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The map label for this gene is dehH109 [H]

Identifier: 15922903

GI number: 15922903

Start: 2582575

End: 2583180

Strand: Direct

Name: dehH109 [H]

Synonym: ST2570

Alternate gene names: 15922903

Gene position: 2582575-2583180 (Clockwise)

Preceding gene: 15922902

Following gene: 15922904

Centisome position: 95.84

GC content: 33.17

Gene sequence:

>606_bases
GTGATCATTCTAGCATTTGATATCTTCGGAACAGTTCTTGATACATCTACGGTAATTCAAGAGTTTAGGAATAAGCAATT
AGAGTATACATGGTTACTTACAATAATGGGGAAATATGTGGAATTTGAGGAAATAACAAAGATTACTTTAAGATACATCT
TAAAGGTAAGAGGCGAAGAGAGCAAATTTGATGAGGAGTTAAATAAGTGGAAGAATCTTAAAGCTTATGAAGATACTAAA
TATTTAAAGGAAATATCTGAGATAGCCGAGGTCTACGCGTTATCTAACGGGTCTATAAATGAGGTTAAACAACATTTAGA
GCGCAATGGTTTGTTAAGATATTTTAAGGGCATATTTAGTGCAGAAAGTGTTAAAGAATATAAACCTTCACCTAAAGTAT
ACAAATATTTCCTAGACTCGATAGGAGCTAAAGAAGCATTCTTAGTTTCATCAAATGCATTTGACGTCATAGGAGCTAAA
AACGCGGGTATGAGGAGTATATTCGTAAATAGGAAGAATACAATAGTCGATCCTATAGGTGGCAAACCTGATGTTATAGT
AAATGACTTCAAAGAGTTATATGAATGGATTTTGCGATATAAGTGA

Upstream 100 bases:

>100_bases
ATGTAAAAAATTATAGTAATAACAAAAATTATTTAATAATATTAAAAGCTATAAAAACATTACAGATAGATATTTTAAGG
CTTAAATTAAAAGCTATATT

Downstream 100 bases:

>100_bases
TAAAGAGATGATTACAATTTACAAGATGCTATGAATTTTAATACCAAATTCTTAAACTTACTTAAGTTACGGACAATCTC
CTAACAAGGGTTTCTATGTA

Product: 2-haloalkanoic acid dehalogenase

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase H-109; Halocarboxylic acid halidohydrolase H-109; L-2-haloacid dehalogenase H-109 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIILAFDIFGTVLDTSTVIQEFRNKQLEYTWLLTIMGKYVEFEEITKITLRYILKVRGEESKFDEELNKWKNLKAYEDTK
YLKEISEIAEVYALSNGSINEVKQHLERNGLLRYFKGIFSAESVKEYKPSPKVYKYFLDSIGAKEAFLVSSNAFDVIGAK
NAGMRSIFVNRKNTIVDPIGGKPDVIVNDFKELYEWILRYK

Sequences:

>Translated_201_residues
MIILAFDIFGTVLDTSTVIQEFRNKQLEYTWLLTIMGKYVEFEEITKITLRYILKVRGEESKFDEELNKWKNLKAYEDTK
YLKEISEIAEVYALSNGSINEVKQHLERNGLLRYFKGIFSAESVKEYKPSPKVYKYFLDSIGAKEAFLVSSNAFDVIGAK
NAGMRSIFVNRKNTIVDPIGGKPDVIVNDFKELYEWILRYK
>Mature_201_residues
MIILAFDIFGTVLDTSTVIQEFRNKQLEYTWLLTIMGKYVEFEEITKITLRYILKVRGEESKFDEELNKWKNLKAYEDTK
YLKEISEIAEVYALSNGSINEVKQHLERNGLLRYFKGIFSAESVKEYKPSPKVYKYFLDSIGAKEAFLVSSNAFDVIGAK
NAGMRSIFVNRKNTIVDPIGGKPDVIVNDFKELYEWILRYK

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 23415; Mature: 23415

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILAFDIFGTVLDTSTVIQEFRNKQLEYTWLLTIMGKYVEFEEITKITLRYILKVRGEE
CEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SKFDEELNKWKNLKAYEDTKYLKEISEIAEVYALSNGSINEVKQHLERNGLLRYFKGIFS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHH
AESVKEYKPSPKVYKYFLDSIGAKEAFLVSSNAFDVIGAKNAGMRSIFVNRKNTIVDPIG
HHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHEEECCCCCEECCCC
GKPDVIVNDFKELYEWILRYK
CCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIILAFDIFGTVLDTSTVIQEFRNKQLEYTWLLTIMGKYVEFEEITKITLRYILKVRGEE
CEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SKFDEELNKWKNLKAYEDTKYLKEISEIAEVYALSNGSINEVKQHLERNGLLRYFKGIFS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHH
AESVKEYKPSPKVYKYFLDSIGAKEAFLVSSNAFDVIGAKNAGMRSIFVNRKNTIVDPIG
HHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHEEECCCCCEECCCC
GKPDVIVNDFKELYEWILRYK
CCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7764511 [H]