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The map label for this gene is melR [C]

Identifier: 15927959

GI number: 15927959

Start: 2437337

End: 2439442

Strand: Direct

Name: melR [C]

Synonym: SA2169

Alternate gene names: 15927959

Gene position: 2437337-2439442 (Clockwise)

Preceding gene: 15927958

Following gene: 15927960

Centisome position: 86.59

GC content: 28.58

Gene sequence:

>2106_bases
ATGACATGCCAACTTAAAATACATCATACATTATCGACAATACCAAGTCGTAATATTAATAATATTATGGTGCTATTTTC
ACTTACAAGTAAACTCAATATTACGATTAATGGTGAAACCAAAGACGTAAGTAATTATATTATCTTAATTAACCATGGTG
ATATTTATAATATTAACCACGGCGAAAATATAATCGAATTAATGATACCCGTTTTTTATTTTTATCAACAAGATGATGAT
TTCTTTAATGGTTATTTAGATCGTCATTTATTACAATCAAGTAATTATATTAAGTCATTAATTGCCGATTTAATCAGTAC
ACCAACAAGTTCTTCTTTAATGGGGAAAAATATAGGTCAAAGTATTATAGACACTTTACTTAAAGAAGCTTTTATAAGAA
TAGATCATGAATATTTACCAAATATTGCTTTAAGCAATCCGGTGTTCATAGACTGTGTAAACTATATTCATGACAATATT
GATGCGCACTTGTCTTTAAAAGATATAGCGATGCATTGCAACATCTCTGAATCATATTGTTCTAATCTTTTTGTTCGATA
TTTGAGTATGAATTTTAAAGATTATTTTACAAGTATTAAACTTGTTAACGCCATCAATTTATTACTTTCTACAAAACATT
CTATTACAACTGTTTCTGAATTGGCCGGTTTTAACAGTCATACAAATTTTGCAAATCAATTTAAGAATTACTTGCATTTT
AGTCCTAAACAGTTCCGTTCACTCGTTTCCAAGATTACTGAACCACCACAAATACACTTCCAACAAGATAACGTATCACA
ATTCACTGAGTTAATTTCAACAATTGATTTAACAGCTCAACTGGCTACAAATACAACAGATATTCATATAGATGATTTTA
ATCCGAAAGATCGAAGTCAGCGTGCCAAAGTATTTGTTCGATTTAGTAATTTCAATGAACTATTTCAATTTATTTTCAAT
GAATATTACGATATTAACTTTGAGCACTTACCAAAACCTGTCGTTTTCATTGACGATATTCACGATATTGAGATTAGCCA
AACGAATTACAACCTGTTAAATAGATGTTTTGAAAAGCTTTTCGAAAAAAATATAGGTTTAGCAATCGCTATTAAATCAA
CACAACAATTCGAAACGATGAAGCAGTTAATACTAACATTTTTACAAGGCAATCAAGACTATAAGACAAGCAAGAAATTA
GTTAAATTTATGCTCGTATTTTGCTCTAATTCTATGACAGCAGAAGAAATTCATTTATGTCATCTTAAAATTAAAAACAA
AAATAAAGAAATTAAATATAGTGTGACAGTCGATGGCTTTTTAGAAACTTATTCAACCGTGGAACAAGTTTATGATGTCA
TGCAGCGTCTTAAATTCCATTATTACTTTATTGATATTGAAAATTCAAAAACTGCAACACATCTTATCACTAAAAACCAA
CACTATCATCAAACTGACACTCATTTTGAACAGTATAAGAAATTTATTTTAGATTCAGGTATATCATCAACACAATTTGT
ATATAATAACCTGTCTGTAAGCGGATTTAAATATACTAATGATGGTAAGAATCCAATTCAATTATCTGACATAGTGTATC
ACTTAATCGCATTATTACGATATGGCGGTGGCATTAGCTATCAATTATTAGATGACCATTCAAATTATATTTCCTTGTAC
AACAAATATGGTAGCCCCCTACCATTAATGCATTTATATAAAATGTTTAGACCTTTTGTTAATGAAGATATTGAAATTAC
AAATAATTATGTATTGAGTCGTAAAGATAATAACTACCATTTCTTATTATTCAATAAAATTAATGATCGATATATGTCAG
ACGTAAAACAAGATTTCATTTTCCATAATGAATTACCTCAAGACTCTTTGATGATTATTAAAACATTGAATCATGAACAT
GGTTCAATTCAACATTTGCTTCCAATAAGCGATCAACTTGTTTATATAGAAAAAGAAATTTTAGATGAATTAGACAAAAC
GAATTACCCTAAAACGGAGCTTGCAGTTCAAGAAGAAACTGGTCGTACATTTGAACTCAAGTTAAATCACGACGAGGTTA
AATATATTTGCTTTAAACCAAGCTAA

Upstream 100 bases:

>100_bases
ATATTCAACTATAATAGGTATACTATCCATGATTTTAAAAATTTCCATGTTTTACATTTAAATGATAGATTTCAATATAT
ATTAGGCAGGAGAGAGAAAT

Downstream 100 bases:

>100_bases
ATACTAACAGTCCTCTTGTGTTTAGTTTCTTACGTTAAAGGCTATTTATATCATAAGGAGATGATATGTAATGAGTAACT
CACAAGCAATTCAAGCAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 700

Protein sequence:

>701_residues
MTCQLKIHHTLSTIPSRNINNIMVLFSLTSKLNITINGETKDVSNYIILINHGDIYNINHGENIIELMIPVFYFYQQDDD
FFNGYLDRHLLQSSNYIKSLIADLISTPTSSSLMGKNIGQSIIDTLLKEAFIRIDHEYLPNIALSNPVFIDCVNYIHDNI
DAHLSLKDIAMHCNISESYCSNLFVRYLSMNFKDYFTSIKLVNAINLLLSTKHSITTVSELAGFNSHTNFANQFKNYLHF
SPKQFRSLVSKITEPPQIHFQQDNVSQFTELISTIDLTAQLATNTTDIHIDDFNPKDRSQRAKVFVRFSNFNELFQFIFN
EYYDINFEHLPKPVVFIDDIHDIEISQTNYNLLNRCFEKLFEKNIGLAIAIKSTQQFETMKQLILTFLQGNQDYKTSKKL
VKFMLVFCSNSMTAEEIHLCHLKIKNKNKEIKYSVTVDGFLETYSTVEQVYDVMQRLKFHYYFIDIENSKTATHLITKNQ
HYHQTDTHFEQYKKFILDSGISSTQFVYNNLSVSGFKYTNDGKNPIQLSDIVYHLIALLRYGGGISYQLLDDHSNYISLY
NKYGSPLPLMHLYKMFRPFVNEDIEITNNYVLSRKDNNYHFLLFNKINDRYMSDVKQDFIFHNELPQDSLMIIKTLNHEH
GSIQHLLPISDQLVYIEKEILDELDKTNYPKTELAVQEETGRTFELKLNHDEVKYICFKPS

Sequences:

>Translated_701_residues
MTCQLKIHHTLSTIPSRNINNIMVLFSLTSKLNITINGETKDVSNYIILINHGDIYNINHGENIIELMIPVFYFYQQDDD
FFNGYLDRHLLQSSNYIKSLIADLISTPTSSSLMGKNIGQSIIDTLLKEAFIRIDHEYLPNIALSNPVFIDCVNYIHDNI
DAHLSLKDIAMHCNISESYCSNLFVRYLSMNFKDYFTSIKLVNAINLLLSTKHSITTVSELAGFNSHTNFANQFKNYLHF
SPKQFRSLVSKITEPPQIHFQQDNVSQFTELISTIDLTAQLATNTTDIHIDDFNPKDRSQRAKVFVRFSNFNELFQFIFN
EYYDINFEHLPKPVVFIDDIHDIEISQTNYNLLNRCFEKLFEKNIGLAIAIKSTQQFETMKQLILTFLQGNQDYKTSKKL
VKFMLVFCSNSMTAEEIHLCHLKIKNKNKEIKYSVTVDGFLETYSTVEQVYDVMQRLKFHYYFIDIENSKTATHLITKNQ
HYHQTDTHFEQYKKFILDSGISSTQFVYNNLSVSGFKYTNDGKNPIQLSDIVYHLIALLRYGGGISYQLLDDHSNYISLY
NKYGSPLPLMHLYKMFRPFVNEDIEITNNYVLSRKDNNYHFLLFNKINDRYMSDVKQDFIFHNELPQDSLMIIKTLNHEH
GSIQHLLPISDQLVYIEKEILDELDKTNYPKTELAVQEETGRTFELKLNHDEVKYICFKPS
>Mature_700_residues
TCQLKIHHTLSTIPSRNINNIMVLFSLTSKLNITINGETKDVSNYIILINHGDIYNINHGENIIELMIPVFYFYQQDDDF
FNGYLDRHLLQSSNYIKSLIADLISTPTSSSLMGKNIGQSIIDTLLKEAFIRIDHEYLPNIALSNPVFIDCVNYIHDNID
AHLSLKDIAMHCNISESYCSNLFVRYLSMNFKDYFTSIKLVNAINLLLSTKHSITTVSELAGFNSHTNFANQFKNYLHFS
PKQFRSLVSKITEPPQIHFQQDNVSQFTELISTIDLTAQLATNTTDIHIDDFNPKDRSQRAKVFVRFSNFNELFQFIFNE
YYDINFEHLPKPVVFIDDIHDIEISQTNYNLLNRCFEKLFEKNIGLAIAIKSTQQFETMKQLILTFLQGNQDYKTSKKLV
KFMLVFCSNSMTAEEIHLCHLKIKNKNKEIKYSVTVDGFLETYSTVEQVYDVMQRLKFHYYFIDIENSKTATHLITKNQH
YHQTDTHFEQYKKFILDSGISSTQFVYNNLSVSGFKYTNDGKNPIQLSDIVYHLIALLRYGGGISYQLLDDHSNYISLYN
KYGSPLPLMHLYKMFRPFVNEDIEITNNYVLSRKDNNYHFLLFNKINDRYMSDVKQDFIFHNELPQDSLMIIKTLNHEHG
SIQHLLPISDQLVYIEKEILDELDKTNYPKTELAVQEETGRTFELKLNHDEVKYICFKPS

Specific function: Transcription Activator For The Expression Of The Melab Operon. Melr Binds At Two Sites Located Upstream Of The Melab Transcription Site. [C]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HTH araC/xylS-type DNA-binding domains [H]

Homologues:

Organism=Escherichia coli, GI1790559, Length=96, Percent_Identity=31.25, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 81883; Mature: 81752

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCQLKIHHTLSTIPSRNINNIMVLFSLTSKLNITINGETKDVSNYIILINHGDIYNINH
CEEEEEEHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCEEEEEECCCEEECCC
GENIIELMIPVFYFYQQDDDFFNGYLDRHLLQSSNYIKSLIADLISTPTSSSLMGKNIGQ
CCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHCCH
SIIDTLLKEAFIRIDHEYLPNIALSNPVFIDCVNYIHDNIDAHLSLKDIAMHCNISESYC
HHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHEEEECCCCHHHH
SNLFVRYLSMNFKDYFTSIKLVNAINLLLSTKHSITTVSELAGFNSHTNFANQFKNYLHF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCC
SPKQFRSLVSKITEPPQIHFQQDNVSQFTELISTIDLTAQLATNTTDIHIDDFNPKDRSQ
CHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCC
RAKVFVRFSNFNELFQFIFNEYYDINFEHLPKPVVFIDDIHDIEISQTNYNLLNRCFEKL
EEEEEEEECCHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHH
FEKNIGLAIAIKSTQQFETMKQLILTFLQGNQDYKTSKKLVKFMLVFCSNSMTAEEIHLC
HHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHEEEE
HLKIKNKNKEIKYSVTVDGFLETYSTVEQVYDVMQRLKFHYYFIDIENSKTATHLITKNQ
EEEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCEEEEEECCC
HYHQTDTHFEQYKKFILDSGISSTQFVYNNLSVSGFKYTNDGKNPIQLSDIVYHLIALLR
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCEECCEEECCCCCCCEEHHHHHHHHHHHHH
YGGGISYQLLDDHSNYISLYNKYGSPLPLMHLYKMFRPFVNEDIEITNNYVLSRKDNNYH
HCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCEEEEEECCCEE
FLLFNKINDRYMSDVKQDFIFHNELPQDSLMIIKTLNHEHGSIQHLLPISDQLVYIEKEI
EEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEHHH
LDELDKTNYPKTELAVQEETGRTFELKLNHDEVKYICFKPS
HHHHHCCCCCCHHEEEECCCCCEEEEEECCCCEEEEEECCC
>Mature Secondary Structure 
TCQLKIHHTLSTIPSRNINNIMVLFSLTSKLNITINGETKDVSNYIILINHGDIYNINH
EEEEEEHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCEEEEEECCCEEECCC
GENIIELMIPVFYFYQQDDDFFNGYLDRHLLQSSNYIKSLIADLISTPTSSSLMGKNIGQ
CCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHCCH
SIIDTLLKEAFIRIDHEYLPNIALSNPVFIDCVNYIHDNIDAHLSLKDIAMHCNISESYC
HHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHEEEECCCCHHHH
SNLFVRYLSMNFKDYFTSIKLVNAINLLLSTKHSITTVSELAGFNSHTNFANQFKNYLHF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCC
SPKQFRSLVSKITEPPQIHFQQDNVSQFTELISTIDLTAQLATNTTDIHIDDFNPKDRSQ
CHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCC
RAKVFVRFSNFNELFQFIFNEYYDINFEHLPKPVVFIDDIHDIEISQTNYNLLNRCFEKL
EEEEEEEECCHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHH
FEKNIGLAIAIKSTQQFETMKQLILTFLQGNQDYKTSKKLVKFMLVFCSNSMTAEEIHLC
HHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHEEEE
HLKIKNKNKEIKYSVTVDGFLETYSTVEQVYDVMQRLKFHYYFIDIENSKTATHLITKNQ
EEEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCEEEEEECCC
HYHQTDTHFEQYKKFILDSGISSTQFVYNNLSVSGFKYTNDGKNPIQLSDIVYHLIALLR
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCEECCEEECCCCCCCEEHHHHHHHHHHHHH
YGGGISYQLLDDHSNYISLYNKYGSPLPLMHLYKMFRPFVNEDIEITNNYVLSRKDNNYH
HCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCEEEEEECCCEE
FLLFNKINDRYMSDVKQDFIFHNELPQDSLMIIKTLNHEHGSIQHLLPISDQLVYIEKEI
EEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEHHH
LDELDKTNYPKTELAVQEETGRTFELKLNHDEVKYICFKPS
HHHHHCCCCCCHHEEEECCCCCEEEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12044378 [H]