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The map label for this gene is gpsA

Identifier: 15927055

GI number: 15927055

Start: 1511153

End: 1512151

Strand: Reverse

Name: gpsA

Synonym: SA1306

Alternate gene names: 15927055

Gene position: 1512151-1511153 (Counterclockwise)

Preceding gene: 15927056

Following gene: 15927054

Centisome position: 53.72

GC content: 34.33

Gene sequence:

>999_bases
ATGACTAAAATTACCGTTTTTGGTATGGGAAGTTTTGGGACAGCCCTTGCCAATGTTCTTGCAGAAAATGGACATGATGT
TTTGATGTGGGGTAAAAATCAAGATGCTGTTGATGAATTAAATACATGTCATACAAATAAAAAGTATTTAAAATACGCGA
AATTAGATGTTAACATCATCGCTACTTCAGATATGACCAAAGCAATTCAATTTGCAGATATTTACTTAATGGCTTTACCT
ACTAAAGCAATGCGAGAAGTTGCTACTCAAATTAATGATAAGCTGACCTCTAAAAAGACTTTTATACATGTTGCTAAAGG
TATTGAAAATGGGACGTTTAAACGTGTGTCAGAAATGATTGAAGATTCTATTTCACCCGAATATAATGCAGGTATTGGCG
TGTTGTCAGGGCCAAGTCATGCGGAAGAAGTTGTAGTCAAGCAACCAACTACAGTTGCTGCATCATCAAAAGATAAAAGT
GTAAGTAAATTAACGCAAGATTTATTTATGAATGATTATTTGCGTGTGTACACGAATGATGACTTGATTGGTGTTGAACT
TGGTGGTGCATTGAAAAATATCATCGCAGTAGCAAGTGGTATCGTAGCTGGAATTGGCTACGGTGATAATGCAAAAGCTG
CGTTAATGACTCGTGGTTTAGCGGAAATTAGTAGATTAGGTGAAAAGTTAGGTGCCGATCCTATGACATTTCTAGGTTTA
GGTGGTATCGGTGACTTAATCGTTACTTGCATATCAACACATTCTCGAAATTTCACATTAGGATATAAACTTGGACAAGG
TGAATCAATGGATCAAGCATTATCTGAAATGAATATGGTTGTTGAAGGTATTTATACAACTAAATCAGTTTATCATTTAG
CTAAAGAAAAAAATGTGGATATGCCAATTACAAATGCATTATATAGAGTATTATTTGAAAATATCTCAGTAAAAGAATGC
GTAAAAGATTTAATGGAGCGCGATAAAAAATCTGAATAA

Upstream 100 bases:

>100_bases
AAACGCTATTTAGAGAATCAAATCCGTGCCGCTTTTGGTTTTGAAGGTACACCAATTCATATTATAGCTCGAAAGAGAAA
TTAACGATTGGGGGATAACA

Downstream 100 bases:

>100_bases
AATGTGTATTATTACACATATACGGCTAATAATTACGTAAAATGAATAGAAATGGCTTAAATTCAACGTTTTTGCCACAT
AAATGATTGCGATTTATGTA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCHTNKKYLKYAKLDVNIIATSDMTKAIQFADIYLMALP
TKAMREVATQINDKLTSKKTFIHVAKGIENGTFKRVSEMIEDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKS
VSKLTQDLFMNDYLRVYTNDDLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTRGLAEISRLGEKLGADPMTFLGL
GGIGDLIVTCISTHSRNFTLGYKLGQGESMDQALSEMNMVVEGIYTTKSVYHLAKEKNVDMPITNALYRVLFENISVKEC
VKDLMERDKKSE

Sequences:

