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The map label for this gene is gnd [H]

Identifier: 15924501

GI number: 15924501

Start: 1626974

End: 1628380

Strand: Reverse

Name: gnd [H]

Synonym: SAV1511

Alternate gene names: 15924501

Gene position: 1628380-1626974 (Counterclockwise)

Preceding gene: 15924502

Following gene: 15924500

Centisome position: 56.57

GC content: 33.83

Gene sequence:

>1407_bases
ATGACACAACAAATTGGAGTTATTGGTTTAGCCGTTATGGGTAAAAACCTAGCTTGGAATATTGAATCACACGGATATAG
TGTATCTGTATTTAACCGCTCAAGTGAAAAAACTGATTTAATGGTTGAAGAATCAAAAGGGAAAAATATTCATCCAACGT
ATTCATTGGAAGAATTTGTTAATTCTTTAGAAAAACCACGTAAAATTTTATTAATGGTTCAAGCAGGTAAAGCTACGGAT
GCAACAATTGATAGTTTGTTACCTTTATTAGATGATGGAGATATTTTAATTGATGGTGGTAATACAAACTATCAAGATAC
TATCAGACGTAATAAAGCATTAGCACAAAGTGCAATCAACTTTATTGGTATGGGCGTTTCTGGTGGTGAAATTGGAGCGT
TAACTGGTCCGTCATTAATGCCGGGTGGACAAGAAGAAGCTTATAACAAAGTTGCAGATATTCTTGATGCAATTGCTGCT
AAGGCAAAAGACGGTGCTTCATGTGTTACTTATATTGGACCAAATGGTGCTGGACACTATGTGAAAATGGTACATAATGG
TATTGAATATGCTGACATGCAATTAATTGCAGAAAGTTATGCTATGATGAAAGAATTATTAGGTATGTCTCATGAAGACA
TTGCTCAAACGTTCAAAGACTGGAATGCTGGTGAATTAGAAAGTTATTTAATTGAAATCACTGGTGATATTTTCATGAAA
TTAGATGAAAATAAAGAAGCATTAGTTGAAAAAATTCTTGATACTGCAGGTCAAAAAGGTACAGGAAAATGGACTTCAAT
TAATGCATTAGAATTAGGTATTCCATTAACAATCATTACTGAATCTGTATTTGCACGTTTTATCTCTTCAATCAAAGAAG
AGCGCGTAAATGCTTCTAAAGAATTAAATGGTCCAAAAGCATCATTTGATGGTGACAAGAAAGACTTTTTAGAAAAAATT
CGTAAAGCATTATATATGAGTAAAATTTGTTCTTATGCACAAGGTTTCGCGCAAATGCGTAAAGCAAGTGAAGATAATGA
ATGGAATTTAAAACTTGGTGATTTAGCTATGATTTGGAGAGAAGGTTGCATTATACGTGCACAATTCTTACAAAAGATCA
AAGATGCTTACGATAATAATCCAGGATTACAAAACTTATTGCTAGATCCTTACTTTAAAAACATCGTTACTGAATATCAA
GATGCGTTACGTGATGTTGTCGCAACTGGTGTTCAAAATGGTGTACCAACACCTGGTTTCTCATCAAGTATTAATTACTA
TGATAGTTACCGTGCAGCTGATTTACCTGCAAACTTAATTCAAGCACAACGTGACTACTTCGGTGCTCACACGTACGAAA
GAAAAGATAAAGAAGGCGTATTCCATACACAATGGATTGAAGAATAA

Upstream 100 bases:

>100_bases
ATAATCAAAATAGTTGCGCGACAATCGAAATGATTTAGTGTAGTGTATGTCTATTTTGTGATACAATACTAATGAAAAAT
CAACAAGTGAGGTAAGTAAT

Downstream 100 bases:

>100_bases
TATTGACCATTGAGCCTGAGACCTTATGAATTTAGGTAATGTTAAAGAGACAATTTCTATTATTTATTTGATAGAAATTG
TCTCTTTCCTTATGTATTTA

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTQQIGVIGLAVMGKNLAWNIESHGYSVSVFNRSSEKTDLMVEESKGKNIHPTYSLEEFVNSLEKPRKILLMVQAGKATD
ATIDSLLPLLDDGDILIDGGNTNYQDTIRRNKALAQSAINFIGMGVSGGEIGALTGPSLMPGGQEEAYNKVADILDAIAA
KAKDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYAMMKELLGMSHEDIAQTFKDWNAGELESYLIEITGDIFMK
LDENKEALVEKILDTAGQKGTGKWTSINALELGIPLTIITESVFARFISSIKEERVNASKELNGPKASFDGDKKDFLEKI
RKALYMSKICSYAQGFAQMRKASEDNEWNLKLGDLAMIWREGCIIRAQFLQKIKDAYDNNPGLQNLLLDPYFKNIVTEYQ
DALRDVVATGVQNGVPTPGFSSSINYYDSYRAADLPANLIQAQRDYFGAHTYERKDKEGVFHTQWIEE

Sequences:

