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The map label for this gene is queC2

Identifier: 15922650

GI number: 15922650

Start: 2323150

End: 2324532

Strand: Direct

Name: queC2

Synonym: ST2318

Alternate gene names: 15922650

Gene position: 2323150-2324532 (Clockwise)

Preceding gene: 15922647

Following gene: 15922652

Centisome position: 86.21

GC content: 34.2

Gene sequence:

>1383_bases
GTGTGTAGTGTAACTGGAGTACTAATAATTAAGCCAGAAAATTATGAAAAAATAGAAAAAAAGCTTATTCAGATTCTCAA
GAGGGCAGAGGATAGAGGAAGAGACAGTTTTGGTGTTATAGTTATAGAGAAGGATGGAAGTGTAAGAAAAGTTAAAGCTT
TAGGCAGGCCTTCAACTCAAGAAGAGAAGTTATATGGTATATTAGATGAGAATTCTAAGGTGATAATAGCTAATAATAGA
GCAGAACCAACCACAGAATATGTAAGACAAAAGACAGAAGAGGATATTCAACCCTTTGAGGGAGAAAGATATATAGTTAC
GCACAACGGAATAATTGCTAACGACTTAGAATTAGAGAAAAAGTATAATGTAATAAGGAGAACTAAAATTGACAGTGCAG
TTGTTCCACCAATTTTGGATAAATATTGGAATGGAGAAATAGAACAATTAAAGAAAATACTAAATGACATTAAAGGGAGT
TTTGCGTTTATAATAGGTGATAAGAAGAGACCTAACAGAATTTACATTGCTCAGAATTTTAAGCCGGTATATATGATGTA
TGATAGAGAGTTAGGTGCTATATTCTTTACATCGCTTGATGATTATTTTGATGCCTCTGCATTTGATTCAGTAACGAAAT
TAGACCCTTACTCTATAGTAGAAGTTAATGACAATCTGGAAATTAGAAAAATTCAATTACTCGATAAGAAAATTAAAAAG
GTTCTTGTAATTGCAAGTGGTGGATTGGACTCTACTGTAGCCGCAACATACTTACTAAGGCAAGGATATGAAATCACTCT
TCTACATTTTAATTATCATCATAAAGCTGAGGAGAGAGAAAGAGAAGCCGTAAAGAAGATTGCAGAATATTTACAAGTAC
CATTAATAGAGATTGATACTGACTTGTTTAAAATTATAGGACATACCACATTACTTAAGGGTGGTGGGGAAATTGTTAAA
GATAGGCTCGGGGAAGAAGGTGCAGAATTTGCTCATGAATGGGTGCCAGCAAGGAATTTGATCTTCTATTCTGTTGCTTT
AGCATTAGCTGAGGCTTATGGGTATGATGCTATAGCTTCTGGAATAAATCTTGAAGAAGCTGGAGCTTATCCAGATAATG
AAATGGAGTTTGTACGATTATTTGCTAAACTATCTCCTTATGCTACTGGACCTAATAAAAAAGTTGAAGTTATGATGCCA
GTAGGCAATTTGGTAAAGCATGAAATTGTAAAACTTGGTGTTGAAATAGGTGCTCCACTTCATCTAACATGGAGTTGTTA
CGAAGGTGGACAAAAACATTGTGGAAAATGCGGACCTTGCTATATGAGGAAAATGGCATTTAGAATTAATGGACTTAATG
ATCCAGTAGAATATGAAAATTAG

Upstream 100 bases:

>100_bases
CGTTAAAGTAGTCTAAAGCATTCTTTACTTCATCAATTATATCCATAAATAACAAGATTGTGATAAGAAAATTTATTTTT
AAATCCTCCATTATACGAAT

Downstream 100 bases:

>100_bases
CCTTGATAATAGAAATATCTTCCTTTTCTTATCACCTTGTTTTCTCTCATTAATTGGACTAGTGCTGAATTAACTTCAGA
AGCTGGAAAATTAACATATT

Product: succinoglycan biosynthesis regulator

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase 2; Archaeosine biosynthesis protein queC 2; PreQ(0) synthase 2

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MCSVTGVLIIKPENYEKIEKKLIQILKRAEDRGRDSFGVIVIEKDGSVRKVKALGRPSTQEEKLYGILDENSKVIIANNR
AEPTTEYVRQKTEEDIQPFEGERYIVTHNGIIANDLELEKKYNVIRRTKIDSAVVPPILDKYWNGEIEQLKKILNDIKGS
FAFIIGDKKRPNRIYIAQNFKPVYMMYDRELGAIFFTSLDDYFDASAFDSVTKLDPYSIVEVNDNLEIRKIQLLDKKIKK
VLVIASGGLDSTVAATYLLRQGYEITLLHFNYHHKAEEREREAVKKIAEYLQVPLIEIDTDLFKIIGHTTLLKGGGEIVK
DRLGEEGAEFAHEWVPARNLIFYSVALALAEAYGYDAIASGINLEEAGAYPDNEMEFVRLFAKLSPYATGPNKKVEVMMP
VGNLVKHEIVKLGVEIGAPLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLNDPVEYEN

Sequences:

>Translated_460_residues
MCSVTGVLIIKPENYEKIEKKLIQILKRAEDRGRDSFGVIVIEKDGSVRKVKALGRPSTQEEKLYGILDENSKVIIANNR
AEPTTEYVRQKTEEDIQPFEGERYIVTHNGIIANDLELEKKYNVIRRTKIDSAVVPPILDKYWNGEIEQLKKILNDIKGS
FAFIIGDKKRPNRIYIAQNFKPVYMMYDRELGAIFFTSLDDYFDASAFDSVTKLDPYSIVEVNDNLEIRKIQLLDKKIKK
VLVIASGGLDSTVAATYLLRQGYEITLLHFNYHHKAEEREREAVKKIAEYLQVPLIEIDTDLFKIIGHTTLLKGGGEIVK
DRLGEEGAEFAHEWVPARNLIFYSVALALAEAYGYDAIASGINLEEAGAYPDNEMEFVRLFAKLSPYATGPNKKVEVMMP
VGNLVKHEIVKLGVEIGAPLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLNDPVEYEN
>Mature_460_residues
MCSVTGVLIIKPENYEKIEKKLIQILKRAEDRGRDSFGVIVIEKDGSVRKVKALGRPSTQEEKLYGILDENSKVIIANNR
AEPTTEYVRQKTEEDIQPFEGERYIVTHNGIIANDLELEKKYNVIRRTKIDSAVVPPILDKYWNGEIEQLKKILNDIKGS
FAFIIGDKKRPNRIYIAQNFKPVYMMYDRELGAIFFTSLDDYFDASAFDSVTKLDPYSIVEVNDNLEIRKIQLLDKKIKK
VLVIASGGLDSTVAATYLLRQGYEITLLHFNYHHKAEEREREAVKKIAEYLQVPLIEIDTDLFKIIGHTTLLKGGGEIVK
DRLGEEGAEFAHEWVPARNLIFYSVALALAEAYGYDAIASGINLEEAGAYPDNEMEFVRLFAKLSPYATGPNKKVEVMMP
VGNLVKHEIVKLGVEIGAPLHLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLNDPVEYEN

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC2_SULTO (Q96Y49)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_378319.1
- ProteinModelPortal:   Q96Y49
- GeneID:   1460401
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST2318
- NMPDR:   fig|273063.1.peg.2487
- HOGENOM:   HBG391796
- OMA:   TLLHFNY
- ProtClustDB:   CLSK883593
- BioCyc:   STOK273063:ST2318-MONOMER
- HAMAP:   MF_01633_A
- InterPro:   IPR017932
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 52195; Mature: 52195

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS51278 GATASE_TYPE_2

Important sites: ACT_SITE 2-2

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSVTGVLIIKPENYEKIEKKLIQILKRAEDRGRDSFGVIVIEKDGSVRKVKALGRPSTQ
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHCCCCCCC
EEKLYGILDENSKVIIANNRAEPTTEYVRQKTEEDIQPFEGERYIVTHNGIIANDLELEK
CCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCEEECCCHHHH
KYNVIRRTKIDSAVVPPILDKYWNGEIEQLKKILNDIKGSFAFIIGDKKRPNRIYIAQNF
HHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECC
KPVYMMYDRELGAIFFTSLDDYFDASAFDSVTKLDPYSIVEVNDNLEIRKIQLLDKKIKK
CEEEEEEECCCCEEEEECHHHHCCCHHHHHHHCCCCEEEEEECCCCEEEHHHHHHHHHHE
VLVIASGGLDSTVAATYLLRQGYEITLLHFNYHHKAEEREREAVKKIAEYLQVPLIEIDT
EEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECH
DLFKIIGHTTLLKGGGEIVKDRLGEEGAEFAHEWVPARNLIFYSVALALAEAYGYDAIAS
HHHHHHCCHHEECCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHC
GINLEEAGAYPDNEMEFVRLFAKLSPYATGPNKKVEVMMPVGNLVKHEIVKLGVEIGAPL
CCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCE
HLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLNDPVEYEN
EEEEEHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MCSVTGVLIIKPENYEKIEKKLIQILKRAEDRGRDSFGVIVIEKDGSVRKVKALGRPSTQ
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHCCCCCCC
EEKLYGILDENSKVIIANNRAEPTTEYVRQKTEEDIQPFEGERYIVTHNGIIANDLELEK
CCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCEEECCCHHHH
KYNVIRRTKIDSAVVPPILDKYWNGEIEQLKKILNDIKGSFAFIIGDKKRPNRIYIAQNF
HHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECC
KPVYMMYDRELGAIFFTSLDDYFDASAFDSVTKLDPYSIVEVNDNLEIRKIQLLDKKIKK
CEEEEEEECCCCEEEEECHHHHCCCHHHHHHHCCCCEEEEEECCCCEEEHHHHHHHHHHE
VLVIASGGLDSTVAATYLLRQGYEITLLHFNYHHKAEEREREAVKKIAEYLQVPLIEIDT
EEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECH
DLFKIIGHTTLLKGGGEIVKDRLGEEGAEFAHEWVPARNLIFYSVALALAEAYGYDAIAS
HHHHHHCCHHEECCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHC
GINLEEAGAYPDNEMEFVRLFAKLSPYATGPNKKVEVMMPVGNLVKHEIVKLGVEIGAPL
CCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCE
HLTWSCYEGGQKHCGKCGPCYMRKMAFRINGLNDPVEYEN
EEEEEHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479