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The map label for this gene is resE [H]

Identifier: 159896813

GI number: 159896813

Start: 328713

End: 329921

Strand: Direct

Name: resE [H]

Synonym: Haur_0280

Alternate gene names: 159896813

Gene position: 328713-329921 (Clockwise)

Preceding gene: 159896812

Following gene: 159896814

Centisome position: 5.18

GC content: 52.03

Gene sequence:

>1209_bases
ATGAAGCCGAATGGGATGCAGATCTTATTCATTGACCATGATGGGCATGGCATACCCATTATTGCGTCGATCATCACGGC
AATTCAAACCGTCCAGTATCGCCTGATTGCGGTCTCCGACCTCCACCATGGCCTGAGTATGCTGGCAACTCGCCGGATCG
ATGCTATCTTGGTGCGACTGTCACTGACGGATAATACCGGCATGATCATCCAAACGCTGTCTGATCATGCATCAACCTAT
CCACTCATTCTCTCCTCCCCAAATACCGATGATCACACCTTGATCCCTATGCTGCACGGCGGGGTTCATGCCACGCTGTT
TGACGATGAACTTACGCCAGCACTGTTTCAGCGGACACTCGACTATGGGTTTGCCCGCGTCGCTCAATTAGCGGCAGAAG
ATCATGTCCAAACGCTCACCAGCACGCTGGCAGTGGCGCTTGATACAACCCATCAGATTGAACATCATCTGGCAATTGCG
ATTCATGAACTCCAAACGCCCATCAGTATTTTGCTCGGCTATATTGATCTATTTGAGCGACGAGTTGCGACATGGGGTGG
AATTCCCCTACGCGAACGGCAAATGATTAATACGATGCGGATGCAAGCGATTCATGTAGGACGATTGGTTCCAACGTTGC
TTGATAGCACGCTGATGACGCACGAGCTTGGGCCGATTCAGCGGCGTTCGCTTGAACTGAGTGCGGTGCTGCGAACGGTC
GTTGGAGCAATGCAAGGCATGCGAGCCTCGCATCTGTTGGTGTTGCGGGTGCCCGATGCAGCTGTATGGATTGAGGGCGA
TTATGGGCGCTTAGTTCAAATTTTTCAGAATCTCTTGCTCAATGCCCTGCACTATAGCGGCATGCATAGTGAAATTACCA
TCACCCTCGCTGCTGATGGGCAGATCACCATTCAGGATTATGGGGTCGGGATCTCCGCTGATGCCCTTGTGCAAATTGCG
CGTCCATTTTTTGACACTGCTGATCCCCATGGAGCGGCACGGATTGGTCAAGGACTTGGCTTGGCCATTGTGCAAGAACT
CATCCAGCAACACGAGGGCAGCATCACGATCGCCAGCACGGTAGATCATGGAACAACCATCACCATCCAATTTCCCTGGA
GTGTTCGGCCAACCCGTCTACCGGAACATCCTGCATCAATGCCGGTGAACTATCCCACCATTACTGATATTCAAGGGAGC
ACGCTATGA

Upstream 100 bases:

>100_bases
ACATATGGATGGCTTGGAATTAATTGTTGTTGTATGCACCCCTGTTGCTGTATGCACGTTCAATCAACCCGCTGGCTGCG
CCGCGAGATAGGATATTTTG

Downstream 100 bases:

>100_bases
AAAAACGTTCTGTTCTGCTCTGGCTAAGCCTGATTGGTGGGCTGATGCTACTGGGTAGTGCTAGCCCACAACCACAGGTG
ACGATTGGTGGTCTGACCAT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MKPNGMQILFIDHDGHGIPIIASIITAIQTVQYRLIAVSDLHHGLSMLATRRIDAILVRLSLTDNTGMIIQTLSDHASTY
PLILSSPNTDDHTLIPMLHGGVHATLFDDELTPALFQRTLDYGFARVAQLAAEDHVQTLTSTLAVALDTTHQIEHHLAIA
IHELQTPISILLGYIDLFERRVATWGGIPLRERQMINTMRMQAIHVGRLVPTLLDSTLMTHELGPIQRRSLELSAVLRTV
VGAMQGMRASHLLVLRVPDAAVWIEGDYGRLVQIFQNLLLNALHYSGMHSEITITLAADGQITIQDYGVGISADALVQIA
RPFFDTADPHGAARIGQGLGLAIVQELIQQHEGSITIASTVDHGTTITIQFPWSVRPTRLPEHPASMPVNYPTITDIQGS
TL

Sequences:

>Translated_402_residues
MKPNGMQILFIDHDGHGIPIIASIITAIQTVQYRLIAVSDLHHGLSMLATRRIDAILVRLSLTDNTGMIIQTLSDHASTY
PLILSSPNTDDHTLIPMLHGGVHATLFDDELTPALFQRTLDYGFARVAQLAAEDHVQTLTSTLAVALDTTHQIEHHLAIA
IHELQTPISILLGYIDLFERRVATWGGIPLRERQMINTMRMQAIHVGRLVPTLLDSTLMTHELGPIQRRSLELSAVLRTV
VGAMQGMRASHLLVLRVPDAAVWIEGDYGRLVQIFQNLLLNALHYSGMHSEITITLAADGQITIQDYGVGISADALVQIA
RPFFDTADPHGAARIGQGLGLAIVQELIQQHEGSITIASTVDHGTTITIQFPWSVRPTRLPEHPASMPVNYPTITDIQGS
TL
>Mature_402_residues
MKPNGMQILFIDHDGHGIPIIASIITAIQTVQYRLIAVSDLHHGLSMLATRRIDAILVRLSLTDNTGMIIQTLSDHASTY
PLILSSPNTDDHTLIPMLHGGVHATLFDDELTPALFQRTLDYGFARVAQLAAEDHVQTLTSTLAVALDTTHQIEHHLAIA
IHELQTPISILLGYIDLFERRVATWGGIPLRERQMINTMRMQAIHVGRLVPTLLDSTLMTHELGPIQRRSLELSAVLRTV
VGAMQGMRASHLLVLRVPDAAVWIEGDYGRLVQIFQNLLLNALHYSGMHSEITITLAADGQITIQDYGVGISADALVQIA
RPFFDTADPHGAARIGQGLGLAIVQELIQQHEGSITIASTVDHGTTITIQFPWSVRPTRLPEHPASMPVNYPTITDIQGS
TL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=30.9417040358744, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=26.8595041322314, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=27.2, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=27.8008298755187, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=214, Percent_Identity=26.1682242990654, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788549, Length=217, Percent_Identity=25.3456221198157, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=275, Percent_Identity=25.0909090909091, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=26.271186440678, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=219, Percent_Identity=24.2009132420091, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44087; Mature: 44087

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNGMQILFIDHDGHGIPIIASIITAIQTVQYRLIAVSDLHHGLSMLATRRIDAILVRL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHEEEEEEE
SLTDNTGMIIQTLSDHASTYPLILSSPNTDDHTLIPMLHGGVHATLFDDELTPALFQRTL
EECCCCCEEEEEHHCCCCCCCEEEECCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHH
DYGFARVAQLAAEDHVQTLTSTLAVALDTTHQIEHHLAIAIHELQTPISILLGYIDLFER
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVATWGGIPLRERQMINTMRMQAIHVGRLVPTLLDSTLMTHELGPIQRRSLELSAVLRTV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VGAMQGMRASHLLVLRVPDAAVWIEGDYGRLVQIFQNLLLNALHYSGMHSEITITLAADG
HHHHHCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
QITIQDYGVGISADALVQIARPFFDTADPHGAARIGQGLGLAIVQELIQQHEGSITIAST
EEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEEE
VDHGTTITIQFPWSVRPTRLPEHPASMPVNYPTITDIQGSTL
CCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure
MKPNGMQILFIDHDGHGIPIIASIITAIQTVQYRLIAVSDLHHGLSMLATRRIDAILVRL
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHEEEEEEE
SLTDNTGMIIQTLSDHASTYPLILSSPNTDDHTLIPMLHGGVHATLFDDELTPALFQRTL
EECCCCCEEEEEHHCCCCCCCEEEECCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHH
DYGFARVAQLAAEDHVQTLTSTLAVALDTTHQIEHHLAIAIHELQTPISILLGYIDLFER
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVATWGGIPLRERQMINTMRMQAIHVGRLVPTLLDSTLMTHELGPIQRRSLELSAVLRTV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VGAMQGMRASHLLVLRVPDAAVWIEGDYGRLVQIFQNLLLNALHYSGMHSEITITLAADG
HHHHHCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
QITIQDYGVGISADALVQIARPFFDTADPHGAARIGQGLGLAIVQELIQQHEGSITIAST
EEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEEE
VDHGTTITIQFPWSVRPTRLPEHPASMPVNYPTITDIQGSTL
CCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]