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The map label for this gene is argC

Identifier: 15925888

GI number: 15925888

Start: 208136

End: 209167

Strand: Reverse

Name: argC

Synonym: SA0178

Alternate gene names: 15925888

Gene position: 209167-208136 (Counterclockwise)

Preceding gene: 15925889

Following gene: 15925887

Centisome position: 7.43

GC content: 34.98

Gene sequence:

>1032_bases
ATGATTAAAGTAGGTATCGTTGGCGGTAGCGGTTATGGCGCAATTGAATTAATTCGATTGTTACAAACACATCCTCATGT
AACGATTGCACACATCTACTCACATTCAAAAGTAGATGAACCGTTGAAATTAACATTTCCACATTTACAACATATTATGC
AACATTTCGAAGCACTTACAGTGGACAATAATGACTGTGATGTAATTTTCTTTGCGACACCAGCACCCGTAAGTAAAACA
TGTATCCCTCCCTTAGTAGAAAAAGGTATTCATGTTATCGATTTATCTGGCGCATTTAGAATTAAGAATCGTGAAATATA
TGAAGCATATTACAAAGAAACTGCTGCAGCACAAGATGATTTGAATCATGCTATTTACAGCATTTCAGAATGGCAATCGT
TTGATAACAATGGAACGAAGCTCATTTCTAATCCTGGCTGTTTCCCTACAGCAACATTATTAGCATTACATCCACTTATT
AGCGAAAAAATAGTAGATTTGTCATCTATTATTATTGATGCTAAGACCGGCGTGTCAGGTGCTGGTCGTTCATTATCACA
ACGTGTTCATTTTTCAGAAATGAATGAAAATCTAAGTGCTTATGCAATCGGAAACCATAAACACAAACCGGAAATCGAGC
AATATTTATCTATCATTGCGGGTCAAGATGTATCAGTCATATTTACACCACATCTCGTACCAATGACACGAGGTATTTTA
TCAACAATTTATGTCAAATTTTCATCTGAATATACGACTGAATCATTACATAAATTAATGACCTCTTATTATGCTAATCA
GCCATTTGTCAGAATTAGAGATATTGGGACTTTTCCAACCACAAAAGAAGTACTCGGTAGTAACTACTGCGATATCGGTA
TCTATGTAGATGAAACAACACAAACAGCAATTTTAGTATCAGTGATTGATAACCTTGTCAAAGGCGCAAGTGGTCAAGCC
ATTCAAAATTTAAATATATTATATGATTTTGAAGTAACGACTGGCCTAAATCAATCACCAGTTTATCCATAA

Upstream 100 bases:

>100_bases
TTATTGATAAAGAGGAAATCCATCAAATTGTTGCAGCTTTTCAAGACGTTTTTAAAAATTAACAATTAATCATTTATATA
TGACATAGGAGGGATTCATG

Downstream 100 bases:

>100_bases
GGGGTGTTAGAATGAAACATCAAGAAACGACATCACAACAATATAACTTTTCAATTATTAAACATGGCGATATCAGTACA
CCTCAAGGCTTCACGGCTGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSKT
CIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLI
SEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGIL
STIYVKFSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQA
IQNLNILYDFEVTTGLNQSPVYP

Sequences:

>Translated_343_residues
MIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSKT
CIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLI
SEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGIL
STIYVKFSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQA
IQNLNILYDFEVTTGLNQSPVYP
>Mature_343_residues
MIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSKT
CIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLI
SEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGIL
STIYVKFSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQA
IQNLNILYDFEVTTGLNQSPVYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=37.7906976744186, Blast_Score=204, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=353, Percent_Identity=24.929178470255, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_STAA1 (A7WXH5)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001440773.1
- ProteinModelPortal:   A7WXH5
- SMR:   A7WXH5
- STRING:   A7WXH5
- EnsemblBacteria:   EBSTAT00000003875
- GeneID:   5560176
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0183
- eggNOG:   COG0002
- GeneTree:   EBGT00050000025670
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   SAUR418127:SAHV_0183-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37925; Mature: 37925

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALT
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECHHHHHHHHHHHEEE
VDNNDCDVIFFATPAPVSKTCIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDD
ECCCCCCEEEEECCCCCCCCCCCHHHHCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHH
LNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLISEKIVDLSSIIIDAKTGVSG
HHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
AGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGIL
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
STIYVKFSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETT
HHEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCEEEEEEEECCC
QTAILVSVIDNLVKGASGQAIQNLNILYDFEVTTGLNQSPVYP
CHHHHHHHHHHHHCCCCCCEEECCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALT
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECHHHHHHHHHHHEEE
VDNNDCDVIFFATPAPVSKTCIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDD
ECCCCCCEEEEECCCCCCCCCCCHHHHCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHH
LNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLISEKIVDLSSIIIDAKTGVSG
HHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
AGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGIL
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
STIYVKFSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETT
HHEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCEEEEEEEECCC
QTAILVSVIDNLVKGASGQAIQNLNILYDFEVTTGLNQSPVYP
CHHHHHHHHHHHHCCCCCCEEECCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA