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The map label for this gene is dapE [H]

Identifier: 15924996

GI number: 15924996

Start: 2129758

End: 2130960

Strand: Direct

Name: dapE [H]

Synonym: SAV2006

Alternate gene names: 15924996

Gene position: 2129758-2130960 (Clockwise)

Preceding gene: 15924993

Following gene: 15924997

Centisome position: 73.99

GC content: 34.33

Gene sequence:

>1203_bases
ATGACAACTTTTAGTGAAAAAGAAAAAATTCAATTACTAGCAGATATTGTTGAACTACAAACTGAAAATAATAATGAAAT
AGACGTTTGTAATTATTTAAAAGATTTATTCGACAAGTACGATATTAAATCTGAAATTTTGAAAGTTAATGAACACCGCG
CCAATATCGTTGCAGAAATCGGTAACGGCTCACCTATACTCGCATTGAGTGGTCATATGGATGTTGTTGATGCAGGAAAT
CAAGATAATTGGACTTATCCCCCTTTTCAACTCACAGAAAAAGCTGGCAAATTATACGGTCGAGGCACAACGGATATGAA
AGGCGGTCTGATGGCTTTGGTCATCACACTCATTGAATTAAAAGAACAAAATCAATTGCCTCAAGGAACGATAAGATTAC
TAGCTACTGCTGGCGAAGAGAAAGAACAAGAAGGTGCCAAATTATTGGCTGATAAAGGCTATTTAGACGATGTAGATGGC
TTAATTATTGCTGAACCAACTGGATCTGGAATTTATTATGCACATAAAGGGTCTATGTCATGTAAAGTAACTGCAACTGG
CAAAGCTGTCCATAGCTCAGTTCCATTTATTGGTGACAATGCAATTGATACACTGCTTGAATTTTATAATCAATTTAAAG
AAAAATATTCAGAGCTTAAAAAACATGATACTAAACATGAATTAGATGTTGCACCCATGTTCAAATCATTGATAGGAAAA
GAAATTTCTGAAGAGGATGCAAATTATGCATCTGGTCTTACAGCTGTATGTTCGATTATAAATGGCGGCAAACAATTTAA
CTCTGTACCAGATGAAGCTTCACTTGAATTTAACGTAAGACCAGTTCCTGAGTATGATAACGACTTTATAGAATCGTTTT
TCCAAAATATCATTAATGATGTGGATAGCAATAAGCTTTCACTCGATATTCCAAGCAATCACCGACCTGTAACAAGCGAT
AAAAATAGCAAATTAATTACTACGATTAAAGATGTAGCTTCTAGTTATGTAGAACAAGACGAAATATTTGTTTCAGCGCT
TGTAGGTGCAACAGATGCCTCTAGTTTCTTAGGAGATAATAAGGACAATGTTGATTTAGCCATTTTTGGACCAGGTAATC
CATTAATGGCACATCAAATCGATGAATATTGTTTGACTGTAAATATTCAAATATCAACAAGCACATTTTCATTGATTAAG
TGA

Upstream 100 bases:

>100_bases
AAATCAAATAACACGCTACTTTCTGCATTTTAAATTATGTTTAAGAATAAAAATTATGTTTATATAAATATATATACTAC
TTTGAAAAGGTGTGAGCTTA

Downstream 100 bases:

>100_bases
TGTAAAACTGAAATTATGGTGGTGATTTGTCATACATATATTGCATTGTCTATTGAAATTGGGAATCCAATTTCTCTTTG
TTGAGGCCCCCACCCCAACT

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGN
QDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDG
LIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSD
KNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYCLTVNIQISTSTFSLIK

Sequences:

>Translated_400_residues
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGN
QDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDG
LIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSD
KNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYCLTVNIQISTSTFSLIK
>Mature_399_residues
TTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQ
DNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGL
IIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKE
ISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDK
NSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYCLTVNIQISTSTFSLIK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=378, Percent_Identity=27.2486772486773, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788816, Length=355, Percent_Identity=22.8169014084507, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789236, Length=215, Percent_Identity=26.5116279069767, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 43996; Mature: 43865

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEI
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEC
GNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIEL
CCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
KEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMS
HHHCCCCHHHEEEEEECCCHHHHHHHHEECCCCCCCCCCCEEEECCCCCCEEEEECCCCE
CKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCC
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIIND
HHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
VDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDN
CCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
KDNVDLAIFGPGNPLMAHQIDEYCLTVNIQISTSTFSLIK
CCCEEEEEECCCCCCHHHCCCCEEEEEEEEEECCHHHHCC
>Mature Secondary Structure 
TTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEI
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEC
GNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIEL
CCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
KEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMS
HHHCCCCHHHEEEEEECCCHHHHHHHHEECCCCCCCCCCCEEEECCCCCCEEEEECCCCE
CKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGK
EEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCC
EISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIIND
HHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
VDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDN
CCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
KDNVDLAIFGPGNPLMAHQIDEYCLTVNIQISTSTFSLIK
CCCEEEEEECCCCCCHHHCCCCEEEEEEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]