>Translated_468_residues
MTQQIGVIGLAVMGKNLAWNIESHGYSVSVFNRSSEKTDLMVEESKGKNIHPTYSLEEFVNSLEKPRKILLMVQAGKATD
ATIDSLLPLLDDGDILIDGGNTNYQDTIRRNKALAQSAINFIGMGVSGGEIGALTGPSLMPGGQEEAYNKVADILDAIAA
KAKDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYAMMKELLGMSHEDIAQTFKDWNAGELESYLIEITGDIFMK
LDENKEALVEKILDTAGQKGTGKWTSINALELGIPLTIITESVFARFISSIKEERVNASKELNGPKASFDGDKKDFLEKI
RKALYMSKICSYAQGFAQMRKASEDNEWNLKLGDLAMIWREGCIIRAQFLQKIKDAYDNNPGLQNLLLDPYFKNIVTEYQ
DALRDVVATGVQNGVPTPGFSSSINYYDSYRAADLPANLIQAQRDYFGAHTYERKDKEGVFHTQWIEE
>Mature_467_residues
TQQIGVIGLAVMGKNLAWNIESHGYSVSVFNRSSEKTDLMVEESKGKNIHPTYSLEEFVNSLEKPRKILLMVQAGKATDA
TIDSLLPLLDDGDILIDGGNTNYQDTIRRNKALAQSAINFIGMGVSGGEIGALTGPSLMPGGQEEAYNKVADILDAIAAK
AKDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYAMMKELLGMSHEDIAQTFKDWNAGELESYLIEITGDIFMKL
DENKEALVEKILDTAGQKGTGKWTSINALELGIPLTIITESVFARFISSIKEERVNASKELNGPKASFDGDKKDFLEKIR
KALYMSKICSYAQGFAQMRKASEDNEWNLKLGDLAMIWREGCIIRAQFLQKIKDAYDNNPGLQNLLLDPYFKNIVTEYQD
ALRDVVATGVQNGVPTPGFSSSINYYDSYRAADLPANLIQAQRDYFGAHTYERKDKEGVFHTQWIEE

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=464, Percent_Identity=56.8965517241379, Blast_Score=526, Evalue=1e-149,
Organism=Escherichia coli, GI1788341, Length=465, Percent_Identity=66.8817204301075, Blast_Score=655, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17542558, Length=466, Percent_Identity=51.2875536480687, Blast_Score=496, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6321695, Length=452, Percent_Identity=51.3274336283186, Blast_Score=478, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6321977, Length=456, Percent_Identity=51.3157894736842, Blast_Score=470, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24639279, Length=464, Percent_Identity=52.3706896551724, Blast_Score=468, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 51784; Mature: 51653

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQIGVIGLAVMGKNLAWNIESHGYSVSVFNRSSEKTDLMVEESKGKNIHPTYSLEEFV
CCCCCCEEEHEEECCCEEEEECCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHH
NSLEKPRKILLMVQAGKATDATIDSLLPLLDDGDILIDGGNTNYQDTIRRNKALAQSAIN
HHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
FIGMGVSGGEIGALTGPSLMPGGQEEAYNKVADILDAIAAKAKDGASCVTYIGPNGAGHY
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
VKMVHNGIEYADMQLIAESYAMMKELLGMSHEDIAQTFKDWNAGELESYLIEITGDIFMK
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHEECCEEEE
LDENKEALVEKILDTAGQKGTGKWTSINALELGIPLTIITESVFARFISSIKEERVNASK
ECCCHHHHHHHHHHHCCCCCCCCCEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHCHHH
ELNGPKASFDGDKKDFLEKIRKALYMSKICSYAQGFAQMRKASEDNEWNLKLGDLAMIWR
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
EGCIIRAQFLQKIKDAYDNNPGLQNLLLDPYFKNIVTEYQDALRDVVATGVQNGVPTPGF
CCCCHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SSSINYYDSYRAADLPANLIQAQRDYFGAHTYERKDKEGVFHTQWIEE
CCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
TQQIGVIGLAVMGKNLAWNIESHGYSVSVFNRSSEKTDLMVEESKGKNIHPTYSLEEFV
CCCCCEEEHEEECCCEEEEECCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHH
NSLEKPRKILLMVQAGKATDATIDSLLPLLDDGDILIDGGNTNYQDTIRRNKALAQSAIN
HHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
FIGMGVSGGEIGALTGPSLMPGGQEEAYNKVADILDAIAAKAKDGASCVTYIGPNGAGHY
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHH
VKMVHNGIEYADMQLIAESYAMMKELLGMSHEDIAQTFKDWNAGELESYLIEITGDIFMK
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHEECCEEEE
LDENKEALVEKILDTAGQKGTGKWTSINALELGIPLTIITESVFARFISSIKEERVNASK
ECCCHHHHHHHHHHHCCCCCCCCCEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHCHHH
ELNGPKASFDGDKKDFLEKIRKALYMSKICSYAQGFAQMRKASEDNEWNLKLGDLAMIWR
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
EGCIIRAQFLQKIKDAYDNNPGLQNLLLDPYFKNIVTEYQDALRDVVATGVQNGVPTPGF
CCCCHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SSSINYYDSYRAADLPANLIQAQRDYFGAHTYERKDKEGVFHTQWIEE
CCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA