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The map label for this gene is rpoB

Identifier: 159896777

GI number: 159896777

Start: 282293

End: 285946

Strand: Reverse

Name: rpoB

Synonym: Haur_0244

Alternate gene names: 159896777

Gene position: 285946-282293 (Counterclockwise)

Preceding gene: 159896778

Following gene: 159896776

Centisome position: 4.51

GC content: 51.83

Gene sequence:

>3654_bases
ATGCCGCAAGTTCAGTCAACTGTTATCCTGCCACCGCTGATCACGTCCAGTATCTTCCGCGATGACCAAGGTCGTGCGAT
GATCGCATCACGTCGGAGTTTTGCTCGCATTACCGATGCGATTGAATTACCGAAGTTGATCGAAACCCAGATCGATTCGT
TTCGCTGGTTTCAACGTGAAGGGCTACGTGAATTGTTCGATGAAATTAATCCCATCGACGATTTCACGGGCAAAAACCTA
GAGCTTTCGTTTAGCGATTATGAGTTCGGCGAACCCCGCTATAACGAATTTGAGTGCCGTGAACGTGATATGACCTACGC
CGCCCCCCTGCGGGTTCGCGTGCGCTTGAAGGTCAAAACTACCGGTGAAATCAAGGAAAGCGATATCTTCCTTGGTGACT
TCCCATTGATGACCAATAATGGGACGTTTGTGATCAACGGCGCAGAACGGGTTGTTGTGTCGCAGTTGATTCGCTCACCT
GGCGTGTATTTCAAGGAAGAAAAAGAGCCAACCAGCGGTCGTTCGCTCCACAGTGCTAAGTTGATCCCCAACCGTGGTGC
TTGGCTGGAGTTTGAAACGAATAAGCGCGATGTGCTTTCGGTCAAGGTTGACCGCAAACGTAAGTTGCCAGTCACGATCT
TGATCCGCGCGGTGCTCGGCTTATTTGGCGATAAACCACTCGATCAATGTGGGCTGAATGAAGACGTTATCGCCTTATTC
GCCAATGTCGATGTTAACCGCGACCACCAATATATCGCTTCAACCTTGGATAAAGATCCATCAACCAATGCCAAAGAAGC
GATTATGGAATTGTACAAGCGCTTGCGCCCAGGCGATCCAGCAACTGTCGATAACGCCCGTTCGTTATTGGAAACCTTGC
TGTTCAACGCCCGCCGCTACGACTTGGGCAAAGTCGGTCGCTATAAATTAAATCGCAATCTGTGGGAAAAAAGCCGCCTC
TTCGAAGGCCAAGAAATTCCCAGCCTAACCATGCGCGTGCTCAGCAAAGCCGATTTGTTCAAAATCGTCGAGCGCTTGAT
CGATCTCAATAATGGGATTGGCAACCCCGATGATATTGACCACCTCGGTAACCGCCGCGTGCGGACTGTCGGCGAATTGA
TTCAAACCCAATTCCGCGTCGGTTTGCTGCGTATGGAACGGGTGATCAAAGAACGCATGTCGTTGCAAGAACCAGAAGCT
GCAACTCCCAATGGCTTGATCAATATCCGGCCTGTGGTTGCCGCTATGCGCGAGTTCTTCGGCGGTTCGCAACTTTCCCA
GTTCATGGATCAAACCAATCCATTGGCTGAGTTGACCCACAAACGCCGCCTTTCAGCGCTTGGCCCTGGTGGTCTGAGCC
GCGACCGTGCAGGCTTTGAGGTTCGCGACGTTCACCACTCGCACTATGGCCGGATCTGCCCGGTTGAAACGCCTGAAGGT
CCAAACATCGGTCTGATCGGTACGATGTCAACCTTTGCACGGGTTAACGAAATGGGCTTCCTTGAAACGCCCTATCGCCG
TGTCTATCGCGAAGTTGATAATGCCCCGCTCTGGCTTGAACGTGGCATGACTACCCGCGATGTGCGCCACCTCAGCACTG
