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The map label for this gene is acuC

Identifier: 15927312

GI number: 15927312

Start: 1782927

End: 1784096

Strand: Direct

Name: acuC

Synonym: SA1556

Alternate gene names: 15927312

Gene position: 1782927-1784096 (Clockwise)

Preceding gene: 15927311

Following gene: 15927323

Centisome position: 63.34

GC content: 34.7

Gene sequence:

>1170_bases
ATGCAACAACATTCATCAAAAACTGCATATGTTTATTCAGATAAGTTATTACAATATCGATTTCATGACCAACATCCCTT
CAATCAAATGCGTTTAAAATTAACAACAGAGCTACTTTTGAATGCAAATTTATTGTCTCCAGAACAAATAGTACAACCTA
GAATTGCAACAGGTGACGAATTAATGTTAATTCATAAATATGATTACGTCGAAGCTATTAAGCATGCTTCACATGGCATT
ATCAGTGAAGATGAGGCTAAGAAATATGGATTAAATGATGAAGAGAATGGTCAATTTAAGCATATGCACCGCCATAGTGC
CACAATTGTTGGAGGCGCTTTAACTTTAGCAGATCTTATTATGTCAGGCAAAGTATTAAATGGTTGTCACTTAGGTGGTG
GTTTGCATCACGCTCAACCTGGTCGAGCAAGTGGTTTTTGTATATACAATGATATTGCAATTACCGCACAATACATAGCT
AAAGAATACAATCAACGCGTTTTAATCATAGATACCGATGCACATCATGGAGATGGTACACAATGGAGTTTCTATGCCGA
TAACCATGTTACTACTTATTCTATCCATGAAACCGGAAAGTTTCTTTTCCCAGGCTCTGGTCACTATACTGAACGCGGTG
AAGATATCGGCTATGGACACACTGTAAATGTCCCACTTGAACCGTATACAGAAGATGCATCATTTTTGGAGTGTTTTAAA
TTAACAGTTGAGCCTGTCGTAAAGAGTTTTAAACCTGATATTATTCTAAGCGTAAATGGTGTCGATATACATTATCGTGA
TCCACTAACTCATCTAAATTGTACGTTACATTCATTATATGAAATTCCATATTTTGTAAAATATTTAGCTGATTCTTATA
CGAATGGAAAGGTAATTATGTTTGGTGGCGGAGGCTACAATATTTGGAGAGTCGTACCACGTGCATGGAGTCATGTATTC
TTAAGTTTAATTGATCAACCAATTCAAAGTGGTTATTTACCGTTAGAATGGATTAATAAATGGAAACATTATTCATCTGA
ATTATTACCTAAAAGATGGGAAGATCGTTTAAATGATTATACCTATGTCCCCCGCACAAAAGAAATTAGTGAAAAAAATA
AAAAATTAGCTTTACATATAGCGAGTTGGTACGAATCTACTCGTCAATAA

Upstream 100 bases:

>100_bases
AATTGGCAAAAATATTACATTAGAACAGCAACAAGCGTTTGATGATATTCGTTATATGAATCGGTTTTTCTTTTAATTTT
TGGAATATCGGAGGGATTAT

Downstream 100 bases:

>100_bases
GTAACCTAATCTGCAACGATTTTAAAAGATAAATAAAAGGCATTCTTCCAACACCCATATAATTTGGGTCGTTAGATGAA
TGCCTAATTTTGTGAATTTA

Product: acetoin utilization protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ

Sequences:

>Translated_389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ
>Mature_389_residues
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDELMLIHKYDYVEAIKHASHGI
ISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIA
KEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVF
LSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ

Specific function: Role in growth on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=328, Percent_Identity=31.7073170731707, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI13128862, Length=388, Percent_Identity=28.0927835051546, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI17158039, Length=340, Percent_Identity=29.4117647058824, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI30795204, Length=340, Percent_Identity=29.4117647058824, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI30795202, Length=340, Percent_Identity=29.4117647058824, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI293336691, Length=323, Percent_Identity=30.9597523219814, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI13128864, Length=377, Percent_Identity=28.1167108753316, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI8923769, Length=310, Percent_Identity=26.1290322580645, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI62750349, Length=337, Percent_Identity=29.9703264094956, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI62750347, Length=337, Percent_Identity=29.9703264094956, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI153085395, Length=213, Percent_Identity=31.4553990610329, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI20070354, Length=272, Percent_Identity=28.6764705882353, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI169234807, Length=134, Percent_Identity=39.5522388059701, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI148539870, Length=134, Percent_Identity=39.5522388059701, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI262073092, Length=208, Percent_Identity=27.8846153846154, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI262073088, Length=224, Percent_Identity=26.7857142857143, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI226529806, Length=238, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI209862883, Length=289, Percent_Identity=23.8754325259516, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI217272877, Length=290, Percent_Identity=24.8275862068966, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17561978, Length=385, Percent_Identity=29.8701298701299, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17508561, Length=337, Percent_Identity=28.7833827893175, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17534739, Length=318, Percent_Identity=29.874213836478, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193209491, Length=241, Percent_Identity=33.195020746888, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540334, Length=312, Percent_Identity=29.8076923076923, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=30.0653594771242, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=30.0653594771242, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17537347, Length=285, Percent_Identity=28.4210526315789, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI25154020, Length=356, Percent_Identity=25, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25154022, Length=368, Percent_Identity=24.4565217391304, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321244, Length=322, Percent_Identity=31.9875776397516, Blast_Score=156, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6323999, Length=313, Percent_Identity=28.7539936102236, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324307, Length=335, Percent_Identity=28.3582089552239, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325325, Length=227, Percent_Identity=29.0748898678414, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24657891, Length=321, Percent_Identity=33.3333333333333, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24644244, Length=336, Percent_Identity=30.6547619047619, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24642144, Length=339, Percent_Identity=27.4336283185841, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24642142, Length=339, Percent_Identity=27.4336283185841, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24642146, Length=339, Percent_Identity=27.4336283185841, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281360899, Length=346, Percent_Identity=27.1676300578035, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281360799, Length=201, Percent_Identity=34.8258706467662, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI281360801, Length=201, Percent_Identity=34.8258706467662, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24641720, Length=339, Percent_Identity=28.9085545722714, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24649807, Length=291, Percent_Identity=27.4914089347079, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 44572; Mature: 44572

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDE
CCCCCCCEEEEEECHHEEEEECCCCCHHHHHHHEEEHHHHCCCCCCHHHHHCCCCCCCCC
LMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLI
EEEEEECHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHCCCEEEHHHHHHHHHH
MSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIAKEYNQRVLIIDTDAHHGDGT
HCCCEECCEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
QWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
EEEEEECCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIM
HHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
FGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDY
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCC
TYVPRTKEISEKNKKLALHIASWYESTRQ
EECCCCHHHHCCCCEEEEEEEHHHHHHCC
>Mature Secondary Structure
MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDE
CCCCCCCEEEEEECHHEEEEECCCCCHHHHHHHEEEHHHHCCCCCCHHHHHCCCCCCCCC
LMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLI
EEEEEECHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHCCCEEEHHHHHHHHHH
MSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIAKEYNQRVLIIDTDAHHGDGT
HCCCEECCEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCCC
QWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGYGHTVNVPLEPYTEDASFLECFK
EEEEEECCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHH
LTVEPVVKSFKPDIILSVNGVDIHYRDPLTHLNCTLHSLYEIPYFVKYLADSYTNGKVIM
HHHHHHHHHCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
FGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLPLEWINKWKHYSSELLPKRWEDRLNDY
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHCCC
TYVPRTKEISEKNKKLALHIASWYESTRQ
EECCCCHHHHCCCCEEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA