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The map label for this gene is traP

Identifier: 15924825

GI number: 15924825

Start: 1965370

End: 1965873

Strand: Direct

Name: traP

Synonym: SAV1835

Alternate gene names: 15924825

Gene position: 1965370-1965873 (Clockwise)

Preceding gene: 15924813

Following gene: 15924828

Centisome position: 68.28

GC content: 31.35

Gene sequence:

>504_bases
ATGAAGAAACTATATACATCTTATGGCACTTATGGATTTTTACATCAAATAAAAATCAATAACCCGACCCATCAACTATT
CCAATTTTCAGCATCAGATACTTCAGTTATTTTTGAAGAAACTGATGGTGAGACTGTTTTAAAATCACCTTCAATATATG
AAGTTATTAAAGAAATTGGTGAATTCAGTGAACATCATTTCTATTGTGCAATCTTCATTCCTTCAACAGAAGATCATGCA
TATCAACTTGAAAAGAAACTGATTAGTGTAGACGATAATTTCAGAAACTTTGGTGGCTTTAAAAGCTATCGTTTGTTAAG
ACCTGCTAAAGGTACAACATATAAAATTTATTTCGGATTTGCTGATCGACATGCATACGAAGACTTTAAGCAATCTGATG
CCTTTAATGACCATTTTTCAAAAGACGCATTAAGTCATTACTTTGGTTCAAGCGGACAACATTCAAGTTATTTTGAAAGA
TATCTATACCCAATAAAAGAATAG

Upstream 100 bases:

>100_bases
TCTCGCAAGATTCATTATAGTAATTTTAATCAATTATTAATAGTGGTAATGACTAGTTTATCATCGTATAATAAATAAAA
ACATAAGGGGGACCTTTCAT

Downstream 100 bases:

>100_bases
ACTCGAAGAAAACTTCCATTGGTTATGCTGTTAACGTATAGATGCTAATGTAATCTGAACGCCGTATCATTTGGCGTTCA
ACATTACATGCACCTTTACA

Product: signal transduction protein

Products: NA

Alternate protein names: Target of RNAIII-activating protein

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHA
YQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFER
YLYPIKE

Sequences:

>Translated_167_residues
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHA
YQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFER
YLYPIKE
>Mature_167_residues
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHA
YQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFER
YLYPIKE

Specific function: Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the exp

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane. Note=Membrane-associated

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRAP family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRAP_STAA3 (Q2FFR1)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494467.1
- STRING:   Q2FFR1
- EnsemblBacteria:   EBSTAT00000037976
- GeneID:   3912928
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_1784
- eggNOG:   NOG145299
- GeneTree:   EBGT00050000025290
- HOGENOM:   HBG693144
- OMA:   TAYEDFK
- ProtClustDB:   CLSK885591
- GO:   GO:0005737
- GO:   GO:0016020
- GO:   GO:0009405
- InterPro:   IPR007138
- InterPro:   IPR011008

Pfam domain/function: PF03992 ABM; SSF54909 Dimer_A_B_barrel

EC number: NA

Molecular weight: Translated: 19548; Mature: 19548

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIG
CCCEECCCCCCEEEEEEEECCCHHHHEEECCCCCEEEEECCCCCEEECCCCHHHHHHHHH
EFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGF
HHCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCEEEEEEEC
ADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFERYLYPIKE
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIG
CCCEECCCCCCEEEEEEEECCCHHHHEEECCCCCEEEEECCCCCEEECCCCHHHHHHHHH
EFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGF
HHCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCEEEEEEEC
ADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFERYLYPIKE
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA