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The map label for this gene is ucpA [C]

Identifier: 159896665

GI number: 159896665

Start: 162737

End: 163438

Strand: Direct

Name: ucpA [C]

Synonym: Haur_0132

Alternate gene names: 159896665

Gene position: 162737-163438 (Clockwise)

Preceding gene: 159896664

Following gene: 159896666

Centisome position: 2.56

GC content: 53.28

Gene sequence:

>702_bases
ATGACTAAAACAATGGTGATTACTGGAGCTGGCCGTGGGATTGGCCGGGCAATTGCCTTGGCCTGTGCCGCCAACAACCA
ACTGGTTTTGCTCGCTCGCAGCGCAGCTGAATTGCAAGCAGTTGCCATTGAAATCCAATCGGCTGGTGGAACGGCGCAGG
TTGTGGTTGGCAATGCTAGCGATCCAGCGATTGTGCAACAGGCAATTGATCTGGCGCAGCAAGCGGGCCAAGGTCACATC
GATGGGCTGATTTTGGCGGCGGGGGTGGCTCACGTGGCCCACGTTGGCGCGTTAAGTTTACAGCAATGGCAACAATCGTT
GGATGTTAATTTAACTGCCAGCTTTTTGGCATGTCAAGCAGCATTGCCCTATCTCAAGGCTGGCAGCCAAATTATTGCGA
TTTCGTCGATTGCTGGCAAAAGTGGCTTTCCAGGTTGGGCGGCCTATTCAGCAAGCAAATTTGGCTTGATGGGCTTTTTG
CAGGCTTTACGCGAAGAACTGCGCCCGCAGGGAGTACGAGTGACGGCAGTCGTTTCGGCGGCGGTTGATACTGCCTTGTG
GAACGACGTGGCAGGCAGTTGGAACCGCCAAAATATGTTGCAAGCCAGCGAAGTTGCCAACGCGGTTGCCCATATTTTGA
GCCAACCAAGCCATGTACTGATCGACGAGATCAGTATTGGCCATGTGGTCGGTAAATTGTAA

Upstream 100 bases:

>100_bases
GCCAACGCTCGCATGGTCACGCAATCGTTGCAAGGTGTGTTTAAAACCGATCCGCAAATTCGCGCTGAATTTATGGGTCA
TATCACGGCGAATTTTTCCG

Downstream 100 bases:

>100_bases
GCAACAAAAAACCGAGGCGGTAAATGCCGCCTCGGCTTACTCTGGAAGCCCCAGATTGAGAATGGTCGAGCATCAAACTG
AAAGGCTGCGATGTGCGATG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTKTMVITGAGRGIGRAIALACAANNQLVLLARSAAELQAVAIEIQSAGGTAQVVVGNASDPAIVQQAIDLAQQAGQGHI
DGLILAAGVAHVAHVGALSLQQWQQSLDVNLTASFLACQAALPYLKAGSQIIAISSIAGKSGFPGWAAYSASKFGLMGFL
QALREELRPQGVRVTAVVSAAVDTALWNDVAGSWNRQNMLQASEVANAVAHILSQPSHVLIDEISIGHVVGKL

Sequences:

>Translated_233_residues
MTKTMVITGAGRGIGRAIALACAANNQLVLLARSAAELQAVAIEIQSAGGTAQVVVGNASDPAIVQQAIDLAQQAGQGHI
DGLILAAGVAHVAHVGALSLQQWQQSLDVNLTASFLACQAALPYLKAGSQIIAISSIAGKSGFPGWAAYSASKFGLMGFL
QALREELRPQGVRVTAVVSAAVDTALWNDVAGSWNRQNMLQASEVANAVAHILSQPSHVLIDEISIGHVVGKL
>Mature_232_residues
TKTMVITGAGRGIGRAIALACAANNQLVLLARSAAELQAVAIEIQSAGGTAQVVVGNASDPAIVQQAIDLAQQAGQGHID
GLILAAGVAHVAHVGALSLQQWQQSLDVNLTASFLACQAALPYLKAGSQIIAISSIAGKSGFPGWAAYSASKFGLMGFLQ
ALREELRPQGVRVTAVVSAAVDTALWNDVAGSWNRQNMLQASEVANAVAHILSQPSHVLIDEISIGHVVGKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32455239, Length=196, Percent_Identity=34.6938775510204, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI5031765, Length=196, Percent_Identity=34.6938775510204, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI40254992, Length=232, Percent_Identity=29.7413793103448, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4503817, Length=223, Percent_Identity=28.2511210762332, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI142976729, Length=224, Percent_Identity=28.125, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=27.1604938271605, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI32483357, Length=200, Percent_Identity=31.5, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI40254986, Length=238, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=231, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787335, Length=232, Percent_Identity=28.8793103448276, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789378, Length=236, Percent_Identity=27.1186440677966, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787526, Length=192, Percent_Identity=31.7708333333333, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=185, Percent_Identity=33.5135135135135, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=230, Percent_Identity=32.6086956521739, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71982365, Length=197, Percent_Identity=29.9492385786802, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=205, Percent_Identity=33.1707317073171, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17558628, Length=248, Percent_Identity=31.4516129032258, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=169, Percent_Identity=29.585798816568, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=197, Percent_Identity=26.9035532994924, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=26.9035532994924, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=186, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=187, Percent_Identity=26.2032085561497, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=236, Percent_Identity=28.8135593220339, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322226, Length=191, Percent_Identity=30.3664921465969, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=212, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.7935222672065, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571526, Length=220, Percent_Identity=30.9090909090909, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI116007236, Length=235, Percent_Identity=30.6382978723404, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI23397609, Length=231, Percent_Identity=32.4675324675325, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357041, Length=219, Percent_Identity=29.2237442922374, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=179, Percent_Identity=33.5195530726257, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357673, Length=219, Percent_Identity=27.8538812785388, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355319, Length=190, Percent_Identity=27.8947368421053, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859837, Length=171, Percent_Identity=34.5029239766082, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23915; Mature: 23784

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTMVITGAGRGIGRAIALACAANNQLVLLARSAAELQAVAIEIQSAGGTAQVVVGNAS
CCCEEEEEECCCCHHHHHEEEEECCCCEEEEECCCHHEEEEEEEEECCCCEEEEEEECCC
DPAIVQQAIDLAQQAGQGHIDGLILAAGVAHVAHVGALSLQQWQQSLDVNLTASFLACQA
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALPYLKAGSQIIAISSIAGKSGFPGWAAYSASKFGLMGFLQALREELRPQGVRVTAVVSA
HHHHHHCCCEEEEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHH
AVDTALWNDVAGSWNRQNMLQASEVANAVAHILSQPSHVLIDEISIGHVVGKL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCC
>Mature Secondary Structure 
TKTMVITGAGRGIGRAIALACAANNQLVLLARSAAELQAVAIEIQSAGGTAQVVVGNAS
CCEEEEEECCCCHHHHHEEEEECCCCEEEEECCCHHEEEEEEEEECCCCEEEEEEECCC
DPAIVQQAIDLAQQAGQGHIDGLILAAGVAHVAHVGALSLQQWQQSLDVNLTASFLACQA
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALPYLKAGSQIIAISSIAGKSGFPGWAAYSASKFGLMGFLQALREELRPQGVRVTAVVSA
HHHHHHCCCEEEEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHH
AVDTALWNDVAGSWNRQNMLQASEVANAVAHILSQPSHVLIDEISIGHVVGKL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1905979; 11679669 [H]