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The map label for this gene is dgk [H]

Identifier: 15923547

GI number: 15923547

Start: 626274

End: 626891

Strand: Reverse

Name: dgk [H]

Synonym: SAV0557

Alternate gene names: 15923547

Gene position: 626891-626274 (Counterclockwise)

Preceding gene: 15923555

Following gene: 15923546

Centisome position: 21.78

GC content: 26.7

Gene sequence:

>618_bases
ATGAACAAACCTTTTATAGCAATTGAAGGTCCTATTGGCGTAGGTAAATCTTCACTTGCACACAAATTAAGTCAAACTTT
AGATTTTTATGAAGAAAAAGAAATCATCACAGAAAATCCATTTTTATCAGACTTTTATGAAGATATCTCTAAATGGAGTT
TTCAAACTGAAATGTTCTTTTTATGCAATAGATATAAGCAATTTCAAGATGTAACACAACTAAATCAAGGTGTAGTTAGT
GATTATCATATACATAAAAATAAGATATTTGCTAAAAATACTTTGAGTCCTGTTGAATTTCAGAAATTCAGTAAAATTTA
TGATATTTTAACTGAAGATATGATTATGCCGAATATGATTATCTTTTTAGATGCAGACCTTGATGTGTTAAAATCTAGAA
TTGCTAAACGTAACCGTAGTTTTGAGCATCAAATAGAAGATGAATATCTGTTAAAGTTAAAAAAAGATTATCGTGAGTAT
TATGAGTCCTTACAAAGTAATGGTTCAAATGTAGTTTTAATCGATACAACTTCTATTGATTTTCTTAAAAATGAACAAGA
TTACGAAGATATATTACATATTATATTACCTATGATAGGAGATATTACCAATGAATAA

Upstream 100 bases:

>100_bases
TCGCTAATGTCATAAAATATATATCATTTGTCATTTATGTCCAGATACCTCACTTATGGTACAATACTCAATGTCTATTT
TAACATTTGGAGATGTGAAT

Downstream 100 bases:

>100_bases
TTACGGTATTCCACAAAATGCCATTATAACCATTGCAGGTACAGTTGGTGTTGGAAAATCAACACTAACGCAAGCACTTG
CAGATAAATTAAACTTTAAA

Product: deoxypurine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDISKWSFQTEMFFLCNRYKQFQDVTQLNQGVVS
DYHIHKNKIFAKNTLSPVEFQKFSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREY
YESLQSNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE

Sequences:

>Translated_205_residues
MNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDISKWSFQTEMFFLCNRYKQFQDVTQLNQGVVS
DYHIHKNKIFAKNTLSPVEFQKFSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREY
YESLQSNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE
>Mature_205_residues
MNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDISKWSFQTEMFFLCNRYKQFQDVTQLNQGVVS
DYHIHKNKIFAKNTLSPVEFQKFSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREY
YESLQSNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24164; Mature: 24164

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDISKWSFQTEMFF
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LCNRYKQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSPVEFQKFSKIYDILTEDMIMPNMI
HHHHHHHHHHHHHHHHCCHHHHEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEE
IFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREYYESLQSNGSNVVLIDTTSID
EEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
FLKNEQDYEDILHIILPMIGDITNE
HHCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSDFYEDISKWSFQTEMFF
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LCNRYKQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSPVEFQKFSKIYDILTEDMIMPNMI
HHHHHHHHHHHHHHHHCCHHHHEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEE
IFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREYYESLQSNGSNVVLIDTTSID
EEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
FLKNEQDYEDILHIILPMIGDITNE
HHCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]