>Translated_332_residues
MTKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCHTNKKYLKYAKLDVNIIATSDMTKAIQFADIYLMALP
TKAMREVATQINDKLTSKKTFIHVAKGIENGTFKRVSEMIEDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKS
VSKLTQDLFMNDYLRVYTNDDLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTRGLAEISRLGEKLGADPMTFLGL
GGIGDLIVTCISTHSRNFTLGYKLGQGESMDQALSEMNMVVEGIYTTKSVYHLAKEKNVDMPITNALYRVLFENISVKEC
VKDLMERDKKSE
>Mature_331_residues
TKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCHTNKKYLKYAKLDVNIIATSDMTKAIQFADIYLMALPT
KAMREVATQINDKLTSKKTFIHVAKGIENGTFKRVSEMIEDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKSV
SKLTQDLFMNDYLRVYTNDDLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTRGLAEISRLGEKLGADPMTFLGLG
GIGDLIVTCISTHSRNFTLGYKLGQGESMDQALSEMNMVVEGIYTTKSVYHLAKEKNVDMPITNALYRVLFENISVKECV
KDLMERDKKSE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=343, Percent_Identity=28.8629737609329, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI24307999, Length=336, Percent_Identity=29.7619047619048, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1790037, Length=330, Percent_Identity=38.4848484848485, Blast_Score=242, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI32564399, Length=331, Percent_Identity=28.3987915407855, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI193210136, Length=340, Percent_Identity=27.9411764705882, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32564403, Length=340, Percent_Identity=27.9411764705882, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17507425, Length=276, Percent_Identity=28.2608695652174, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI193210134, Length=328, Percent_Identity=26.5243902439024, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324513, Length=360, Percent_Identity=30.2777777777778, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6320181, Length=356, Percent_Identity=29.7752808988764, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136200, Length=327, Percent_Identity=27.82874617737, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136204, Length=327, Percent_Identity=27.82874617737, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136202, Length=327, Percent_Identity=27.82874617737, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI22026922, Length=349, Percent_Identity=24.6418338108883, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45551945, Length=239, Percent_Identity=29.2887029288703, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362270, Length=239, Percent_Identity=29.2887029288703, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648969, Length=191, Percent_Identity=31.413612565445, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_STAA1 (A7X2I0)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442052.1
- ProteinModelPortal:   A7X2I0
- SMR:   A7X2I0
- STRING:   A7X2I0
- EnsemblBacteria:   EBSTAT00000004733
- GeneID:   5559066
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1462
- eggNOG:   COG0240
- GeneTree:   EBGT00050000024208
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- BioCyc:   SAUR418127:SAHV_1462-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36098; Mature: 35967

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 192-192 BINDING 106-106 BINDING 106-106 BINDING 141-141 BINDING 256-256 BINDING 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCHTNKKYLKYAKLDVNII
CCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHEEEEEEEEEE
ATSDMTKAIQFADIYLMALPTKAMREVATQINDKLTSKKTFIHVAKGIENGTFKRVSEMI
ECCCHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKSVSKLTQDLFMNDYLRVYTND
HHCCCCCCCCCCEECCCCCCHHHEEEECCCEEECCCCCHHHHHHHHHHHHCCEEEEEECC
DLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTRGLAEISRLGEKLGADPMTFLGL
CEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEC
GGIGDLIVTCISTHSRNFTLGYKLGQGESMDQALSEMNMVVEGIYTTKSVYHLAKEKNVD
CCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MPITNALYRVLFENISVKECVKDLMERDKKSE
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCHTNKKYLKYAKLDVNII
CEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHEEEEEEEEEE
ATSDMTKAIQFADIYLMALPTKAMREVATQINDKLTSKKTFIHVAKGIENGTFKRVSEMI
ECCCHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKSVSKLTQDLFMNDYLRVYTND
HHCCCCCCCCCCEECCCCCCHHHEEEECCCEEECCCCCHHHHHHHHHHHHCCEEEEEECC
DLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTRGLAEISRLGEKLGADPMTFLGL
CEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEC
GGIGDLIVTCISTHSRNFTLGYKLGQGESMDQALSEMNMVVEGIYTTKSVYHLAKEKNVD
CCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MPITNALYRVLFENISVKECVKDLMERDKKSE
CCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA