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The map label for this gene is appB [H]

Identifier: 15922869

GI number: 15922869

Start: 2543351

End: 2544352

Strand: Direct

Name: appB [H]

Synonym: ST2535

Alternate gene names: 15922869

Gene position: 2543351-2544352 (Clockwise)

Preceding gene: 15922867

Following gene: 15922870

Centisome position: 94.38

GC content: 34.13

Gene sequence:

>1002_bases
ATGAAAACATGGCTTATTCGACGTGTTATCATGTCGATAGTTACTATCCTAGCAACAATAATATTTACCTGGGCATTATT
AGAATTTTCACCTACAAGTCCAGCTAACTATATTCTTAGCCAAATTTCTCCATCAGCCTTAAGCTCCATTAGATCAGCCG
AGATATATACTAGTTTAGAGCAATATTTAGAAACTTTACGACCACATGGAAATCCAGTTATTCAAGCTTTAACTTACTTA
GGTAATTTTCTTCATGGAAATTTAGGAGTTAGTATAGTTTATGAGGTACCTGTAACTACATTAATAGCAAATGCCTTACC
ATGGACGCTTTTCGTGATTGTAACGTCAGTCATTATAAGCTTCTTTATTGGTATTAGGGCTGGAGAAATTATGGGATATA
AAAGAGGAACTAAAAAAGATTCTACTCTACTTATGACATTCATAACGATTAGGGCTATACCAATTTATATCTTAGGTACA
CTATTCTTATTCTTCTTAGGTTATGAACTTCATATATTTCCAAGCGGTGGTGCATATTCGGTTAATGTGACACCAGGGTT
TAATTTCCCATTTATTGAAAGTGTTCTTTATCACGCAACCCTACCAATCTTAACCTTAACGTTAATCAATTTAGCTGGTT
GGGCAATACATATGAGAGCTAATACAATTTATACATTAAGGGAGGACTATGTAGATTTTGCAGAAACTAGGGGTGTAATG
GATAAGATAATTGAATCAAAATATGTTGGAAGGAATTCAATACTACCCCTTTACACCAGTTTAATAATCACATTAGGTTT
CTCCTTTGGAGGTTCAGTCTTTTTAGAAGAAATCTTTAGTTATCCCGGCGTGGGATTACTTCTTTATAACTCAATAATGA
ATAACGATTACCCAGTAGAGATGGGTATTTTAGTTATAATAGTTTTAGCAGTCGTAATTGGAGTATTTTTGGCAGATCTA
ACATATTCCTTGCTGGATCCCAGAGTAAAAATGGGTGACTAG

Upstream 100 bases:

>100_bases
TATATAAACTTTTTCAAATGTTTAAGTACCGTAAAATTAGTGATAAACAATTGTTAGTTATATTAAATATTTATATAGTT
GGTGAATTAACACTATAATT

Downstream 100 bases:

>100_bases
ATTGCTTCTAAAAGTACAAGATCTATCAGTAGCTTACTTTATTCACAAGCAAGAAATAGTAGCATTAAAAGATGTTTCTT
TTGAAATAGAGAGGGGAGAA

Product: peptide transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKTWLIRRVIMSIVTILATIIFTWALLEFSPTSPANYILSQISPSALSSIRSAEIYTSLEQYLETLRPHGNPVIQALTYL
GNFLHGNLGVSIVYEVPVTTLIANALPWTLFVIVTSVIISFFIGIRAGEIMGYKRGTKKDSTLLMTFITIRAIPIYILGT
LFLFFLGYELHIFPSGGAYSVNVTPGFNFPFIESVLYHATLPILTLTLINLAGWAIHMRANTIYTLREDYVDFAETRGVM
DKIIESKYVGRNSILPLYTSLIITLGFSFGGSVFLEEIFSYPGVGLLLYNSIMNNDYPVEMGILVIIVLAVVIGVFLADL
TYSLLDPRVKMGD

Sequences:

>Translated_333_residues
MKTWLIRRVIMSIVTILATIIFTWALLEFSPTSPANYILSQISPSALSSIRSAEIYTSLEQYLETLRPHGNPVIQALTYL
GNFLHGNLGVSIVYEVPVTTLIANALPWTLFVIVTSVIISFFIGIRAGEIMGYKRGTKKDSTLLMTFITIRAIPIYILGT
LFLFFLGYELHIFPSGGAYSVNVTPGFNFPFIESVLYHATLPILTLTLINLAGWAIHMRANTIYTLREDYVDFAETRGVM
DKIIESKYVGRNSILPLYTSLIITLGFSFGGSVFLEEIFSYPGVGLLLYNSIMNNDYPVEMGILVIIVLAVVIGVFLADL
TYSLLDPRVKMGD
>Mature_333_residues
MKTWLIRRVIMSIVTILATIIFTWALLEFSPTSPANYILSQISPSALSSIRSAEIYTSLEQYLETLRPHGNPVIQALTYL
GNFLHGNLGVSIVYEVPVTTLIANALPWTLFVIVTSVIISFFIGIRAGEIMGYKRGTKKDSTLLMTFITIRAIPIYILGT
LFLFFLGYELHIFPSGGAYSVNVTPGFNFPFIESVLYHATLPILTLTLINLAGWAIHMRANTIYTLREDYVDFAETRGVM
DKIIESKYVGRNSILPLYTSLIITLGFSFGGSVFLEEIFSYPGVGLLLYNSIMNNDYPVEMGILVIIVLAVVIGVFLADL
TYSLLDPRVKMGD

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=330, Percent_Identity=26.969696969697, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789965, Length=347, Percent_Identity=25.0720461095101, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789888, Length=333, Percent_Identity=26.1261261261261, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788504, Length=360, Percent_Identity=26.1111111111111, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787497, Length=332, Percent_Identity=22.289156626506, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787761, Length=349, Percent_Identity=27.5071633237822, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=24.0601503759398, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37084; Mature: 37084

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTWLIRRVIMSIVTILATIIFTWALLEFSPTSPANYILSQISPSALSSIRSAEIYTSLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
QYLETLRPHGNPVIQALTYLGNFLHGNLGVSIVYEVPVTTLIANALPWTLFVIVTSVIIS
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
FFIGIRAGEIMGYKRGTKKDSTLLMTFITIRAIPIYILGTLFLFFLGYELHIFPSGGAYS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEE
VNVTPGFNFPFIESVLYHATLPILTLTLINLAGWAIHMRANTIYTLREDYVDFAETRGVM
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEHHHHHHHHHHHHHHH
DKIIESKYVGRNSILPLYTSLIITLGFSFGGSVFLEEIFSYPGVGLLLYNSIMNNDYPVE
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHH
MGILVIIVLAVVIGVFLADLTYSLLDPRVKMGD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTWLIRRVIMSIVTILATIIFTWALLEFSPTSPANYILSQISPSALSSIRSAEIYTSLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
QYLETLRPHGNPVIQALTYLGNFLHGNLGVSIVYEVPVTTLIANALPWTLFVIVTSVIIS
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
FFIGIRAGEIMGYKRGTKKDSTLLMTFITIRAIPIYILGTLFLFFLGYELHIFPSGGAYS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEE
VNVTPGFNFPFIESVLYHATLPILTLTLINLAGWAIHMRANTIYTLREDYVDFAETRGVM
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEHHHHHHHHHHHHHHH
DKIIESKYVGRNSILPLYTSLIITLGFSFGGSVFLEEIFSYPGVGLLLYNSIMNNDYPVE
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHH
MGILVIIVLAVVIGVFLADLTYSLLDPRVKMGD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]