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The map label for this gene is moaE [H]

Identifier: 159896693

GI number: 159896693

Start: 189961

End: 190377

Strand: Direct

Name: moaE [H]

Synonym: Haur_0160

Alternate gene names: 159896693

Gene position: 189961-190377 (Clockwise)

Preceding gene: 159896692

Following gene: 159896694

Centisome position: 2.99

GC content: 56.12

Gene sequence:

>417_bases
GTGCAAGCATTTTTGGTAACCGAGGCAGTTTTGCAACCCGAGCCGTTGCGCCAGTTGGTCAGCGACCCCGGCCATGGGGC
GATTGTGCTGTTTGAAGGCGTGGCTCGCAATAACTTTGGTGGGCGAGCTACGGCCTACTTGGAGTACGAAGCCTATCCCG
AGATGGCTGAGCAGCAACTAGTCTTGTTGGCGCGGCAAGCCCAAGTCCAATTTGGCATTGGCAAGGTCGCGATTCACCAT
CGGGTTGGCGTGTTGCAAATTGGCGAAACTGCCGTGCTGATTGCAATTGGCTCGGCCCATCGTGGCGCGGCATTTGCTGC
GGTGGCTTGGCTGATGGATCAAATCAAGGTGGTTGTGCCAATTTGGAAATGTGAGCACTGGACCGATGGTTCGCAAGAAT
GGGTGGGTCAGCGTTGA

Upstream 100 bases:

>100_bases
GGCTTAGCGTATGCGATCAATCGCCAATATGTGACGCTTGAGGCGACGCTTCAGCCCAACGACGAACTGGCCTTGATTCC
GCCAGTGAGTGGGGGCTAGA

Downstream 100 bases:

>100_bases
AGCACTAAGGTGAGCTATGCGATTGCTCGAAAAACTAGCACGATGGTGGTGGCGTTGGCTTCTAACAACAATTAGTTTGT
TGGGCACGGCGCTGCTTGGC

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MQAFLVTEAVLQPEPLRQLVSDPGHGAIVLFEGVARNNFGGRATAYLEYEAYPEMAEQQLVLLARQAQVQFGIGKVAIHH
RVGVLQIGETAVLIAIGSAHRGAAFAAVAWLMDQIKVVVPIWKCEHWTDGSQEWVGQR

Sequences:

>Translated_138_residues
MQAFLVTEAVLQPEPLRQLVSDPGHGAIVLFEGVARNNFGGRATAYLEYEAYPEMAEQQLVLLARQAQVQFGIGKVAIHH
RVGVLQIGETAVLIAIGSAHRGAAFAAVAWLMDQIKVVVPIWKCEHWTDGSQEWVGQR
>Mature_138_residues
MQAFLVTEAVLQPEPLRQLVSDPGHGAIVLFEGVARNNFGGRATAYLEYEAYPEMAEQQLVLLARQAQVQFGIGKVAIHH
RVGVLQIGETAVLIAIGSAHRGAAFAAVAWLMDQIKVVVPIWKCEHWTDGSQEWVGQR

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=128, Percent_Identity=39.0625, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1787003, Length=138, Percent_Identity=34.0579710144928, Blast_Score=80, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17509279, Length=131, Percent_Identity=35.8778625954198, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356259, Length=121, Percent_Identity=36.3636363636364, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 15144; Mature: 15144

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAFLVTEAVLQPEPLRQLVSDPGHGAIVLFEGVARNNFGGRATAYLEYEAYPEMAEQQL
CCCEEEHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHH
VLLARQAQVQFGIGKVAIHHRVGVLQIGETAVLIAIGSAHRGAAFAAVAWLMDQIKVVVP
HHHHHHHHHEECCCEEEEECCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHEEEEE
IWKCEHWTDGSQEWVGQR
EEECCCCCCCCHHHCCCC
>Mature Secondary Structure
MQAFLVTEAVLQPEPLRQLVSDPGHGAIVLFEGVARNNFGGRATAYLEYEAYPEMAEQQL
CCCEEEHHHHCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCHHHHHHHH
VLLARQAQVQFGIGKVAIHHRVGVLQIGETAVLIAIGSAHRGAAFAAVAWLMDQIKVVVP
HHHHHHHHHEECCCEEEEECCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHEEEEE
IWKCEHWTDGSQEWVGQR
EEECCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]