GCGAGTTGATCGCTCGCGCTGGGGCACGGGTCGATGCTGAATTAGCCAAAATCATTGCGATCGGTGTGCTCAATGGACAA
TTGCTGCGTGAAGATATTGTCAACCCAGCGACTGGCGATTTGATTGCCGAAGCTGGTTCAGAAATTGACCGCGCCTTGGC
AACCAAAATTGCCGATTTGCCCTTACGTGCAATCAAAATTCACCCAGTTGTCACCAATGAAACCGACTATTTGCCAGCCG
ATGAAGAAGATAAGTTCATCATTGCCCAAGCTAACGCTTTGCTTGACGAACGCTTCCGCTTTATCGACCCAACGGTTTCA
TGCCGCCATGCTGAAGATTTCGTCCAAGCTCCAATCGCCTCGGTCGATTATATGGACGTTTCGCCCAAGCAGGTGGTCAG
TGTTTCAACCGCGTTGATTCCGTTCTTGGAACACGACGACGCAAACCGTGCCTTGATGGGTTCGAACATGCAGCGCCAAG
CTGTGCCGTTGTTGCGCCCTGATGCGCCAATTATCGGTACTGGCATGGAGCACAAAGCCGCCCGCGACTCAGGTCAGGTG
GTTGTGGCTCGTGCCGATGCTGTGGTGCTTTCATCGAATAGCGAACGCATTTTGGTTCGCGAAAACGATGGCACTGAACG
CACCTATCCATTGCTCAAGTTCTTGCGCTCGAACCAAGATACCTGTATCAACCAACGCCCAAGCGTCTTTATTGGCGATA
AAATTCGGGCTGGCGAGGTAATTGCCGATAGTTCTTCGACCCAAAATGGCGAGCTAGCGCTTGGCCAAAATATTCTCGTG
GCCTACATGCCTTGGGAAGGTGGGAACTTCGAAGACGCGATTTTGGTTAGCGAACGCTTGGTACGCGAAGATATTTTCAC
TTCGATTCACATTGAAAAATATGAAGTCGAAGCTCGCGATACCAAACTTGGCCCCGAAGAAATTACCCGCGATATTCCTA
ACGTCGGCCAAGATAGCCTTAAAAACTTGGACGAACGCGGGATTATCTATGTTGGTGCTGATGTTCAGCCAAACGATATT
TTGGTTGGCAAAATCACACCCAAGGGCGAAACTGACCTGACCGCTGAAGAACGGCTCTTGCGAGCTATCTTCGGTGAAAA
GGCCCGCGAAGTTAAAGATAGTAGCTTGCGCGTTCCCAACGGGGTCAAAGGTAAAGTCATTGATGTCAAGGTCTTTACCC
GCGACGAAACAACTGAAATGCCTGTCGGTGTCAATCAAACGGTGCGGGTGATGCTCTGTCAAAAGCGCAAAATCAGCCCA
GGCGATAAGATGGCAGGCCGCCACGGCAATAAAGGCGTGGTCAGCCGCGTGCTGCCAATCGAAGATATGCCATTCTTACC
CGATGGCACGCCTGTTGATATCGTCTTGAATCCGTTGGCGGTGCCAAGCCGCATGAACATCGGCCAGATTTTGGAAACTC
ACTTGGGTTGGGCTGCTTCACGCTTGGGCTTCCGTATCGCCACGCCAGTCTTCGACGGCGCACGCGATGAGGATATTATC
AAAGCTCTCGCTGAATCAGGCCTGCCATCCGATGCCAAGATCGATCTCTACGATGGCCGCACTGGCGAGAAATTCGATAA
TCCAGTGACCGTCGGTTACAAATATATGCTCAAGTTGGCGCACTTGGTGGAAGATAAGATCCACGCTCGCTCAACTGGCC
CTTACAGCTTGGTGACTCAACAGCCACTCGGCGGTAAGGCTCAGTTCGGTGGTCAGCGCTTTGGTGAAATGGAAGTTTGG
GCGCTCGAAGCCTATGGCGCTGCTTACATTCTCCAAGAAATGCTCACGGTCAAGTCCGACGACGTGGTTGGTCGGGTCAA
AACGTATGAGGCGATCGTCAAGGGCGATCCAATCAACGAAGCCGGCGTACCTGAATCGTTCAAGGTCTTGATCAAAGAGT
TGCAATCGCTTGGTCTGTCGGTCGATGTGTTGACCGCTGATGAACGCCCGGTTGAGCTAACCGATAGCGAAGCCGATGAC
TTAATCTCACTCGACGGCATCAACCTGTCGGGGATGGAAAAAGGCGAACTCTAA

Upstream 100 bases:

>100_bases
GCAGTCAAACTCGCAGCCGGACAACCACAAGTCGCATTTTTGACTACGGGTGTTTGGAGGTGAGCATTTTGTGCTTTTGC
GGGGCTAGGGAGCGAAGCTG

Downstream 100 bases:

>100_bases
ACTTCGGTTGCGATCCATTGCTCTCGCGGTAGTTCCCAATGACGTGAACTACCGCCTCTCTATCGCACGGTGCTAACCAT
GGCTCGACCTGCTGCTAGCA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1217; Mature: 1216

Protein sequence:

>1217_residues
MPQVQSTVILPPLITSSIFRDDQGRAMIASRRSFARITDAIELPKLIETQIDSFRWFQREGLRELFDEINPIDDFTGKNL
ELSFSDYEFGEPRYNEFECRERDMTYAAPLRVRVRLKVKTTGEIKESDIFLGDFPLMTNNGTFVINGAERVVVSQLIRSP
GVYFKEEKEPTSGRSLHSAKLIPNRGAWLEFETNKRDVLSVKVDRKRKLPVTILIRAVLGLFGDKPLDQCGLNEDVIALF
ANVDVNRDHQYIASTLDKDPSTNAKEAIMELYKRLRPGDPATVDNARSLLETLLFNARRYDLGKVGRYKLNRNLWEKSRL
FEGQEIPSLTMRVLSKADLFKIVERLIDLNNGIGNPDDIDHLGNRRVRTVGELIQTQFRVGLLRMERVIKERMSLQEPEA
ATPNGLINIRPVVAAMREFFGGSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRICPVETPEG
PNIGLIGTMSTFARVNEMGFLETPYRRVYREVDNAPLWLERGMTTRDVRHLSTGELIARAGARVDAELAKIIAIGVLNGQ
LLREDIVNPATGDLIAEAGSEIDRALATKIADLPLRAIKIHPVVTNETDYLPADEEDKFIIAQANALLDERFRFIDPTVS
CRHAEDFVQAPIASVDYMDVSPKQVVSVSTALIPFLEHDDANRALMGSNMQRQAVPLLRPDAPIIGTGMEHKAARDSGQV
VVARADAVVLSSNSERILVRENDGTERTYPLLKFLRSNQDTCINQRPSVFIGDKIRAGEVIADSSSTQNGELALGQNILV
AYMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEARDTKLGPEEITRDIPNVGQDSLKNLDERGIIYVGADVQPNDI
LVGKITPKGETDLTAEERLLRAIFGEKAREVKDSSLRVPNGVKGKVIDVKVFTRDETTEMPVGVNQTVRVMLCQKRKISP
GDKMAGRHGNKGVVSRVLPIEDMPFLPDGTPVDIVLNPLAVPSRMNIGQILETHLGWAASRLGFRIATPVFDGARDEDII
KALAESGLPSDAKIDLYDGRTGEKFDNPVTVGYKYMLKLAHLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVW
ALEAYGAAYILQEMLTVKSDDVVGRVKTYEAIVKGDPINEAGVPESFKVLIKELQSLGLSVDVLTADERPVELTDSEADD
LISLDGINLSGMEKGEL

Sequences:

