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The map label for this gene is ackA

Identifier: 15927288

GI number: 15927288

Start: 1751880

End: 1753082

Strand: Reverse

Name: ackA

Synonym: SA1533

Alternate gene names: 15927288

Gene position: 1753082-1751880 (Counterclockwise)

Preceding gene: 15927289

Following gene: 15927286

Centisome position: 62.28

GC content: 35.0

Gene sequence:

>1203_bases
ATGTCAAAATTAATCTTGGCTATCAATGCTGGTAGTTCATCATTAAAATTTCAATTAATTAGAATGCCTGAAGAGGAATT
AGTAACAAAAGGTTTAATAGAAAGAATCGGATTGAAGGATTCAATTTTTACAATTGAAGTCAACGGGGAAAAAGTTAAAA
CAGTACAAGATATCAAGGATCACGTTGAGGCAGTTGATATCATGTTGGATGCTTTTAAAGCGCATAATATTATTAATGAT
ATTAACGATATCGATGGAACAGGTCACCGTGTTGTACATGGTGGTGAAAAATTCCCTGAATCAGTAGCTATTACTGATGA
GGTTGAAAAGGAAATTGAAGAATTAAGCGAATTAGCACCGCTTCACAACCCAGCTAACTTGATGGGTATTCGTGCTTTCC
GTAAGTTATTACCAAATATCCCTCATGTGGCAATTTTTGATACAGCATTCCATCAAACAATGCCTGAAAAAGCATATCTA
TATAGCTTGCCATATCATTATTATAAAGATTATGGCATTCGTAAGTATGGTTTCCATGGTACAAGCCATAAATTTGTATC
ACAAAGAGCGGCAGAAATGTTAGATAAGCCAATTGAAGATTTACGTATTATTTCATGTCACATTGGTAATGGAGCATCAA
TTGCAGCTATCGATGGCGGTAAATCTATTGATACATCAATGGGCTTCACACCACTTGCTGGTGTAACAATGGGTACTCGT
TCTGGTAATATTGACCCTGCTTTAATTCCATTTATTATGGAAAAAACAGGTAAAACTGCTGAACAAGTATTGGAAATCTT
AAACAAAGAATCAGGTTTATTAGGATTATCAGGTACATCTAGTGATTTACGTGACTTATCAGAAGAAGCTGAATCAGGTA
AAGCACGTTCACAAATGGCTTTAGATGTATTTGCTTCTAAAATTCACAAATATATTGGATCATATGCTGCGAGAATGCAT
GGTGTTGATGTTATCGTATTTACAGCAGGTATCGGTGAAAACTCAGTAGAAATTCGTGCGAAAGTTCTTGAAGGCTTAGA
ATTTATGGGTGTTTACTGGGATCCTAAGAAAAATGAAAACTTACTACGTGGTAAAGAAGGATTTATTAACTATCCTCATT
CACCAGTTAAAGTTGTCGTTATTCCAACAGATGAAGAAAGTATGATTGCCCGTGATGTTATGACATTCGGTGGTTTAAAA
TAA

Upstream 100 bases:

>100_bases
TCCTAAAAAATAATCTGTAATAGTATAGTCATAAAACTGTATGAATGATAAAATGAGAAATGAAATAGTATAAAAAGCAA
ACGATGGAGGATCATTACTT

Downstream 100 bases:

>100_bases
TTTTTAAATAAATATTAAGCGTCTATCTCCGCTACAATTATATGTAGGAGGTAGACGCTTTTTGTATTGTTTGAAAATTA
ACTAGTGTAATGTCTCTTTT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIIND
INDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYL
YSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTR
SGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMH
GVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK

Sequences:

>Translated_400_residues
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIIND
INDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYL
YSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTR
SGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMH
GVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
>Mature_399_residues
SKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDI
NDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLY
SLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRS
GNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHG
VDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=395, Percent_Identity=45.5696202531646, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=41.6666666666667, Blast_Score=317, Evalue=1e-87,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44057; Mature: 43926

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKD
CCEEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHH
HVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHCC
LHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHG
CCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCEEEECCHHHHHCCCCEEECCCC
TSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTR
CCHHHHHHHHHHHHHCCHHHEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEECCC
SGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMA
CCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHH
LDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNEN
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCHHEEEEEECCCCCCC
LLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
CCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKD
CEEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHH
HVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHCC
LHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHG
CCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCEEEECCHHHHHCCCCEEECCCC
TSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTR
CCHHHHHHHHHHHHHCCHHHEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEECCC
SGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMA
CCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHH
LDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNEN
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCHHEEEEEECCCCCCC
LLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
CCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA