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The map label for this gene is trpB [H]

Identifier: 159896755

GI number: 159896755

Start: 258893

End: 260092

Strand: Reverse

Name: trpB [H]

Synonym: Haur_0222

Alternate gene names: 159896755

Gene position: 260092-258893 (Counterclockwise)

Preceding gene: 159896756

Following gene: 159896754

Centisome position: 4.1

GC content: 52.17

Gene sequence:

>1200_bases
ATGACCGATCACGCTGTTCTTGATGAATTAAATGGCCGCTATGGGGATTTCGGTGGACGCTATGTGCCAGAAACCTTGAT
GGCCGCGATCGAAGAATTAACCGAAGCCTTTTTTCGGATTCGCACCGACCCTGAGTTTCAGGCTGAACTCCAACATTTGC
ACCAGACCTATACGGGCCGACCAACTGCCCTCACCTATGCCCGCCGCTTGACCGAGGAATTGGGTGGTGCTCAAATTTGG
CTCAAACGCGAAGACCTGACCCACACTGGCGCACATAAAATCAATAATGCCTTAGGGCAAGGCTTGTTGGCCAAACGCAT
GGGCAAACAGCGGATCATCGCTGAAACTGGCGCTGGCCAGCATGGCGTTGCTACCGCTGCCGTTTGTGCCCTGCTTGGGC
TGCAATGTGTGGTCTATATGGGCACCGAAGATATGGAGCGCCAAAAGCCCAATGTCTTTCGTATGCGCTTGCTGGGAGCC
GATGTGCGTGGAGTCAGCACTGGCTCGAAAACCCTCAAAGATGCAGTTAACGAAGCCATGCGCGATTGGGTCAGCAACCC
CGATTCGTACTATTTGCTTGGCTCGGCGCTTGGCCCACACCCTTATCCATTGATGGTACGCGAATTTCAAAGCATCATCG
GAATTGAAGCCCGCGAGCAAATTTTAGCAGCAACTGGCAAATTGCCCAACACGATTATTGCTTGCGTTGGGGGTGGCTCG
AACGCAATCGGGATGTTCCACGCCTTTATCAACGATGAACATGTTGATTTGCGAGGAGTTGAAGCTGGTGGTCATGGAAT
TGAGCTTGGTCGCCATGCAGCGCGGTTTGCAGGCGGGCGCTTGGGCGTTTTCCAAGGCACCCGTTCGTATGTGCTGCAAA
ATAGCGATGGCCAAATTGCCAATACCCATAGCATTTCTGCTGGTCTCGATTATGCTGCTGTAGGCCCAGAGCACGCTTGG
CTCCACGACGAGGAACGGGCTTTCTATACCTATGCCACCGACGAAGAGGCCTTGAATGGTTTTCAAATGCTCTGTCGAAC
TGAAGGCATTATCCCAGCCTTAGAATCGTCGCATGCGATTGCCGAAGCTGTACGTTTAGCCCCAACCATGAGCAAAGAAA
GCATTATTTTGGTCAATCTGTCGGGGCGTGGCGATAAAGATATTTTCACCGTTGCAGATGTATTGGGAGTGCAAATGTAG

Upstream 100 bases:

>100_bases
CCACGCCAAGGCGATGATTACACTTGGTGGCTGATCGAATCGGCAATTGGCCAAGGTTGGGTTGCTGAAGATTTTATTCA
AGCACGCTAAAGGAACAATT

Downstream 100 bases:

>100_bases
CGGAATGGCTTCGAGCGAAGCCAATGTGTAAGGAGTAGTTATGGCTCAATCGTGTGTCGTTTGTCGAGCCGCGCTTGCCG
ATGGCTCGGTCTATTGTTCT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTDHAVLDELNGRYGDFGGRYVPETLMAAIEELTEAFFRIRTDPEFQAELQHLHQTYTGRPTALTYARRLTEELGGAQIW
LKREDLTHTGAHKINNALGQGLLAKRMGKQRIIAETGAGQHGVATAAVCALLGLQCVVYMGTEDMERQKPNVFRMRLLGA
DVRGVSTGSKTLKDAVNEAMRDWVSNPDSYYLLGSALGPHPYPLMVREFQSIIGIEAREQILAATGKLPNTIIACVGGGS
NAIGMFHAFINDEHVDLRGVEAGGHGIELGRHAARFAGGRLGVFQGTRSYVLQNSDGQIANTHSISAGLDYAAVGPEHAW
LHDEERAFYTYATDEEALNGFQMLCRTEGIIPALESSHAIAEAVRLAPTMSKESIILVNLSGRGDKDIFTVADVLGVQM

Sequences:

>Translated_399_residues
MTDHAVLDELNGRYGDFGGRYVPETLMAAIEELTEAFFRIRTDPEFQAELQHLHQTYTGRPTALTYARRLTEELGGAQIW
LKREDLTHTGAHKINNALGQGLLAKRMGKQRIIAETGAGQHGVATAAVCALLGLQCVVYMGTEDMERQKPNVFRMRLLGA
DVRGVSTGSKTLKDAVNEAMRDWVSNPDSYYLLGSALGPHPYPLMVREFQSIIGIEAREQILAATGKLPNTIIACVGGGS
NAIGMFHAFINDEHVDLRGVEAGGHGIELGRHAARFAGGRLGVFQGTRSYVLQNSDGQIANTHSISAGLDYAAVGPEHAW
LHDEERAFYTYATDEEALNGFQMLCRTEGIIPALESSHAIAEAVRLAPTMSKESIILVNLSGRGDKDIFTVADVLGVQM
>Mature_398_residues
TDHAVLDELNGRYGDFGGRYVPETLMAAIEELTEAFFRIRTDPEFQAELQHLHQTYTGRPTALTYARRLTEELGGAQIWL
KREDLTHTGAHKINNALGQGLLAKRMGKQRIIAETGAGQHGVATAAVCALLGLQCVVYMGTEDMERQKPNVFRMRLLGAD
VRGVSTGSKTLKDAVNEAMRDWVSNPDSYYLLGSALGPHPYPLMVREFQSIIGIEAREQILAATGKLPNTIIACVGGGSN
AIGMFHAFINDEHVDLRGVEAGGHGIELGRHAARFAGGRLGVFQGTRSYVLQNSDGQIANTHSISAGLDYAAVGPEHAWL
HDEERAFYTYATDEEALNGFQMLCRTEGIIPALESSHAIAEAVRLAPTMSKESIILVNLSGRGDKDIFTVADVLGVQM

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=388, Percent_Identity=58.7628865979381, Blast_Score=460, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6321412, Length=398, Percent_Identity=57.035175879397, Blast_Score=459, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43391; Mature: 43260

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHAVLDELNGRYGDFGGRYVPETLMAAIEELTEAFFRIRTDPEFQAELQHLHQTYTGR
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PTALTYARRLTEELGGAQIWLKREDLTHTGAHKINNALGQGLLAKRMGKQRIIAETGAGQ
CHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCC
HGVATAAVCALLGLQCVVYMGTEDMERQKPNVFRMRLLGADVRGVSTGSKTLKDAVNEAM
CCHHHHHHHHHHHHHEEEEECCCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
RDWVSNPDSYYLLGSALGPHPYPLMVREFQSIIGIEAREQILAATGKLPNTIIACVGGGS
HHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCC
NAIGMFHAFINDEHVDLRGVEAGGHGIELGRHAARFAGGRLGVFQGTRSYVLQNSDGQIA
CHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCEE
NTHSISAGLDYAAVGPEHAWLHDEERAFYTYATDEEALNGFQMLCRTEGIIPALESSHAI
ECCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHH
AEAVRLAPTMSKESIILVNLSGRGDKDIFTVADVLGVQM
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TDHAVLDELNGRYGDFGGRYVPETLMAAIEELTEAFFRIRTDPEFQAELQHLHQTYTGR
CCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PTALTYARRLTEELGGAQIWLKREDLTHTGAHKINNALGQGLLAKRMGKQRIIAETGAGQ
CHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCC
HGVATAAVCALLGLQCVVYMGTEDMERQKPNVFRMRLLGADVRGVSTGSKTLKDAVNEAM
CCHHHHHHHHHHHHHEEEEECCCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
RDWVSNPDSYYLLGSALGPHPYPLMVREFQSIIGIEAREQILAATGKLPNTIIACVGGGS
HHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCC
NAIGMFHAFINDEHVDLRGVEAGGHGIELGRHAARFAGGRLGVFQGTRSYVLQNSDGQIA
CHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCEE
NTHSISAGLDYAAVGPEHAWLHDEERAFYTYATDEEALNGFQMLCRTEGIIPALESSHAI
ECCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHH
AEAVRLAPTMSKESIILVNLSGRGDKDIFTVADVLGVQM
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA