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The map label for this gene is uidR [H]

Identifier: 159896551

GI number: 159896551

Start: 22004

End: 22594

Strand: Reverse

Name: uidR [H]

Synonym: Haur_0018

Alternate gene names: 159896551

Gene position: 22594-22004 (Counterclockwise)

Preceding gene: 159896553

Following gene: 159896550

Centisome position: 0.36

GC content: 48.73

Gene sequence:

>591_bases
ATGAGCAACAAAGCCCAAGCTCGCCAGCGCCAAATCTTGGATGCAGCAGCGATCTGTTTTGCACGGCGCGGCTTTCATCA
GACCACCATGGACGATATTTGTCGCGAAGTTCAGCTTAGCCCAGGCTCGGTCTATCGCTACTATCGCAGCAAAGATGAAA
TTATCGCGGCTTTTGTCGAAGACGATAGCCGCGATATGAGCGACTTGTTGCGTCAAGTTGGTGCTCTGCCAAATTTATGG
CAAGGGCTGGATTGGCTGGTTGATCAGTTGGTGGCAGCCATTAATTCACCGCTGTATGCTGAGCTTAGCGCCGAAATTGG
CTCGGAAACCATACATAATCCACGGATTGCCAGCTTGGTTCGGCAGAGCGATCAGGCCAATCATCAAGCATTGATTGAAT
TATTCAGTCTGGCGCAACAGCGTGGGCAATTACCAACCGATTTAGATTTGCCGCAGATCGCCGATTTAATCATTATGCTG
ATCGATGGACTAACTTGGCGCAAGGGTTTGTATCCGGAACATGATTTAACCCTATATGCCGCTGGCCTCAAACACACGAT
TAAATATCTGTTGTCTGGCACTCGATTTTAA

Upstream 100 bases:

>100_bases
TTGATTCCTTCGTTGATCACTCTAGACAAAATAGCTTCTTTCTTATAAAATGCGAATGAACGTTCATTCGCATTTTCCTA
GCTAGGAGTTTAATTTGGCT

Downstream 100 bases:

>100_bases
TTGCGGGAATTCATGGCACTTGGAGAGGTATTATGGCAATTGTATCCCGTTCCAAGACCACAAATGTGGTCAAAGATTCG
CAACGGATTGTTGGTTATGA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: Uid operon repressor [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSNKAQARQRQILDAAAICFARRGFHQTTMDDICREVQLSPGSVYRYYRSKDEIIAAFVEDDSRDMSDLLRQVGALPNLW
QGLDWLVDQLVAAINSPLYAELSAEIGSETIHNPRIASLVRQSDQANHQALIELFSLAQQRGQLPTDLDLPQIADLIIML
IDGLTWRKGLYPEHDLTLYAAGLKHTIKYLLSGTRF

Sequences:

>Translated_196_residues
MSNKAQARQRQILDAAAICFARRGFHQTTMDDICREVQLSPGSVYRYYRSKDEIIAAFVEDDSRDMSDLLRQVGALPNLW
QGLDWLVDQLVAAINSPLYAELSAEIGSETIHNPRIASLVRQSDQANHQALIELFSLAQQRGQLPTDLDLPQIADLIIML
IDGLTWRKGLYPEHDLTLYAAGLKHTIKYLLSGTRF
>Mature_195_residues
SNKAQARQRQILDAAAICFARRGFHQTTMDDICREVQLSPGSVYRYYRSKDEIIAAFVEDDSRDMSDLLRQVGALPNLWQ
GLDWLVDQLVAAINSPLYAELSAEIGSETIHNPRIASLVRQSDQANHQALIELFSLAQQRGQLPTDLDLPQIADLIIMLI
DGLTWRKGLYPEHDLTLYAAGLKHTIKYLLSGTRF

Specific function: Repressor for the uidRABC (gusRABC) operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787904, Length=166, Percent_Identity=25.3012048192771, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22126; Mature: 21994

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKAQARQRQILDAAAICFARRGFHQTTMDDICREVQLSPGSVYRYYRSKDEIIAAFVE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHC
DDSRDMSDLLRQVGALPNLWQGLDWLVDQLVAAINSPLYAELSAEIGSETIHNPRIASLV
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHCCCHHHHHHH
RQSDQANHQALIELFSLAQQRGQLPTDLDLPQIADLIIMLIDGLTWRKGLYPEHDLTLYA
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHH
AGLKHTIKYLLSGTRF
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNKAQARQRQILDAAAICFARRGFHQTTMDDICREVQLSPGSVYRYYRSKDEIIAAFVE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHC
DDSRDMSDLLRQVGALPNLWQGLDWLVDQLVAAINSPLYAELSAEIGSETIHNPRIASLV
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHCCCHHHHHHH
RQSDQANHQALIELFSLAQQRGQLPTDLDLPQIADLIIMLIDGLTWRKGLYPEHDLTLYA
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHH
AGLKHTIKYLLSGTRF
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]