>Translated_1217_residues
MPQVQSTVILPPLITSSIFRDDQGRAMIASRRSFARITDAIELPKLIETQIDSFRWFQREGLRELFDEINPIDDFTGKNL
ELSFSDYEFGEPRYNEFECRERDMTYAAPLRVRVRLKVKTTGEIKESDIFLGDFPLMTNNGTFVINGAERVVVSQLIRSP
GVYFKEEKEPTSGRSLHSAKLIPNRGAWLEFETNKRDVLSVKVDRKRKLPVTILIRAVLGLFGDKPLDQCGLNEDVIALF
ANVDVNRDHQYIASTLDKDPSTNAKEAIMELYKRLRPGDPATVDNARSLLETLLFNARRYDLGKVGRYKLNRNLWEKSRL
FEGQEIPSLTMRVLSKADLFKIVERLIDLNNGIGNPDDIDHLGNRRVRTVGELIQTQFRVGLLRMERVIKERMSLQEPEA
ATPNGLINIRPVVAAMREFFGGSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRICPVETPEG
PNIGLIGTMSTFARVNEMGFLETPYRRVYREVDNAPLWLERGMTTRDVRHLSTGELIARAGARVDAELAKIIAIGVLNGQ
LLREDIVNPATGDLIAEAGSEIDRALATKIADLPLRAIKIHPVVTNETDYLPADEEDKFIIAQANALLDERFRFIDPTVS
CRHAEDFVQAPIASVDYMDVSPKQVVSVSTALIPFLEHDDANRALMGSNMQRQAVPLLRPDAPIIGTGMEHKAARDSGQV
VVARADAVVLSSNSERILVRENDGTERTYPLLKFLRSNQDTCINQRPSVFIGDKIRAGEVIADSSSTQNGELALGQNILV
AYMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEARDTKLGPEEITRDIPNVGQDSLKNLDERGIIYVGADVQPNDI
LVGKITPKGETDLTAEERLLRAIFGEKAREVKDSSLRVPNGVKGKVIDVKVFTRDETTEMPVGVNQTVRVMLCQKRKISP
GDKMAGRHGNKGVVSRVLPIEDMPFLPDGTPVDIVLNPLAVPSRMNIGQILETHLGWAASRLGFRIATPVFDGARDEDII
KALAESGLPSDAKIDLYDGRTGEKFDNPVTVGYKYMLKLAHLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVW
ALEAYGAAYILQEMLTVKSDDVVGRVKTYEAIVKGDPINEAGVPESFKVLIKELQSLGLSVDVLTADERPVELTDSEADD
LISLDGINLSGMEKGEL
>Mature_1216_residues
PQVQSTVILPPLITSSIFRDDQGRAMIASRRSFARITDAIELPKLIETQIDSFRWFQREGLRELFDEINPIDDFTGKNLE
LSFSDYEFGEPRYNEFECRERDMTYAAPLRVRVRLKVKTTGEIKESDIFLGDFPLMTNNGTFVINGAERVVVSQLIRSPG
VYFKEEKEPTSGRSLHSAKLIPNRGAWLEFETNKRDVLSVKVDRKRKLPVTILIRAVLGLFGDKPLDQCGLNEDVIALFA
NVDVNRDHQYIASTLDKDPSTNAKEAIMELYKRLRPGDPATVDNARSLLETLLFNARRYDLGKVGRYKLNRNLWEKSRLF
EGQEIPSLTMRVLSKADLFKIVERLIDLNNGIGNPDDIDHLGNRRVRTVGELIQTQFRVGLLRMERVIKERMSLQEPEAA
TPNGLINIRPVVAAMREFFGGSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRICPVETPEGP
NIGLIGTMSTFARVNEMGFLETPYRRVYREVDNAPLWLERGMTTRDVRHLSTGELIARAGARVDAELAKIIAIGVLNGQL
LREDIVNPATGDLIAEAGSEIDRALATKIADLPLRAIKIHPVVTNETDYLPADEEDKFIIAQANALLDERFRFIDPTVSC
RHAEDFVQAPIASVDYMDVSPKQVVSVSTALIPFLEHDDANRALMGSNMQRQAVPLLRPDAPIIGTGMEHKAARDSGQVV
VARADAVVLSSNSERILVRENDGTERTYPLLKFLRSNQDTCINQRPSVFIGDKIRAGEVIADSSSTQNGELALGQNILVA
YMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEARDTKLGPEEITRDIPNVGQDSLKNLDERGIIYVGADVQPNDIL
VGKITPKGETDLTAEERLLRAIFGEKAREVKDSSLRVPNGVKGKVIDVKVFTRDETTEMPVGVNQTVRVMLCQKRKISPG
DKMAGRHGNKGVVSRVLPIEDMPFLPDGTPVDIVLNPLAVPSRMNIGQILETHLGWAASRLGFRIATPVFDGARDEDIIK
ALAESGLPSDAKIDLYDGRTGEKFDNPVTVGYKYMLKLAHLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWA
LEAYGAAYILQEMLTVKSDDVVGRVKTYEAIVKGDPINEAGVPESFKVLIKELQSLGLSVDVLTADERPVELTDSEADDL
ISLDGINLSGMEKGEL

