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The map label for this gene is strD [H]

Identifier: 15922683

GI number: 15922683

Start: 2352731

End: 2353507

Strand: Direct

Name: strD [H]

Synonym: ST2352

Alternate gene names: 15922683

Gene position: 2352731-2353507 (Clockwise)

Preceding gene: 15922682

Following gene: 15922685

Centisome position: 87.31

GC content: 32.69

Gene sequence:

>777_bases
ATGGTAAATAAAGCTGTAATTACTGCTGCAGGTAAAGGAAGTAGGATGAAATATATAACTTCAGTCTTGCCCAAAGCATT
ACTACCCTTATTTAGAAATGAAGAAGGAAAGATTGTAATGAGACCAGTGATTGATTTAATAATGGATTCCCTTCAAGAAG
TTGGAGTAAAGAAATTTTGTATTGTTGTGGGAAAACATGGAAAACTTTTAATGGATTATCTTTTCGAAAGGGGGGTAACT
TTTGTTTTCCAACCAGAACCTAAAGGCTTTGGCGATGCTGTATTAAGGGCTGAAGACTTCTCAAATAATGATCCCTTTTT
CGTCCATGCTGATGATGGTGTGTTAACTGGGGGTTATAGAGAAGCAAATTCGTTGTTTGAAGAAATAAAGCCTGATGCTA
TCCTTCTAGTTAGAGAAGTTAGTAATCCTAAAAGATACGGTATAGTTTCGGTAAAAGAAAAAGGAGAGTATATGGGCCAT
AAGTTATACATTGTTACACAAGCTGAAGAAAAACCTTTAGAACCTAAAAGTAATCTAGGAATATCTGCAGTATATGTCTT
TTCTCCTAAAATATTTCAAAGTTTAAAAAGGATAACAGTTGAAGAAAATAATGAATTGGAATTAACATATGGTATTCAGA
AAATAATTGAGGATGGCGGAGAAGTTTATGCCATTAAACTAGAAAAAGAAAAATGGTTGAATGTAGGTGATCCTCAAAGT
TATTATGATGCATTAATGTATTCTTATAAAAATTTAACTACTACATTCTCCATTTAG

Upstream 100 bases:

>100_bases
AGTTTTTACGTTACTGATTTTGCCCCATTAGTAAATACTTATATTGCTGCCTCAATATTTAAAGCATTAAAGAAGGCAGA
TTTAAAAAACGTGATGAAAT

Downstream 100 bases:

>100_bases
TTTTTGGTAATATAGCGTCTTTGTATCTTTCTAATCTCTCTCTATATGGTAATAAATCTTTTATCATATTCTTTAGCTCA
TCTTTTAGATTCTTCTTTGG

Product: glucose-1-phosphate thymidylyltransferase

Products: NA

Alternate protein names: Sugar-nucleotidylation enzyme; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MVNKAVITAAGKGSRMKYITSVLPKALLPLFRNEEGKIVMRPVIDLIMDSLQEVGVKKFCIVVGKHGKLLMDYLFERGVT
FVFQPEPKGFGDAVLRAEDFSNNDPFFVHADDGVLTGGYREANSLFEEIKPDAILLVREVSNPKRYGIVSVKEKGEYMGH
KLYIVTQAEEKPLEPKSNLGISAVYVFSPKIFQSLKRITVEENNELELTYGIQKIIEDGGEVYAIKLEKEKWLNVGDPQS
YYDALMYSYKNLTTTFSI

Sequences:

>Translated_258_residues
MVNKAVITAAGKGSRMKYITSVLPKALLPLFRNEEGKIVMRPVIDLIMDSLQEVGVKKFCIVVGKHGKLLMDYLFERGVT
FVFQPEPKGFGDAVLRAEDFSNNDPFFVHADDGVLTGGYREANSLFEEIKPDAILLVREVSNPKRYGIVSVKEKGEYMGH
KLYIVTQAEEKPLEPKSNLGISAVYVFSPKIFQSLKRITVEENNELELTYGIQKIIEDGGEVYAIKLEKEKWLNVGDPQS
YYDALMYSYKNLTTTFSI
>Mature_258_residues
MVNKAVITAAGKGSRMKYITSVLPKALLPLFRNEEGKIVMRPVIDLIMDSLQEVGVKKFCIVVGKHGKLLMDYLFERGVT
FVFQPEPKGFGDAVLRAEDFSNNDPFFVHADDGVLTGGYREANSLFEEIKPDAILLVREVSNPKRYGIVSVKEKGEYMGH
KLYIVTQAEEKPLEPKSNLGISAVYVFSPKIFQSLKRITVEENNELELTYGIQKIIEDGGEVYAIKLEKEKWLNVGDPQS
YYDALMYSYKNLTTTFSI

Specific function: Involved in the biosynthesis of the streptose moiety of streptomycin. Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788351, Length=252, Percent_Identity=25.3968253968254, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790224, Length=251, Percent_Identity=25.0996015936255, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005908
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 29121; Mature: 29121

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKAVITAAGKGSRMKYITSVLPKALLPLFRNEEGKIVMRPVIDLIMDSLQEVGVKKFC
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCEEEE
IVVGKHGKLLMDYLFERGVTFVFQPEPKGFGDAVLRAEDFSNNDPFFVHADDGVLTGGYR
EEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCCCCEEEECCCCEEECCCH
EANSLFEEIKPDAILLVREVSNPKRYGIVSVKEKGEYMGHKLYIVTQAEEKPLEPKSNLG
HHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCC
ISAVYVFSPKIFQSLKRITVEENNELELTYGIQKIIEDGGEVYAIKLEKEKWLNVGDPQS
EEEEEEECHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCCEEEEEEEHHHCCCCCCCHH
YYDALMYSYKNLTTTFSI
HHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MVNKAVITAAGKGSRMKYITSVLPKALLPLFRNEEGKIVMRPVIDLIMDSLQEVGVKKFC
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCEEEE
IVVGKHGKLLMDYLFERGVTFVFQPEPKGFGDAVLRAEDFSNNDPFFVHADDGVLTGGYR
EEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCCCCEEEECCCCEEECCCH
EANSLFEEIKPDAILLVREVSNPKRYGIVSVKEKGEYMGHKLYIVTQAEEKPLEPKSNLG
HHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCC
ISAVYVFSPKIFQSLKRITVEENNELELTYGIQKIIEDGGEVYAIKLEKEKWLNVGDPQS
EEEEEEECHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCCEEEEEEEHHHCCCCCCCHH
YYDALMYSYKNLTTTFSI
HHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3118332 [H]