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The map label for this gene is pgcA [H]

Identifier: 15928070

GI number: 15928070

Start: 2555052

End: 2556803

Strand: Direct

Name: pgcA [H]

Synonym: SA2279

Alternate gene names: 15928070

Gene position: 2555052-2556803 (Clockwise)

Preceding gene: 15928058

Following gene: 15928071

Centisome position: 90.77

GC content: 33.5

Gene sequence:

>1752_bases
GTGTTTTTTTACTTTTGGGGCGTATTTCTTTATAATTCATTACATAAATGTAAGGGCTTTAGTTTTCATGTTTTATTAAG
TCTAACTGAGATTTTGAAAGGATGTTTAGCAACAATGGATAAAGAATTATGGATAGAAAGAGCTAATGATAGTTTAGTTA
AACATTTTTATGAGCAGCAATCTGACATTGAACAGCGAGAAGGTTTTGAAAGTAAATTAACATTTGGTACTGCGGGTATA
CGCGGAAAATTCGGTCTTGGTGAAGGTCGACTTAATAAGTTTACTATTGAAAAATTGGCATTAGGTTTAGCGCGTTATTT
AAATGCCCAAACAAACAGTCCAACAATAGTCATTCATTATGATATTAGACATCTTTCAACTGAATTCGCCCAAATTATTG
CTAATGTATTAGCAAACCATCAAATAACAGTTTATTTACCTGATACATATAAAACGACACCGGAATTATCGTTCGCGGTT
CGCAATCTTAATACTACTGCCGGCATTATGATTACAGCAAGTCATAATCCGAAAGACTATAACGGCATTAAAGTATATGG
TTCTGATGGCGCGCAATTATCGACTGATGCATCTGAGCTTGCAAGTCGTTATATCGAAGAAGTTGGCGATCCATTACAGA
TTGATATACCTATTTCAAAACAAAATACATCTTATATCAAACCTTTTCCGAAATCTGTAACTGATGACTATATGAAACAC
ATTCAAAATATGATTGGCTATATTCCTAAATCTGATTTACAAGTTGTGTTCACTAGTTTGCATGGTACAAGTGTTCCAAT
TGTACCTGAGTTATTAAAATCTTTGAATTTCAATCAATTTAATCTTGTAGATGCACAATGTAAACCTGATCCGAATTTTA
GTTCAGTTCAAAGTGCTAATCCTGAAGATCATCGCGCTTTTGATCAAGCAGTCGAACTTGCAAATAAAAGTCATGCAGAC
TTATTAATATCAACTGACCCAGATGCAGATCGACTTGGTATTGCTGAACGTGATGCACATGGTCATATCACATATTTTAA
TGGCAACCAAATTGGTGCGCTGTTACTTAATTATCGTATTCAACAAACGTCTCAATTACGTCACCGCTTAATGATTCAAT
CTATTGTAAGTAGTGAGTTAACAAAGTCATTAGCACGCTATAATAATGTTAAATACAAAGAGGTACTGACGGGCTTTAAA
TTTATTGCTCAGGAAATAAGACAACTGGATGATCATCAAAATATGATTTTCGCATTTGAAGAGAGTTACGGTTTTCTATC
AGAGCCTTTTGTACGTGATAAAGATGCCGTACAAATTGTGCCACTCATTATAAAATACGCTTCTGAGTTAAAATTATATG
GCAAAACATTGAAAGATGAATTAGAACAGATTTATCAAACTGTTGGTAGACATGAGGATACATTATTCTCGCATACGCTA
GAAGGATTAGAAGGTAAGAAAAAAATTGAATCAATTATGACACATTTCCGTTCAAATCCACCGCAAGAGATTCAAGGACT
GAAAGTGAAAGCAATTGAAGATTATTTAACTAGCGAGGTTTATCATTTGGATAAAGATACAACGTCACAGATTAATTCTT
CTAAATCAAATGTTATTCGTGTCTTATTTGACGAAGGATTTATCGCTTTACGTCCTTCTGGTACTGAACCTAAAATTAAA
TTATATGTGTCGTTAAAATGTCCGGATTTTGATGATGTAGCTCAAAAAATTAATGCGATGATTTTTAGCTAA

Upstream 100 bases:

>100_bases
TTTTACAATTTCCTGCATGATATATCACTCTTACATCTACTCCATGCATTTTCATACACATCTATTATATAATACTTGTG
AAAAGTATTGTCTTGGGGCT

Downstream 100 bases:

>100_bases
TTAAAAATTTTATACATCGAAATATTACATTTCATTTTATACTTATCAGCCCTTTTGAAACTAGAATCCTTATGTTTTCG
CGTTTTGAAGGGGCTAATTT

Product: hypothetical protein

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGI
RGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAV
RNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKH
IQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHAD
LLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFK
FIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTL
EGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSSKSNVIRVLFDEGFIALRPSGTEPKIK
LYVSLKCPDFDDVAQKINAMIFS

Sequences:

>Translated_583_residues
MFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGI
RGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAV
RNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKH
IQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHAD
LLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFK
FIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTL
EGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSSKSNVIRVLFDEGFIALRPSGTEPKIK
LYVSLKCPDFDDVAQKINAMIFS
>Mature_583_residues
MFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGI
RGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAV
RNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKH
IQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHAD
LLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFK
FIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTL
EGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSSKSNVIRVLFDEGFIALRPSGTEPKIK
LYVSLKCPDFDDVAQKINAMIFS

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also use

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=583, Percent_Identity=32.590051457976, Blast_Score=255, Evalue=1e-67,
Organism=Homo sapiens, GI31377548, Length=549, Percent_Identity=32.2404371584699, Blast_Score=230, Evalue=2e-60,
Organism=Escherichia coli, GI1789566, Length=302, Percent_Identity=28.8079470198675, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788361, Length=264, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71993870, Length=559, Percent_Identity=29.8747763864043, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71993878, Length=321, Percent_Identity=31.1526479750779, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323934, Length=552, Percent_Identity=27.7173913043478, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI20129809, Length=563, Percent_Identity=29.4849023090586, Blast_Score=222, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24651977, Length=537, Percent_Identity=28.4916201117318, Blast_Score=205, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24653722, Length=533, Percent_Identity=29.0806754221388, Blast_Score=188, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 66099; Mature: 66099

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQ
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHH
SDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHY
HHHHHHCCCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDY
CHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHEECCCCCEEEEEEECCCCCCC
NGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKH
CCEEEECCCCCEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
IQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPNFSSVQSAN
HHHHHHCCCCCCHHEEEECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
PEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRI
CHHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCCCCCCCCCEEEEECCCCCEEHHHHHHH
QQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
ESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSSKSNVIR
HCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEE
VLFDEGFIALRPSGTEPKIKLYVSLKCPDFDDVAQKINAMIFS
EEEECCEEEECCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQ
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHH
SDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHY
HHHHHHCCCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDY
CHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHEECCCCCEEEEEEECCCCCCC
NGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKH
CCEEEECCCCCEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
IQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPNFSSVQSAN
HHHHHHCCCCCCHHEEEECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
PEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRI
CHHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCCCCCCCCCEEEEECCCCCEEHHHHHHH
QQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
ESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSSKSNVIR
HCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEE
VLFDEGFIALRPSGTEPKIKLYVSLKCPDFDDVAQKINAMIFS
EEEECCEEEECCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA