCTTGATATTCAGGCCATTCGCGAGCAATTCCCGCTCTTGGATCAATCGATTAACGGCCATCG
CCTAGCCTATTTGGATAGCACCGCAACTGCCCAAAAGCCGCTAGCAGTGCTTGATGCGATGGATCGCTATTATCGCACGA
TTAATGCGAATGTTCATCGAGGTGTGTATCAGATTAGCGAAGCCGCCACCGAAGCCTATGAAGGCACGCGCCGCACGATT
GGCCGCTTTATCGGCGCAAAATCGACCAAAGAAATTATTTTTACTCGCAACGCGACCGAAGCGATTAACTTGGTTGCCCA
AAGCTGGGGCCGTGCTAATTTGCAAGCGGGCGATCGAATTTTGCTCACAGTCAGCGAGCATCATTCAAATTTAGTGCCAT
GGCAATTGCTAGCAGCCCAAACTGGTGTAGAGCTTGATTTTATCGAGCTTGATGATCAAGGCCGACTTGATCTCAGCCAC
CTTGATCAACTATTGACTGAACGCACCAAATTGGTCGCCATGACCCACATGTCGAATGTGTTGGGCACGATCAATCCAGT
TGAACGGGTGATTGCGGCGGCCAAACAGGTTGGAGCCTTGGTGCTGCTGGATGGGGCGCAAAGTGTGCCACATATTCCCG
TCAATGTTCAAGCACTTGGCTGCGATTTCTTGGCCTTTTCGGGGCATAAAATGTGCGGTCCAACTGGGATTGGGGTGCTG
TGGGCGCGGCGCGAATTGCTTGAAGCCATGCCGCCGTTTATGGGTGGCGGCGATATGATCAAACGGGTCGGGCTACGCGA
AAGCTCATGGAACGATCTCCCATGGAAATTCGAGGCAGGCACGCCAGCGATTGCCGAGGCGATTGGCCTTGGCGCGGCGA
TTGACTTCTTGAATGAACTTGGGATGCAGGCGATTCACGAGCGCGAACGCCAATTGACCCACTACGCTTGGGATAAACTC
AGCGCCATCGATGGGTTGACCATTTTTGGTCCACCTGCTGCCGAGCGCGGTGGCTTGTTGAGCTTTACCCTTGCAGGTGT
GCATGCCCACGATGTGGCAGCGATTCTCGATACCCAAGGGATTGCAGTGCGGGCTGGGCATCATTGCACCCATCCATTGC
ACGATATTTTTGGCGTGCCAGCAACGGTACGCGCATCATTCTACCTATACACGCTTGAGGAAGAAATTGATCGTTTGGCC
GAAGCCTTGGTTTTGGCTCGCGATACCTTCCAACTGTGA

Upstream 100 bases:

>100_bases
TATAAAGCTTGGTAGAAATACCAAATCCAAACATTCGTGTCCTTCGTGGATCAAATAAACAATTCATGGTTTCCTTTATG
GAATCGGATATTGGTGAGTT

Downstream 100 bases:

>100_bases
GGCCTTGTGGACGATTTATATCGTGAAAATATATTAGATCATTATCGCCATCCGCGAAATTACGGCGAGATCGAACAAGC
AACGATTGTGCAACACGAGC

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSVQTTLDIQAIREQFPLLDQSINGHRLAYLDSTATAQKPLAVLDAMDRYYRTINANVHRGVYQISEAATEAYEGTRRTI
GRFIGAKSTKEIIFTRNATEAINLVAQSWGRANLQAGDRILLTVSEHHSNLVPWQLLAAQTGVELDFIELDDQGRLDLSH
LDQLLTERTKLVAMTHMSNVLGTINPVERVIAAAKQVGALVLLDGAQSVPHIPVNVQALGCDFLAFSGHKMCGPTGIGVL
WARRELLEAMPPFMGGGDMIKRVGLRESSWNDLPWKFEAGTPAIAEAIGLGAAIDFLNELGMQAIHERERQLTHYAWDKL
SAIDGLTIFGPPAAERGGLLSFTLAGVHAHDVAAILDTQGIAVRAGHHCTHPLHDIFGVPATVRASFYLYTLEEEIDRLA
EALVLARDTFQL

Sequences:

>Translated_412_residues
MSVQTTLDIQAIREQFPLLDQSINGHRLAYLDSTATAQKPLAVLDAMDRYYRTINANVHRGVYQISEAATEAYEGTRRTI
GRFIGAKSTKEIIFTRNATEAINLVAQSWGRANLQAGDRILLTVSEHHSNLVPWQLLAAQTGVELDFIELDDQGRLDLSH
LDQLLTERTKLVAMTHMSNVLGTINPVERVIAAAKQVGALVLLDGAQSVPHIPVNVQALGCDFLAFSGHKMCGPTGIGVL
WARRELLEAMPPFMGGGDMIKRVGLRESSWNDLPWKFEAGTPAIAEAIGLGAAIDFLNELGMQAIHERERQLTHYAWDKL
SAIDGLTIFGPPAAERGGLLSFTLAGVHAHDVAAILDTQGIAVRAGHHCTHPLHDIFGVPATVRASFYLYTLEEEIDRLA
EALVLARDTFQL
>Mature_411_residues
SVQTTLDIQAIREQFPLLDQSINGHRLAYLDSTATAQKPLAVLDAMDRYYRTINANVHRGVYQISEAATEAYEGTRRTIG
RFIGAKSTKEIIFTRNATEAINLVAQSWGRANLQAGDRILLTVSEHHSNLVPWQLLAAQTGVELDFIELDDQGRLDLSHL
DQLLTERTKLVAMTHMSNVLGTINPVERVIAAAKQVGALVLLDGAQSVPHIPVNVQALGCDFLAFSGHKMCGPTGIGVLW
ARRELLEAMPPFMGGGDMIKRVGLRESSWNDLPWKFEAGTPAIAEAIGLGAAIDFLNELGMQAIHERERQLTHYAWDKLS
AIDGLTIFGPPAAERGGLLSFTLAGVHAHDVAAILDTQGIAVRAGHHCTHPLHDIFGVPATVRASFYLYTLEEEIDRLAE
ALVLARDTFQL

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=392, Percent_Identity=25, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI156713448, Length=426, Percent_Identity=25.8215962441315, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787970, Length=398, Percent_Identity=50, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1789175, Length=392, Percent_Identity=41.8367346938776, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI48994898, Length=391, Percent_Identity=26.8542199488491, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25143064, Length=373, Percent_Identity=27.3458445040214, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193211090, Length=376, Percent_Identity=26.063829787234, Blast_Score=110, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6319831, Length=391, Percent_Identity=27.3657289002558, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI20129463, Length=415, Percent_Identity=26.0240963855422, Blast_Score=125, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45089; Mature: 44958

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQTTLDIQAIREQFPLLDQSINGHRLAYLDSTATAQKPLAVLDAMDRYYRTINANVHR
CCCCCHHHHHHHHHHCCCHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHH
GVYQISEAATEAYEGTRRTIGRFIGAKSTKEIIFTRNATEAINLVAQSWGRANLQAGDRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCEE
LLTVSEHHSNLVPWQLLAAQTGVELDFIELDDQGRLDLSHLDQLLTERTKLVAMTHMSNV
EEEEECCCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGTINPVERVIAAAKQVGALVLLDGAQSVPHIPVNVQALGCDFLAFSGHKMCGPTGIGVL
HHCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCHHHH
WARRELLEAMPPFMGGGDMIKRVGLRESSWNDLPWKFEAGTPAIAEAIGLGAAIDFLNEL
HHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
GMQAIHERERQLTHYAWDKLSAIDGLTIFGPPAAERGGLLSFTLAGVHAHDVAAILDTQG
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHCCCC
IAVRAGHHCTHPLHDIFGVPATVRASFYLYTLEEEIDRLAEALVLARDTFQL
EEEECCCCCCCCHHHHHCCCHHHHHEEEEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVQTTLDIQAIREQFPLLDQSINGHRLAYLDSTATAQKPLAVLDAMDRYYRTINANVHR
CCCCHHHHHHHHHHCCCHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHH
GVYQISEAATEAYEGTRRTIGRFIGAKSTKEIIFTRNATEAINLVAQSWGRANLQAGDRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCEE
LLTVSEHHSNLVPWQLLAAQTGVELDFIELDDQGRLDLSHLDQLLTERTKLVAMTHMSNV
EEEEECCCCCCCCHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGTINPVERVIAAAKQVGALVLLDGAQSVPHIPVNVQALGCDFLAFSGHKMCGPTGIGVL
HHCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCHHHH
WARRELLEAMPPFMGGGDMIKRVGLRESSWNDLPWKFEAGTPAIAEAIGLGAAIDFLNEL
HHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
GMQAIHERERQLTHYAWDKLSAIDGLTIFGPPAAERGGLLSFTLAGVHAHDVAAILDTQG
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHCCCC
IAVRAGHHCTHPLHDIFGVPATVRASFYLYTLEEEIDRLAEALVLARDTFQL
EEEECCCCCCCCHHHHHCCCHHHHHEEEEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]