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The map label for this gene is hoxN [H]

Identifier: 15922775

GI number: 15922775

Start: 2446102

End: 2447253

Strand: Direct

Name: hoxN [H]

Synonym: ST2443

Alternate gene names: 15922775

Gene position: 2446102-2447253 (Clockwise)

Preceding gene: 15922773

Following gene: 15922779

Centisome position: 90.77

GC content: 30.56

Gene sequence:

>1152_bases
ATGAAATATCTTTTGTTTGATATGGATAACTTATCCAAAAAGTTTATAATGTGGATAACTTATCCAAATATTATGGGTTC
TAAATCTTTAACAAAAATGGTATTTATGGGTTCATTTTTTATTATAAATATTATTTTGACTGTGATTTTTTATTTCATCT
TATTTAATTTACCAAAAGAGAATTTGCAAATACAAACTGATGATGGTGTACTAACTGGAACTTTCATAACTCTTGGTATT
TTAGCTTATACATTTGGATTAAGACATGCAGTAGACGCTGATCATCTTGCTGCGATCGATAATGTTACCAGAAAACTTCT
TCAAGAAGGAAGAAACCCAGTGTTTGTTGGCACATTCTTCTCGCTAGGTCATTCAACTGTAGTTATTCTTCTAAGCCTAA
TGTTAATCATAGCTTCAAGGTATATTATAAATAGTTTACCGAGCATTGAGAATGTAGGCAGTATTATAGGAACTTTAATA
AGTGGAGGGTTTTTGTATATAATAGCATTCTTAAACACTCTAGTCCTTTTAGAATTGTATGAGGTTTATAAAACCATTAG
AAAGGAGAAAAATCTTAATGAGAAGAAATTAAATGAACTCTTGTTAAAGAGGGGTTTCATGAATAGATTTTTCAATAAAT
TGTTTAAGATAGTTACTTCGGAATGGCAAATGTACGTTATAGGGTTTTTATTTGGTTTAGGTTTTGATACTGCAACTGAG
GTGGCTATATTAGCTATATCTGCGACAGTAGCTGGAGCTTTCTCCTCAATCCCAATAACTACTATACTAATTTTGCCAGG
ATTGTTTGCATTAGGTATGAGTTTAATAGATACGCTTGATGGATTGTTTATGAGATCTGCTTACGGTTGGGCTTTCAGAA
ATCCTTTGGGAAAAATCTGGTATAATTTGACAATGACCTTTATATCAATCTTGGTAGCTTATGGAATTGGTACAATAGAA
TTGTTTGGCTTAATAGTTAGTGAATTTAATCTTCATGGTCCATTTTGGGATCAAATAAATGCATTAAACAACGTATACTG
GGAATCAATAGGTTATTTCGTGATACTAACTTTTGCTATAACATGGATAATTTCTGCTTTAATATATAAAATGAAGATTA
AGCAGTTAAGTATGAAAAAAGTAGAATCTTAA

Upstream 100 bases:

>100_bases
ATAATCATAAAGGGAAAGTAATAATATAGTTAAGATTCGATGATGAAAAGCCCATATGCTGAATTAATGAAGAGATGCGG
GTACTCTGATCTTATATTTT

Downstream 100 bases:

>100_bases
ATAGCTTGATCATCTTTTTTAATATCTCTTATAATTCTAAATATTTGAATTACAATATCATCTGGTATTATTGGTGATAT
ATTAGGTTCACATTCTCCAA

Product: nickel transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKYLLFDMDNLSKKFIMWITYPNIMGSKSLTKMVFMGSFFIINIILTVIFYFILFNLPKENLQIQTDDGVLTGTFITLGI
LAYTFGLRHAVDADHLAAIDNVTRKLLQEGRNPVFVGTFFSLGHSTVVILLSLMLIIASRYIINSLPSIENVGSIIGTLI
SGGFLYIIAFLNTLVLLELYEVYKTIRKEKNLNEKKLNELLLKRGFMNRFFNKLFKIVTSEWQMYVIGFLFGLGFDTATE
VAILAISATVAGAFSSIPITTILILPGLFALGMSLIDTLDGLFMRSAYGWAFRNPLGKIWYNLTMTFISILVAYGIGTIE
LFGLIVSEFNLHGPFWDQINALNNVYWESIGYFVILTFAITWIISALIYKMKIKQLSMKKVES

Sequences:

>Translated_383_residues
MKYLLFDMDNLSKKFIMWITYPNIMGSKSLTKMVFMGSFFIINIILTVIFYFILFNLPKENLQIQTDDGVLTGTFITLGI
LAYTFGLRHAVDADHLAAIDNVTRKLLQEGRNPVFVGTFFSLGHSTVVILLSLMLIIASRYIINSLPSIENVGSIIGTLI
SGGFLYIIAFLNTLVLLELYEVYKTIRKEKNLNEKKLNELLLKRGFMNRFFNKLFKIVTSEWQMYVIGFLFGLGFDTATE
VAILAISATVAGAFSSIPITTILILPGLFALGMSLIDTLDGLFMRSAYGWAFRNPLGKIWYNLTMTFISILVAYGIGTIE
LFGLIVSEFNLHGPFWDQINALNNVYWESIGYFVILTFAITWIISALIYKMKIKQLSMKKVES
>Mature_383_residues
MKYLLFDMDNLSKKFIMWITYPNIMGSKSLTKMVFMGSFFIINIILTVIFYFILFNLPKENLQIQTDDGVLTGTFITLGI
LAYTFGLRHAVDADHLAAIDNVTRKLLQEGRNPVFVGTFFSLGHSTVVILLSLMLIIASRYIINSLPSIENVGSIIGTLI
SGGFLYIIAFLNTLVLLELYEVYKTIRKEKNLNEKKLNELLLKRGFMNRFFNKLFKIVTSEWQMYVIGFLFGLGFDTATE
VAILAISATVAGAFSSIPITTILILPGLFALGMSLIDTLDGLFMRSAYGWAFRNPLGKIWYNLTMTFISILVAYGIGTIE
LFGLIVSEFNLHGPFWDQINALNNVYWESIGYFVILTFAITWIISALIYKMKIKQLSMKKVES

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 43339; Mature: 43339

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLLFDMDNLSKKFIMWITYPNIMGSKSLTKMVFMGSFFIINIILTVIFYFILFNLPKE
CCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NLQIQTDDGVLTGTFITLGILAYTFGLRHAVDADHLAAIDNVTRKLLQEGRNPVFVGTFF
CCEEECCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEHHH
SLGHSTVVILLSLMLIIASRYIINSLPSIENVGSIIGTLISGGFLYIIAFLNTLVLLELY
HCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVYKTIRKEKNLNEKKLNELLLKRGFMNRFFNKLFKIVTSEWQMYVIGFLFGLGFDTATE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VAILAISATVAGAFSSIPITTILILPGLFALGMSLIDTLDGLFMRSAYGWAFRNPLGKIW
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHH
YNLTMTFISILVAYGIGTIELFGLIVSEFNLHGPFWDQINALNNVYWESIGYFVILTFAI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TWIISALIYKMKIKQLSMKKVES
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYLLFDMDNLSKKFIMWITYPNIMGSKSLTKMVFMGSFFIINIILTVIFYFILFNLPKE
CCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NLQIQTDDGVLTGTFITLGILAYTFGLRHAVDADHLAAIDNVTRKLLQEGRNPVFVGTFF
CCEEECCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEHHH
SLGHSTVVILLSLMLIIASRYIINSLPSIENVGSIIGTLISGGFLYIIAFLNTLVLLELY
HCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVYKTIRKEKNLNEKKLNELLLKRGFMNRFFNKLFKIVTSEWQMYVIGFLFGLGFDTATE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VAILAISATVAGAFSSIPITTILILPGLFALGMSLIDTLDGLFMRSAYGWAFRNPLGKIW
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHH
YNLTMTFISILVAYGIGTIELFGLIVSEFNLHGPFWDQINALNNVYWESIGYFVILTFAI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TWIISALIYKMKIKQLSMKKVES
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]