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908503, Length=1221, Percent_Identity=22.8501228501229, Blast_Score=193, Evalue=1e-48,
Organism=Homo sapiens, GI238908505, Length=1154, Percent_Identity=23.1369150779896, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI4505941, Length=414, Percent_Identity=30.4347826086957, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI33469941, Length=421, Percent_Identity=28.978622327791, Blast_Score=146, Evalue=1e-34,
Organism=Homo sapiens, GI212286172, Length=421, Percent_Identity=28.978622327791, Blast_Score=146, Evalue=1e-34,
Organism=Escherichia coli, GI1790419, Length=342, Percent_Identity=60.233918128655, Blast_Score=403, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI25144348, Length=1242, Percent_Identity=24.0740740740741, Blast_Score=201, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17552304, Length=548, Percent_Identity=26.4598540145985, Blast_Score=166, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17506623, Length=184, Percent_Identity=36.9565217391304, Blast_Score=124, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6324725, Length=422, Percent_Identity=29.8578199052133, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324781, Length=416, Percent_Identity=29.3269230769231, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6325267, Length=355, Percent_Identity=30.1408450704225, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI17136444, Length=413, Percent_Identity=30.9927360774818, Blast_Score=161, Evalue=3e-39,
Organism=Drosophila melanogaster, GI17647877, Length=423, Percent_Identity=29.5508274231678, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17136446, Length=424, Percent_Identity=27.3584905660377, Blast_Score=117, Evalue=6e-26,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_HERA2 (A9B6J3)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001543024.1
- ProteinModelPortal:   A9B6J3
- GeneID:   5732139
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_0244
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- BioCyc:   HAUR316274:HAUR_0244-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 135541; Mature: 135409

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQVQSTVILPPLITSSIFRDDQGRAMIASRRSFARITDAIELPKLIETQIDSFRWFQRE
CCCCCCEEEECHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRELFDEINPIDDFTGKNLELSFSDYEFGEPRYNEFECRERDMTYAAPLRVRVRLKVKT
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHCCCEEECCEEEEEEEEEEE
TGEIKESDIFLGDFPLMTNNGTFVINGAERVVVSQLIRSPGVYFKEEKEPTSGRSLHSAK
CCCCCCCCEEEECCCEEECCCEEEECCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEE
LIPNRGAWLEFETNKRDVLSVKVDRKRKLPVTILIRAVLGLFGDKPLDQCGLNEDVIALF
ECCCCCCEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCEEEE
ANVDVNRDHQYIASTLDKDPSTNAKEAIMELYKRLRPGDPATVDNARSLLETLLFNARRY
ECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
DLGKVGRYKLNRNLWEKSRLFEGQEIPSLTMRVLSKADLFKIVERLIDLNNGIGNPDDID
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
HLGNRRVRTVGELIQTQFRVGLLRMERVIKERMSLQEPEAATPNGLINIRPVVAAMREFF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHH
GGSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRICPVETPEG
CCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
PNIGLIGTMSTFARVNEMGFLETPYRRVYREVDNAPLWLERGMTTRDVRHLSTGELIARA
CCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHHCCHHHHHHHC
GARVDAELAKIIAIGVLNGQLLREDIVNPATGDLIAEAGSEIDRALATKIADLPLRAIKI
CCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEE
HPVVTNETDYLPADEEDKFIIAQANALLDERFRFIDPTVSCRHAEDFVQAPIASVDYMDV
EEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
SPKQVVSVSTALIPFLEHDDANRALMGSNMQRQAVPLLRPDAPIIGTGMEHKAARDSGQV
CHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCCEEECCCCHHCCCCCCCE
VVARADAVVLSSNSERILVRENDGTERTYPLLKFLRSNQDTCINQRPSVFIGDKIRAGEV
EEEECCEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCE
IADSSSTQNGELALGQNILVAYMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEARD
EECCCCCCCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCC
TKLGPEEITRDIPNVGQDSLKNLDERGIIYVGADVQPNDILVGKITPKGETDLTAEERLL
CCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHH
RAIFGEKAREVKDSSLRVPNGVKGKVIDVKVFTRDETTEMPVGVNQTVRVMLCQKRKISP
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHEEHHCCCCCC
GDKMAGRHGNKGVVSRVLPIEDMPFLPDGTPVDIVLNPLAVPSRMNIGQILETHLGWAAS
CHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
RLGFRIATPVFDGARDEDIIKALAESGLPSDAKIDLYDGRTGEKFDNPVTVGYKYMLKLA
HCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
HLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYILQEMLTVKSD
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCC
DVVGRVKTYEAIVKGDPINEAGVPESFKVLIKELQSLGLSVDVLTADERPVELTDSEADD
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCCCCC
LISLDGINLSGMEKGEL
EEEECCCCCCCCCCCCC
>Mature Secondary Structure 
PQVQSTVILPPLITSSIFRDDQGRAMIASRRSFARITDAIELPKLIETQIDSFRWFQRE
CCCCCEEEECHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRELFDEINPIDDFTGKNLELSFSDYEFGEPRYNEFECRERDMTYAAPLRVRVRLKVKT
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHCCCEEECCEEEEEEEEEEE
TGEIKESDIFLGDFPLMTNNGTFVINGAERVVVSQLIRSPGVYFKEEKEPTSGRSLHSAK
CCCCCCCCEEEECCCEEECCCEEEECCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEE
LIPNRGAWLEFETNKRDVLSVKVDRKRKLPVTILIRAVLGLFGDKPLDQCGLNEDVIALF
ECCCCCCEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCEEEE
ANVDVNRDHQYIASTLDKDPSTNAKEAIMELYKRLRPGDPATVDNARSLLETLLFNARRY
ECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
DLGKVGRYKLNRNLWEKSRLFEGQEIPSLTMRVLSKADLFKIVERLIDLNNGIGNPDDID
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
HLGNRRVRTVGELIQTQFRVGLLRMERVIKERMSLQEPEAATPNGLINIRPVVAAMREFF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHH
GGSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRICPVETPEG
CCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
PNIGLIGTMSTFARVNEMGFLETPYRRVYREVDNAPLWLERGMTTRDVRHLSTGELIARA
CCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHHCCHHHHHHHC
GARVDAELAKIIAIGVLNGQLLREDIVNPATGDLIAEAGSEIDRALATKIADLPLRAIKI
CCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEE
HPVVTNETDYLPADEEDKFIIAQANALLDERFRFIDPTVSCRHAEDFVQAPIASVDYMDV
EEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCC
SPKQVVSVSTALIPFLEHDDANRALMGSNMQRQAVPLLRPDAPIIGTGMEHKAARDSGQV
CHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCCEEECCCCHHCCCCCCCE
VVARADAVVLSSNSERILVRENDGTERTYPLLKFLRSNQDTCINQRPSVFIGDKIRAGEV
EEEECCEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCE
IADSSSTQNGELALGQNILVAYMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEARD
EECCCCCCCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCC
TKLGPEEITRDIPNVGQDSLKNLDERGIIYVGADVQPNDILVGKITPKGETDLTAEERLL
CCCCHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHH
RAIFGEKAREVKDSSLRVPNGVKGKVIDVKVFTRDETTEMPVGVNQTVRVMLCQKRKISP
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHEEHHCCCCCC
GDKMAGRHGNKGVVSRVLPIEDMPFLPDGTPVDIVLNPLAVPSRMNIGQILETHLGWAAS
CHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
RLGFRIATPVFDGARDEDIIKALAESGLPSDAKIDLYDGRTGEKFDNPVTVGYKYMLKLA
HCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
HLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYILQEMLTVKSD
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCC
DVVGRVKTYEAIVKGDPINEAGVPESFKVLIKELQSLGLSVDVLTADERPVELTDSEADD
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCCCCC
LISLDGINLSGMEKGEL
EEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA