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The map label for this gene is yycG [H]

Identifier: 159896838

GI number: 159896838

Start: 363943

End: 366207

Strand: Direct

Name: yycG [H]

Synonym: Haur_0305

Alternate gene names: 159896838

Gene position: 363943-366207 (Clockwise)

Preceding gene: 159896837

Following gene: 159896839

Centisome position: 5.73

GC content: 52.54

Gene sequence:

>2265_bases
ATGACTGAACGATCACGGCAACGCGGCCATCAACAGCTCCAAACTATGCGCAGCAAACGGATTCAGGCGCGACTGCTAGC
GCTCTCACGGGTCATGAACGATATTATGAATGTTGATGATCCAGCGCGATTGATCACTGCTGCCAGTGCCAAATTGCGCC
AGGTTTTAGCTGTTGATGCCATTGCAGTGTGGTTTTATAGTCCTACTTCACATCGTTACCTACTAAGCCACTTCAATAAT
GCCAACCACGAAGATTTTAGTGCAGATGATCGCGAGGCCTTAAGTGCTTTGCAAGTGCGCAGCGGCGAGGCGTTGGCTGG
GCGTGTGGTCAGTGAAGGCCATGCGATCAGCGCCCGCAACGCCGACGAATATCGCAGCATGTTTGGCGCATTGGGTCGCC
GCCGCGAGGCCTTATTCAATCGCTGGCGAGCGCTCCTGCCAATTTCATTTCAAGTAACCGGTTTCACGCTGGGCGGCAAT
GGGCGACCCAGCGGCGTGATTGAGCTTTTCAGTAGCAAGCCCAGCATCAATGCTAACTCGGCTGCTTGGCTACAACCAAC
CCTTGATCAGCTTGGTTCGTTGTTGCAGTTAGTGCGTCAACAGGCCGATGCCCGTAGCCAGCGCCGCCGTTTGGCCGCCC
TCGATGCCGTCGTTACCGCGATTAGCACCTCTTCCGACTTGCCCGACCTCTTAAATGTGGCGCTGTTGGTGGTGATTGAG
GTAGTCAGCGCCAATGGTGGGGCAATTTGTTTGGCCTCGCCTGGTGGCCGTAGCATGACTTTAGCCGCGCAACATCAACT
CCCGCAACGCGAGGCTTTGCTCCTTGGTTCGAGCCAAGCCAACAGCGTGTTGGAAGATGTCGTTTACTACGGCCAGCCAA
CCTTGCGACCCGTGATCAGCACCAGCGATCTTGGCGAGGATATTATGGGTCGCGCTGCCATGCCTTTGCTGGCTGGGGGC
ACAATCGTCGGGGTTTTGGTGTTATATGGCAATTACCAAACGCTCTCGAATAATATCGATTGGCCTTCGCTGGTTTCGAT
GGGTTCGCAAATTGGCATCGCGATTGCCAATACCCGTTTATACGAAGAAAGCCAACGCGAACGCCAACGGCTGGGCACGG
TGATCGAATCGATCGCTGATGGCGTGGCAATTTGTAATGGCGTTGGCGAATTAATTCTGGCCAACGAAACCGCAGCGGGC
TTGGTGGAAATTTCAATTCTGCCCACCTTAGCCACCAGCAGCGAATCGGGCGCACGCTACCTTGATGGCACGTTTGTCGA
AGCTGATATGCTGCCATTTGCCCGCGCTTTGGCTGGTGAAGTGTTCCGCGATTATCGTTTAATTGTGCCAGGCAGCCAAG
ACCAAGATGTGGTGCTGAGCTTCAGCGGTGCACCGTTGCGCCGTTCAGTATTAATTGATAGTACTGAAACATCGTTTGAT
GGTGCAGTAATCGTGTTTCGCGATATTACCGAGCAACGCCGTTTGGAAGAGGCCAAGGATGAGTTTTTAGCGGTTGCTGC
TCACGAACTGCGCTCACCACTGGCGGCAATCAAAGGCTACAGCGATTTGTTGCTGCGCCGCGAGTTGAAGCAAGCCAGCG
AAGGCCGTGATTTGCGCGGCTTTATCACCTTGAGCCAGCAAGTCAATATTATGGTGCAGTTGGTCGATAATTTGCTTGAT
GTTTCACGAATTGATGCCGAGCGCTATACGATTCAGCTTGATGCGGTTGATTTGGGGATCTTGCTTGATTCAGTTGTGAC
CCATGCTCGCCAAACCGCCAACAATCATACCTTACATTTTGAGCAACTCAACCAGAGCGTCGTCTATGGCGATTCGCTAA
AATTGCGCCAAGTTGCTACCAATTTTCTGACTAATGCAATTCGCTATAGCCCGCAACAAACCAACATTTGGGTGCAAGTG
TTTAGCGATGAACAATTTGGCTATGTCCAAGTTGATGATCAAGGGCCAGGCATTCCACAAGGCCAACGCGAACGTTTGTT
TGAACGCTACTACAGAGTGCCGGGGATTCGCCGTACCGGATCGAGCACCGAAGGTTTGGGTTTAGGCTTGTATTTATGTC
GCGAAATTATTACACTGCACAATGGGCGAATTTGGGTTGATAGCGCTCCGAGCGGCGGCGCACGCTTTTGCATCGCCATT
CCGCGCTTTATCCCTGAAAAACATGAAACCAACACAACCCAAACCACCCTCGATCTCGATGCCTTTTTATTCTCGCCCCA
ACCAGGCCGGAGGAATGATGAATAG

Upstream 100 bases:

>100_bases
GAGCACGCCAACTCTTGGGTTACACGCCCCAAGTTGCTTTAGCCGATGGTTTACGGCGAGCAGTCGCGTGGAACATTGCG
TGGGACGAGGAACAGCGGCG

Downstream 100 bases:

>100_bases
TAGTGTGATTGCAGTATTACGTCGCGTCGATATTTTTGCTGGGCTAAACGATCTCGAGTTAAGCCAAATTGCCCAATTGT
GCAAAGTTGCCAAGGCCAAA

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 753

Protein sequence:

>754_residues
MTERSRQRGHQQLQTMRSKRIQARLLALSRVMNDIMNVDDPARLITAASAKLRQVLAVDAIAVWFYSPTSHRYLLSHFNN
ANHEDFSADDREALSALQVRSGEALAGRVVSEGHAISARNADEYRSMFGALGRRREALFNRWRALLPISFQVTGFTLGGN
GRPSGVIELFSSKPSINANSAAWLQPTLDQLGSLLQLVRQQADARSQRRRLAALDAVVTAISTSSDLPDLLNVALLVVIE
VVSANGGAICLASPGGRSMTLAAQHQLPQREALLLGSSQANSVLEDVVYYGQPTLRPVISTSDLGEDIMGRAAMPLLAGG
TIVGVLVLYGNYQTLSNNIDWPSLVSMGSQIGIAIANTRLYEESQRERQRLGTVIESIADGVAICNGVGELILANETAAG
LVEISILPTLATSSESGARYLDGTFVEADMLPFARALAGEVFRDYRLIVPGSQDQDVVLSFSGAPLRRSVLIDSTETSFD
GAVIVFRDITEQRRLEEAKDEFLAVAAHELRSPLAAIKGYSDLLLRRELKQASEGRDLRGFITLSQQVNIMVQLVDNLLD
VSRIDAERYTIQLDAVDLGILLDSVVTHARQTANNHTLHFEQLNQSVVYGDSLKLRQVATNFLTNAIRYSPQQTNIWVQV
FSDEQFGYVQVDDQGPGIPQGQRERLFERYYRVPGIRRTGSSTEGLGLGLYLCREIITLHNGRIWVDSAPSGGARFCIAI
PRFIPEKHETNTTQTTLDLDAFLFSPQPGRRNDE

Sequences:

>Translated_754_residues
MTERSRQRGHQQLQTMRSKRIQARLLALSRVMNDIMNVDDPARLITAASAKLRQVLAVDAIAVWFYSPTSHRYLLSHFNN
ANHEDFSADDREALSALQVRSGEALAGRVVSEGHAISARNADEYRSMFGALGRRREALFNRWRALLPISFQVTGFTLGGN
GRPSGVIELFSSKPSINANSAAWLQPTLDQLGSLLQLVRQQADARSQRRRLAALDAVVTAISTSSDLPDLLNVALLVVIE
VVSANGGAICLASPGGRSMTLAAQHQLPQREALLLGSSQANSVLEDVVYYGQPTLRPVISTSDLGEDIMGRAAMPLLAGG
TIVGVLVLYGNYQTLSNNIDWPSLVSMGSQIGIAIANTRLYEESQRERQRLGTVIESIADGVAICNGVGELILANETAAG
LVEISILPTLATSSESGARYLDGTFVEADMLPFARALAGEVFRDYRLIVPGSQDQDVVLSFSGAPLRRSVLIDSTETSFD
GAVIVFRDITEQRRLEEAKDEFLAVAAHELRSPLAAIKGYSDLLLRRELKQASEGRDLRGFITLSQQVNIMVQLVDNLLD
VSRIDAERYTIQLDAVDLGILLDSVVTHARQTANNHTLHFEQLNQSVVYGDSLKLRQVATNFLTNAIRYSPQQTNIWVQV
FSDEQFGYVQVDDQGPGIPQGQRERLFERYYRVPGIRRTGSSTEGLGLGLYLCREIITLHNGRIWVDSAPSGGARFCIAI
PRFIPEKHETNTTQTTLDLDAFLFSPQPGRRNDE
>Mature_753_residues
TERSRQRGHQQLQTMRSKRIQARLLALSRVMNDIMNVDDPARLITAASAKLRQVLAVDAIAVWFYSPTSHRYLLSHFNNA
NHEDFSADDREALSALQVRSGEALAGRVVSEGHAISARNADEYRSMFGALGRRREALFNRWRALLPISFQVTGFTLGGNG
RPSGVIELFSSKPSINANSAAWLQPTLDQLGSLLQLVRQQADARSQRRRLAALDAVVTAISTSSDLPDLLNVALLVVIEV
VSANGGAICLASPGGRSMTLAAQHQLPQREALLLGSSQANSVLEDVVYYGQPTLRPVISTSDLGEDIMGRAAMPLLAGGT
IVGVLVLYGNYQTLSNNIDWPSLVSMGSQIGIAIANTRLYEESQRERQRLGTVIESIADGVAICNGVGELILANETAAGL
VEISILPTLATSSESGARYLDGTFVEADMLPFARALAGEVFRDYRLIVPGSQDQDVVLSFSGAPLRRSVLIDSTETSFDG
AVIVFRDITEQRRLEEAKDEFLAVAAHELRSPLAAIKGYSDLLLRRELKQASEGRDLRGFITLSQQVNIMVQLVDNLLDV
SRIDAERYTIQLDAVDLGILLDSVVTHARQTANNHTLHFEQLNQSVVYGDSLKLRQVATNFLTNAIRYSPQQTNIWVQVF
SDEQFGYVQVDDQGPGIPQGQRERLFERYYRVPGIRRTGSSTEGLGLGLYLCREIITLHNGRIWVDSAPSGGARFCIAIP
RFIPEKHETNTTQTTLDLDAFLFSPQPGRRNDE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=32.9218106995885, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=27.9693486590038, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=30.4721030042918, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=30.7377049180328, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1789149, Length=246, Percent_Identity=30.8943089430894, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=30.1204819277108, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1788279, Length=214, Percent_Identity=26.6355140186916, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788713, Length=272, Percent_Identity=26.8382352941176, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788549, Length=273, Percent_Identity=28.2051282051282, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.8702928870293, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=26.007326007326, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=32.258064516129, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=25.8771929824561, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789403, Length=216, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=25.5813953488372, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=257, Percent_Identity=26.0700389105058, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=247, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=27.7533039647577, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82841; Mature: 82710

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERSRQRGHQQLQTMRSKRIQARLLALSRVMNDIMNVDDPARLITAASAKLRQVLAVDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IAVWFYSPTSHRYLLSHFNNANHEDFSADDREALSALQVRSGEALAGRVVSEGHAISARN
EEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEECCC
ADEYRSMFGALGRRREALFNRWRALLPISFQVTGFTLGGNGRPSGVIELFSSKPSINANS
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCHHHEEECCCCCCCCCC
AAWLQPTLDQLGSLLQLVRQQADARSQRRRLAALDAVVTAISTSSDLPDLLNVALLVVIE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VVSANGGAICLASPGGRSMTLAAQHQLPQREALLLGSSQANSVLEDVVYYGQPTLRPVIS
HHCCCCCEEEEECCCCCEEEEEHHHCCCCCHHEEECCCHHHHHHHHHHHHCCCCCCCCCC
TSDLGEDIMGRAAMPLLAGGTIVGVLVLYGNYQTLSNNIDWPSLVSMGSQIGIAIANTRL
CCCCCHHHHHHHHCHHHCCCHHHHHHHHCCCCHHHCCCCCCHHHHHCCCCCEEEEECCHH
YEESQRERQRLGTVIESIADGVAICNGVGELILANETAAGLVEISILPTLATSSESGARY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEEECCCCCCCEE
LDGTFVEADMLPFARALAGEVFRDYRLIVPGSQDQDVVLSFSGAPLRRSVLIDSTETSFD
CCCCEEEHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCC
GAVIVFRDITEQRRLEEAKDEFLAVAAHELRSPLAAIKGYSDLLLRRELKQASEGRDLRG
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEE
FITLSQQVNIMVQLVDNLLDVSRIDAERYTIQLDAVDLGILLDSVVTHARQTANNHTLHF
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEH
EQLNQSVVYGDSLKLRQVATNFLTNAIRYSPQQTNIWVQVFSDEQFGYVQVDDQGPGIPQ
HHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCCCCCCCC
GQRERLFERYYRVPGIRRTGSSTEGLGLGLYLCREIITLHNGRIWVDSAPSGGARFCIAI
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
PRFIPEKHETNTTQTTLDLDAFLFSPQPGRRNDE
HHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TERSRQRGHQQLQTMRSKRIQARLLALSRVMNDIMNVDDPARLITAASAKLRQVLAVDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IAVWFYSPTSHRYLLSHFNNANHEDFSADDREALSALQVRSGEALAGRVVSEGHAISARN
EEEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEECCC
ADEYRSMFGALGRRREALFNRWRALLPISFQVTGFTLGGNGRPSGVIELFSSKPSINANS
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCHHHEEECCCCCCCCCC
AAWLQPTLDQLGSLLQLVRQQADARSQRRRLAALDAVVTAISTSSDLPDLLNVALLVVIE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VVSANGGAICLASPGGRSMTLAAQHQLPQREALLLGSSQANSVLEDVVYYGQPTLRPVIS
HHCCCCCEEEEECCCCCEEEEEHHHCCCCCHHEEECCCHHHHHHHHHHHHCCCCCCCCCC
TSDLGEDIMGRAAMPLLAGGTIVGVLVLYGNYQTLSNNIDWPSLVSMGSQIGIAIANTRL
CCCCCHHHHHHHHCHHHCCCHHHHHHHHCCCCHHHCCCCCCHHHHHCCCCCEEEEECCHH
YEESQRERQRLGTVIESIADGVAICNGVGELILANETAAGLVEISILPTLATSSESGARY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEEECCCCCCCEE
LDGTFVEADMLPFARALAGEVFRDYRLIVPGSQDQDVVLSFSGAPLRRSVLIDSTETSFD
CCCCEEEHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCC
GAVIVFRDITEQRRLEEAKDEFLAVAAHELRSPLAAIKGYSDLLLRRELKQASEGRDLRG
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEE
FITLSQQVNIMVQLVDNLLDVSRIDAERYTIQLDAVDLGILLDSVVTHARQTANNHTLHF
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEH
EQLNQSVVYGDSLKLRQVATNFLTNAIRYSPQQTNIWVQVFSDEQFGYVQVDDQGPGIPQ
HHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCCCCCCCC
GQRERLFERYYRVPGIRRTGSSTEGLGLGLYLCREIITLHNGRIWVDSAPSGGARFCIAI
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
PRFIPEKHETNTTQTTLDLDAFLFSPQPGRRNDE
HHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]